The influence of the copper content in grape must on alcoholic fermentation kinetics and wine quality. A survey on the performance of 50 commercial Active Dry Yeasts

The effects of copper on the viability and fermentative activity of 50 active dry yeasts purchased on the northern Italian market were studied, and revealed that Copper excess may cause massive death of yeast cells, leading to a significant delay in the start and progress of alcoholic fermentation. A two-log units reduction in cell viability was observed when copper content of musts was around 20 mg∙L-1. Despite this, the difference noted in the kinetics after 20 days' fermentation was lower than that observed 48 hours after in the grape must. An excess of copper in must affected also the composition of the produced wines. The increase in acetic acid and in the sulphur dioxide concentration, observed in wines made using grape must with a high copper concentration, raises serious doubts both regarding the possibility of obtaining good wines from these raw materials and in relation to the progress of subsequent steps of winemaking, such as malolactic fermentation. While it is an important tool in preventing vine diseases, copper must be used very carefully to avoid serious troubles during wine fermentation, even if some yeasts seem more suited to ferment musts containing up to 20-30 mg∙L-1 copper.

Relapsing bronchiolitis obliterans organising pneumonia and chronic sarcoidosis in an atopic asthmatic patient

Asthma is thought to be a Th2 disease while sarcoidosis is considered a Th1 granulomatous disorder. Organising pneumonia is a histologic pattern of lung injury. When it has no recognisable cause it is defined as cryptogenic organising pneumonia. We herein report the case of a patient with recurrent and steroid sensitive organising pneumonia associated with chronic sarcoidosis in an atopic, moderate persistent asthmatic patient. Each disease has been documented with transbronchial biopsies and recurrence of organising pneumonia was suggested by clinical features and by follow up HRCT which shows distinctive signs even in associated disease. Steroids are the mainstay of therapy for these disorders and especially for the consolidated processes typical of organising pneumonia but prognostic indices for relapse and progression are lacking

Histopathology of vasculitis

The range of pathologies that are related to primitive vasculitis is broad, complex and not as typical as we would expect. Clinicians should be aware that several forms of primitive and systemic vasculitis, regardless of the size of the affected vessel, may exhibit identical histological alterations. This observation has important clinical implications as it means that cases of vasculitis do not correspond clinically and histologically. Thus, while histology remains the diagnostic gold standard, it can be used only as part of the most complete clinical assessment possible. Another point worth of the clinician’s attention is that vasculitis histology changes over time, as do disease evolution and activity, even without considering the masking effects of treatment and the possibility of sampling error due to the patchy occurrence of vasculitis. The purpose of this review is to identify the most common forms of vasculitis in clinical practice, and to provide guidance to the clinician on the pathology of the vessels

When a Politician Disappoints: The Role of Gender Stereotypical Expectations in Post-Scandal Judgment

This study examines how evaluations of male and female politicians are worsened by corruption scandals that disappoint expectations of honesty. Participants evaluated a fictitious politician before and after watching a video about a corruption scandal involving that politician. The manipulated variables were the politician’s sex and whether they shared participants’ political affiliations. Results showed that a female politician affiliated with the participants’ preferred party was the most damaged by the scandal because she had the highest expectations of honesty placed upon her

Photocatalytic hydrogen production using polymeric carbon nitride with a hydrogenase and a bioinspired synthetic Ni catalyst.

Solar-light-driven H2 production in water with a [NiFeSe]-hydrogenase (H2ase) and a bioinspired synthetic nickel catalyst (NiP) in combination with a heptazine carbon nitride polymer, melon (CN(x)), is reported. The semibiological and purely synthetic systems show catalytic activity during solar light irradiation with turnover numbers (TONs) of more than 50,000 mol H2(mol H2ase)(-1) and approximately 155 mol H2 (mol NiP)(-1) in redox-mediator-free aqueous solution at pH 6 and 4.5, respectively. Both systems maintained a reduced photoactivity under UV-free solar light irradiation (λ>420 nm).This is the final version. It was first published in Angewandte Chemie International Edition at http://onlinelibrary.wiley.com/doi/10.1002/anie.201406811/abstract