125 research outputs found
Henry Bush
26-1Revolutionary PensionsReport : Memorial of H. Bush. [370] Indian hostilities in 1778.1840-5
Ogden Land Company.
54-2Memorial of the Seneca Nation. [3471] Protesting the proposed purchase by the U.S. of title to lands within the Allegany and Cattaraugus reservations, New York; this title is in the hands of the Ogden Land Co.1897-9
James Hall -- Legal representatives of
34-3Private Land ClaimsReport : Memorial of J. Hall. [912] Cession of land in Arkansas to the Cherokees.1857-2
Military posts on the road from Missouri to New Mexico.
35-2Military AffairsReport on Military Posts. [1018] From Missouri to New Mexico; Kiowa and Comanche country.1859-3
Pawnee Indians. Message from the President of the United States, transmitting a communication from the Secretary of the Interior in reference to the necessities of the Pawnee Indians.
44-1Indian AffairsMessage on the Pawnees. [1689] Recently removed to Indian Territory, and in need of supplies.1876-8
Turtle Mountain Band of Pembina Chippewa Indians
55-2Indian AffairsPetition and Memorial of the Turtle Mountain Band of Chippewas. [3600] Concerns claims and disputes over certain lands in North Dakota; issues surrounding cession, or relinquishment of said lands.1898-7
George M. Bedinger
27-2Revolutionary PensionsReport : Petition pf G. Bedinger. [407] Indian spy in 1779.1842-1
Hostilities with Creek Indians. Message from the President of the United States, transmitting the information required by a resolution of the House of Representatives, of the 1st of July last, in relation to the hostilities then existing with the Creek Indians, &c. &c
24-2Message on Indian Hostilities. [304] Report of the Com'rs appointed to investigate the causes of the late hostilities of the Creek Indians.1837-3
Radionuclide therapy using I-131-labeled anti-epidermal growth factor receptor-targeted nanoparticles suppresses cancer cell growth caused by EGFR overexpression
Introduction Anti-epidermal growth factor receptor (EGFR)-targeted nanoparticles can be used to deliver a therapeutic and imaging agent to EGFR-overexpressing tumor cells. I-131-labeled anti-EGFR nanoparticles derived from cetuximab were used as a tumor-targeting vehicle in radionuclide therapy
Controversy and consensus on the management of elevated sperm DNA fragmentation in male infertility: A global survey, current guidelines, and expert recommendations
Purpose
Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition.
Materials and Methods
An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method.
Results
A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4–6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated.
Conclusions
This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians
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