1,383 research outputs found
The impact of sea-level rise on tidal characteristics around Australia
An established tidal model, validated for present-day conditions, is used to
investigate the effect of large levels of sea-level rise (SLR) on tidal
characteristics around Australasia. SLR is implemented through a uniform
depth increase across the model domain, with a comparison between the
implementation of coastal defences or allowing low-lying land to flood. The
complex spatial response of the semi-diurnal M2 constituent does not
appear to be linear with the imposed SLR. The most predominant features of
this response are the generation of new amphidromic systems within the Gulf
of Carpentaria and large-amplitude changes in the Arafura Sea, to the north
of Australia, and within embayments along Australia's north-west coast.
Dissipation from M2 notably decreases along north-west Australia but is
enhanced around New Zealand and the island chains to the north. The diurnal
constituent, K1, is found to decrease in amplitude in the Gulf of
Carpentaria when flooding is allowed. Coastal flooding has a profound impact
on the response of tidal amplitudes to SLR by creating local regions of
increased tidal dissipation and altering the coastal topography. Our results
also highlight the necessity for regional models to use correct open boundary
conditions reflecting the global tidal changes in response to SLR.</p
Further evidence for linearly-dispersive Cooper pairs
A recent Bose-Einstein condensation (BEC) model of several cuprate
superconductors is based on bosonic Cooper pairs (CPs) moving in 3D with a
quadratic energy-momentum (dispersion) relation. The 3D BEC condensate-fraction
vs. temperature (T/Tc, where Tc is the BEC transition temperature) formula
poorly fits penetration-depth data for two cuprates in the range (1/2, 1]. We
show how these fits are dramatically improved assuming cuprates to be quasi-2D,
and how equally good fits obtain for conventional 3D and quasi-1D nanotube
superconducting data, provided the correct CP dispersion is assumed in BEC at
their assumed corresponding dimensionalities. This is offered as additional
concrete empirical evidence for linearly-dispersive pairs in another recent BEC
scenario of superconductors within which a BCS condensate turns out to be a
very special case.Comment: 9 pages, 1 figur
Prophylactic balloon angioplasty fails to prolong the patency of expanded polytetrafluoroethylene arteriovenous grafts: Results of a prospective randomized study
AbstractPurpose: Maintenance of hemodialysis access grafts represents an enormous social and clinical problem. Current grafts and graft salvage techniques are inadequate. Consequently, there has been increasing interest in the use of minimally invasive catheter techniques to prophylactically treat stenoses in functioning arteriovenous grafts. Prophylactic balloon angioplasty has been widely suggested as prolonging assisted primary patency. We have performed a prospective randomized trial to compare patients who underwent percutaneous transluminal angioplasty (PTA) for graft stenoses >50% with a control group that received no intervention. Our hypothesis was that to be efficacious a minimal benefit of 20% prolongation in patency would be necessary.Methods: Color flow duplex scanning was used to detect >50% stenoses in functioning expanded polytetrafluoroethylene grafts. Patients were then subjected to confirmatory angiographic evaluation. Those who had angiographic stenoses >50% were randomized to balloon angioplasty or observation. Patients were followed-up with duplex scanning every 2 months. Statistical analysis was performed using the Kaplan-Meier technique. Although demographically the patient groups were well matched, there were more prior interventions and concurrent central stenoses in the treatment group. Outcomes were graft thrombosis, graft dysfunction that precluded dialysis, and six or more PTA procedures within 18 months.Results: In the treatment and observation groups, the 6-month patency rates were 69% ± 7% and 70% ± 7%, respectively. The 12-month patency rates for the treatment and observation groups were 51% ± 6% and 47% ± 4%, respectively. There was no significant difference between these two groups ( p = 0.97), with an 80% confidence limit for detection of a difference greater than 20%.Conclusions: This study demonstrates that a generic approach of PTA to treat all polytetrafluoroethylene grafts with stenoses >50% does not prolong patency and cannot be supported
Foregrounds for observations of the cosmological 21 cm line: II. Westerbork observations of the fields around 3C196 and the North Celestial Pole
In the coming years a new insight into galaxy formation and the thermal
history of the Universe is expected to come from the detection of the highly
redshifted cosmological 21 cm line. The cosmological 21 cm line signal is
buried under Galactic and extragalactic foregrounds which are likely to be a
few orders of magnitude brighter. Strategies and techniques for effective
subtraction of these foreground sources require a detailed knowledge of their
structure in both intensity and polarization on the relevant angular scales of
1-30 arcmin. We present results from observations conducted with the Westerbork
telescope in the 140-160 MHz range with 2 arcmin resolution in two fields
located at intermediate Galactic latitude, centred around the bright quasar
3C196 and the North Celestial Pole. They were observed with the purpose of
characterizing the foreground properties in sky areas where actual observations
of the cosmological 21 cm line could be carried out. The polarization data were
analysed through the rotation measure synthesis technique. We have computed
total intensity and polarization angular power spectra. Total intensity maps
were carefully calibrated, reaching a high dynamic range, 150000:1 in the case
of the 3C196 field. [abridged]Comment: 20 pages, 22 figures, accepted for publication in A&A. A version with
full resolution figures is available at
http://www.astro.rug.nl/~bernardi/NCP_3C196/bernardi.pd
Development and mapping of SNP assays in allotetraploid cotton
A narrow germplasm base and a complex allotetraploid genome have made the discovery of single nucleotide polymorphism (SNP) markers difficult in cotton (Gossypiumhirsutum). To generate sequence for SNP discovery, we conducted a genome reduction experiment (EcoRI, BafI double digest, followed by adapter ligation, biotin–streptavidin purification, and agarose gel separation) on two accessions of G. hirsutum and two accessions of G. barbadense. From the genome reduction experiment, a total of 2.04 million genomic sequence reads were assembled into contigs with an N50 of 508 bp and analyzed for SNPs. A previously generated assembly of expressed sequence tags (ESTs) provided an additional source for SNP discovery. Using highly conservative parameters (minimum coverage of 8× at each SNP and 20% minor allele frequency), a total of 11,834 and 1,679 non-genic SNPs were identified between accessions of G. hirsutum and G. barbadense in genome reduction assemblies, respectively. An additional 4,327 genic SNPs were also identified between accessions of G. hirsutum in the EST assembly. KBioscience KASPar assays were designed for a portion of the intra-specific G. hirsutum SNPs. From 704 non-genic and 348 genic markers developed, a total of 367 (267 non-genic, 100 genic) mapped in a segregating F2 population (Acala Maxxa × TX2094) using the Fluidigm EP1 system. A G. hirsutum genetic linkage map of 1,688 cM was constructed based entirely on these new SNP markers. Of the genic-based SNPs, we were able to identify within which genome (‘A’ or ‘D’) each SNP resided using diploid species sequence data. Genetic maps generated by these newly identified markers are being used to locate quantitative, economically important regions within the cotton genome
Beta-delayed-neutron studies of Sb and I performed with trapped ions
Beta-delayed-neutron (n) spectroscopy was performed using the
Beta-decay Paul Trap and an array of radiation detectors. The n
branching ratios and energy spectra for Sb and I were
obtained by measuring the time of flight of recoil ions emerging from the
trapped ion cloud. These nuclei are located at the edge of an isotopic region
identified as having n branching ratios that impact the r-process
abundance pattern around the A~130 peak. For Sb and I,
n branching ratios of 14.6(11)%, 17.6(28)%, and 7.6(28)% were
determined, respectively. The n energy spectra obtained for Sb
and I are compared with results from direct neutron measurements, and
the n energy spectrum for Sb has been measured for the first
time
In Defense of the Epistemic Imperative
Sample (2015) argues that scientists ought not to believe that their theories are true because they cannot fulfill the epistemic obligation to take the diachronic perspective on their theories. I reply that Sample’s argument imposes an inordinately heavy epistemic obligation on scientists, and that it spells doom not only for scientific theories but also for observational beliefs and philosophical ideas that Samples endorses. I also delineate what I take to be a reasonable epistemic obligation for scientists. In sum, philosophers ought to impose on scientists only an epistemic standard that they are willing to impose on themselves
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