21 research outputs found

    LWBtheory: Information about some propositional logics via the WWW

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    Imagine that you are not sure how the Hilbert-style calculus for S4 looks like, and somebody has taken your book about modal logics off your desk. No problem if you have an internet access: Open http://lwbwww.unive.ch:8080/LWBtheory.html, in a WWW browser, search for Hilbert-style calculus, in the chapter about S4, and after a few seconds you obtain the calculus, together with an example of a proof of a formula in this calculus. LWBtheory contains only a relatively small amount of information concerning some propositional non-classical logics and non-monotonic systems. However, even if your favourite subjects are not covered, it can be of some interest to you, since it shows the today's possibilities and can help to obtain improved, more comprehensive systems in the futur

    Practical Verification of Decision-Making in Agent-Based Autonomous Systems

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    We present a verification methodology for analysing the decision-making component in agent-based hybrid systems. Traditionally hybrid automata have been used to both implement and verify such systems, but hybrid automata based modelling, programming and verification techniques scale poorly as the complexity of discrete decision-making increases making them unattractive in situations where complex log- ical reasoning is required. In the programming of complex systems it has, therefore, become common to separate out logical decision-making into a separate, discrete, component. However, verification techniques have failed to keep pace with this devel- opment. We are exploring agent-based logical components and have developed a model checking technique for such components which can then be composed with a sepa- rate analysis of the continuous part of the hybrid system. Among other things this allows program model checkers to be used to verify the actual implementation of the decision-making in hybrid autonomous systems

    Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry

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    BACKGROUND: Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct elemental compositions. In order to automatically constrain the thousands of possible candidate structures, rules need to be developed to select the most likely and chemically correct molecular formulas. RESULTS: An algorithm for filtering molecular formulas is derived from seven heuristic rules: (1) restrictions for the number of elements, (2) LEWIS and SENIOR chemical rules, (3) isotopic patterns, (4) hydrogen/carbon ratios, (5) element ratio of nitrogen, oxygen, phosphor, and sulphur versus carbon, (6) element ratio probabilities and (7) presence of trimethylsilylated compounds. Formulas are ranked according to their isotopic patterns and subsequently constrained by presence in public chemical databases. The seven rules were developed on 68,237 existing molecular formulas and were validated in four experiments. First, 432,968 formulas covering five million PubChem database entries were checked for consistency. Only 0.6% of these compounds did not pass all rules. Next, the rules were shown to effectively reducing the complement all eight billion theoretically possible C, H, N, S, O, P-formulas up to 2000 Da to only 623 million most probable elemental compositions. Thirdly 6,000 pharmaceutical, toxic and natural compounds were selected from DrugBank, TSCA and DNP databases. The correct formulas were retrieved as top hit at 80–99% probability when assuming data acquisition with complete resolution of unique compounds and 5% absolute isotope ratio deviation and 3 ppm mass accuracy. Last, some exemplary compounds were analyzed by Fourier transform ion cyclotron resonance mass spectrometry and by gas chromatography-time of flight mass spectrometry. In each case, the correct formula was ranked as top hit when combining the seven rules with database queries. CONCLUSION: The seven rules enable an automatic exclusion of molecular formulas which are either wrong or which contain unlikely high or low number of elements. The correct molecular formula is assigned with a probability of 98% if the formula exists in a compound database. For truly novel compounds that are not present in databases, the correct formula is found in the first three hits with a probability of 65–81%. Corresponding software and supplemental data are available for downloads from the authors' website

    LWBtheory: Information about some propositional logics via the WWW

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    KtSeqC : System Description

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    Freianlagen: Ausführung

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    Bautechnische Grundlagen für Freianlagen. Auswahlkriterien, Regelaufbauten, Pflege- und Unterhaltshinweise für Sportbeläge. Angaben über Beleuchtungs-, Beschallungs- und andere Einrichtungen, Nebenanlagen und Umgebungsarbeiten

    Generic modal cut elimination applied to conditional logics

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    We develop a general criterion for cut elimination in sequent calculi for propositional modal logics, which rests on absorption of cut, contraction, weakening and inversion by the purely modal part of the rule system. Our criterion applies also to a wide variety of logics outside the realm of normal modal logic. We give extensive example instantiations of our framework to various conditional logics. For these, we obtain fully internalised calculi which are substantially simpler than those known in the literature, along with leaner proofs of cut elimination and complexity. In one case, conditional logic with modus ponens and conditional excluded middle, cut elimination and complexity are explicitly stated as open in the literature
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