13 research outputs found
Dihydropyridines’ metabolites-induced early apoptosis after myocardial infarction in rats; new outlook on preclinical study with M-2 and M-3
Effect of Prostacyclin on Fibrinolytic Activity in Patients with Arteriosclerosis Obliterans
and lipopolysaccharide-induced changes in nitric oxide, tumor necrosis factor-\alpha and vascular endothelial growth factor release from RAW 264.7 macrophages
Different response to fatty acids in metabolism and gene expression of human endothelial cells (HUVEC) and preadipocytes (SVF)
Recommended from our members
Gene-nutrient interactions on the phosphoenolpyruvate carboxykinase influence insulin sensitivity in metabolic syndrome subjects
Genetic background may interact with habitual dietary fat composition, and affect development of the metabolic syndrome (MetS). The phosphoenolpyruvate carboxykinase gene (PCK1) plays a significant role regulating glucose metabolism, and fatty acids are key metabolic regulators, which interact with transcription factors and influence glucose metabolism. We explored genetic variability at the PCK1 gene locus in relation to degree of insulin resistance and plasma fatty acid levels in MetS subjects. Moreover, we analyzed the PCK1 gene expression in the adipose tissue of a subgroup of MetS subjects according to the PCK1 genetic variants