Influence of combined methods of rehabilitation on the level of biochemical markers of overtraining in combat sports athlete

Objective: to investigate markers of anaerobic energy supply in overworked athletes after the combination rehabilitation. Materials and methods: all athletes were divided into two subgroups: 2nd A-subgroup (23 persons) - overworked athletes with combined rehabilitation and 2nd B-subgroup (24th) - athletes with traditional rehabilitation. Results: concentration of lactic acid in the blood of athletes of the 2nd A subgroup at rest is minimal in comparison with the 2nd B subgroup and 1-group athletes, P < 0,05-0,01. After the stress test there is an increase in the concentration of lactic acid in the 2nd A subgroup, P < 0.01. After the stress test athletes 2nd A subgroups, the level of lactate dehydrogenase is higher than that of athletes 2nd B subgroups. Conclusions: low concentration of lactic acid at rest in athletes of the 2nd A subgroup indicates the adaptation and energy saving of these young men, which is due to the prevalence of aerobic mechanisms in energy supply

EpiCompare: R package for the comparison and quality control of epigenomic peak files

Summary EpiCompare combines a variety of downstream analysis tools to compare, quality control and benchmark different epigenomic datasets. The package requires minimal input from users, can be run with just one line of code and provides all results of the analysis in a single interactive HTML report. EpiCompare thus enables downstream analysis of multiple epigenomic datasets in a simple, effective and user-friendly manner. Availability and Implementation EpiCompare is available on Bioconductor (≥ v3.15): https://bioconductor.org/packages/release/bioc/html/EpiCompare.html All source code is publically available via GitHub: https://github.com/neurogenomics/EpiCompare Documentation website https://neurogenomics.github.io/EpiCompare EpiCompare DockerHub repository: https://hub.docker.com/repository/docker/neurogenomicslab/epicompare Competing Interest Statement The authors have declared no competing interest

Clinical and epidemiological characteristics of Yersinia infection in the north of the Volga-Vyatka region

The objective: to describe clinical and epidemiological picture of Yersinia infection in the Kirov region.Materials and methods: the study included 40 patients, ranging in age from 17 to 69 years: 36 patients with a diagnosis of yersiniosis, 4 – pseudotuberculosis. The diagnosis was confirmed by the method of indirect hemagglutination Yersinia and pseudotuberculosis diagnosis.Results of research: Yersinia infection in the Kirov region in all cases was accompanied by intoxication. Catarrhal syndrome and rash was detected in 2/3 of patients. Generalized form of the disease was characterized by liver disease in most patients. Almost half of the patients had lesions of the musculoskeletal system and the effects of gastroenteritis were recorded in 35% of cases. Factor for the development of chronic Yersinia infection is burdened premorbid background.Conclusion: For the prevention of adverse outcomes Yersinia infection requires a comprehensive approach to the treatment of patients with severe premorbid background. Such patients should be allocated to risk group. Subsequent clinical supervision must be exercised within a period of 1 year with doctors of other specialties

APPROACHES TO THE FUTURE ENGINEERS FOREIGN COMMUNICATIVE CULTURE FORMATION

Purpose: The main aim of the article is to define the approaches to the formation of future engineers’ communicative culture. The main research method used while working on the article is analysis of the domestic and foreign publication space for critical consideration of different ideas on the pedagogical problem of the future engineers’ foreign language communicative culture formation process. Methodology: In this study Content abstraction, generalization and the comparative method was applied. Result: The approaches (cultural, connectivism, technological, axiological, communicative, environmental approach) will help to the formation of the communicative culture of future engineers in the process of foreign language training. Applications: This research can be used for engineers and companies. Novelty/Originality: In this research, the model of approaches to future engineers' foreign communicative culture formation is presented in a comprehensive and complete manner

Preparation, Surface active properties, and Anticorrosion Application of some novel surfactants based on cottonseed oil and diethanolamine on carbon steel in CO2 environments

Novel surfactants were synthesized based on cottonseed oil and diethanolamine and the structures of these compounds were confirmed by FTIR spectroscopy. The surface and thermodynamic properties of these compounds have been investigated. The corrosion behavior of the synthesized surfactant corrosion inhibitors was evaluated by using potentiodynamic (Tafel) polarization curves, linear polarization resistance corrosion rate techniques. The experimental results showed that these inhibitors revealed a very good corrosion inhibition even at low concentrations. The protection efficiency increased with increasing inhibitor concentration, getting maximum values ranged between 87.37 and 97.91 % at 100 ppm after 20 hour of exposure. The adsorption process was found to obey the Langmuir adsorption isotherm

Клинико-эпидемиологическая характеристика иерсиниозной инфекции на севере Волго-Вятского региона

The objective: to describe clinical and epidemiological picture of Yersinia infection in the Kirov region.Materials and methods: the study included 40 patients, ranging in age from 17 to 69 years: 36 patients with a diagnosis of yersiniosis, 4 – pseudotuberculosis. The diagnosis was confirmed by the method of indirect hemagglutination Yersinia and pseudotuberculosis diagnosis.Results of research: Yersinia infection in the Kirov region in all cases was accompanied by intoxication. Catarrhal syndrome and rash was detected in 2/3 of patients. Generalized form of the disease was characterized by liver disease in most patients. Almost half of the patients had lesions of the musculoskeletal system and the effects of gastroenteritis were recorded in 35% of cases. Factor for the development of chronic Yersinia infection is burdened premorbid background.Conclusion: For the prevention of adverse outcomes Yersinia infection requires a comprehensive approach to the treatment of patients with severe premorbid background. Such patients should be allocated to risk group. Subsequent clinical supervision must be exercised within a period of 1 year with doctors of other specialties.Цель: характеристика клинико-эпидемиологической картины иерсиниозной инфекции в Кировской области.Материалы и методы: обследовано 40 человек в возрасте от 17 до 69 лет, из них 36 пациентов с диагнозом иерсиниоз, 4 – псевдотуберкулез. Диагноз подтвержден методом РНГА с кишечноиерсиниозным и псевдотуберкулезными диагностикумами.Результаты: иерсиниозная инфекция в Кировской области во всех случаях сопровождалась интоксикацией. Катаральный синдром и экзантема выявлены у 2/3 обследованных. Генерализованная форма заболевания протекала с поражением печени у большинства больных. Почти половина пациентов страдала поражением опорно-двигательного аппарата, явления гастроэнтерита регистрировались в 35% случаях. Предраспологающим фактором для развития хронического течения иерсиниозной инфекции является отягощенный преморбидный фон.Заключение: для предупреждения неблагоприятных исходов иерсиниозной инфекции необходим комплексный подход к лечению больных с отягощенным преморбидным фоном. Таких пациентов следует выделять в группу риска. Последующее диспансерное наблюдение должно осуществляться в течение 1 года с привлечением врачей других специальностей

The lithological-petrography characteristics of chalk, paleogen-miocene deposits of Yalama-Khudat areas and Siyazan monocline anticline in connection with their oil and gas content (south-east immersions of megaanticlinoric of Greater Caucasus)

In recent years, geological prospecting and geophysical works in Azerbaijan were carried out in considerable volume in order to study an oil and gas potential of Meso-Cenozoic deposits. Based on the results of these studies the criteria were developed as the basis for further research. It is known that the sedimentation basin mainly dipped in the Meso-Cenozoic time. As a result, the researchers have no doubt about the potential of these deposits in the central part of the studied area and at greater depths, but there have been no precise calculations yet. In order to solve this problem, we have studied the reservoir rocks properties of considered ages of Khudat, Yalama oil and gas bearing structures and Siyazan monocline formed in Gusar-Davachi superimposed mulde in various geological conditions and at different depths. For an easier analysis, all the actual data are given in tables showing the physical parameters of the different rock types, involved in geological structure of oil and gas bearing areas. In order to clarify the obtained results and the changes nature study of the considered physical properties the various petrophysical methods were applied. As a result the regularity in changing of rocks density, carbonate contents, porosity, permeability and the propagation velocity of ultrasonic waves in them were established. However, in tectonically complex structures of the Siyazan monocline the applied methods have not given expected results of studies because of their severe dislocation and outlet to the surface. Taking this into account the reservoir characteristics studies of rock samples of considered ages from fields being developed in the north-eastern slope of the south-east Greater Caucasus dipping were conducted. The main objective is to study the petrophysical parameters and reservoir rocks properties of the Cretaceous, Paleogene-Miocene age in tectonically complex uplifts of Yalama, Khudat and Siyazan monocline placed at southeast Greater Caucasus dipping due to its petroleum potential

Performance of a plastic scintillator developed using styrene monomer polymerization

This paper presents a newly developed plastic scintillator produced in collaboration with Turkiye Energy, Nuclear and Mineral Research Agency (TENMAK). The scintillator is manufactured using thermal polymerization of commercially available styrene monomer. The absorption spectrum of the scintillator exhibited two absorption bands at 225 nm and 340 nm, with an absorption edge observed at 410 nm. The wavelength of the emitted light was measured in the range of 400-800 nm, with a maximum intensity at 427 nm. Monoenergetic electrons from the 137Cs source were used to evaluate the characteristics of the new scintillator, particularly its light yield. As the light readout the MAPD-3NM type silicon photomultiplier array (4 x 4) with an active area of 15 x 15 mm2, assembled using single MAPDs with an active area of 3.7 x 3.7 mm2, was used. The light yield of the scintillator was determined to be 6134 photons/MeV. In addition, the efficiency of the scintillator for gamma rays with an energy of 662 keV was found to be approximately 1.8 %. A CmBe neutron source was employed to evaluate its fast neutron detection performance. However, neutron/gamma discrimination using pulse shape discrimination (charge integration) method was not observed. The results demonstrate the potential of a newly produced plastic scintillator for various applications, particularly in radiation monitoring and detection systems.Comment: 7 pages, 7 figure

Manifestation of type 2 diabetes mellitus in the background of COVID-19: review and clinical case

The article presents a literature review of clinical data on the manifestation of type 2 diabetes mellitus against the background of coronavirus infection COVID-19, COVID-19 is considered as a possible cause of type 2 diabetes. A clinical case of a patient with coronavirus infection and newly diagnosed type 2 diabetes mellitus was presentedВ статье приведен литературный обзор клинических данных о манифестации сахарного диабета 2 типа на фоне коронавирусной инфекции COVID-19, COVID-19 рассмотрен как возможная причина возникновения сахарного диабета 2 типа. Приведен клинический случай пациентки с коронавирусной инфекцией и впервые диагностированным сахарным диабетом 2 типа

Нейроэндокринные опухоли мочевыделительной системы: обзор литературы

Most often, neuroendocrine carcinoma (NEC) is found in the gastrointestinal tract, broncho-pulmonary system, but they can also occur in other organs, such as the kidney, bladder, which is of most interest because of the rarity of this pathology. Until recently, there was not even a proper morphological classification for kidney NEC, and among some histological types, such as large cell neuroendocrine carcinoma of the kidney, only about 7 cases were recorded, and independent bladder carcinoids, about 15 cases. Currently, there are no clinical and morphological features of the NEC of the kidney and bladder, fundamentally distinguishing them from other neuroendocrine tumors and “classic” cancer of the same localization. This article also provides the data of the N.N. Blokhin National Medical Research Centre of Oncology on the incidence of all malignant neoplasms of the urinary system.Наиболее часто нейроэндокринные неоплазии (neuroendocrine carcinoma, NEC) встречаются в желудочно-кишечном тракте и бронхолегочной системе, однако могут возникать и в других органах, таких как почки, мочевой пузырь, что представляет большой интерес ввиду редкости этих новообразований. До недавнего времени отсутствовала морфологическая классификация NEC почки. Среди некоторых гистологических типов, например таких как крупноклеточная нейроэндокринная карцинома почки, зафиксировано всего 7 случаев, а самостоятельных высокодифференцированных нейроэндокринных карцином мочевого пузыря – 15. В настоящее время не существует клинических и морфологических особенностей NEC почки и мочевого пузыря, принципиально отличающих их от других нейроэндокринных опухолей и «классического» рака той же локализации. В настоящей статье представлены сравнительные данные НМИЦ онкологии им Н. Н. Блохина по заболеваемости NEC и другими злокачественными новообразованиями мочевыделительной системы