Extraneural Sclerosing Perineurioma of the Buccal Mucosa: A Case Report and Clinicopathologic Review

The perineurioma is an infrequently encountered benign peripheral nerve sheath tumor composed of a clonal proliferation of perineurial cells. Rare cases of perineurioma have been reported in the oral cavity. An extraneural sclerosing perineurioma arising in the buccal mucosa of a 17-year-old male is presented. Histopathologically, the tumor is composed of a well circumscribed nodular proliferation of spindle cells arranged in a storiform growth pattern, in some areas subtly arranged around vascular channels. The tumor cells reveal positive immunostaining for epithelial membrane antigen (EMA), collagen type IV and vimentin, and negative immunostaining for S-100 protein, consistent with a perineurial origin. To the best of our knowledge, this case represents the first report of an extraneural sclerosing perineurioma involving the oral cavity

Shapes of love in the miracle testimonies of the Virgin of Chiquinquirá, New Kingdom of Granada, 1587 to 1694

A trilogy of texts composed between 1587 and 1694 memorialize the origin of and early devotion to the Virgin of Chiquinquirá in the New Kingdom of Granada: an información jurídica (original ecclesiastical investigation of reported miracles ordered by the archbishop of Bogotá); a manuscript collection of 234 miracle testimonies, long-lost and never studied until now; and the first published history of the cult. The devotees whose experiences comprise these texts had turned to Mary of Chiquinquirá with deeply personal needs and received miraculous interventions. Later, they recounted their experiences under oath before witnesses. This essay examines those accounts, finding vestiges of local society and culture and, more importantly, illumination of the testators\u27 enacted feelings about themselves and others. The essay argues that within the intimate space of a spiritual emotional community, miracle testimonies which purport to focus on love for the Virgin of Chiquinquirá actually reveal a great deal about human love