국민학교 소풍장소의 확대방향에 관한 연구 : 한강시민공원 소풍장소 활성화 방안을 사례로

학위논문(석사)--서울대학교 환경대학원 :환경조경학과,1995.Maste

불소 이온 선택적인 화학 반응을 이용한 겔화 물질 개발

Thesis(masters) --서울대학교 대학원 :화학부,2010.2.Maste

BRCA1 과 BRCA1 결합 단백질들의 크로마틴 리모델링에 관련한 기능 연구

Thesis(doctors)--서울대학교 대학원 :생명과학부,2008.2.Docto

The roles of (11)C-acetate PET/CT in predicting tumor differentiation and survival in patients with cerebral glioma

PURPOSE: This prospective study aimed to evaluate the clinical values of (11)C-acetate positron emission tomography/computed tomography (PET/CT) in predicting histologic grades and survival in patients with cerebral glioma. METHODS: Seventy-three patients with surgically confirmed cerebral gliomas (19 grade II, 21 grade III, and 33 grade IV) who underwent (11)C-acetate PET/CT before surgery were included. Tumor-to-choroid plexus ratio (TCR), which was defined as the maximum standardized uptake value (SUV) of tumors to the mean SUV of choroid plexus, was compared between three World Health Organization (WHO) grade groups. Moreover, metabolic tumor volumes (MTV) were calculated. Progression-free survival (PFS) and overall survival (OS) curves were plotted using the Kaplan-Meier method, and differences in survival between groups were assessed using the log-rank test. RESULTS: Median TCR was 1.20 (interquartile range [IQR], 1.14 to 1.4) in grade II, 1.65 (IQR, 1.26 to 1.79) in grade III, and 2.53 (IQR, 1.93 to 3.30) in grade IV gliomas. Significant differences in TCR were seen among the three WHO grade groups (P /= 1.6 than in those with a TCR /= 1 than in those with a TCR < 1. CONCLUSIONS: TCR on (11)C-acetate PET/CT significantly differed between low- and high-grade cerebral gliomas, and it showed the capability to further differentiate grade III from grade IV tumors. TCR and MTV were independent prognostic factors and predicted survival better than did the WHO grade.restrictio