156 research outputs found

    Hadron formation in high energy photonuclear reactions

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    We present a new method to account for coherence length effects in a semi-classical transport model. This allows us to describe photo- and electroproduction at large nuclei (A>12) and high energies using a realistic coupled channel description of the final state interactions that goes beyond simple Glauber theory. We show that the purely absorptive treatment of the final state interactions can lead to wrong estimates of color transparency and formation time effects in particle production. As an example, we discuss exclusive rho^0 photoproduction on Pb at a photon energy of 7 GeV as well as K^+ production in the photon energy range 1-7 GeV.Comment: 14 pages, 6 figures, version published in Phys. Rev.

    Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis

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    Background. Long-term hematopoietic stem cells (LT-HSCs) reside in bone marrow niches with tightly controlled reactive oxygen species (ROS) levels. ROS increase results into LT-HSC differentiation and stem cell exhaustion. Paraoxonase 2 (PON2) has been shown to be important for ROS control. Objectives. We investigate the effects of inactivation of the PON2 gene on hematopoietic cell differentiation and activity. Methods and Results. In young mice with inactivated Pon2 gene (Pon2-/-, -/- BM outcompeted WT BM at early time points. ROS levels were significantly increased in Pon2-/- whole BM, but not in Pon2-/- LT-HSCs. In more differentiated stages of hematopoiesis, Pon2 deficiency led to a misbalanced erythropoiesis both in physiologic and stress conditions. In older mice (>9 months), Pon2 depletion caused an increase in LT-HSCs as well as increased levels of granulocyte/macrophage progenitors (GMPs) and myeloid skewing, indicating a premature aging phenotype. No significant changes in ROS levels in old Pon2-/- LT- and short-term (ST-) HSCs were observed, but a significant reduction of spontaneous apoptotic cell death was measured. RNA-seq analysis in Pon2-/- LT-HSCs identified overrepresentation of genes involved in the C-X-C chemokine receptor type 4 (Cxcr4) signaling, suggesting compensatory mechanisms to overcome ROS-mediated accelerated aging in hematopoietic progenitor cells. Conclusions. In summary, our current data indicate that PON2 is involved in the regulation of HSC functions

    Rethinking naive realism

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    Perceptions are externally-directed - they present us with a mind-independent reality, and thus contribute to our abilities to think about this reality, and to know what is objectively the case. But perceptions are also internally-dependent - their phenomenal characters depend on the neuro-computational properties of the subject. A good theory of perception must account for both these facts. But Naive realism has been criticized for failing to accommodate the latter one. This paper evaluates and responds to this criticism. It first argues that a certain version of naive realism, often called “selectionism”, does indeed struggle with the internal-dependence of perceptions. It then develops an alternate version of naive realism which does not. This alternate version, inspired by an idea of Martin's, accommodates the internal-dependence of perceptions by recognizing the role that the subject's neuro-computational properties play in shaping perceptual phenomenology. At the same time, it retains the distinctive naive realist account of the external-directedness of perceptions

    Shadowing in the nuclear photoabsorption above the resonance region

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    A model based on the hadronic fluctuations of the real photon is developed to describe the total photonucleon and photonuclear cross sections in the energy region above the nucleon resonances. The hadronic spectral function of the photon is derived including the finite width of vector-meson resonances and the quark-antiquark continuum. The shadowing effect is evaluated considering the effective interaction of the hadronic component with the bound nucleons within a Glauber-Gribov multiple scattering theory. The low energy onset of the shadowing effect is interpreted as a possible signature of a modification of the hadronic spectral function in the nuclear medium. A decrease of the ρ\rho-meson mass in nuclei is suggested for a better explanation of the experimental data.Comment: 8 pages, 7 figure

    Shadowing in photo-production : role of in-medium hadrons

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    We study the effects of in-medium hadronic properties on shadowing in photon-nucleus interactions in Glauber model as well as in the multiple scattering approach. A reasonable agreement with the experimental data is obtained in a scenario of downward spectral shift of the hadrons. Shadowing is found to be insensitive to the broadening of the spectral functions. An impact parameter dependent analysis of shadowing might shed more light on the role of in-medium properties of hadrons.Comment: Title modified; version to appear in PRC, Rapid Communication

    Extracting the dipole cross-section from photo- and electro-production total cross-section data

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    We report on a successful attempt to extract the cross-section for the high-energy scattering of colour dipoles of fixed transverse size off protons using electroproduction and photoproduction total cross-section data, subject to the constraint provided by the ratio of the overall photon dissociation cross-section to the total cross-section.Comment: LaTeX2e, 29 pages, 11 figures, submitted to Phys Rev D. Because of error in parameter assignment, one parameter removed and tables of parameter fits and affected figs 2, 4-9 replaced. Error in figure caption corrected. Reference update

    ω(π+ππ0) \omega (\to \pi^+\pi^-\pi^0) meson photoproduction on proton

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    The cross section is estimated for the π+ππ0\pi^+\pi^-\pi^0 invariant mass distribution in the γp\gamma p reaction in the GeV region. This reaction is assumed to proceed through the formation of the ω\omega meson in the intermediate state, since the production cross section for this meson in the γp\gamma p reaction in GeV region is significant and it has large branching ratio (88.8%) in the π+ππ0\pi^+\pi^-\pi^0 channel. The cross sections for this reaction have been calculated using the energy dependent reaction amplitude, i.e., fγpωp(0)f_{\gamma p \to \omega p}(0), extracted from the latest ω\omega meson photoproduction data. We use established procedure to calculate other factors, like width and propagator of the ω\omega meson, so that our calculation can provide reliable cross section. The calculated results reproduce the measured π+ππ0\pi^+\pi^-\pi^0 invariant mass distribution spectra in the γp\gamma p reaction.Comment: 13 pages, 5 figure
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