Four dimensional observations of clouds from geosynchronous orbit using stereo display and measurement techniques on an interactive information processing system

Simultaneous Geosynchronous Operational Environmental Satellite (GOES) 1 km resolution visible image pairs can provide quantitative three dimensional measurements of clouds. These data have great potential for severe storms research and as a basic parameter measurement source for other areas of meteorology (e.g. climate). These stereo cloud height measurements are not subject to the errors and ambiguities caused by unknown cloud emissivity and temperature profiles that are associated with infrared techniques. This effort describes the display and measurement of stereo data using digital processing techniques

Impact Ionization and Hot-Electron Injection Derived Consistently from Boltzmann Transport

We develop a quantitative model of the impact-ionizationand hot-electron–injection processes in MOS devices from first principles. We begin by modeling hot-electron transport in the drain-to-channel depletion region using the spatially varying Boltzmann transport equation, and we analytically find a self consistent distribution function in a two step process. From the electron distribution function, we calculate the probabilities of impact ionization and hot-electron injection as functions of channel current, drain voltage, and floating-gate voltage. We compare our analytical model results to measurements in long-channel devices. The model simultaneously fits both the hot-electron- injection and impact-ionization data. These analytical results yield an energydependent impact-ionization collision rate that is consistent with numerically calculated collision rates reported in the literature

Integration of production and financial models to analyse the financial impact of livestock diseases: a case study of Schmallenberg virus disease on British and French dairy farms

AIMS AND OBJECTIVES: The aim of the study was to investigate and compare the financial impact of Schmallenberg disease for different dairy production types in the United Kingdom and France. MATERIALS AND METHODS: Integrated production and financial models for dairy cattle were developed and applied to Schmallenberg virus (SBV) disease in a British and French context. The five main production systems that prevail in these two countries were considered. Their respective gross margins measuring the holding's profitability were calculated based on public benchmarking, literature and expert opinion data. A partial budget analysis was performed within each production model to estimate the impact of SBV in the systems modelled. Two disease scenarios were simulated: low impact and high impact. RESULTS: The model gross margin obtained per cow space and year ranged from £1014 to £1484 for the UK and from £1037 to £1890 for France depending on the production system considered. In the UK, the net SBV disease costs in £/cow space/year for an average dairy farm with 100 milking spaces were estimated between £16.3 and £51.4 in the high-impact scenario and between £8.2 and £25.9 in the low-impact scenario. For France, the net SBV disease costs in £/cow space/year ranged from £19.6 to £48.6 in the high-impact scenario and £9.7 to £22.8 in the low-impact scenario, respectively. CONCLUSION: The study illustrates how the combination of production and financial models allows assessing disease impact taking into account differing management and husbandry practices and associated price structures in the dairy sector. It supports decision-making of farmers and veterinarians who are considering disease control measures as it provides an approach to estimate baseline disease impact in common dairy production systems in the UK and France

Wind estimates from cloud motions: Preliminary results from phases 1, 2, and 3 of an in situ aircraft verification experiment

Low level aircraft equipped with Inertial Navigation Systems (INS) were used to define the vertical extent and horizontal motion of a cloud and to measure the ambient wind field. A high level aircraft, also equipped with an INS, took photographs to describe the horizontal extent of the cloud field and to measure cloud motion. The aerial photographs were also used to make a positive identification in a satellite picture of the cloud observed by the low level aircraft. The experiment was conducted over the tropical oceans in the vicinity of Florida, Puerto Rico, Panama and in the Western Gulf of Mexico. Results for tropical cumulus clouds indicate excellent agreement between the cloud motion and the wind at the cloud base. The magnitude of the vector difference between the cloud motion and the cloud base wind is less than 1.3 m/sec for 67% of the cases with track lengths of 1 hour or longer. The cirrus cloud motions agreed best with the mean wind in the cloud layer with a vector difference of about 1.6 m/sec

A dunnett-type procedure for multiple endpoints

This paper describes a method for comparisons of several treatments with a control, simultaneously for multiple endpoints. These endpoints are assumed to be normally distributed with different scales and variances. An approximate multivariate t-distribution is used to obtain quantiles for test decisions, multiplicity-adjusted p-values, and simultaneous confidence intervals. Simulation results show that this approach controls the family-wise error type I over both the comparisons and the endpoints in an admissible range. The approach will be applied to a randomized clinical trial comparing two new sets of extracorporeal circulations with a standard for three primary endpoints. A related R package is available. © 2011 Berkeley Electronic Press. All rights reserved

Shot noise of a quantum dot measured with GHz stub impedance matching

The demand for a fast high-frequency read-out of high impedance devices, such as quantum dots, necessitates impedance matching. Here we use a resonant impedance matching circuit (a stub tuner) realized by on-chip superconducting transmission lines to measure the electronic shot noise of a carbon nanotube quantum dot at a frequency close to 3 GHz in an efficient way. As compared to wide-band detection without impedance matching, the signal to noise ratio can be enhanced by as much as a factor of 800 for a device with an impedance of 100 k$\Omega$. The advantage of the stub resonator concept is the ease with which the response of the circuit can be predicted, designed and fabricated. We further demonstrate that all relevant matching circuit parameters can reliably be deduced from power reflectance measurements and then used to predict the power transmission function from the device through the circuit. The shot noise of the carbon nanotube quantum dot in the Coulomb blockade regime shows an oscillating suppression below the Schottky value of $2eI$, as well an enhancement in specific regions.Comment: 6 pages, 4 figures, supplementar

Locating the Source of Diffusion in Large-Scale Networks

How can we localize the source of diffusion in a complex network? Due to the tremendous size of many real networks--such as the Internet or the human social graph--it is usually infeasible to observe the state of all nodes in a network. We show that it is fundamentally possible to estimate the location of the source from measurements collected by sparsely-placed observers. We present a strategy that is optimal for arbitrary trees, achieving maximum probability of correct localization. We describe efficient implementations with complexity O(N^{\alpha}), where \alpha=1 for arbitrary trees, and \alpha=3 for arbitrary graphs. In the context of several case studies, we determine how localization accuracy is affected by various system parameters, including the structure of the network, the density of observers, and the number of observed cascades.Comment: To appear in Physical Review Letters. Includes pre-print of main paper, and supplementary materia

Serious bacterial infections in patients with rheumatoid arthritis under anti‐TNF‐α therapy

Objective. With rising numbers of anti‐tumour necrosis factor α (TNF‐α) treatments for rheumatoid arthritis (RA), Crohn's disease and other conditions, physicians unaware of potential pitfalls are increasingly likely to encounter associated severe infections. Our purpose was to assess the incidence and nature of severe infections in our RA patients under anti‐TNF‐α therapy. Methods. We reviewed patient charts and records of the Infectious Disease Unit for serious infections in patients with RA in the 2 yr preceding anti‐TNF‐α therapy and during therapy. Results. Serious infections affected 18.3% of patients treated with infliximab or etanercept. The incidence was 0.181 per anti‐TNF‐α treatment year vs 0.008 in the 2 yr preceding anti‐TNF‐α therapy. In several cases, only a few signs or symptoms indicated the severity of developing infections, including sepsis. Conclusions. A high level of suspicion of infection is necessary in patients under anti‐TNF‐α therapy. We suggest additional strategies for the prevention, rapid identification and pre‐emptive therapy of such infection