Termination of Parental Rights as a Reason of Social Orphanhood in Russia

Termination of Parental Rights as a Reason of Social Orphanhood in Russia / O. A. Volkova [et al.] // The Social Sciences. - 2016. - N11(5).-P. 6854-6857. - Refer.: p. 6857.The study presents the results of a sociological survey, conducted in 2016 in the framework of the research project “life trajectories of children and their biological parents, restored their parental rights” in Belgorod, Saratov regions and the Trans-Baikal regio

Russian Focus on The Problem of Disability

Russian Focus on The Problem of Disability / O. A. Volkova [et al.] // Research Journal of Pharmaceutical, Biological and Chemical Sciences. - 2016. - N7(6).-P. 3247-3252. - Refer.: p. 3251-3252.The article is considering the problems of marking disability in Russian society and social policy. Statistical data and the results of authors' research are presented here. The authors try to consider the social changes in the context of problems of disabled people and some aspects of social citizenship of disabled peopl

Current State of Orphanhood Issue in Russia: Regional Context

Current State of Orphanhood Issue in Russia: Regional Context / O. A. Volkova [et al.] // The Social Sciences. - 2016. - N11(5).-P. 6858-6861. - Refer.: p. 6861.The study presents the analysis of the theoretical and practical experience of Belgorod, Saratov regions and Trans-Baikal region to address the issue of child abandonment on the basis of statistical data for the 5 year period (2011 -2015). This study was prepared in the framework of the research “Life trajectories of children and their biological parents, restored their parental rights

A Contractor Based on Convex Interval Taylor

International audienceInterval Taylor has been proposed in the sixties by the interval analysis community for relaxing continuous non-convex constraint systems. However, it generally produces a non-convex relaxation of the solution set. A simple way to build a convex polyhedral relaxation is to select a corner of the studied domain/box as expansion point of the interval Taylor form, instead of the usual midpoint. The idea has been proposed by Neumaier to produce a sharp range of a single function andby Lin and Stadtherr to handle n × n (square) systems of equations. This paper presents an interval Newton-like operator, called X-Newton, that iteratively calls this interval convexification based on an endpoint interval Taylor. This general-purpose contractor uses no preconditioning and can handle any system of equality and inequality constraints. It uses Hansen's variant to compute the interval Taylor form and uses two opposite corners of the domain for every constraint. The X-Newton operator can be rapidly encoded, and produces good speedups in constrained global optimization and constraint satisfaction. First experiments compare X-Newton with affine arithmetic

EFFICACY AND TOLERABILITY OF GENERIC ZOLEDRONIC ACID 5 MG (REZOCLASTIN PS) IN THE TREATMENT OF OSTEOPOROSIS: A RETROSPECTIVE ANALYSIS OF CLINICAL EXPERIENCE WITH THE DRUG IN RUSSIA

Objectives. To analyze clinical data of the first domestic zoledronic acid generic preparation for the treatment of osteoporosis (Rezoclastin PS., 5 mg). Materials and Methods. The study included data from 123 patients (118 women and 5 men) treated with Rezoclastin PS 5 mg in medical centers of Moscow, St.-Petersburg and Krasnodar for primary (91.8%) or secondary(8.2%) osteoporosis, with mean age 27-78 years (61,4 ± 9,1 years). 56.6% of patients had severe osteoporosis with compressive deformations of vertebrae. Duration of medical therapy ranged from 6 to 24 months. Results. Study of changers in bone resorption marker CTx (n = 10) showed decline by 78% after 3 months of treatment compared to baseline (p = 0.027). BMD at the lumbar segment of the spine L 1-L 4 increased after 12 months by 3.4% (p <0.001, n = 87) and 24 months by 5.7% (p <0.05, n = 11) at the femoral neck - by 1.6% (p <0.0001, n = 64) and by 2.5% (p <0.05, n = 11), respectively, and in the total proximal femur - by 2.6% (p <0.01, n = 64) and by 3.8% (p <0.05, n = 11), respectively. The level of back pain in the study group significantly decreased at 6 months (p <0.000001), and after 18 and 24 months the pain in most patients subsided. After the first administration of the drug in 40% of patients had adverse events, mainly due to flu-like syndrome. After the second infusion at 12 months adverse reactions rate decreased to only 22.9%, after the third infusion at 24 months to 1.8 %. Conclusions. The parameters of efficacy and adverse reactions of the generic zoledronic acid as our data show is comparable to the brand version of the drug

A speckle-interferometric device for studying the cell biological activity

A modernized device intended for diagnosing the temperature-dependent activity of cells is described. The activity of cells was determined by finding the correlation coefficient of optical signals in speckle patterns recorded at different moments of time. It is shown that, as the temperature increases from 26 to 36Y°C, variations in the optical paths in cells increase from 16 to 26 nm. This is probably associated with the physiological activity of cells-trapping of large molecules or their conglomerates. In contrast to the pre- vious variant of the device design, instead of a lipid membrane, a cell monolayer was used, which was culti- vated on a plane-parallel glass plate. In order to reduce variations in the optical path lengths in a nutrient solution, a 1.7-mm-thick plane-parallel glass plate was additionally inserted into the cuvette. The modern- ization of the device also includes heating of the cuvette with hot air flows. © Pleiades Publishing, Ltd., 2012

lsmear : a variable selection strategy for interval branch and bound solvers

International audienceSmear-based variable selection strategies are well-known and commonly used bybranch-and-prune interval-based solvers. They estimate the impact of the variables on eachconstraint of the system by using the partial derivatives and the sizes of the variable domains.Then they aggregate these values, in some way, to estimate the impact of each variable onthe whole system. The variable with the greatest impact is then selected. A problem of thesestrategies is that they, generally, consider all constraints equally important. In this work, wepropose a new variable selection strategy which first weights the constraints by using theoptimal Lagrangian multipliers of a linearization of the original problem. Then, the impactof the variables is computed with a typical smear-based function but taking into accountthe weights of the constraints. The strategy isg tested on a set of well-known benchmarkinstances outperforming significantly the classical variable selection strategie