Constant of Motion for several one-dimensional systems and outlining the problem associated with getting their Hamiltonians

The constants of motion of the following systems are deduced: a relativistic particle with linear dissipation, a no-relativistic particle with a time explicitly depending force, a no-relativistic particle with a constant force and time depending mass, and a relativistic particle under a conservative force with position depending mass. The problem of getting the Hamiltonian for these systems is determined by getting the velocity as an explicit function of position and generalized linear momentum, and this problem can be solved a first approximation for the first above system.Comment: 15 pages, Te

INFLUENCE OF CERIUM ADDITION ON THE SYNTHESIS OF SOLIDS BASED ON PLATINUM SUPPORTED OVER ALUMINA-PILLARED CLAY

The present work shows the preparation and characterization of a set of solids by modification of a natural clay with Al, Ce and Pt. The characterization of the solids by X-ray diffraction (XRD) reveals the insertion of alumina pillars, whereas the subsequent impregnations of the pillared clay with Pt (II) or Ce (IV) do not lead to structural variations that can be observed by XRD. The characterization by nitrogen adsorption indicates that the incorporation of platinum species originates damages in the microporosity of the solid, while the addition of cerium prevents the deterioration of the textural propertie

Resiliencia de la biodiversidad natural frente a las prácticas de manejo en sistemas productivos de aguacate

Las labores antrópicas sobre los sistemas productivos ocasionan deterioros ambientales y perdidas de la capacidad de los sistemas para enfrentar perturbaciones externas, pero la biodiversidad se presenta como estrategia para mitigar estos efectos y generar resistencia en pro de la eficiencia del sistema, por tanto, el objetivo de este trabajo fue evaluar la resiliencia de las biodiversidad en plantas acompañantes, frente a las prácticas de manejo en sistemas productivos de aguacate en la Cuenca del Rio Negro de Antioquia – Colombia. Se encontró que los sistemas productivos de aguacate, presenta alta diversidad de plantas acompañantes reportando valores de Shannon de 2.26 para el manejo mecánico (MM) y 2.69 para manejos mixtos (MMx), mientras que el índice de Simpson, los valores medios encontrados fueron 0.85 para las MM y 0.87 para los MMx. Lo que sugiere una condición de resiliencia natural propia para los sistemas productivos aguacateros de la cuenca.The anthropic labors on the productive systems they cause deteriorations environmental and losses of the capacity of the systems to face external disturbances, but the biodiversity appears as strategy to mitigate these effects and to generate resistance in favor of the efficiency of the system, therefore, the objective of this study was to evaluate the resilience of biodiversity in companion planting, versus management practices in avocado production systems in the Black River basin of Antioquia - Colombia.. It was found that the productive systems of avocado, he presents high diversity of plants accompanists bringing values of Shannon of 2.26 for the mechanical managing (MM) and 2.69 for mixed managing (MMx), whereas Simpson's index, the average opposing values were 0.85 for the MM and 0.87 for the MMx. What native suggests a condition of resilience own for the productive in avocado systems of the basin.Eje A1 Sistemas de producción de base agroecológica (Trabajos científicos)Facultad de Ciencias Agrarias y Forestale

Resiliencia de la biodiversidad natural frente a las prácticas de manejo en sistemas productivos de aguacate

Las labores antrópicas sobre los sistemas productivos ocasionan deterioros ambientales y perdidas de la capacidad de los sistemas para enfrentar perturbaciones externas, pero la biodiversidad se presenta como estrategia para mitigar estos efectos y generar resistencia en pro de la eficiencia del sistema, por tanto, el objetivo de este trabajo fue evaluar la resiliencia de las biodiversidad en plantas acompañantes, frente a las prácticas de manejo en sistemas productivos de aguacate en la Cuenca del Rio Negro de Antioquia – Colombia. Se encontró que los sistemas productivos de aguacate, presenta alta diversidad de plantas acompañantes reportando valores de Shannon de 2.26 para el manejo mecánico (MM) y 2.69 para manejos mixtos (MMx), mientras que el índice de Simpson, los valores medios encontrados fueron 0.85 para las MM y 0.87 para los MMx. Lo que sugiere una condición de resiliencia natural propia para los sistemas productivos aguacateros de la cuenca.The anthropic labors on the productive systems they cause deteriorations environmental and losses of the capacity of the systems to face external disturbances, but the biodiversity appears as strategy to mitigate these effects and to generate resistance in favor of the efficiency of the system, therefore, the objective of this study was to evaluate the resilience of biodiversity in companion planting, versus management practices in avocado production systems in the Black River basin of Antioquia - Colombia.. It was found that the productive systems of avocado, he presents high diversity of plants accompanists bringing values of Shannon of 2.26 for the mechanical managing (MM) and 2.69 for mixed managing (MMx), whereas Simpson's index, the average opposing values were 0.85 for the MM and 0.87 for the MMx. What native suggests a condition of resilience own for the productive in avocado systems of the basin.Eje A1 Sistemas de producción de base agroecológica (Trabajos científicos)Facultad de Ciencias Agrarias y Forestale

Resiliencia de la biodiversidad natural frente a las prácticas de manejo en sistemas productivos de aguacate

Las labores antrópicas sobre los sistemas productivos ocasionan deterioros ambientales y perdidas de la capacidad de los sistemas para enfrentar perturbaciones externas, pero la biodiversidad se presenta como estrategia para mitigar estos efectos y generar resistencia en pro de la eficiencia del sistema, por tanto, el objetivo de este trabajo fue evaluar la resiliencia de las biodiversidad en plantas acompañantes, frente a las prácticas de manejo en sistemas productivos de aguacate en la Cuenca del Rio Negro de Antioquia – Colombia. Se encontró que los sistemas productivos de aguacate, presenta alta diversidad de plantas acompañantes reportando valores de Shannon de 2.26 para el manejo mecánico (MM) y 2.69 para manejos mixtos (MMx), mientras que el índice de Simpson, los valores medios encontrados fueron 0.85 para las MM y 0.87 para los MMx. Lo que sugiere una condición de resiliencia natural propia para los sistemas productivos aguacateros de la cuenca.The anthropic labors on the productive systems they cause deteriorations environmental and losses of the capacity of the systems to face external disturbances, but the biodiversity appears as strategy to mitigate these effects and to generate resistance in favor of the efficiency of the system, therefore, the objective of this study was to evaluate the resilience of biodiversity in companion planting, versus management practices in avocado production systems in the Black River basin of Antioquia - Colombia.. It was found that the productive systems of avocado, he presents high diversity of plants accompanists bringing values of Shannon of 2.26 for the mechanical managing (MM) and 2.69 for mixed managing (MMx), whereas Simpson's index, the average opposing values were 0.85 for the MM and 0.87 for the MMx. What native suggests a condition of resilience own for the productive in avocado systems of the basin.Eje A1 Sistemas de producción de base agroecológica (Trabajos científicos)Facultad de Ciencias Agrarias y Forestale

Análise das infecções associadas à assistência à saúde antes e durante a pandemia de COVID-19 em um hospital colombiano

Highlights Gram-negative bacilli prevail in Healthcare-Associated Infections, revealing a microbial landscape shaped by COVID-19. Bacteremia emerges as a high-risk factor, especially impacting immunosuppressed or oncologic patients in our Colombian healthcare institution. Cephalosporin and carbapenem resistance pose a significant hurdle, emphasizing the evolving trends amidst the COVID-19 Impact on Healthcare Infections. Our study underscores the transformative impact of COVID-19 on healthcare infections, spotlighting emerging patterns and challenges in a high-complexity Colombian institution. Introduction: Healthcare-associated infections pose a significant challenge, contributing to hospital morbidity and mortality. Objective: To describe the behavior of Healthcare Associated Infections before and during the pandemic reported to a high-complexity health institution in Colombia. Material and Methods: In our retrospective observational study on Healthcare-Associated Infections (HAIs), we analyzed data from all in-patients diagnosed with HAIs between 2018 and 2020. This included clinical, demographic, microbiological, and microbial susceptibility information collected from the Committee on Nosocomial Infections' prospective database. Data from 391 isolates were obtained using Whonet software for antimicrobial resistance surveillance. Results: We found 504 cases of HAIs (2018-2020) with an overall in-hospital infection rate of 2.55/1000 patient-days. The median age for pediatric patients was 5 years, and for adults, 56 years, with 57% male. The leading admission diagnoses were oncologic disease complications (31%). Bacteremia had a 30-day mortality rate of 13%, predominantly catheter-associated (37%). Gram-negative bacilli, notably  Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa, represented 58% cases of HAI. Discussion: The critical need for specific interventions and antimicrobial management to control HAIs, especially given the challenges posed by the COVID-19 pandemic, is highlighted. Conclusions: This is the first report on HAIs incidence at a tertiary hospital in Bucaramanga, Santander (Colombia). Bacteremia was predominant; 75% of HAIs patients had comorbidities. Gram-negative bacilli prevailed; a notable rise in ICU respiratory infections occurred during the 2020 COVID-19 pandemic. Resistance to cephalosporins and carbapenems was prevalent. How to cite this article: Wintaco Luz M, Quintero-Lesmes Doris C, Vargas-Soler José A, Barrera Diego M, Palacio Laura N, Granados Ulises, Uribe Luis G “Analysis Healthcare Infections before and during of COVID-19 pandemic in a Colombian hospital”. Revista Cuidarte. 2024;15(1):e3624.  http://dx.doi.org/10.15649/cuidarte.3624Introducción: Las infecciones asociadas a la atención en salud (IAAS) representan un reto porque estas contribuyen a la morbilidad y mortalidad hospitalaria.  Objetivo: Describir el comportamiento de las IAAS antes y durante la pandemia, las cuales fueron reportadas a una institución de salud de alta complejidad en Colombia.  Materiales y métodos: En nuestro estudio observacional retrospectivo de las IAAS, analizamos los datos de todos los pacientes hospitalizados que fueron diagnosticados con una IAAS entre 2018 y 2020. Esto incluyó información clínica, demográfica, microbiológica y de susceptibilidad microbiana recabada de la base de datos prospectiva del Comité de Infecciones Nosocomiales. Los datos de 391 aislamientos se obtuvieron utilizando el programa informático Whonet para la vigilancia de la resistencia a los antimicrobianos. Resultados: Encontramos 504 casos de IAAS entre 2018 y 2020 con una tasa global de infección intrahospitalaria de 2,55/1000 pacientes al día. La mediana de edad de los pacientes pediátricos fue de 5 años y la de los adultos de 56 y el 57% de ellos eran varones. Los principales diagnósticos de ingreso fueron complicaciones oncológicas (31%). La bacteriemia tuvo una tasa de mortalidad a los 30 días del 13%, predominantemente asociada al uso de catéter (37%). Los bacilos gramnegativos, sobre todo Klebsiella pneumoniae, Escherichia coli y Pseudomonas aeruginosa, representaron el 58% de los casos de IAAS. Discusión: Se destaca la necesidad crítica de contar con intervenciones específicas y de gestión antimicrobiana para controlar las IAAS, especialmente teniendo en cuenta los retos que planteó la pandemia de Covid-19.  Conclusiones: Este es el primer informe sobre la incidencia de las IAAS en un hospital terciario de Bucaramanga, Santander (Colombia). La bacteriemia predominó y 75% de los pacientes con IAAS presentaban comorbilidades. Predominaron los bacilos gramnegativos y se produjo un notable aumento de las infecciones respiratorias en las UCI durante la pandemia Covid-19 de 2020. Fue prevalente la resistencia a las cefalosporinas y a los carbapenémicos. Como citar este artículo: Wintaco Luz M, Quintero-Lesmes Doris C, Vargas-Soler José A, Barrera Diego M, Palacio Laura N, Granados Ulises, Uribe Luis G “Analysis Healthcare Infections before and during of COVID-19 pandemic in a Colombian hospital”. Revista Cuidarte. 2024;15(1):e3624.  http://dx.doi.org/10.15649/cuidarte.3624Introdução: As infeções associadas aos cuidados de saúde representam um desafio significativo, contribuindo para a morbilidade e mortalidade hospitalar.   Objetivo: Descrever o comportamento das Infecções Relacionadas à Assistência à Saúde antes e durante a pandemia notificadas a uma instituição de saúde de alta complexidade na Colômbia. Material e Métodos: Em nosso estudo observacional retrospectivo sobre Infecções Relacionadas à Assistência à Saúde (IRAS), analisamos dados de todos os pacientes internados com diagnóstico de IRAS entre 2018 e 2020. Isso incluiu informações clínicas, demográficas, microbiológicas e de suscetibilidade microbiana coletadas do Comitê no banco de dados prospectivo de infecções hospitalares. Os dados de 391 isolados foram obtidos utilizando o software Whonet para vigilância da resistência antimicrobiana. Resultados:  Foram encontrados 504 casos de IRAS (2018-2020) com taxa global de infecção hospitalar de 2,55/1.000 pacientes-dia. A idade média para pacientes pediátricos foi de 5 anos, para adultos 56 anos, sendo 57% do sexo masculino. Os principais diagnósticos de admissão foram complicações  de doenças oncológicas (31%). A bacteremia teve uma taxa de mortalidade em 30 dias de 13%, predominantemente   associada ao cateter (37%). Bacilos Gram-negativos, notadamente Klebsiella pneumoniae, Escherichia coli e Pseudomonas aeruginosa, representaram 58% dos casos de IRAS. Discussão: É destacada a necessidade crítica de intervenções específicas e gestão antimicrobiana para controlar as IACS, especialmente tendo em conta os desafios colocados pela pandemia da COVID-19. Conclusões: Este é o primeiro relatório sobre a incidência de IRAS em um hospital terciário em Bucaramanga, Santander (Colômbia). A bacteremia foi predominante; 75% dos pacientes com IRAS apresentavam comorbidades. Prevaleceram bacilos Gram-negativos; um aumento notável nas infecções respiratórias em UTI ocorreu durante a pandemia de COVID-19 de 2020. A resistência à cefalosporina e aos carbapenêmicos foi prevalente. Como citar este artículo: Wintaco Luz M, Quintero-Lesmes Doris C, Vargas-Soler José A, Barrera Diego M, Palacio Laura N, Granados Ulises, Uribe Luis G “Analysis Healthcare Infections before and during of COVID-19 pandemic in a Colombian hospital”. Revista Cuidarte. 2024;15(1):e3624.  http://dx.doi.org/10.15649/cuidarte.362

PIXE Analysis Of Atmospheric Aerosols Related To Their Cytotoxic And Genotoxic Effects

ABSTRACT Results are given of a study regarding the relationship of composition of airborne particles in Mexico City (PM 15 , PM 10 and PM 2.5 ) with citotoxic/genotoxic effects on cell cultures. Elemental analysis of samples collected during the first half of 2002 at three sites was carried out with PIXE, together with several citotoxic/genotoxic studies (generation of •OH, cellular death, inflammatory responses, and damage to cellular DNA). Differences were found in elemental contents in the aerosols from the three sites. The results suggest that some of the latter effects are correlated to higher concentrations of certain elements in the particles

Analysis of Healthcare-associated Infections before and during the COVID-19 pandemic in a Colombian hospital

Introduction: Healthcare-associated infections pose a significant challenge, contributing to hospital morbidity and mortality. Objective: To describe the behavior of Healthcare Associated Infections before and during the pandemic reported to a high-complexity health institution in Colombia. Material and Methods: In our retrospective observational study on Healthcare-Associated Infections (HAIs), we analyzed data from all in-patients diagnosed with HAIs between 2018 and 2020. This included clinical, demographic, microbiological, and microbial susceptibility information collected from the Committee on Nosocomial Infections' prospective database. Data from 391 isolates were obtained using Whonet software for antimicrobial resistance surveillance. Results: We found 504 cases of HAIs (2018-2020) with an overall in-hospital infection rate of 2.55/1000 patient-days. The median age for pediatric patients was 5 years, and for adults, 56 years, with 57% male. The leading admission diagnoses were oncologic disease complications (31%). Bacteremia had a 30-day mortality rate of 13%, predominantly catheter-associated (37%). Gram-negative bacilli, notably Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa, represented 58% cases of HAI. Discussion: The critical need for specific interventions and antimicrobial management to control HAIs, especially given the challenges posed by the COVID-19 pandemic, is highlighted. Conclusions: This is the first report on HAIs incidence at a tertiary hospital in Bucaramanga, Santander (Colombia). Bacteremia was predominant; 75% of HAIs patients had comorbidities. Gram-negative bacilli prevailed; a notable rise in ICU respiratory infections occurred during the 2020 COVID-19 pandemic. Resistance to cephalosporins and carbapenems was prevalent

Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention

The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation. Similar dose responses were observed for cell migration, i.e. SFN at 2.5 µM increased cell migration in bladder cancer T24 cells to 128% whilst high levels inhibited cell migration. This hormetic action was also found in an angiogenesis assay where SFN at 2.5 µM promoted endothelial tube formation (118% of the control), whereas at 10-20 µM it caused significant inhibition. The precise mechanism by which SFN influences promotion of cell growth and migration is not known, but probably involves activation of autophagy since an autophagy inhibitor, 3-methyladenine, abolished the effect of SFN on cell migration. Moreover, low doses of SFN offered a protective effect against free-radical mediated cell death, an effect that was enhanced by co-treatment with selenium. These results suggest that SFN may either prevent or promote tumour cell growth depending on the dose and the nature of the target cells. In normal cells, the promotion of cell growth may be of benefit, but in transformed or cancer cells it may be an undesirable risk factor. In summary, ITCs have a biphasic effect on cell growth and migration. The benefits and risks of ITCs are not only determined by the doses, but are affected by interactions with Se and the measured endpoint