Innovation in the energy sector: advancing or frustrating climate policy goals?

The energy sector is well known for the relatively modest level of resource that it devotes to research and development (R&D). However, the incremental pace of energy innovation has speeded up in the last decade as measured by public sector R&D budgets, deployment of alternative technologies and novel institutional arrangements. While much of this effort has been targeted at technologies that promise to reduce carbon dioxide (CO2) emissions, there have also been major innovations that extend the fossil fuel resource base and reduce the cost of extraction. The last decade’s developments can be seen in terms of a challenge to the existing energy paradigm in parallel with a renewed innovative response focusing on conventional fuels and technologies. This paper examines this tension, by exploring the expectations of a variety of organisations in both the public and private sector regarding energy sector developments and by analysing private sector expenditure on energy research and development (R&D) and public sector budgets for energy R&D and demonstration (RD&D). Scenarios and outlook exercises that have been published since 2013 reveal a wide range of beliefs about the future development of the energy system. The contrasting views underpinning the different scenarios are reflected in divergent patterns of R&D investment between the private and public sectors. There appears to be a tension between the drive to transform energy systems, on the part of public bodies, mainly motivated by the need to combat global climate change, and private sector activity, which tends to reinforce and extend existing patterns of energy provision. The paper addresses, but not answer definitively, the key question as to whether technological change is enabling or frustrating ambitious carbon goals

The Effects of Research and Development Intensity on Managerial Compensation in Large Organizations

Agency theory, leading edge, and administrative life cycle perspectives all predict that organizations having high levels of Research and Development (R&D) intensity will follow different compensation strategies than organizations that are less R&D intensive. Using data from 110 organizations over a 5 year period, and controlling for organization differences in employee and job characteristics, we found support for this general prediction. Specifically, high R&D intensity organizations tended to have higher relative base pay, higher relative bonus pay, and greater relative eligibility for long-term incentive payments. We discuss the importance of further research into compensation decisions in R&D intensive firms, particularly the effects of such decisions on firms\u27 competitiveness

Determination of step rate thresholds corresponding to physical activity intensity classifications in adults

Current recommendations call for adults to be physically active at moderate and/or vigorous intensities. Given the popularity of walking and running, the use of step rates may provide a practical and inexpensive means to evaluate ambulatory intensity. Thus, the purpose of this study was to identify step rate thresholds that correspond to various intensity classifications. Methods: Oxygen consumption was measured at rest and during 10 minute treadmill walking and running trials at 6 standardized speeds (54, 80, 107, 134, 161, and 188 m∙min-1) in 9 men and 10 women (28.8 ± 6.8 yrs). Two observers counted the participants’ steps at each treadmill speed. Linear and nonlinear regression analyses were used to develop prediction equations to ascertain step rate thresholds at various intensities. Results: Nonlinear regression analysis of the metabolic cost versus step rates across all treadmill speeds yielded the highest R2 values for men (R2 = .91) and women (R2 = .79). For men, the nonlinear analysis yielded 94 and 125 step∙min-1 for moderate and vigorous intensities, respectively. For women, 99 and 135 step∙min-1 corresponded with moderate and vigorous intensities, respectively. Conclusions: Promoting a step rate of 100 step∙min-1 may serve as a practical public health recommendation to exercise at moderate intensity

Electron Capture Dissociation Mass Spectrometry of Metallo-Supramolecular Complexes

The electron capture dissociation (ECD) of metallo-supramolecular dinuclear triple-stranded helicate Fe2L3 4 ions was determined by Fourier transform ion cyclotron resonance mass spectrometry. Initial electron capture by the di-iron(II) triple helicate ions produces dinuclear double-stranded complexes analogous to those seen in solution with the monocationic metal centers CuI or AgI. The gas-phase fragmentation behavior [ECD, collision-induced dissociation (CID), and infrared multiphoton dissociation (IRMPD)] of the di-iron double-stranded complexes, (i.e., MS3 of the ECD product) was compared with the ECD, CID, and IRMPD of the CuI and AgI complexes generated from solution. The results suggest that iron-bound dimers may be of the formFeI 2L2 2 and that ECD by metallo-complexes allows access, in the gas phase,to oxidation states and coordination chemistry that cannot be accessed in solution

Conserved themes in small-RNA-mediated transposon control

Eukaryotes are engaged in a constant struggle against transposable elements, which have invaded and profoundly shaped their genomes. Over the past decade, a growing body of evidence has pointed to a role for small RNAs in transposon defense. Although the strategies used in different organisms vary in their details, they have strikingly similar general properties. Basically, all mechanisms consist of three components. First, transposon detection prompts the production of small RNAs, which are Piwi-interacting RNAs in some organisms and small interfering RNAs in others. Second, the population of small RNAs targeting active transposons is amplified through an RNA-dependent RNA polymerase-based or Slicer-based mechanism. Third, small RNAs are incorporated into Argonaute- or Piwi-containing effector complexes, which target transposon transcripts for post-transcriptional silencing and/or target transposon DNA for repressive chromatin modification and DNA methylation. These properties produce robust systems that limit the catastrophic consequences of transposon mobilization, which can result in the accumulation of deleterious mutations, changes in gene expression patterns, and conditions such as gonadal hypotrophy and sterility

Black and Latino Fathers of Students With Autism: Culturally Responsive Support

Perspectives from five Black and Latino fathers of students with autism are shared from this qualitative pilot study. The fathers were asked to describe the most helpful forms of support from school counselors. One-time, semi-structured interviews were conducted and interpreted with the thematic analysis method. Results suggest support from other parents, and specifically from other fathers, with shared experiences is most helpful. Recommendations for school counseling practice and research are shared

AlGaAs top solar cell for mechanical attachment in a multi-junction tandem concentrator solar cell stack

The AstroPower self-supporting, transparent AlGaAs top solar cell can be stacked upon any well-developed bottom solar cell for improved system performance. This is an approach to improve the performance and scale of space photovoltaic power systems. Mechanically stacked tandem solar cell concentrator systems based on the AlGaAs top concentrator solar cell can provide near term efficiencies of 36 percent (AMO, 100x). Possible tandem stack efficiencies greater than 38 percent (100x, AMO) are feasible with a careful selection of materials. In a three solar cell stack, system efficiencies exceed 41 percent (100x, AMO). These device results demonstrate a practical solution for a state-of-the-art top solar cell for attachment to an existing, well-developed solar cell

The global surge in energy innovation

Policymakers are seeking a transformation of the energy system driven by concerns about climate change, energy security and affordability. At the same time, emerging developments in underpinning science and engineering are opening up new possibilities across the whole technology spectrum covering renewables and other supply side technologies, energy demand and energy infrastructure. This paper reviews both the “policy pull” for energy innovation activities and the “science and technology push”. It explores the expectations of a variety of organisations in both the public and private sector regarding these pressures and possibilities by assessing various scenarios and outlook exercises that have been published since 2013. It reveals a wide range of beliefs about the future development of the energy system. The paper then moves on to analyse private sector expenditure on energy research and development (R&D) and public sector budgets for energy R&D and demonstration (RD&D). This analysis demonstrates significant divergences in patterns of innovation between the private and public sectors and leads to the hypothesis that the private sector is, broadly, taking measures to reinforce the existing energy paradigm while the public sector is focusing on new energy technologies that support wider policy objectives. This pattern is consistent with past technological transitions, with innovation efforts that would transform the energy system being counteracted by countervailing efforts that reinforce the existing fossil fuel-based paradigm

The Changing Face of Diabetes in Youth: Lessons Learned from Studies of Type 2 Diabetes

The incidence of youth type 2 diabetes (T2D), linked with obesity and declining physical activity in high-risk populations, is increasing. Recent multicenter studies have led to a number of advances in our understanding of the epidemiology, pathophysiology, diagnosis, treatment, and complications of this disease. As in adult T2D, youth T2D is associated with insulin resistance, together with progressive deterioration in β cell function and relative insulin deficiency in the absence of diabetes-related immune markers. In contrast to adult T2D, the decline in β cell function in youth T2D is three- to fourfold faster, and therapeutic failure rates are significantly higher in youth than in adults. Whether the more aggressive nature of youth T2D is driven by genetic heterogeneity or physiology/metabolic maladaptation is yet unknown. Besides metformin, the lack of approved pharmacotherapeutic agents for youth T2D that target the pathophysiological mechanisms is a major barrier to optimal diabetes management. There is a significant need for effective therapeutic options, in addition to increased prevention, to halt the projected fourfold increase in youth T2D by 2050 and the consequences of heightened diabetes-related morbidity and mortality at younger ages