Diabetic ketoacidosis in a hospital based population in Pakistan

Sixty-two consecutive episodes of diabetic ketoacidosis (DKA) were studied at Aga Khan University Hospital, Karachi. Forty-four (71%) were type I and 18 (29%) type II diabetics. Mean age was 28.1 years and mean duration of diabetes 4.1 years. Infections were the most common precipitating factor accounting for 28 episodes (45.2%). Twenty-two patients (35.5%) had hyperosmolality (serum osmolality \u3e 320 mosmol/L). Mean serum Na+ was 131.7 mmol/L and K+ 4.6 mmol/L. Twenty-three (37.1%) were hyperkalemic at presentation with seven patients (11.3%) being comatosed and 35 (56.5%) alert. Mean random blood glucose (RBG) was 624 mg/dl, mean pN 7.09, osmolality 316 mosmol/L and the neurological status correlated statistically significantly with mean RBG, pH and osmolality. A leukemoid response was seen in 83.9% episodes. Mortality rate was 8.0% in patients with DKA managed in this hospital

Non-financial disclosure and market-based firm performance: The initiation of financial inclusion

We examine the association between financial inclusion disclosure and firm performance in Bangladeshi banks from 2009 to 2014 in response to a regulatory directive on the engagement of banking firms in financial inclusion activities. We find a positive association between financial inclusion disclosure and banking firms’ subsequent performance, with this relationship moderated by market competition and government ownership. We also find evidence that firms’ engagement in financial inclusion activities increases their market share, with the disclosure of this information reducing the information asymmetry between managers and capital market participants. The broad implication of our research findings is that firms considering investing in financial inclusion activities could benefit from improved firm performance and gain market share. The research findings contribute to the larger debate on the reasons why firms should consider incorporating these initiatives into their operational activities. In addition, the findings inform various international organisations that promote financial inclusion activities

Fructosamine: an alternative assessment of past glycaemic control in developing countries

Fructosamine assay determines glycaemic control in diabetic patients by measuring glycosylated plasma protein. This study was done to assess the value of fructosamine as an alternative test to HbA1c as a measure of glycaemia. Sixty patients (both insulin dependent diabetes mellitus and non insulin dependent diabetes mellitus) were selected from the diabetic clinic and fasting blood samples were collected for estimation of glucose, HbA1c and fructosamine levels. The results were compared by correlation analysis and major discrepancies/discordance was detected by dividing the results into 3 clinical categories and detecting the cases in which the values fell in opposite clinical categories. Fructosamine correlated well with HbA1c (r = 0.41, p \u3c 0.01) and with fasting blood glucose (r = 0.45 p \u3c 0.01). Major discordance was detected in the results of only 7 patients which can partly be attributed to different periods over which HbA1c and fructosamine reflect average glycaemia. Fructosamine measures glycaemia over the past 2-3 weeks and HbA1c over 8 weeks. As fructosamine assay is relatively inexpensive, reliable and simple to perform; it can be used as an alternative to HbA1c and is particularly suited for developing countries

(2Z)-2-(4-Methyl­phen­yl)-3-(2-naphth­yl)prop-2-enenitrile

In the title compound, C20H15N, the dihedral angle between the naphthalene and benzene rings is 60.30 (16)°. The crystal packing features very weak inter­molecular C—H⋯π inter­actions

Changes in Color and Physiological Components of The Postharvest Mango (Mangifera indica L.) Influenced by Different Levels of GA3

Abstract - This experiment consisted of two popular mango varieties in Bangladesh (viz., Langra and Khirshapat) and four different levels of Gibberellic acid (GA3) solution, namely control, 100, 200 and 400 ppm. The two factors experiment was assigned in randomized complete block design with tree replicates. Data obtained from various biochemical analyses in terms of physicochemical properties and shelf life of postharvest mango, were recorded and statistically analyzed for comparison among the mean values using DMRT and LSD. The results of the experiments exhibited that only the single effect of varieties was found to be significant in most of the parameters studied. Variety the Langra performed better in accumulating higher quantity of dry matter, ash, vitamin c content in all four experiments over Khirshapat. On the other hand, the Khirshapat showed better performance in achieving higher quantity of moisture, progressively lost physiological weight as well as extended shelf life and delayed skin color changes than Langra at all the storage duration. Keywords: Postharvest mango; Gibberellic acid; physiological components