11 research outputs found

    (A) study on the osteoporosis risk factors of the climacteric women

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    ์ง€์—ญ์‚ฌํšŒ ๊ฐ„ํ˜ธํ•™๊ณผ/์„์‚ฌ[ํ•œ๊ธ€] ๋ณธ ์—ฐ๊ตฌ๋Š” ๊ฐฑ๋…„๊ธฐ ์—ฌ์„ฑ์—๊ฒŒ ๋ฐœ์ƒ๋˜๋Š” ๊ณจ๋‹ค๊ณต์ฆ๊ณผ ๊ด€๋ จ๋œ ์œ„ํ—˜์š”์ธ์„ ๊ทœ๋ช…ํ•˜๊ธฐ ์œ„ํ•˜์—ฌ ์‹œ๋„๋˜์—ˆ๋‹ค. 1997๋…„ 10์›” 1์ผ ๋ถ€ํ„ฐ 10์›” 31์ผ ๊นŒ์ง€ 30์ผ๊ฐ„ ์„œ์šธ์— ์œ„์น˜ํ•œ ์ข…ํ•ฉ๋ณ‘์›์ค‘ A๋ณ‘์›๊ณผ B๋ณ‘์› ๊ทธ๋ฆฌ๊ณ  C๋ณ‘์›์—์„œ ๊ณจ๋‹ค๊ณต์ฆ ์œ ๋ฌด๋ฅผ ์ง„๋‹จ ๋ฐ›๊ธฐ ์œ„ํ•ด ๋‚ด์›ํ•œ ์—ฌ์„ฑ 425๋ช…์— ๋Œ€ํ•œ ์„ค๋ฌธ์กฐ์‚ฌ๋ฅผ ์‹ค์‹œํ•˜์˜€๋‹ค. 425๋ช…์˜ ์—ฌ์„ฑ์ค‘ ์—ฐ๊ตฌ๋Œ€์ƒ์ž๋Š” 40์„ธ์—์„œ 60์„ธ ์—ฌ์„ฑ์ด๊ณ , LUNAR ์ด์ค‘ ์—๋„ˆ์ง€ ๋ฐฉ์‚ฌ์„  ํก์ˆ˜๊ณ„์ธก๊ธฐ์— ์˜ํ•ด ์ธก์ •๋œ ์ฒ™์ถ”๊ณจ(L2-L4)์˜ ๊ณจ๋ฐ€๋„๊ฐ€ ํŒ์ •๊ธฐ์ค€์ธ ํ‘œ์ค€ํŽธ์ฐจ๊ฐ’(T Score) T Score -1.0 ์ด์ƒ 109๋ช…์„ ๋Œ€์กฐ๊ตฐ์œผ๋กœ, T Score -2.4 ์ดํ•˜ 142๋ช…์„ ํ™˜์ž๊ตฐ์œผ๋กœ ํ•˜์—ฌ ์ตœ์ข… 251๋ช…์˜ ์ž๋ฃŒ๊ฐ€ ๋ถ„์„์— ์‚ฌ์šฉ๋˜์—ˆ๋‹ค. ์ž๋ฃŒ๋ถ„์„์— ์‚ฌ์šฉ๋œ ๋ณ€์ˆ˜๋Š” ๊ณจ๋‹ค๊ณต์ฆ ์œ ๋ฌด๋ฅผ ์ข…์†๋ณ€์ˆ˜๋กœ ํ•˜๊ณ  ๋…๋ฆฝ๋ณ€์ˆ˜๋กœ๋Š” ๋Œ€์ƒ์ž์˜ ์ธ๊ตฌ์‚ฌํšŒํ•™์  ์š”์ธ์œผ๋กœ ์—ฐ๋ น, ์ฒด์ค‘, ์‹ ์žฅ, ํ•™๋ ฅ, ๊ฒฝ์ œ์ •๋„์ด๊ณ , ์—ฌ์„ฑ์˜ ์ƒ์‹๊ด€๋ จ ์š”์ธ์€ ์ดˆ๊ฒฝ์—ฐ๋ น, ํ๊ฒฝ์—ฐ๋ น, ํ๊ฒฝํ˜•ํƒœ, ํ๊ฒฝ๋…„์ˆ˜, ์ž๋…€์ˆ˜, ์ž„์‹ ํšŸ์ˆ˜, ์ˆ˜์œ ๋ฐฉ๋ฒ•, ํ”ผ์ž„์•ฝ๋ณต์šฉ์ด๋‹ค. ๊ทธ๋ฆฌ๊ณ  ์œ ์ „์  ์š”์ธ์€ ๋ชจ๊ณ„์˜ ๋“ฑ ๊ตฝ์Œ๊ณผ ๊ณจ์ ˆ๋ ฅ ๊ทธ๋ฆฌ๊ณ  ๋ณธ์ธ์˜ ๊ณจ์ ˆ๋ ฅ์ด ์žˆ๊ณ , ์ƒํ™œ์–‘์‹ ์š”์ธ์œผ๋กœ๋Š” ์Œ์ฃผ, ํก์—ฐ, ์ปคํ”ผ์„ญ์ทจ, ์นผ์Š˜์„ญ์ทจ, ์šด๋™ ๊ทธ๋ฆฌ๊ณ  ๊ฐ€์‚ฌํ™œ๋™์ด ํฌํ•จ๋œ๋‹ค. ์ž๋ฃŒ๋ถ„์„ ๋ฐฉ๋ฒ•์€ ์ข…์†๋ณ€์ˆ˜์™€ ๋…๋ฆฝ๋ณ€์ˆ˜๋“ค๊ณผ์˜ ๊ด€๊ณ„ ๋ถ„์„์€ ฯ‡2-test์™€ t-test๋ฅผ ์‹ค์‹œํ•˜์˜€๊ณ , ๊ณจ๋‹ค๊ณต์ฆ์˜ ์œ„ํ—˜์š”์ธ๋“ค๊ฐ„์˜ ์ƒ๋Œ€์œ„ํ—˜๋„๋Š” ๊ต์ฐจ๋น„(Odds Ratio)๋กœ ์‚ฐ์ถœํ•˜์˜€๋‹ค. ์—ฌ๋Ÿฌ๋ณ€์ˆ˜๋“ค์ค‘ ๊ณจ๋‹ค๊ณต์ฆ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ์š”์ธ์˜ ํ™•์ธ์„ ์œ„ํ•˜์—ฌ ๋กœ์ง€์Šคํ‹ฑ ํšŒ๊ท€๋ถ„์„(logistic regression analysis)์ค‘ ๋‹จ๊ณ„์  ๋ฐฉ๋ฒ•(stepwise procedure)์ด ์‹ค์‹œ ๋˜์—ˆ๋‹ค. ๋ณธ ์—ฐ๊ตฌ์˜ ์ฃผ์š” ๊ฒฐ๊ณผ๋Š” ๋‹ค์Œ๊ณผ ๊ฐ™๋‹ค ๊ณจ๋‹ค๊ณต์ฆ ์œ„ํ—˜์š”์ธ๋“ค์„ ํ™˜์ž๊ตฐ๊ณผ ๋Œ€์กฐ๊ตฐ์œผ๋กœ ๋น„๊ต ํ•˜์˜€๊ณ , ๊ณจ๋‹ค๊ณต์ฆ์— ๋Œ€ํ•œ ์˜ํ–ฅ์„ ํ™•์ธํ•˜๊ธฐ ์œ„ํ•œ ๋กœ์ง€์Šคํ‹ฑ ํšŒ๊ท€๋ถ„์„์ค‘ ๋‹จ๊ณ„์  ๋ฐฉ๋ฒ•์— ์˜ํ•œ ๋ถ„์„๊ฒฐ๊ณผ๋Š” ์—ฐ๋ น, ์ž๋…€์ˆ˜, ๋น„๋งŒ๋„, ํ๊ฒฝ, ๋ชจ์œ ์ˆ˜์œ  ๊ทธ๋ฆฌ๊ณ  ๋ชจ๊ณ„์˜ ๊ณจ์ ˆ๋ ฅ์ด ๊ณจ๋‹ค๊ณต์ฆ์— ์˜ํ–ฅ์„ ์ฃผ๋Š” ๋ณ€์ˆ˜๋กœ ์„ ์ • ๋˜์—ˆ๋‹ค. 1. ์—ฌ์„ฑ์˜ ์—ฐ๋ น์ด ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜๋กœ์„œ ์—ฐ๋ น์ด 1์„ธ ์ฆ๊ฐ€ ํ• ์ˆ˜๋ก 1.2๋ฐฐ(1.09-1.35) ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด ๋†’์•˜์œผ๋ฉฐ, ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ ํ•˜์˜€๋‹ค. 2. ์—ฌ์„ฑ์˜ ์ž๋…€์ˆ˜๊ฐ€ ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜์ด๋ฉฐ, ์ž๋…€์ˆ˜๊ฐ€ ๋งŽ์„ ์ˆ˜๋ก ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด 2.0๋ฐฐ(1.25-3.45)๋กœ ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•˜๊ฒŒ ๋†’์•˜๋‹ค. 3. ์—ฌ์„ฑ์˜ ๋น„๋งŒ๋„๊ฐ€ ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜์ด๋‹ค. ๋น„๋งŒ๋„๋Š” ๋†’์„์ˆ˜๋ก 0.8๋ฐฐ(0.69-0.94) ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด ๋‚ฎ์•˜์œผ๋ฉฐ, ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•˜์˜€๋‹ค. 4. ์—ฌ์„ฑ์˜ ํ๊ฒฝ์ด ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜๋กœ์„œ ํ๊ฒฝ๊ธฐํ›„ ์—ฌ์„ฑ์ด 6.8๋ฐฐ(1.23-37.17) ํ๊ฒฝ๊ธฐ์ „ ์—ฌ์„ฑ๋ณด๋‹ค ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•˜๊ฒŒ ๋†’์•˜๋‹ค. 5. ์ˆ˜์œ ๋ฐฉ๋ฒ• ์ค‘์—์„œ ๋ชจ์œ ์ˆ˜์œ ๊ฐ€ ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜์ด๋‹ค. ๋ชจ์œ ์ˆ˜์œ ๋ฅผ ํ•˜๋Š” ์—ฌ์„ฑ์ด 3.0๋ฐฐ(1.13-8.15) ์šฐ์œ ์ˆ˜์œ ๋ฅผ ํ•˜๋Š” ์—ฌ์„ฑ๋ณด๋‹ค ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด ํ†ต๊ณ„์ ์œผ๋กœ ๋†’์•˜๋‹ค. 6. ๋ชจ๊ณ„์˜ ๊ณจ์ ˆ๋ ฅ ์œ ๋ฌด์—์„œ๋Š” ๋ชจ๊ณ„์˜ ๊ณจ์ ˆ๋ ฅ์ด ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋ณ€์ˆ˜์ด๋ฉฐ, ๋ชจ๊ณ„์˜ ๊ณจ์ ˆ์ด ์žˆ์—ˆ๋˜ ์—ฌ์„ฑ์ด 3.8๋ฐฐ(1.11-12.64) ๋ชจ๊ณ„์— ๊ณจ์ ˆ์ด ์—†์—ˆ๋˜ ์—ฌ์„ฑ๋ณด๋‹ค ๊ณจ๋‹ค๊ณต์ฆ์ผ ํ™•๋ฅ ์ด ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•˜๊ฒŒ ๋†’์•˜๋‹ค. ์ด์ƒ์˜ ๊ฒฐ๊ณผ์— ์˜ํ•˜๋ฉด ๊ณจ๋‹ค๊ณต์ฆ ๋ฐœ์ƒ์˜ ์œ„ํ—˜์š”์ธ์œผ๋กœ๋Š” ์—ฐ๋ น์ด ๊ฐ€์žฅ ๋งŽ์€ ์˜ํ–ฅ์„ ์ฃผ์—ˆ๊ณ , ๊ทธ ๋‹ค์Œ์ด ์ž๋…€์ˆ˜, ํ๊ฒฝ, ๋ชจ์œ ์ˆ˜์œ  ๊ทธ๋ฆฌ๊ณ  ๋ชจ๊ณ„์˜ ๊ณจ์ ˆ๋ ฅ์ด๋ฉฐ, ๋น„๋งŒ๋„์—์„œ ๋น„๋งŒ์€ ๊ณจ๋‹ค๊ณต์ฆ์˜ ๋ฐฉ์–ด์š”์ธ์œผ๋กœ ๋ฐํ˜€ ์กŒ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์ƒํ™œ์–‘์‹๊ณผ ๊ด€๋ จ๋œ ์š”์ธ๋“ค์— ๋Œ€ํ•œ ์—ฐ๊ตฌ๊ฒฐ๊ณผ๋Š” ๊ธฐ์กด์˜ ์—ฐ๊ตฌ๋“ค๊ณผ ์ƒ๋ฐ˜ ๋˜์—ˆ์œผ๋‚˜ ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•˜์ง€ ์•Š์•˜๋‹ค. ๊ทธ๋Ÿฌ๋ฏ€๋กœ ์ด๋Ÿฌํ•œ ๊ฒฐ๊ณผ๋ฅผ ํ™•์ธํ•˜๊ณ  ์˜๋ฏธ ์žˆ๋Š” ๊ฒฐ๊ณผ๋ฅผ ์–ป๊ธฐ ์œ„ํ•ด์„œ๋Š” ์žฅ๊ธฐ๊ฐ„์˜ ์ถ”์ ์กฐ์‚ฌ๊ฐ€ ์„ ํ–‰๋˜์–ด์•ผ ํ•  ๊ฒƒ์ด๋‹ค. [์˜๋ฌธ] This study is to examine osteoporosis risk factors of the climacteric women. For the study, survey questionaires were collected among random samples of 425 women who visited general hospitals A,B, and C in Seoul area to get osteoporosis diagnosis during the period of October l-3l, l997. Out of 425 samples, data on the final 25l subjects aged from 40 to 60 years are analysed. The subjects include l09 women from control group and l42 of patient group whose L2-L4 bone density T-scores examined by LUNAR dual energy x-ray obsorptiometry (DEXA) are above -l.0 and below -2.4 respectively. The dependent variable used for the data analysis is osteoporosis while the independent variables include socio-demographic, women's reproductive, genetic factors, and lifestyle factors. Socio- demographic factors are age, weight, height, education, and economic status. Women's reproductive factors include characteristics related to the menopause, the number of siblings, the number of pregnancies, feeding type and anticonceptive pills. The genetic factors are maternal line of bone fractres as well as the subject herself. Finally, the lifestyle factors include drinking of alchohol and coffee, smoking cigarette, calcium intake, exercise and housekeeping. The x2-test and t-test methods of data analysis are utilized to find out the relationships between dependent and independent variables, and the relative risk ratio among the osteporosis risk factors are produced by odds ratio method. The procedures of logistic regression analysis is utilized to confirm key factors out of many relevant factors which cause osteoporosis. The important results of this study are as follow: Statistically significant variables such as age, body mass index, menopause, breast feeding, maternal line of bone fractures, and the number of siblings are chosen and analysed by logistic regression. 1. As age increases by one year, the risk of osteoporosis is increased by l.2 times(l.09-l.35), thus making it statistically significant. 2. The more the number of siblings is, the risk of osteoporosis is doubled (l.25-3.45), thus making it statistically significant. 3. The highter the body mass index of women is, the risk of osteoporosis is 0.8 times lower(0.69-0.94), thus making it statistically significant. 4. The postmenopause women have 6.8 times(l.23-37.l7) higher risk of osteoporosis than the premenopause women, thus making it statistically significant. 5. The women who practice breast feeding have 3.0 times(l.l3-8.l5) higher risk of osteoporosis than the women who do not, thus making it statistically significant. 6. The women who have the maternal line of bone fractures have the 3.8 times (l.ll-l2.64) higher risk of osteoporosis, thus making it statistically significant. The above results show that age is the most important factor among the many risk factors of osteoporosis for women, and the other risk factors are the number of siblings, the degree of body mass index, menopause, breast feeding, and the maternal line of bone fractures in decending order of its significance. In this study, the factors relating to the lifestyle show different results from those of the past studies and did not produce statistically significant results. Therefore, it is necessary that a long term follow up research is required to confirm such results and produce any significant conclusions.restrictio

    ์•Œ๊ณ ๋ฆฌ์ฆ˜ ์ง€๋„ ๋ฐฉํ–ฅ์— ๊ด€ํ•œ ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์ˆ˜ํ•™๊ต์œก๊ณผ,2000.Maste
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