1,045 research outputs found

    Cyber System Assurance through Improved Network Anomaly Modeling and Detection

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    NPS NRP Project PosterCyber System Assurance through Improved Network Anomaly Modeling and DetectionN8 - Integration of Capabilities & ResourcesThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations (CNO)Approved for public release. Distribution is unlimited.

    Cyber System Assurance through Improved Network Anomaly Modeling and Detection

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    NPS NRP Technical ReportCyber System Assurance through Improved Network Anomaly Modeling and DetectionN8 - Integration of Capabilities & ResourcesThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations (CNO)Approved for public release. Distribution is unlimited.

    Cyber System Assurance through Improved Network Anomaly Modeling and Detection

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    NPS NRP Executive SummaryCyber System Assurance through Improved Network Anomaly Modeling and DetectionN8 - Integration of Capabilities & ResourcesThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations (CNO)Approved for public release. Distribution is unlimited.

    Multiple CSLs for the body centered cubic lattice

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    Ordinary Coincidence Site Lattices (CSLs) are defined as the intersection of a lattice Γ\Gamma with a rotated copy RΓR\Gamma of itself. They are useful for classifying grain boundaries and have been studied extensively since the mid sixties. Recently the interests turned to so-called multiple CSLs, i.e. intersections of nn rotated copies of a given lattice Γ\Gamma, in particular in connection with lattice quantizers. Here we consider multiple CSLs for the 3-dimensional body centered cubic lattice. We discuss the spectrum of coincidence indices and their multiplicity, in particular we show that the latter is a multiplicative function and give an explicit expression of it for some special cases.Comment: 4 pages, SSPCM (31 August - 7 September 2005, Myczkowce, Poland

    Imaging Pulsed Laser Deposition oxide growth by in-situ Atomic Force Microscopy

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    To visualize the topography of thin oxide films during growth, thereby enabling to study its growth behavior quasi real-time, we have designed and integrated an atomic force microscope (AFM) in a pulsed laser deposition (PLD) vacuum setup. The AFM scanner and PLD target are integrated in a single support frame, combined with a fast sample transfer method, such that in-situ microscopy can be utilized after subsequent deposition pulses. The in-situ microscope can be operated from room temperature (RT) up to 700^\circC and at (process) pressures ranging from the vacuum base pressure of 106^{-6} mbar up to 1 mbar, typical PLD conditions for the growth of oxide films. The performance of this instrument is demonstrated by resolving unit cell height surface steps and surface topography under typical oxide PLD growth conditions.Comment: 8 pages, 8 figure

    Coincidences in 4 dimensions

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    The coincidence site lattices (CSLs) of prominent 4-dimensional lattices are considered. CSLs in 3 dimensions have been used for decades to describe grain boundaries in crystals. Quasicrystals suggest to also look at CSLs in dimensions d>3d>3. Here, we discuss the CSLs of the root lattice A4A_4 and the hypercubic lattices, which are of particular interest both from the mathematical and the crystallographic viewpoint. Quaternion algebras are used to derive their coincidence rotations and the CSLs. We make use of the fact that the CSLs can be linked to certain ideals and compute their indices, their multiplicities and encapsulate all this in generating functions in terms of Dirichlet series. In addition, we sketch how these results can be generalised for 4--dimensional Z\Z--modules by discussing the icosian ring.Comment: 6 pages, conference "Quasicrystals - The Silver Jubilee

    Determining the energetics of vicinal perovskite oxide surfaces

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    The energetics of vicinal SrTiO3_3(001) and DyScO3_3(110), prototypical perovskite vicinal surfaces, has been studied using topographic atomic force microscopy imaging. The kink formation and strain relaxation energies are extracted from a statistical analysis of the step meandering. Both perovskite surfaces have very similar kink formation energies and exhibit a similar triangular step undulation. Our experiments suggest that the energetics of perovskite oxide surfaces is mainly governed by the local oxygen coordination.Comment: 16 pages, 4 figure

    Characterization of an Immobilized Amino Acid Racemase for Potential Application in Enantioselective Chromatographic Resolution Processes

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    Enantioselective resolution processes can be improved by integration of racemization. Applying environmentally friendly enzymatic racemization under mild conditions is in particular attractive. Owing to the variety of enzymes and the progress in enzyme engineering, suitable racemases can be found for many chiral systems. An amino acid racemase (AAR) from P. putida KT2440 is capable of processing a broad spectrum of amino acids at fast conversion rates. The focus of this study is the evaluation of the potential of integrating AAR immobilized on Purolite ECR 8309 to racemize L- or D-methionine (Met) within an enantioselective chromatographic resolution process. Racemization rates were studied for different temperatures, pH values, and fractions of organic co-solvents. The long-term stability of the immobilized enzyme at operating and storage conditions was found to be excellent and recyclability using water with up to 5 vol% ethanol at 20 °C could be demonstrated. Packed as an enzymatic fixed bed reactor, the immobilized AAR can be coupled with different resolution processes; for instance, with chromatography or with preferential crystallization. The performance of coupling it with enantioselective chromatography is estimated quantitatively, exploiting parametrized sub-models. To indicate the large potential of the AAR, racemization rates are finally given for lysine, arginine, serine, glutamine, and asparagine

    Development of an international standard set of outcome measures for patients with atrial fibrillation: a report of the International Consortium for Health Outcomes Measurement (ICHOM) atrial fibrillation working group.

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    AIMS: As health systems around the world increasingly look to measure and improve the value of care that they provide to patients, being able to measure the outcomes that matter most to patients is vital. To support the shift towards value-based health care in atrial fibrillation (AF), the International Consortium for Health Outcomes Measurement (ICHOM) assembled an international Working Group (WG) of 30 volunteers, including health professionals and patient representatives to develop a standardized minimum set of outcomes for benchmarking care delivery in clinical settings. METHODS AND RESULTS: Using an online-modified Delphi process, outcomes important to patients and health professionals were selected and categorized into (i) long-term consequences of disease outcomes, (ii) complications of treatment outcomes, and (iii) patient-reported outcomes. The WG identified demographic and clinical variables for use as case-mix risk adjusters. These included baseline demographics, comorbidities, cognitive function, date of diagnosis, disease duration, medications prescribed and AF procedures, as well as smoking, body mass index (BMI), alcohol intake, and physical activity. Where appropriate, and for ease of implementation, standardization of outcomes and case-mix variables was achieved using ICD codes. The standard set underwent an open review process in which over 80% of patients surveyed agreed with the outcomes captured by the standard set. CONCLUSION: Implementation of these consensus recommendations could help institutions to monitor, compare and improve the quality and delivery of chronic AF care. Their consistent definition and collection, using ICD codes where applicable, could also broaden the implementation of more patient-centric clinical outcomes research in AF

    Distinct crustal structure of the North American Midcontinent Rift from P wave receiver functions

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    Eighty-two broadband seismic stations of the Superior Province Rifting Earthscope Experiment (SPREE) collected 2.5 years of continuous seismic data in the area of the high gravity anomaly associated with the Midcontinent Rift (MCR). Over 100 high-quality teleseismic earthquakes were used for crustal P wave receiver function analysis. Our analysis reveals that the base of the sedimentary layer is shallow outside the MCR, thickens near the flanks where gravity anomalies are low, and shallows again in the MCR's center where the gravity anomalies peak. This pattern is similar to that found from local geophysical studies and is consistent with reverse faulting having accompanied the cessation of rifting at 1.1 Ga. Intermittent intracrustal boundaries imaged by our analysis might represent the bottom of the MCR's mostly buried dense volcanic layers. Outside the MCR, the Moho is strong, sharp, and relatively flat, both beneath the Archean Superior Province and the Proterozoic terranes to its south. Inside the MCR, two weaker candidate Mohos are found at depths up to 25 km apart in the rift's center. The intermediate layer between these discontinuities tapers toward the edges of the MCR. The presence of this transitional layer is remarkably consistent along the strike of the MCR, including beneath its jog in southern Minnesota, near the Belle Plaine Fault. We interpret these results as evidence for extensive underplating as a defining characteristic of the rift, which remains continuous along the Minnesota jog, where due to its orientation, it is minimally affected by the reverse faulting that characterizes the NNE striking parts of the rift
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