2,186 research outputs found
Decoupling method for dynamical mean field theory calculations
In this paper we explore the use of an equation of motion decoupling method
as an impurity solver to be used in conjunction with the dynamical mean field
self-consistency condition for the solution of lattice models. We benchmark the
impurity solver against exact diagonalization, and apply the method to study
the infinite Hubbard model, the periodic Anderson model and the model.
This simple and numerically efficient approach yields the spectra expected for
strongly correlated materials, with a quasiparticle peak and a Hubbard band. It
works in a large range of parameters, and therefore can be used for the
exploration of real materials using LDA+DMFT.Comment: 30 pages, 7 figure
Differential Expression of CRH, UCN, CRHR1 and CRHR2 in Eutopic and Ectopic Endometrium of Women with Endometriosis.
Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors. Corticotropin releasing hormone (CRH) and urocortin (UCN) are neuropeptides, strongly related to stress and inflammation. The effects of CRH and UCN are mediated through CRHR1 and CRHR2 receptors which are implicated in several reproductive functions acting as inflammatory components. However, the involvement of these molecules to endometriosis remains unknown. The aim of this study was to examine the expression of CRHR1 and CRHR2 in endometriotic sites and to compare the expression of CRHR1 and CRHR2 in eutopic endometrium of endometriotic women to that of healthy women. We further compared the expression of CRH, UCN, CRHR1 and CRHR2 in ectopic endometrium to that in eutopic endometrium of women with endometriosis. Endometrial biopsy specimens were taken from healthy women (10 patients) and endometrial and endometriotic biopsy specimens were taken from women with endometriosis (16 patients). Τhe expression of CRH, UCN, CRHR1, and CRHR2 was tested via RT-PCR, immunohistochemistry and Western blotting. This study shows for the first time that CRH and UCN receptor subtypes CRHR1β and CRHR2α are expressed in endometriotic sites and that they are more strongly expressed (p<0.01) in eutopic endometrium of women with endometriosis compared to healthy women endometrium at the mRNA and protein level. CRH, UCN, CRHR1 and CRHR2 mRNA were also more highly expressed in ectopic rather than eutopic endometrium (CRH, UCN, CRHR2α: p<0.01, CRHR1β: p<0.05) and protein (CRH and UCN: p<0.05, CRHR1 and CRHR2: p<0.01) in women with endometriosis. These data indicate that CRH and UCN might play an immunoregulatory role in endometriotic sites by affecting reproductive functions such as decidualization and implantation of women with endometriosis
Himalayan and Trans-Himalayan Glacier Fluctuations Since AD 1812
Historical records of the fluctuations of glaciers in the Himalayas and Trans-Himalayas date back to the early 19th century. Local and regional syntheses of 112 of these fluctuation records are presented in this study. The local syntheses deal with fluctuations of glaciers in Kanchenjunga-Everest, Garwhal, Lahaul-Spiti, Kolahoi, Nanga Parbat, Karakoram (north and south sides), Rakaposhi-Haramosh, Batura Mustagh, and Khunjerab-Ghujerab. Regional syntheses deal with the composite record and the differentiation of records by glacier type (longitudinal versus transverse) and regional setting (Himalayan versus Trans-Himalayan). In a gross regional sense Himalayan and Trans-Himalayan glaciers have been in a general state of retreat since AD 1850. Filtering of the fluctuation records with respect to glacier type and regional setting reveals that the period AD 1870 to 1940 was characterized by alternations in the dominancy of retreat, advance, and standstill regimes
Electronic properties of Fabre charge-transfer salts under various temperature and pressure conditions
Using density functional theory, we determine parameters of tight-binding
Hamiltonians for a variety of Fabre charge transfer salts, focusing in
particular on the effects of temperature and pressure. Besides relying on
previously published crystal structures, we experimentally determine two new
sets of structures; (TMTTF)SbF at different temperatures and
(TMTTF)PF at various pressures. We find that a few trends in the
electronic behavior can be connected to the complex phase diagram shown by
these materials. Decreasing temperature and increasing pressure cause the
systems to become more two-dimensional. We analyze the importance of
correlations by considering an extended Hubbard model parameterized using
Wannier orbital overlaps and show that while charge order is strongly activated
by the inter-site Coulomb interaction, the magnetic order is only weakly
enhanced. Both orders are suppressed when the effective pressure is increased.Comment: 12 pages, 16 figure
Lichenometric Distribution of \u3cem\u3eRhizocarpon geographicum\u3c/em\u3e on Mt. Washington: A Relative Dating Tool.
Excerpt from summary, p. 83: In addition to marking the distribution of snowpatches and the relative age of patterned ground features, local departures from the regional lichenometric trend may also be used to define and relatively date: changes in the distribution of soils and vegetation, avalanche deposits, and abrasion of hiking trails. Lichenometric studies will be undertaken in the following year to date more precisely features and events on Mount Washington
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects. Progesterone is thought to mediate some of these effects by regulating uterine responsiveness. The aim of this study was to clarify the effect of amniotic fluid transferrin and its N-glycans on the release of progesterone by first trimester trophoblast cells in vitro. Methods: Cytotrophoblast cells were prepared from human first trimester placentae by trypsin-DNAse dispersion of villous tissue followed by a percoll gradient centrifugation and depletion of CD45 positive cells by magnetic cell sorting. Trophoblasts were incubated with varying concentrations (50-300 mug/ml) of transferrin from human amniotic fluid and serum as well as with N-glycans obtained from amniotic fluid transferrin. Culture supernatants were assayed for progesterone by enzyme-immunometric methods. Results: The release of progesterone increased in amniotic fluid transferrin- and N-glycan-treated trophoblast cell cultures compared to untreated trophoblast cells. There was no stimulating effect of serum transferrin on the progesterone production of trophoblast cells. Conclusions: The results suggest that amnion-transferrin and especially its N-glycans modulate the endocrine function of trophoblasts in culture by up regulating progesterone secretion
Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system
Devising new and more efficient protocols to analyze the phenotypes of non-human primates, as well as their complex nervous systems, is rapidly becoming of paramount importance. This is because with genome-editing techniques, recently adopted to non-human primates, new animal models for fundamental and translational research have been established. One aspect in particular, namely cognitive hearing, has been difficult to assess compared to visual cognition. To address this, we devised autonomous, standardized, and unsupervised training and testing of auditory capabilities of common marmosets with a cage-based standalone, wireless system. All marmosets tested voluntarily operated the device on a daily basis and went from naïve to experienced at their own pace and with ease. Through a series of experiments, here we show, that animals autonomously learn to associate sounds with images; to flexibly discriminate sounds, and to detect sounds of varying loudness. The developed platform and training principles combine in-cage training of common marmosets for cognitive and psychoacoustic assessment with an enriched environment that does not rely on dietary restriction or social separation, in compliance with the 3Rs principle
The monoclinic crystal structure of -RuCl and the zigzag antiferromagnetic ground state
The layered honeycomb magnet alpha-RuCl3 has been proposed as a candidate to
realize a Kitaev spin model with strongly frustrated, bond-dependent,
anisotropic interactions between spin-orbit entangled jeff=1/2 Ru4+ magnetic
moments. Here we report a detailed study of the three-dimensional crystal
structure using x-ray diffraction on untwinned crystals combined with
structural relaxation calculations. We consider several models for the stacking
of honeycomb layers and find evidence for a crystal structure with a monoclinic
unit cell corresponding to a stacking of layers with a unidirectional in-plane
offset, with occasional in-plane sliding stacking faults, in contrast with the
currently-assumed trigonal 3-layer stacking periodicity. We report electronic
band structure calculations for the monoclinic structure, which find support
for the applicability of the jeff=1/2 picture once spin orbit coupling and
electron correlations are included. We propose that differences in the
magnitude of anisotropic exchange along symmetry inequivalent bonds in the
monoclinic cell could provide a natural mechanism to explain the spin gap
observed in powder inelastic neutron scattering, in contrast to spin models
based on the three-fold symmetric trigonal structure, which predict a gapless
spectrum within linear spin wave theory. Our susceptibility measurements on
both powders and stacked crystals, as well as neutron powder diffraction show a
single magnetic transition at TN ~ 13K. The analysis of the neutron data
provides evidence for zigzag magnetic order in the honeycomb layers with an
antiferromagnetic stacking between layers. Magnetization measurements on
stacked single crystals in pulsed field up to 60T show a single transition
around 8T for in-plane fields followed by a gradual, asymptotic approach to
magnetization saturation, as characteristic of strongly anisotropic exchange
interactions.Comment: 13 pages, 9 figures, published in Physical Review
A valence bond liquid on the honeycomb lattice
The honeycomb lattice material Li2RuO3 undergoes a dimerization of Ru4+
cations on cooling below 270C, where the magnetic susceptibility vanishes. We
use density functional theory calculations to show that this reflects the
formation of a 'valence bond crystal', with a strong bond disproportionation.
On warming, x-ray diffraction shows that discrete three-fold symmetry is
regained on average, and the dimerization apparently disappears. In contrast,
local structural measurements using high-energy x-rays, show that disordered
dimers survive at the nanoscale up to at least 650C. The high temperature phase
of Li2RuO3 is thus an example of a valence bond liquid, where thermal
fluctuations drive resonance between different dimer coverages, a classic
analogue of the resonating valence bond state often discussed in connection
with high T cuprates.Comment: 5 pages, 4 figures, References correcte
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