57 research outputs found
Analysis on the Elastic Lateral Stiffness under Seismic Action for Palace Structure in the Building Standards of Song Dynasty
中国古代木构架房屋具有良好的抗震性能,其中凝结了长达数千年间古代的建筑工程经验与智慧。这种“干架”结构有别于现代刚接杆系结构,其结构受力分析尚不能直接套用现代框架结构计算方法。已有的研究,通过缩尺模型试验,回归分析,拟合出类似于现代钢筋混凝土框架结构的动力学方程,尚未能揭示出符合古代设计思想及技术水平的基本原理。从古代房屋结构的设计、建造方法入手,探寻其本源的科学原理,一方面可以为古代建筑的安全性能评价找到一般性的方法,另一方面,古为今用,可以为现代工程建设带来新的启迪。 本文在深入研读《营造法式》的基础上,对古代殿堂结构的构造做法、结构特性进行分析归纳,重点关注:木柱与石础的平面直顶连接,...The Chinese ancient timber frame was well known for good seismic performance. The frame was piled up with many well shaped separate wooden blocks, remarkably different from the modern steel frame which made with several hinged bars. According to the studies have been done, yet we hardly know how the ancient structure was designed. Discovering the original design methods may provide us the general ...学位:工程硕士院系专业:建筑与土木工程学院_结构工程学号:2532012115170
On Pragmatic Failure in C-E Dictioanry Translation
作为具有权威性的工具书,汉英词典在翻译和对外汉语教学实践中起着重要作用,而判断一本汉英词典成功与否的关键因素之一是其翻译质量的好坏。 语用学是一门相对较新的语言学分支,在最近几十年得到了快速发展。越来越多的国内外词典学家开始关注语用学原理在词典编纂实践中的运用,然而大部分词典学家所关注的是如何在词典中编排、体现语用信息,却很少从语用学的视角去把握词典翻译的质量。因此,汉英词典的翻译中存在着大量的语用失误。如何避免这些语用失误成为了改善词典翻译的当务之急。因此,本文把语用学与词典翻译相结合,在语用学理论、词典翻译的原则的指导下,运用个案研究的方法,探讨四本汉英词典——《新时代汉英大词典》,《新...As authoritative reference books, Chinese-English dictionaries play an important role in translation practice and other foreign language teaching and learning activities. Among factors that contribute to the success of Chinese-English dictionaries, the quality of translations in them is a key factor. Pragmatics, as a relatively new branch of linguistics, has been developing rapidly in the pas...学位:文学硕士院系专业:外文学院英语语言文学系_英语语言文学学号:20040400
City System Modeling and Analysis under the Dual Economic Structure: Implications to In-situ Urbanization
在D-S(1977)垄断竞争模型、克鲁格曼(1991)中心-外围模型、藤田和克鲁格曼(1995)单中心城市模型以及藤田和森(1997)、藤田、克鲁格曼和森(1999)、阿纳斯和熊(2003,2005)城市体系演化模型的基础上,本文构建了一个二元结构下的城市体系一般均衡模型,以更深入地理解城市集聚的向心力与离心力的来源,为最优城市规模和城市单中心结构的稳定性分析提供理论基础,为我国城市化道路选择提供理论依据。论文主体由三大部分组成:二元结构下城市体系一般均衡模型的建立;理论模型的拓展分析;理论模型的政策含义。 城市体系一般均衡模型的建立:首先参照克鲁格曼、藤田、阿纳斯等著名新经济地理学家和城市...On the basis of the Dixit Stiglitz's (1977) monopolistic competition model, Krugman’s (1991) core-periphery model, Fujita and Krugman's (1995) monocentric model, especially the models of system of cities of Fujita and Mori(1997), Fujita, Krugman and Mori (1999), and Anas and Xiong (2003, 2005), the thesis constructs a general equilibrium model of a system of cities, in order to understand the sou...学位:经济学博士院系专业:经济学院经济系_西方经济学学号:1532009015345
如何提高失业保险金的使用效率:以福建省为例
当前我国处于经济结构调整期,经济增长速度有所下滑,新增就业机会相对有限,劳动者面临较高的失业风险。而同时失业保险金收支不平衡,存在大量闲置。因此,提高失业保险金的使用效率对缓解就业压力和稳定社会环境具有现实意义。文章以福建省失业保险金的使用为例,强调失业保险金的使用必须从原先的事后救济为主转为事先预防与事后救济并重,提出在保持与国家政策原则一致性的基础上,通过扩大补贴范围、调整补贴方向、提高补贴额度、加强政策落实等方式提高失业保险金的使用效率。教育部人文社科重点研究基地重大研究项目(13JJD790025
Study on strengthening method of multi-story masonry structure dwelling house after some base wall torn down for shopping usage
多层混合结构房屋在我国居住房屋中占有相当的比例,临街多层住宅底层“破墙开店“等野改蛮装造成结构安全隐患的现象严重,一旦倒塌将会造成全楼及周边生命财产损失。对于底层“破墙开店“的多层混合结构住宅的加固补救在我国是必须关注的一个重要问题。分析探讨了几种可行的补救加固方法。分析表明,弥补刚度缺失,恢复原结构刚度中心位置十分关键。Multi- story masonry structure buildings take up a considerable proportion of the existing dwelling houses in China.The underlying "tearing down the wall or widening window for shopping usage"caused lots of hazard problems,when the building structures collapse,may lead to serious losses of the lives and properties.So the reinforcement and remedial measures of the danger structures are of great significance.By structural analysis,several feasible reinforcement methods to recover the safety of building are suggested.Among all the methods suggested,that to reset the removed stiffness and to recover the stiffness centre position is of the most important
Chemical Composition of Chinese Pyrola Herb Volatile and the Effects on the Osteoblast Proliferation
目的分析鹿衔草挥发油的化学成分,研究其对体外培养成骨细胞增殖的影响。方法采用水蒸气蒸馏法提取鹿衔草挥发油,GC-MS检测化学成分;鹿衔草挥发油干预成骨细胞系ROS17/2.8后,采用MTT法检测成骨细胞增殖,流式细胞术检测成骨细胞增殖周期,实时荧光定量PCR检测成骨细胞PCNA mRNA表达。结果一定浓度的鹿衔草挥发油能促进成体外培养成骨细胞增殖,处于增殖周期的成骨细胞比例明显增加,且成骨细胞的增殖细胞核抗原(Proliferating Cell Nuclear Antigen,PCNA)mRNA表达显著提高。结论鹿衔草挥发油通过上调PCNA表达,加速成骨细胞增殖周期进程,从而促进成骨细胞增殖。Objective To analyze the chemical composition of Chinese pyrola herb volatile and study its effects on the in vitro cultured osteoblast proliferation. Methods The water vapor distillation was used to extract Chinese pyrola herb volatile and GC- MS was to determine the chemical composition. After intervention of Chinese pyrola herb volatile on ROS17 /2. 8,MTT method was adopted to determine the osteoblast proliferation,the flow cytometry was to determine the osteoblast proliferating cycle and RT- PCR was to determine the expression of PCNA mRNA. Results Chinese pyrola herb volatile of a certain of concentration promoted the proliferation of in vitro cultured osteoblast cells. The percentage of osteoblast cells in the proliferation cycle was increased apparently and the expression of PCNA mRNA was improved significantly. Conclusion Chinese pyrola herb volatile accelerates the progression of osteoblast proliferating cycle through up- regulating PCNA expression so as to accelerate osteoblast proliferation.国家自然科学基金(81473706);; 福州市卫生系统科技计划项目(2013-S-wq10);; 福建省中医药科研项目(wzgs201307
瞬时弹性记录仪检测在脂肪肝筛查中的成功率及可靠性分析
【目的】瞬时弹性记录仪已被各大肝病学会指南推荐为评估肝脏脂肪变性及肝硬度首选的无创检测工具,本研究旨在分析影响其检测成功率及结果可靠性的因素。【方法】2018年中山大学附属第一医院职工体检自愿接受检查且资料完整者共788例,分析年龄、性别、体质指数、腰围、操作者经验等对检测成功率及结果可靠性的影响。【结果】对脂肪肝的检出率高于B超(55.9%vs.39.9%,P<0.001),总体检测失败及结果不可靠率仅为1.4%,检测成功率与性别无关,而随年龄、体质指数及腰围的增加而降低,LSMIQR/Median也随之呈现上升趋势,结果可靠性下降。随着操作次数增加,检测成功率及结果可靠性上升并趋于稳定,同一操作者进行超过300次检测可认为具备熟练操作经验。【结论】瞬时弹性记录仪的有效测量受增龄、体质指数、腰围等因素影响,固定操作者经短期培训后也能够获得很高的检测成功率及可靠的结果
Study of the effect of Strong-bone granules on the differentiation of ROS1728 osteoblasts with silenced ER expression
目的探讨健骨颗粒对成骨细胞中ERalpha介导的TERT信号通路的调控作用。方法采用雌激素受体拮抗剂ICI182780(Faslodex)阻断成; 骨细胞中雌激素受体alpha(ERalpha)的表达,建立ER抑制的大鼠成骨细胞株ROS1728细胞模型,采用酶联免疫吸附法(ELISA)检测成; 骨细胞液中碱性磷酸酶(alkaline phosphatase,ALP) 、骨钙素(osteocalcin,BGP); 、Ⅰ型胶原(collagen I,Col Ⅰ)的含量。采用实时荧光定量SYBR; GREEN法检测ERE、ERalpha、c-MYCmRNA的表达。采用Western Blot检测TERT、ERalpha、c-; MYC蛋白的表达。结果ELISA法检测结果显示:随着干预时间的延长,培养液中的ALP、BGP、ColⅠ的含量逐渐上升。其中对照组3种信号因子的含; 量最高血,雌激素组次之,健骨颗粒组再次之,模型组最低,各组比较差异有统计学意义(P < 0.05),; 4组TERT、ERalpha、c-MYCmRNA及蛋白表达量情况以对照组的蛋白表达含量最高,雌激素组次之,健骨颗粒组再次之,模型组最低。各组比较; 均有统计学意义(P < 0.05); 。结论雌激素介导TERT信号通路及其相关因子与成骨细胞分化的关系密切,而补肾健脾中药健骨颗粒可通过雌激素介导TERT信号通路促进成骨细胞分化。Objective To investigate the effect of Strong-bone granules on the; regulation of TERT signaling pathway mediated by ER alpha in; osteoblasts. Methods The estrogen receptor antagonist ICI182780; (Faslodex) was used to inhibit the expression of ER in osteoblasts and; to establish the ER-silenced model of rat osteoblast cell line ROS1728.; Serum ALP,BGP,and Col I were determined using enzyme-linked; immunosorbent assay. The mRNA expression of ERE,ERalpha,and c-MYC was; determined using real time quantitative SYBR GREEN assay. The protein; expression of ERE,ERalpha,and c-MYC was detected using Western blotting.; Results The results of ELISA showed that the content of ALP,BGP,and Col; in the culture medium increased gradually with the prolonging of; intervention time. The levels were the highest in the control group,then; followed in estrogen group,Strong-bone granules group,and the model; group,and the difference among the groups was significant (P < 0.05).; The mRNA and protein expression of TERT,ER alpha,and c-MYC was the; highest in the control group,then followed in estrogen group,Strong-bone; granules group,and the model group,and the difference among the groups; was significant (P < 0.05). Conclusion The estrogen mediated TERT; signaling pathway and its related factors are closely related to the; differentiation of osteoblasts. Strong-bone granules promote osteoblast; differentiation through estrogen mediated TERT signaling pathway.国家自然科学基金; 福建省卫生厅中医课题; 福州市卫生系统科技项
Preparation and Characterization of Sinter-Resistant RhSm2O3/SiO2 Catalyst and Its Performance for Partial Oxidation of Methane to Syngas
以乙酰丙酮铑(Rh(acac)_3)和乙酰丙酮钐(Sm(acac)_3)为前驱体,用浸渍法制备了Rh/SiO_2和Rh-Sm_2O_3/SiO_; 2催化剂。采用原位红外光谱、热重分析、低温N_2吸附、X射线粉末衍射、高分辨透射电子显微镜、H_2-程序升温还原和X射线光电子能谱等实验技术对催; 化剂的制备过程,比表面积和物相以及Rh与Sm_2O_3间的相互作用进行了表征,并以甲烷部分氧化制合成气为目标反应对催化剂的稳定性进行了考察。研究; 表明:以Rh(acac)_3和Sm(acac)_3为前驱体采用简单的浸渍法即可制备出Rh平均粒径为2.3; nm且具有良好抗烧结性能的Rh-Sm_2O_3/SiO_2催化剂。在浸渍过程中乙酰丙酮化合物通过与SiO_2表面羟基形成氢键而负载于载体表面。S; m(acac)_3在SiO_2表面的单层负载量(质量分数)约为31%,对应于Sm_2O_3的质量分数约为15%,只要Sm(acac)_3的质量分; 数低于这一阈值,均可保证分解后生成的Sm_2O_3以高分散形式负载于SiO_2上,且不会因高温(800; °C)焙烧而团聚。高分散于SiO_2表面的Sm_2O_3与Rh之间存在强的相互作用,可显著提高Rh的分散度,防止其在高温反应条件下烧结,进而使低; Rh负载量的催化剂表现出良好的甲烷部分氧化制合成气反应活性和稳定性。Rh/SiO2 and Rh-Sm2O3/SiO2 catalysts were synthesized by the conventional impregnation method using rhodium acetylacetonate (Rh(acac)(3)) and samarium acetylacetonate (Sm(acac)(3)) as precursors. The preparation and catalytic properties, as well as the interaction between Rh and Sm2O3, were characterized in detail by in situ infrared spectroscopy (IR), thermogravimetric analysis (TG), N-2 physisorption (Brunauer-Emmett-Teller (BET) method), X-ray powder diffraction (XRD), transmission electron microscopy (TEM), temperature-programmed reduction (H-2-TPR) and X-ray photoelectron spectroscopy (XPS). The performance of the catalysts for the partial oxidation of methane (POM) to syngas was also investigated. The results showed that a sinter-resistant Rh-Sm2O3/SiO2 catalyst with an average Rh particle size of similar to 2.3 nm could be synthesized using the conventional impregnation method with Rh(acac)(3) and Sm(acac)(3) as precursors. The surface silanol groups of SiO2 acted as the centers to interact with M(acac)(3) (M=Rh, Sm) molecules when SiO2 was impregnated in the M(acac)(3) solution, leading to the formation of a hydrogen-bonded M(acac)(3) layer on the SiO2 surface. In this experiment, the monolayer coverage of Sm(acac)(3) on the SiO2 surface was equal to a Sm(acac)(3) loading (mass fraction) of approximately 31%, which in turn corresponded to a Sm2O3 loading of approximately 15%. When a Sm(acac)(3)/SiO2 sample with Sm(acac)(3) loading below 31% was heated in air to approximately 360?, the monolayer Sm(acac)(3) species decomposed into highly dispersed Sm2O3 species on the SiO2 surface, which displayed superior stability against sintering at high temperature. No aggregation of the Sm2O3 species was observed even when the sample was heated to 800 degrees C in air. The strong interaction between the highly dispersed Sm2O3 and Rh plays a key role in increasing the dispersion of Rh species in the catalyst and preventing the Rh species from sintering under high temperature conditions. This factor should also be responsible for the superior activity and stability of the Rh-Sm2O3/SiO2 catalyst with extremely low Rh loading for the catalytic partial oxidation of methane to syngas.国家重点基础研究发展规划项目(2013CB933102),国家自然科学基金(21473144,21373168),国家基础科学人才培养基金项目(J1310024)及教育部创新研究团队项目(IRT_14R31)资
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