Laboratory Findings of COVID-19 Infection are Conflicting in Different Age Groups and Pregnant Women: A Literature Review

Coronavirus disease 2019 (COVID-19), a new type and rapidly spread viral pneumonia, is now producing an outbreak of pandemic proportions. The clinical features and laboratory results of different age groups are different due to the general susceptibility of the disease. The laboratory findings of COVID-19 in pregnant women are also conflicting. Para-clinical investigations including laboratory tests and radiologic findings play an important role in early diagnosis and treatment monitoring of COVID-19. The majority of previous reports on the COVID-19 laboratory results were based on data from the general population and limited information is available based on age difference and pregnancy status. This review aimed to describe the COVID-19 laboratory findings in neonates, children, adults, elderly and pregnant women altogether for the first time. The most attracting and reliable markers of COVID-19 in patients were: normal C-reactive protein (CRP) and very different and conflicting laboratory results regardless of clinical symptoms in neonates, normal or temporary elevated CRP, conflicting WBC count results and procalcitonin elevation in children, lymphopenia and elevated lactate dehydrogenase (LDH) in adult patients, lymphopenia and elevated CRP and LDH in the elderly people, leukocytosis and elevated neutrophil ratio in pregnant women. © 2020 IMS

Beneficial effects of Achillea millefolium on skin injuries; a literature review

Various plants and natural compounds have been used traditionally to treat and prevent diseases, relieve pain, increase body strength, and heal skin injury. Achillea millefolium is a well-known plant of the Asteraceae family that has been extensively studied for its therapeutic properties in conditions, such as menstrual disorders, malaria, headache, cough, and skin injury. Several studies have shown that the topical application of different types of A. millefolium extracts (essential oil (EO), hydroalcoholic extract, etc.) improves the healing process of various skin injuries. Previous studies also highlighted the antibacterial, anti-inflammatory, antioxidant, and moisturizing effects of the A. millefolium extract on ameliorating skin injuries, caused by the presence of various potent constituents in the plant extract. This review aimed at overviewing the studies, focusing on A. millefolium's possible effects on the different wound injuries

Beneficial effects of Achillea millefolium on skin injuries; a literature review

Various plants and natural compounds have been used traditionally to treat and prevent diseases, relieve pain, increase body strength, and heal skin injury. Achillea millefolium is a well-known plant of the Asteraceae family that has been extensively studied for its therapeutic properties in conditions, such as menstrual disorders, malaria, headache, cough, and skin injury. Several studies have shown that the topical application of different types of A. millefolium extracts (essential oil (EO), hydroalcoholic extract, etc.) improves the healing process of various skin injuries. Previous studies also highlighted the antibacterial, anti-inflammatory, antioxidant, and moisturizing effects of the A. millefolium extract on ameliorating skin injuries, caused by the presence of various potent constituents in the plant extract. This review aimed at overviewing the studies, focusing on A. millefolium's possible effects on the different wound injuries

Multi-objective Aggregate Production Planning Model Considering Overtime and Outsourcing Options Under Fuzzy Seasonal Demand

This paper investigates a novel fuzzy multi-objective multi-period Aggregate Production Planning (APP) problem under seasonal demand. As two of the main real-world assumptions, the options of workforce overtime and outsourcing are studied in the proposed Mixed-Integer Linear Programming (MILP) model. The main goals are to minimize the total cost including in-house production, outsourcing, workforce, holding, shortage and employment/ unemployment costs, and maximize the customers' satisfaction level. To deal with demand uncertainty, triangular fuzzy numbers are considered for demand parameters. Then the proposed model is validated by solving an illustrative example using a Weighted Goal Programming (WGP) method and CPLEX solver. Finally, it is demonstrated that uncertain conditions and considering real-world assumptions can yield different results in developing a practical aggregate production plan. Moreover, a sensitivity analysis is then performed to provide qualitative managerial insights and decision aids