Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin

Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients. Diagnosis was confirmed by cyst concentration technique in 2 cases. The other 2 cases were clinically, from the rapid improvement of fever, pulmonary infiltrates and hypoxia following a therapeutic trial of high dose sulfamethoxazole-trimethoprim. All patients responded to treatment with high dose sulfamethoxazole-trimethoprim. Three patients survived pneumocystis carinii pneumonia, but i died due to aspergillosis. One patients showed serological evidence of concomitant cytomegalovirus infection

类泛素蛋白及其中文命名

泛素家族包括泛素及类泛素蛋白,约20种成员蛋白.近年来,泛素家族领域取得了迅猛发展,并已与生物学及医学研究的各个领域相互交叉.泛素家族介导的蛋白质降解和细胞自噬机制的发现分别于2004和2016年获得诺贝尔奖.但是,类泛素蛋白并没有统一规范的中文译名. 2018年4月9日在苏州召开的《泛素家族介导的蛋白质降解和细胞自噬》专著的编委会上,部分作者讨论了类泛素蛋白的中文命名问题,并在随后的\"泛素家族、自噬与疾病\"(Ubiquitinfamily,autophagy anddiseases)苏州会议上提出了类泛素蛋白中文翻译草案,此草案在参加该会议的国内学者及海外华人学者间取得了高度共识.冷泉港亚洲\"泛素家族、自噬与疾病\"苏州会议是由美国冷泉港实验室主办、两年一度、面向全球的英文会议.该会议在海内外华人学者中具有广泛影响,因此,参会华人学者的意见具有一定的代表性.本文介绍了10个类别的类泛素蛋白的中文命名,系统总结了它们的结构特点,并比较了参与各种类泛素化修饰的酶和它们的生物学功能.文章由45名从事该领域研究的专家合作撰写,其中包括中国工程院院士1名,相关学者4名,长江学者3名,国家杰出青年科学基金获得者18名和美国知名高校华人教授4名.他们绝大多数是参加编写即将由科学出版社出版的专著《泛素家族介导的蛋白质降解和细胞自噬》的专家

カキ新品種 \u27夕紅\u27

Yubeni\u27 is a new non-astringent cultivar of Japanese persimmon (Diospyros kaki Thunb.) released by the Persimmon and Grape Research Center (presently the Department of Grape and Persimmon Research) of the National Institute of Fruit Tree Science, Akitsu, Hiroshima, Japan, 1997. The fruit is distinguished by its red skin color and excellent eating quality. \u27Yubeni\u27 resulted from the cross \u27Matsumotowase-Fuyu\u27 × \u27F-2\u27 made in 1970. \u27F-2\u27 is a selection from the cross \u27Jiro\u27 × \u27Okugosho\u27. It was primarily selected at Akitsu in 1985, designated as \u27Kaki Akitsu-11\u27, and has been tested using top-grafting technique at 32 locations in 30 prefectures under the fourth persimmon regional trial initiated in 1989. The \u27Yubeni\u27 fruit is flat shaped, weighing on an average of 230-280 g (similar to or little less than \u27Fuyu\u27 fruit), and ripens in mid to late November. The skin is deep reddish orange, having value 8 in the Color Chart for \u27Fuyu\u27 (Yamazaki and Suzuki, 1980, Bull.Fruit Tree Res. Stn. A7:19-44), more reddish than leading commercial cultivars in Japan such as \u27Fuyu\u27, \u27Jiro\u27, \u27Hiratanenashi\u27, \u27Saijo\u27, and \u27Atago\u27. The flesh is moderately fine, and juicy. Soluble solids content in juice is 17.8% in average, little higher than \u27Fuyu\u27. The number of seeds in fruit is few, 0.8 in average. The fruit is of pollination constant and non-astringent type, in which the deastringency in fruit occurs naturally and stably on tree irrespective of the number of seeds contained in fruit when the tree is grown in warm areas. Its adaptable area is similar to \u27Fuyu\u27. The fruit physiological disorder (fruit cracking at calyx end, cracking at stylar end, and skin blackening) is rare, and comparable to \u27Fuyu\u27. Its shelf life is long (about two weeks), similar to \u27Fuyu\u27. The tree is moderately vigorous, and intermediate between upright and spreading in shape. It does not produce male flower. The number of female flowers is less than ‘Fuyu’. The trees treated with flower thinning show little physiological fruit dropping in the early fruit developmental stage in June and July. However, occasional fruit dropping has been observed in some locations in the late fruit developmental stage in August and Septembe

シンシンショウ ト シンダン サ レテ イタ TOLOSA - HUNT ショウコウグン ノ 15 サイ ジョシ

Tolosa-Hunt症候群(THS)は先行する片側眼窩部痛と眼球運動障害を生じ,病態は海綿静脈洞の非特異的炎症性肉芽腫病変と推測されている.発症は年間100万人あたり1人前後で,40歳台の成人に多く小児例は稀である.今回,1カ月続く右眼をえぐられる様な頭痛を主訴とした15歳のTHSを報告する.発症後,各種頭痛薬で改善がなく,各種検査を施行し異常がないため心身症に伴う反復する片頭痛と診断された.当院で脳MRIを施行し右内頸動脈の狭窄を認めTHSと確定診断した.プレドニゾロン(PSL)1?mg/kg/dayを朝1回開始し,翌日頭痛は改善した.以降,半年かけてPSLを漸減し再発はない.Tolosa-Hunt syndrome(THS)is characterized by periorbital pain accompanying opthalmoplegia. The pathogenesis is considered to involve non-specific granulomatous inflammation in the cavernous sinus, and the frequency is around one case per year per million people. Symptoms usually develop in adulthood, and pediatric cases are rare. We report herein a case of THS in a 15-year-old girl whose headache was diagnosed as psychosomatic disease in the early stage of the clinical course. Her chief compliant was headache with strong pain in the right eye, continuing for 1 month. Although several medications were trialed to alleviate headaches, no improvement was achieved. Various physical examinations proved uninformative. Headache was therefore tentatively diagnosed as psychosomatic disease associated with migraine. Brain magnetic resonance imaging in our university hospital revealed strangulation of the internal carotid artery, and headache was diagnosed as confirmed THS. Oral administration of prednisolone was started at 1 mg/kg/day, given once in the morning. Headache improved from the next day. Oral therapy with prednisolone was tapered over the course of 6 months and headache did not recur

How the ICT-based sports event medical support system should work

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