240 research outputs found
Making drug delivery in the ICU safer: the implementation of advanced computerised intravenous infusion pumps
Algae as nutritional and functional food sources: revisiting our understanding.
Global demand for macroalgal and microalgal foods is growing, and algae are increasingly being consumed for functional benefits beyond the traditional considerations of nutrition and health. There is substantial evidence for the health benefits of algal-derived food products, but there remain considerable challenges in quantifying these benefits, as well as possible adverse effects. First, there is a limited understanding of nutritional composition across algal species, geographical regions, and seasons, all of which can substantially affect their dietary value. The second issue is quantifying which fractions of algal foods are bioavailable to humans, and which factors influence how food constituents are released, ranging from food preparation through genetic differentiation in the gut microbiome. Third is understanding how algal nutritional and functional constituents interact in human metabolism. Superimposed considerations are the effects of harvesting, storage, and food processing techniques that can dramatically influence the potential nutritive value of algal-derived foods. We highlight this rapidly advancing area of algal science with a particular focus on the key research required to assess better the health benefits of an alga or algal product. There are rich opportunities for phycologists in this emerging field, requiring exciting new experimental and collaborative approaches.AGS & KEH thank the Biotechnology and Biological Sciences Research Council (BBSRC BB/1013164/1) of the UK for funding. The University of Dundee is a registered Scottish charity, No. SC015096. PP is supported by IDEALG in the frame of the stimuli program entitled “Investissements d’avenir, Biotechnologies-Bioressources” (ANR-10-BTBR-04-02). The open access fee was supported by NSF-OCE-1435021 (MLW), DIC project 1823-06 (MEC), Maine Sea Grant (NOAA) 5405971 (SHB), NSF #11A-1355457 to Maine EPSCoR at the University of Maine (SHB), and the listed funding to AGS and PP
Algae as nutritional and functional food sources: revisiting our understanding.
Global demand for macroalgal and microalgal foods is growing, and algae are increasingly being consumed for functional benefits beyond the traditional considerations of nutrition and health. There is substantial evidence for the health benefits of algal-derived food products, but there remain considerable challenges in quantifying these benefits, as well as possible adverse effects. First, there is a limited understanding of nutritional composition across algal species, geographical regions, and seasons, all of which can substantially affect their dietary value. The second issue is quantifying which fractions of algal foods are bioavailable to humans, and which factors influence how food constituents are released, ranging from food preparation through genetic differentiation in the gut microbiome. Third is understanding how algal nutritional and functional constituents interact in human metabolism. Superimposed considerations are the effects of harvesting, storage, and food processing techniques that can dramatically influence the potential nutritive value of algal-derived foods. We highlight this rapidly advancing area of algal science with a particular focus on the key research required to assess better the health benefits of an alga or algal product. There are rich opportunities for phycologists in this emerging field, requiring exciting new experimental and collaborative approaches.AGS & KEH thank the Biotechnology and Biological Sciences Research Council (BBSRC BB/1013164/1) of the UK for funding. The University of Dundee is a registered Scottish charity, No. SC015096. PP is supported by IDEALG in the frame of the stimuli program entitled “Investissements d’avenir, Biotechnologies-Bioressources” (ANR-10-BTBR-04-02). The open access fee was supported by NSF-OCE-1435021 (MLW), DIC project 1823-06 (MEC), Maine Sea Grant (NOAA) 5405971 (SHB), NSF #11A-1355457 to Maine EPSCoR at the University of Maine (SHB), and the listed funding to AGS and PP
1997 Wild Blueberry Progress Reports
The 1997 edition of the Wild Blueberry Progress Reports was prepared for the Wild Blueberry Commission of Maine and the Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Investigation of processing damage of IQF blueberries
2. Use of sorter rejects and wild blueberry puree to prevent warmed over flavor in processed beef patties
3. Factors affecting the quality of IQF wild blueberries
4. Determination of pesticide residue levels in fresh and processed wild blueberries
5. Pollination ecology of wild blueberries in Maine
6. Control tactics for wild blueberry pest insects
7. IPM Strategies
8. Pest Biology
9. Effect of antidessication treatments on wild blueberry cold temperature tolerance
10. Phosphorus/nitrogen fertilizer ratio
11. Effect of boron application methods on boron uptake in wild blueberries
12. Effect of foliar zinc application on growth and yield of wild blueberries
13. Effect of soil pH on nutrient uptake
14. Crop year fertilization of wild blueberry
15. Effect of Photomag® on growth and yield of wild blueberries
16. Evaluation of Pronone MG® spot treatments for control of St. Johnswort, dogbane, bracken fern, witch grass/fall panicum and bunchberry
17. Effect of hexazinone formulation on movement through the soil profile
18. Effect of time of fall pruning on wild blueberry fruit set and yield
19. Effect of pre and postemergence herbicide applications on control of grasses
20. Hexazinone groundwater survey
21. Effect of plant source and density on spread of wild blueberry
22. Effect of surfactant and ammonium sulfate on glyphosate activity
23. Effect of crop year application of hexazinone on weed control, yield and hexazinone residue.
24. Long term effects of tribenuron methyl on wild blueberries and weed species composition
25. Effect of Velpar® DF/MAP on wild blueberry fruit set and yield.
26. Effect of reduced volume lmidan® 2.5 EC UL V applications on wild blueberry residue and efficacy
27. Wild blueberry extension education progra
1998 CSREES Wild Blueberry Project Results
The 1998 edition of the CSREES Wild Blueberry Project Results was prepared for the Maine Blueberry Commission and the University of Maine Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Separation of Maggot Infested Blueberries in the IQF Processing Line
2. Assessment of Preharvest Treatments on Wild blueberry Fruit Quality
3. Blueberries as a Natural Colorant for Breakfast Cereals
4. Factors Affecting Quality of IQF Wild Blueberries
5. Control Tactics for Wild blueberry Pest Insects
6. Biology and Ecology of Wild blueberry Pest Insects
7. Sustainable Pollination of Wild blueberry
8. Evaluation of Foliar Fungicides for Control of Mummy Berry
9. Phosphorus/Nitrogen Fertilizer Ratio
10. Effect of Boron Application Methods on Boron Uptake in Wild Blueberries
11. Effect of Zinc Application on Growth and Yield of Wild Blueberries
12. Effect of Soil pH of Nutrient Uptake
13. Crop Year Fertilization of Wild blueberry
14. Effect of Fertilizer Timing on Wild blueberry Growth and Productivity
15. Alternative Methods of Grass Control
16. Cultural Weed Management Using pH
17. Investigation of Hexazinone Alternatives for Weed Control
18. Evaluation of Hexazinone Applications in the Cropping Year
19. Effect of Surfactant and Ammonium Sulfate on Glyphosate Activity
20. Evaluation of Pronone MG® Spot Treatments for Control of St Jobnswort, Dogbane, Bracken Fem, Witch Grass/Fall Panicum and Bunchberry
21. Hexazinone Groundwater Surve
1996 Wild Blueberry CSREES Progress Reports/1996 Wild Blueberry Tax Reports
The 1996 edition of the Wild Blueberry CSREES Progress Reports/Wild Blueberry Tax Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
Wild Blueberry CSREES Progress Reports:
1. Factors affecting the quality of Individually Quick Frozen (IQF) wild blueberries
2. Factors affecting the physical and chemical properties of IQF wild blueberries
3. Preventing the bleeding of blueberry fruit in bakery products
4. Amylase test development
5. Determination of pesticide residue levels in freshly harvested and processed wild blueberries
6. Sustainable pollination of wild blueberry
7. Potential for biological control of insect pests of wild blueberry
8. Effect of desiccation on wild blueberry winter survival and cold temperature tolerance
9. Population variation in low-temperature tolerance of wild blueberry
10. Influence of flower delaying sprays on seasonal variation of low temperature tolerance in wild blueberry
11. Effect of various levels of disbudding on yield of wild blueberry
12. Effect of boron and the polyamine putrescine on wild blueberry fruit set and yield
13. Effect of soil pH on nutrient uptake
14. Phosphorus uptake
15. Correcting boron deficiency
16. Hexazinone groundwater survey
17. Effect of time of fall pruning on growth and productivity of wild blueberries
18. Evaluation of Pronone® spot treatments for control of St. Johnswort, dogbane, bracken fern, witch grass/fall panicum and bunchberry
19. Effect of hexazinone formulation on movement through the soil profile
20. Effect of plant source and density on spread of wild blueberry
Wild Blueberry Tax Reports:
21. Control of wild blueberry diseases
22. Control of wild blueberry pest insects
23. Biology and action thresholds of secondary blueberry pest insects
24. Phosphorus/nitrogen fertilizer ratio
25. Effect of surfactant and ammonium sulfate on glyphosate activity
26. Blueberry Extension Education Program Bas
2002 Wild Blueberry Project Reports
The 2002 edition of the Wild Blueberry Project Reports was prepared for the Wild Blueberry Commission of Maine and the Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Factors Affecting Microbial and Pesticide Residue Levels on Wild Blueberries
2. Effect of Blueberry Products on Oxidation in Meat Based Food
3. Determination of Pesticide Residue Levels in Freshly Harvested and Processed Wild Blueberries
4. Detection of Infested Wild Blueberries using Near-Infrared Spectroscopy
5. Investigation Of The Mechanism By Which Blueberry Fractions Maintain Arterial Integrity
6. Antioxidant Assessment in the Elderly
7. Water Use of Wild Blueberries and the Impact of Plant Water Stress on Yield
8. Control Tactics for Wild blueberry Pest Insects
9. IPM Strategies
10. Pest Biology
11. Wild Blueberry Pollination Research
12. Survey and Determination of Effective Control of Stem Blight and Leaf Spot Diseases in Wild Blueberry Fields
13. Effect of Foliar-applied Iron Chelate Concentration on Leaf Iron Concentration, Wild Blueberry Growth and Yield
14. Effect of Boron Application Methods on Boron Uptake in Wild Blueberries
15. Effect of Foliar N spray on Leaf N Concentration, Growth and Yield of Wild Blueberries
16. Effect of Foliar Spray (4-13-15) on Leaf Nutrient Concentration, Growth and Yield of Wild Blueberries
17. Effect of Foliar Copper Application on Growth and Yield of Wild Blueberries
18. Effect of Foliar Copper and/or Iron Application on Growth and Yield of Wild Blueberries
19. Effect of Soil pH on Nutrient Uptake
20. Assessment of Hexazinone Alternatives for Weed Control in Wild Blueberries and Weed Control
21. Evaluation of Fall Applications of Sulfonylurea Herbicides for Bunchberry Control in Wild Blueberries
22. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields
23. Blueberry Extension Education Program Base
24. 2002 Pesticide Groundwater Survey
25. Cultural Weed Management using sulfur to lower the p
1995 CSREES Reports
The 1995 edition of the CSREES Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Factors Affecting the Quality of IQF Blueberries
2. Preventing the Bleeding of Blueberry Fruit in Bakery Products
3. Removing Water from Blueberries Before Freezing
4. Determination of Pesticide Residue Levels in Freshly Harvested and Processed Lowbush Blueberries
5. Industrial Ingredients from Cull Blueberries
6. Application of Heat as a Method of Controlling Secondary Pest Insects on Lowbush Blueberries
7. The Phenology and Biology of Bumble Bees, Bombus, spp., that Pollinate Lowbush blueberry, Vaccinium spp., in Maine
8. Pollination Ecology of Lowbush Blueberry in Maine
9. Effects of Irrigation on Lowbush Blueberry Yield
10. Effect of Brief Warming Treatments on Late Winter Low-Temperature Tolerance of Native Lowbush Blueberry
11. Correlation of Late-winter/Early-spring Cold Hardiness with Date of Flowering
12. Evaluation of Cold Tolerance of Opening Flowers of Lowbush Blueberry
13. Influence of Flower Delaying Sprays on Seasonal Variation of Low Temperature Tolerance in Lowbush Blueberry
14. Effect of Various Levels of Disbudding on Yield of Lowbush Blueberry
15. Effect of Boron and the Polyamine Putrescine on Lowbush Blueberry Fruit Set and Yield
16. Effect of Boron and the Polyamine Putrescine on Extending the Receptivity of Lowbush Blueberry Blossoms
17. Effect of Soil pH on Nutrient Uptake
18. Correcting Boron Deficiency - missing
19. Phosphorus Uptake
20. Evaluation of Hexazinone Formulation on Soil Movement and Weed Control
21. Effect of Time of Fall Pruning on Growth and Productivity of Blueberries
22. Hexazinone Ground Water Survey
23. Effect of hexazinone formulation on movement through the soil profile
24. Evaluation of Tribenuron Methyl for Bunchberry Control
25. Evaluation of Tribenuron Methyl Commercial Applications for Bunchberry Control
26. Effectiveness of Resin-Exchange Columns to Determine Efficacy in Removing Hexazinone from Well Water
27. Effect of Clopyralid for Vetch Control
28. Evaluation of Tribenuron Methyl/Velpar® Tank Mix for Bunchberry Control
29. Blueberry Extension Education Progra
Endocytosis of plasma-derived factor V by megakaryocytes occurs via a clathrin-dependent, specific membrane binding event
Megakaryocytes were analyzed for their ability to endocytose factor V to define the cellular mechanisms regulating this process. In contrast to fibrinogen, factor V was endocytosed by megakaryocytes derived from CD34 + cells or megakaryocyte-like cell lines, but not by platelets. CD41 + ex vivo -derived megakaryocytes endocytosed factor V, as did subpopulations of the megakaryocyte-like cells MEG-01, and CMK. Similar observations were made for fibrinogen. Phorbol diester-induced megakaryocytic differentiation of the cell lines resulted in a substantial increase in endocytosis of both proteins as compared to untreated cells that did not merely reflect their disparate plasma concentrations. Factor IX, which does not associate with platelets or megakaryocytes, was not endocytosed by any of the cells examined. Endocytosis of factor V by megakaryocytes proceeds through a specific and independent mechanism as CHRF-288 cells endocytosed fibrinogen but not factor V, and the presence of other plasma proteins had no effect on the endocytosis of factor V by MEG-01 cells. Furthermore, as the endocytosis of factor V was also demonstrated to occur through a clathrin-dependent mechanism, these combined data demonstrate that endocytosis of factor V by megakaryocytes occurs via a specific, independent, and most probably receptor-mediated, event.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75473/1/j.1538-7836.2005.01190.x.pd
2000 Wild Blueberry Project Reports
The 2000 edition of the Wild Blueberry Project Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Determination of Pesticide Residue Levels in Fresh and Processed Wild Blueberries
2. Factors Affecting the Microbiological Quality of IQF Blueberries
3. Effect of Processed Blueberry Products on Oxidation in Meat Based Food Systems
4. Separation of Maggot Infested Wild Blueberries in the IQF Processing Line
5. Water Use of Wild Blueberries
6. Control Tactics for Blueberry Pest Insects, 2000
7. IPM Strategies
8. Biology and Ecology of Blueberry Pest Insects
9. Survey of Stem Blight and Leaf Spot Diseases in Lowbush Blueberry Fields
10. Phosphorus/Nitrogen Fertilizer Ratio
11. Effect of Boron Application Methods on Boron Uptake in Lowbush Blueberries
12. Effect of Foliar Iron and Copper Application on Growth and Yield of Lowbush Blueberries
13. Effect of Soil pH on Nutrient Uptake
14. Effect of Nutri-Phite (tm) P+K on Growth and Yield of Lowbush Blueberry
15. Effect of Fertilizer Timing on Lowbush Blueberry Growth and Productivity
16. Assessment of Azafenidin for Weed Control in Wild Blueberries
17. Assessment of Rimsulfuron for Weed Control in Wild Blueberries
18. Assessment of Pendimethalin for Weed Control in Wild Blueberries
19. Assessment of VC1447 for Weed Control in Wild Blueberries
20. Cultural Management Using pH for Weed Control in Wild Blueberries
21. Evaluation of Sprout-Less Weeder® for Weed Control in Wild Blueberries
22. Evaluation of RoundUp Ultra® and Touchdown 5® for Weed Control in Wild Blueberries
23. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields
24. Evaluation of Fungicides Efficacy in Wild Blueberry Fields
25. Velpar® and Sinbar/Karmex® Demonstration Plot Comparison Trial
26. Blueberry Extension Education Program in 2000
27. 2000 Hexazinone Groundwater Surve
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