An Analysis of English-language YouTube Videos Related to Minamata Disease: Prior to the Release of the Hollywood Film “Minamata”

application/pdfThis study investigates the state of online English-language video content related to Minamata Disease available prior to the 2020 release of the Hollywood film “Minamata” starring popular actor Johnny Depp (in the role of photojournalist W. Eugene Smith). It is intended to serve as a case study of depictions of historic environmental incidents and as a baseline for future comparative research. Utilizing a mixed quantitative and qualitative approach, the study inventoried relevant uploads to YouTube, analyzing in detail the 27 most-viewed videos. Findings include that uploads encompass a wide range of durations, viewcounts, and approaches chosen for portraying the topic. Most had evidently been uploaded by non-specialists (notably as the sole channel upload in 7 cases). Many were produced through excerpting previously existing source materials – mainly a small number of historic documentary films (most notably a 1971 film by Tsuchimoto Noriaki). Uploads often present low-resolution, deteriorated source content, with varying degrees of alterations and additions having been made, and generally lack explanations of the context or the significance of visual material presented. The most-viewed item was a 2017 upload by popular YouTube channel SciShow, which was highly unusual in that it focused on biochemistry and included no depictions of symptoms in diseased humans or cats. Additional findings and observations are presented, and relevant implications are discussed; future research directions are also identified.departmental bulletin pape

Functional role of Transforming growth factor beta during enamel formation

研究成果の概要（和文）：エナメル質形成過程に認められるトランスフォーミング成長因子ベータ(TGF-β)に注目し、その役割と機能解明を目指し、主にTGF-β１のタンパク質動態について調べた。これまでに、エナメル芽細胞によるTGF-β１のオートクリン機構と、エナメルマトリックス内でTGF-β１がアメロゲニン断片（Amel）と複合体を形成することを解明した。またTGF-βの役割についてエナメル芽細胞のアポトーシス誘導、アメロゲニンのエンドサイトーシス、および上皮間葉転換誘導の可能性を見出している。さらにこれらの働きに及ぼす影響はTGF-βアイソフォーム間（β1、β2、β3）で違いを示すことが分かった。研究成果の概要（英文）：We focused on transforming growth factor beta (TGF-β), which is found in the process of enamel formation, to elucidate its role and function, and mainly investigated the protein dynamics of TGF-β1. We have elucidated the autocrine mechanism of TGF-β1 by ameloblasts and the complex formation of TGF-β1 with amelogenin fragments in the enamel matrix. We have also identified possible roles for TGF-β in the induction of apoptosis in ameloblasts, endocytosis of amelogenin, and induction of epithelial-mesenchymal transition. Furthermore, we found that the effects on these functions differ among TGF-β isoforms (β1, β2, and β3).・2021(令和3)年度 科学研究費補助金 基盤研究(C) 研究成果報告書・研究期間 (年度)：2017-04-01 – 2022-03-31・研究分野：歯学・矯正・小児系歯学・研究成果の学術的意義や社会的意義 : 本研究により、正常なエナメル質形成のメカニズム解明に迫ることのみならず、Amel-TGF-β複合体を応用した新たな歯科再生医療技術の構築が十分に考えられ、学術的および社会的意義は高い。またTGF-βアイソフォーム間による影響を検証することで、形成不全や腫瘍化に至る異常なシグナルについて知る可能性を示唆する。研究課題/領域番号 : 17K11975research repor

検察官の求刑と量刑手続の構造

3Pdepartmental bulletin pape

THE IDEAL NOTION AND ITS EMBODIMENT : THE COURTYARD HOUSE OF THE ARAB-ISLAMIC WORLD

departmental bulletin pape

自他動詞の獲得 : コーパス分析による一考察

departmental bulletin pape

Subaru Imaging of Asymmetric Features in a Transitional Disk in Upper Scorpius

We report high-resolution (0.07 arcsec) near-infrared polarized intensity images of the circumstellar disk around the star 2MASS J16042165-2130284 obtained with HiCIAO mounted on the Subaru 8.2 m telescope. We present our $H$-band data, which clearly exhibits a resolved, face-on disk with a large inner hole for the first time at infrared wavelengths. We detect the centrosymmetric polarization pattern in the circumstellar material as has been observed in other disks. Elliptical fitting gives the semimajor axis, semiminor axis, and position angle (P.A.) of the disk as 63 AU, 62 AU, and -14 $^{\circ}$, respectively. The disk is asymmetric, with one dip located at P.A.s of $\sim85^{\circ}$. Our observed disk size agrees well with a previous study of dust and CO emission at submillimeter wavelength with Submillimeter Array. Hence, the near-infrared light is interpreted as scattered light reflected from the inner edge of the disk. Our observations also detect an elongated arc (50 AU) extending over the disk inner hole. It emanates at the inner edge of the western side of the disk, extending inward first, then curving to the northeast. We discuss the possibility that the inner hole, the dip, and the arc that we have observed may be related to the existence of unseen bodies within the disk.Comment: 21 pages, 3 figures, published 2012 November 7 by ApJL, typo correcte

アジア主義と亜洲和親会をめぐって

textapplication/pdfdepartmental bulletin pape