18 research outputs found
๊ฐ์์ ํ์ฑ๊ฐ๋ง๊ฐ ์ธก์ ์ ๋ํ ์ด์ํ์์ฒดํ๋ฏธ๊ฒฝ, ์ฐ๊ฐ๊ฒฝ ๋ฐ ๋น๊ฐ์ญ๋จ์ธต์ดฌ์์ฅ์น์ ๋น๊ต
ํ์๋
ผ๋ฌธ(์์ฌ) -- ์์ธ๋ํ๊ต๋ํ์ : ์์๊ณผ๋ํ ์์ํ๊ณผ, 2022.2. ์๊ฐ๋ฌธ.This study aimed to compare the iridocorneal angle (ICA) measurements of ultrasound biomicroscopy (UBM), spectral domain optical coherence tomography (SD-OCT), and gonioscopy and to demonstrate the inter-device agreement among the three methods to consider the diagnostic value of SD-OCT in the early detection of narrowing ICA.
A total of 29 eyes from 29 client-owned dogs with normal intraocular pressure (IOP) were scanned at the limbus using SD-OCT, UBM, and gonioscopy. ICA and angle opening distance (AOD) were measured from the obtained images of SD-OCT and UBM, and gonioscopy images were analyzed using the ICA grade and ZibWest angle index.
The mean ICA and AOD for SD-OCT and UBM were 28.87 ยฑ 5.78ยบ and 656.94 ยฑ 201.37 ฮผm and 29.00 ยฑ 6.38ยบ and 849.79 ยฑ 257.12 ฮผm, respectively. The mean difference in ICA between SD-OCT and UBM was 0.13o with a 95% limit of agreement (LoA) span of 15.1o, which showed positive agreement, whereas the mean difference in AOD between SD-OCT and UBM was 192.85 ฮผm with a 95% LoA span of 912.21 ฮผm, which showed negative agreement. The Pearson correlation coefficient of the ICA of SD-OCT and ZibWest indices of gonioscopy was 0.574, indicating strong agreement, and the Pearson correlation coefficient of the UBM and gonioscopy was 0.43, indicating moderate agreement.
The inter-device agreements for ICA measurement of SD-OCT, UBM, and gonioscopy were good, such that SD-OCT could be considered an alternative option to screen the narrowing of the filtration angle in clinical settings due to its many benefits, such as the non-contact method and easy handling. Early detection of ICA narrowing may provide information on patients who need early therapeutic interventions.๋ณธ ์ฐ๊ตฌ๋ ์ด์ํ์์ฒดํ๋ฏธ๊ฒฝ(UBM), ๋น๊ฐ์ญ๋จ์ธต์ดฌ์์ฅ์น(SD-OCT), ๊ทธ๋ฆฌ๊ณ ์ฐ๊ฐ๊ฒฝ์ ํตํ์ฌ ๊ฒ์ฌํ ํ์ฑ๊ฐ๋ง๊ฐ์ ์ธก์ ํ๊ณ ๊ฒ์ฌ๋ฒ ์ฌ์ด์ ์๊ด์ฑ์ ๋น๊ตํจ์ผ๋ก์จ ์๋์ ์ผ๋ก ์ฌ์ฉํ๊ธฐ ์ฉ์ดํ SD-OCT๊ฐ ๊ฐ์ง๋ ์ง๋จ์ ์์๋ฅผ ํ์ธํ๊ธฐ ์ํ ๊ฒ์ด๋ค.
2021๋
์์ธ๋ํ๊ต ๋๋ฌผ๋ณ์์ ๋ด์ํ ๊ฐ 29๋ง๋ฆฌ์ ์ ์ ์์ ๋์ ๋์์ผ๋ก ์งํํ์๋ค. 19๋ง๋ฆฌ๋ ๋ฐ๋์ชฝ ๋์์ ๋
น๋ด์ฅ ์ง๋จ๋ฐ์ ํ์์์ผ๋ฉฐ 10๋ง๋ฆฌ๋ ์ ์ ๋์ ํ์์๋ค. UBM๊ณผ SD-OCT ์ฅ๋น๋ฅผ ์ด์ฉํ์ฌ ํ์ฑ๊ฐ๋ง๊ฐ(ICA)๊ณผ ๊ฐ๋ฐฉ๊ฐ๊ฑฐ๋ฆฌ(AOD)๋ฅผ ์ธก์ ํ์๊ณ , ์ฐ๊ฐ๊ฒฝ์ ์ด์ฉํ์ฌ ICA ๋ฑ๊ธ ๋ฐ ๊ธฐ์กด ๋ฐฉ์๋ณด๋ค ๋ ์ ๊ตํ ํ๊ฐ๊ฐ ๊ฐ๋ฅํ ZibWest angle index๋ฅผ ๊ณ์ฐํ์๋ค. ๊ฒฐ๊ณผ์ ์ผ๋ก UBM๊ณผ SD-OCT๋ฅผ ํตํด ์ธก์ ํ ICA๋ ์ฐ์ํ ์๊ด์ฑ์ ๊ฐ์ง๋ ๊ฒ์ ํ์ธํ์์ผ๋ฉฐ, ๋ฐ๋๋ก AOD๋ ์๊ด์ฑ์ด ๋งค์ฐ ๋ฎ์ ๊ฒ์ ํ์ธํ์๋ค. SD-OCT์ UBM์ ICA ๊ฐ๊ณผ ์ฐ๊ฐ๊ฒฝ์ ํตํด ๊ณ์ฐํ ZibWest index๋ฅผ ๋น๊ตํ์์ ๋์๋ ์ ์์ ์ธ ์๊ด์ฑ์ ํ์ธํ์๋ค.
์ด์์ ๊ฒฐ๊ณผ๋ก๋ถํฐ ์์ ํ๊ฒฝ์์ SD-OCT๋ ํ์ฑ๊ฐ๋ง๊ฐ์ ๋ณํ๋ฅผ ์กฐ๊ธฐ์ ๋ฏผ๊ฐํ๊ฒ ํ๋จํ ์ ์๋ ๊ฒ์ฌ๋ฒ์ผ๋ก ํ์ฉํ ์ ์์ ๊ฒ์ผ๋ก ์์๋๋ฉฐ, ์ด๋ฅผ ํตํด ํ์์ ๋ฐ๋ผ ์๋ฐฉ์ ์น๋ฃ๋ฅผ ์ ์ ํ ์๊ธฐ์ ์์ํ ์ ์๋๋ก ๊ธฐ์ฌํ ๊ฒ์ผ๋ก ๊ธฐ๋๋๋ค.Introduction - 7
Materials and Methods - 9
1. Animals - 9
2. Imaging procedures - 10
3. Image analyses - 12
4. Statistical analyses - 16
Results - 17
1. Animals - 17
2. Agreement between SD-OCT and UBM - 18
3. Agreement between SD-OCT and gonioscopy - 20
4. Agreement between UBM and gonioscopy - 21
Discussion - 24
Conclusion - 29
References - 30
Abstract in Korean - 35์
๊ฐ์ธํฌ์ ์ํ๊ณผ์ ์์ ๋ค๊นจ๊ฐ ์ ์์ฑ ๋ณ๋ณ๊ณผ ํด๋ ํ ํจ์๊ณ์ ๋ฏธ์น๋ ์ํฅ
ํ์๋
ผ๋ฌธ(์์ฌ)--์์ธ๋ํ๊ต ๋ํ์ :์ํ์์ํ๊ณผ,2003.Maste
๊ฐ์ ์ ์๋๋ ์ง๋จ์ ์ฑ๊ฒฉ, ์ ์ํน์ฑ ๋ฐ ์๋ ๊ฐ
ํ์๋
ผ๋ฌธ(์์ฌ)--์์ธ๋ํ๊ต ๋ํ์ :์ฌ๋ฆฌํ๊ณผ ์ฑ๊ฒฉ์ฌ๋ฆฌํ์ ๊ณต,2005.Maste