Probabilistic reasoning with a bayesian DNA device based on strand displacement

We present a computing model based on the DNA strand displacement technique which performs Bayesian inference. The model will take single stranded DNA as input data, representing the presence or absence of a specific molecular signal (evidence). The program logic encodes the prior probability of a disease and the conditional probability of a signal given the disease playing with a set of different DNA complexes and their ratios. When the input and program molecules interact, they release a different pair of single stranded DNA species whose relative proportion represents the application of Bayes? Law: the conditional probability of the disease given the signal. The models presented in this paper can empower the application of probabilistic reasoning in genetic diagnosis in vitro

Survey on Vision-based Path Prediction

Path prediction is a fundamental task for estimating how pedestrians or vehicles are going to move in a scene. Because path prediction as a task of computer vision uses video as input, various information used for prediction, such as the environment surrounding the target and the internal state of the target, need to be estimated from the video in addition to predicting paths. Many prediction approaches that include understanding the environment and the internal state have been proposed. In this survey, we systematically summarize methods of path prediction that take video as input and and extract features from the video. Moreover, we introduce datasets used to evaluate path prediction methods quantitatively.Comment: DAPI 201

Probing nuclear expansion dynamics with π−/π+\pi^-/\pi^+-spectra

We study the dynamics of charged pions in the nuclear medium via the ratio of differential $\pi^-$- and $\pi^+$-spectra in a coupled-channel BUU (CBUU) approach. The relative energy shift of the charged pions is found to correlate with the pion freeze-out time in nucleus-nucleus collisions as well as with the impact parameter of the heavy-ion reaction. Furthermore, the long-range Coulomb force provides a 'clock' for the expansion of the hot nuclear system. Detailed comparisons with experimental data for $Au + Au$ at 1 GeV/A and $Ni + Ni$ at 2.0 GeV/A are presented.Comment: 21 pages, latex, figures include

Dynamics of Transformation from Segregation to Mixed Wealth Cities

We model the dynamics of the Schelling model for agents described simply by a continuously distributed variable - wealth. Agents move to neighborhoods where their wealth is not lesser than that of some proportion of their neighbors, the threshold level. As in the case of the classic Schelling model where segregation obtains between two races, we find here that wealth-based segregation occurs and persists. However, introducing uncertainty into the decision to move - that is, with some probability, if agents are allowed to move even though the threshold level condition is contravened - we find that even for small proportions of such disallowed moves, the dynamics no longer yield segregation but instead sharply transition into a persistent mixed wealth distribution. We investigate the nature of this sharp transformation between segregated and mixed states, and find that it is because of a non-linear relationship between allowed moves and disallowed moves. For small increases in disallowed moves, there is a rapid corresponding increase in allowed moves, but this tapers off as the fraction of disallowed moves increase further and finally settles at a stable value, remaining invariant to any further increase in disallowed moves. It is the overall effect of the dynamics in the initial region (with small numbers of disallowed moves) that shifts the system away from a state of segregation rapidly to a mixed wealth state. The contravention of the tolerance condition could be interpreted as public policy interventions like minimal levels of social housing or housing benefit transfers to poorer households. Our finding therefore suggests that it might require only very limited levels of such public intervention - just sufficient to enable a small fraction of disallowed moves, because the dynamics generated by such moves could spur the transformation from a segregated to mixed equilibrium.Comment: 12 pages, 7 figure

Towards a Statistical Physics of Human Mobility

In this paper, we extend some ideas of statistical physics to describe the properties of human mobility. From a physical point of view, we consider the statistical empirical laws of private cars mobility, taking advantage of a GPS database which contains a sampling of the individual trajectories of 2% of the whole vehicle population in an Italian region. Our aim is to discover possible "universal laws" that can be related to the dynamical cognitive features of individuals. Analyzing the empirical trip length distribution we study if the travel time can be used as universal cost function in a mesoscopic model of mobility. We discuss the implications of the elapsed times distribution between successive trips that shows an underlying Benford's law, and we study the rank distribution of the average visitation frequency to understand how people organize their daily agenda. We also propose simple stochastic models to suggest possible explanations of the empirical observations and we compare our results with analogous results on statistical properties of human mobility presented in the literature