44 research outputs found
A Survey of Bayesian Statistical Approaches for Big Data
The modern era is characterised as an era of information or Big Data. This
has motivated a huge literature on new methods for extracting information and
insights from these data. A natural question is how these approaches differ
from those that were available prior to the advent of Big Data. We present a
review of published studies that present Bayesian statistical approaches
specifically for Big Data and discuss the reported and perceived benefits of
these approaches. We conclude by addressing the question of whether focusing
only on improving computational algorithms and infrastructure will be enough to
face the challenges of Big Data
Progressive hemorrhage and myotoxicity induced by echis carinatus venom in murine model: neutralization by inhibitor cocktail of n,n,n `,n `-tetrakis (2-pyridylmethyl) ethane-1,2-diamine and silymarin
Viperbite is often associated with severe local toxicity, including progressive hemorrhage and myotoxicity, persistent even after the administration of anti-snake venom (ASV). In the recent past, investigations have revealed the orchestrated actions of Zn2+ metalloproteases (Zn(2+)MPs), phospholipase A(2)s (PLA(2)s) and hyaluronidases (HYs) in the onset and progression of local toxicity from the bitten site. As a consequence, venom researchers and medical practitioners are in deliberate quest of potent molecules alongside ASV to tackle the brutal local manifestations induced by aforesaid venom toxins. Based on these facts, we have demonstrated the protective efficacy of inhibitor cocktail containing equal ratios of N,N,N', N'-tetrakis (2-pyridylmethyl) ethane-1,2-diamine (TPEN) and silymarin (SLN) against progressive local toxicity induced by Echis carinatus venom (ECV). In our previous study we have shown the inhibitory potentials of TPEN towards Zn(2+)MPs of ECV (IC50: 6.7 mu M). In this study we have evaluated in vitro inhibitory potentials of SLN towards PLA(2)s (IC50: 12.5 mu M) and HYs (IC50: 8 mu M) of ECV in addition to docking studies. Further, we have demonstrated the protection of ECV induced local toxicity with 10 mM inhibitor cocktail following 15, 30 min (for hemorrhage and myotoxicity); 60 min (for hemorrhage alone) of ECV injection in murine model. The histological examination of skin and thigh muscle sections taken out from the site of ECV injection substantiated the overall protection offered by inhibitor cocktail. In conclusion, the protective efficacy of inhibitor cocktail is of high interest and can be administered locally alongside ASV to treat severe local toxicity
Long term effect of nutrient management on soil quality and sustainable productivity under sorghum-wheat crop sequence in Vertisol of Akola, Maharashtra
Supervisory Predictive Control Of Standalone Wind/solar Energy Generation Systems
This paper presents a supervisory model predictive control method for the optimalmanagementand operation of hybrid standalone wind-solar energy generation. Thiswork present supervisorycontrol system through modelpredictive control which calculates thepower references for the wind and solar subsystems at each sampling time while minimizing asuitable cost function. Inthis paper wediscuss how toextend the life time of the equipment by reducing the peak values of inrush or surge currents, into the formulation of the model predictive control optimization problem. Wepresentseveral simulation of this system
A Review Paper on Planning of Solid Waste Management Plant – a Case Study for Indapur City
This paper gives the review about the existing solid waste management practices and present scenario of solid waste practices in Indapur city .The unplanned growth of the city has created the problem of waste generation . The per capita waste rate in India has increased from 0.53 kg per day in 2001 to 0.68 kg per day in 2013; this increased solid waste made a huge impact on environment as well as human life. So, there is requirement of proper solid waste management to reduce the effect on of environment and human life
A Review Paper on Planning of Solid Waste Management Plant – a Case Study for Indapur City
This paper state that existing solid waste management practices in Indapur municipal area of Pune district of Maharashtra state, India. Solid waste management is among the basic essential services provided by municipal authorities in the country to keep cities clean. Due to industrialization, rural to urban migration and high growth rate of population have induced rapid urbanisation in developing countries and obviously in India also. The haphazard urbanisation created acute problem of solid waste management. The per capita waste generation rate in India has increased from 0.44 kg per day in 2001 to 0.5 kg per day in 2011; such a steep increase in waste generation within a decade has severed the stress on all infrastructural, natural and budgetary resources. Pune is one of the developing city, it generates total quantity of waste is about 7 tons per day. So, there is need of the proper waste collection, transportation route for prevention of environment form the hazardous waste disposal. It may help in sustainable urban environment of Indapur city. For effective management, the municipal corporation of Indapur has divided the entire region into seventeen wards which are further divided into six health units to collect the solid waste. Two alternate disposal systems are considered. In first case the entire solid waste of the city of Indapur is dumped at one dumping site. In next case there are three sites proposed at different locations in the city Indapur cit