On the Rule of Law in Charles Dickens’s Bleak House

查尔斯•狄更斯的《荒凉山庄》是一部聚焦于大法官庭的法律文本，在法律与文学这一领域享有重要地位。鉴于此，《荒凉山庄》成功地吸引了文学家以及法学家的注意力，这些评论家普遍认为狄更斯创作这部小说意在揭露大法官庭程序的腐败。然而，也正是由于评论主要集中在大法官庭的程序滥用，《荒凉山庄》作为法律文本的深度没有得到全方位的挖掘。 本文致力于从“法治”角度剖析《荒凉山庄》中的法律描写。通过将文本中大法官庭的指导原则与法治的“实质良好”进行对照，将小说中大法官庭的僵化、迁延以及昂贵与法治的“形式良好”进行对照，以及将小说中主要角色之于法律的态度与法治的“普遍遵从”进行对照，本文试图从全新的角度解...Bleak House by Charles Dickens is a legal text with Chancery Court as its focus. It enjoys a significant status in the discipline of law and literature and has aroused the interests of both the literary and legal scholars. Previous criticisms concerning Bleak House are mainly about how the evil of Chancery practice is revealed by Dickens. However, with attention drawn solely to the operation of Ch...学位：文学硕士院系专业：外文学院_英语语言文学学号：1202011115260

Simulations of sedimental transport process In Jiulong River Estuary

摘要 本文利用ROMS（RegionalOceanModelingSystem）建立了九龙江河口三维水动力与泥沙输运数值计算模式。该模式考虑了在海洋潮汐及九龙江径流作用下，九龙江河口悬沙浓度的变化规律和平面分布特征，并对九龙江河口地区的泥沙粒径分布进行了模拟。本文包含3个主要部分：河口区水动力过程的模拟与验证、悬沙过程的模拟以及河口底部粒径分布的模拟。 本文首先进行了九龙江河口水动力的数值模拟，并用实测的潮位、流速流向和盐度观测资料对模型进行验证，对验证结果进行了综合评价。结果表明，模型计算值与观测值吻合良好，该模型适用于近岸港湾地区的数值模拟研究。随后，本文对九龙江河口洪水期间的悬沙进行...Abstract A three-dimensional hydrodynamic model for Jiulong River Estuary was established with the use of ROMS （Regional Ocean Modeling System）. The model simulated the sediment distribution in Jiulong River Estuary under the process of tide and river flow. Then the distribution of median diameter was simulated. The paper contains three major sections: hydrodynamic model, distribution of suspende...学位：理学硕士院系专业：海洋与环境学院环境科学与工程系_环境科学学号：2262007115234

Identification of Plant Resistance Gene with Random Forest

为了解决传统基于同源序列比对的抗性基因识别方法中假阳性高、无法发现新的抗性基因的问题,提出了一种利用随机森林分类器和k-MEAnS聚类降采样方法的抗性基因识别算法。针对目前研究工作中挖掘盲目性大的问题,进行两点改进:引入了随机森林分类器和188维组合特征来进行抗性基因识别,这种基于样本统计学习的方法能够有效地捕捉抗性基因内在特性;对于训练过程中存在的严重类别不平衡现象,使用基于聚类的降采样方法得到了更具代表性的训练集,进一步降低了识别误差。实验结果表明,该算法可以有效地进行抗性基因的识别工作,能够对现有实验验证数据进行准确的分类,并在反例集上也获得了较高的精度。The traditional homology sequence alignment based approaches usually have high false positive rate and consequently new resistance genes are difficult to be identified.This paper presents a resistance gene identification approach by applying random forest classifier and K-Means under-sampling method.In order to solve the aimless problem in gene-mining research,two main contributions are provided.Firstly,it introduces random forest and 188 dimension features to identify resistance genes,accordingly the sample statistic learning approach can efficiently capture the internal characteristic of resistance genes.Secondly,it selects a more representative training subset and reduces the identification errors for solving the serious imbalanced classification during the training process.The experimental results indicate that the approach can efficiently identify the resistance genes,not only precisely clas-sifying the existing experimental verified data,but also obtaining high accuracy on the negative sample dataset.国家自然科学基金(60932008;61172098;60871092;61001013);中央高校基本科研业务费专项资金(HIT.ICRST.2010022);高等学校博士学科点专项科研基金(201003446)---

基于组合赋权灰色关联TOPSIS的节水灌溉效益评价

在总结现有研究与评价方法的基础上,建立了节水灌溉综合效益评价指标体系。通过群决策相对熵集结模型确定指标的主观权重,改进熵值法确定指标的客观权重,然后将两者组合最终求得评价指标的权重。对TOPSIS方法与灰色关联决策方法分别作改进,通过引入一个考虑决策者偏好的新的相对贴近度度量方式,对二者有机地结合;构建了基于组合赋权的改进TOPSIS-灰色关联决策模型,并将此模型方法应用在某一地区节水灌溉效益评价的实际问题中,最终得出的评价结果基本与实际情况保持一致,进而验证了本模型与方法的可行性与有效性。贵州省科学技术基金项目(黔科合J字LKLS[2013]32号,黔科合LH字[2015]7618号);;贵州省教育厅高校自然科学研究项目(黔教合KY字[2016]271号,黔孝合KY字[2016]103号,黔教合KY字[2017]260号);贵州省教育厅高校人文社会科学研究项目(2016gh03);;贵州省高等学校教学质量与教学改革项目(GZSJG10977201608,GZSJG10977201603,GZSJG10977201508);;六盘水师范学院自然科学科研计划项目(LPSSY201502,LPSSY201605);六盘水师范学院大学生项目(LPSSYDXS1602,LPS..

Review of studies on the validation of surface currents measured by high-frequency radar

本文对高频地波雷达发展与应用过程中海流的对比验证研究进行了回顾与总结。不同的验证研究采用的对比设备与验证方法有所不同,但都通过海上同步观测对雷达反演的海流进行对比,经统计分析评估二者之间海流观测的差异。这些研究表明,地波雷达反演的海流流速和对比观测的均方差水平在10—20CM·S-1之间,主要来源是对比所用仪器与雷达观测目标之间的差异,仪器和雷达海流的测量误差。In this paper,we reviewed the studies on the validation of surface currents measured by high-frequency(HF) radar in terms of instrument development and application.We compared the HF radar current measurement with the conventional in-situ observations,and made statistic analysis to assess the difference between them.The validation errors of HF radar current data are about 10-20 cm·s-1.The sources of these errors are the inherent differences between the physical character of the measuring target and the observation errors of the conventional instrument and the HF radar.国家海洋局第三海洋研究所基本科研业务费专项资金资助项目(2009009、2009066); 国家自然科学基金项目(40906052

Performance Analysis of Chaotic Spread Spectrum CDMA Systems

【中文文摘】混沌序列在具有很好随机性的同时,一些序列还具有KroneckerDelta自相关和近似正交的互相关特点,因此被认为是实现直序扩谱CDMA系统较理想的扩谱序列之一,成为近年来研究的热点。文中从异步DS-CDMA系统的模型入手,分析影响CDMA系统性能的关键问题,说明混沌扩谱CDMA系统的性能优点。为了实现混沌扩谱CDMA系统的数值仿真与性能验证,以切比雪夫映射产生的混沌序列为例进行混沌扩谱CDMA系统的性能分析,并与基于Gold和Kasami两种序列的传统DS-CDMA系统进行比较。 【英文文摘】Chaotic sequence is considered as a good candidate for spread spectrum sequence in CDMA systems because it is characterized by good randomness, Kronecker Delta autocorrelation and orthogonal crosscorrelation. Through asynchronous CDMA system model, the authors analyze the key points of chaotic spread spectrum CDMA system performances,choose Chebyshev map to instantiate the virtue of chaotic sequences and compare with the classic Gold and Kasami sequences.国家自然科学基金项目(60076015);; 福建省自然科学基金项目(A0010019);; 福建省高新技术项

Suppress HBV by therapeutic vaccine

乙肝预防性疫苗显著减少了乙肝新发感染，但目前全球仍有约2.5亿慢性乙肝感染者，若未得到有效治疗，可能发展为肝癌、肝硬化等终末期肝病并导致死亡。夏宁邵教授团队研究发展了一种新型的B细胞表位嵌合型类病毒颗粒乙肝治疗性疫苗（治疗性蛋白），在多种模型中证实了其对慢性乙肝感染的治疗潜力，为研发治疗慢性乙肝的原创药物提供了新思路。 我校博士后张天英、博士生郭雪染和博士生巫洋涛为该论文共同第一作者，夏宁邵教授、袁权副教授、张军教授为该论文的共同通讯作者。【Abstract】Objective: This study aimed to develop a novel therapeutic vaccine based on a unique B cell epitope and investigate its therapeutic potential against chronic hepatitis B (CHB) in animal models. Methods: A series of peptides and carrier proteins were evaluated in HBV-tolerant mice to obtain an optimized therapeutic molecule. The immunogenicity,therapeutic efficacy and mechanism of the candidate were investigated systematically. Results: Among the HBsAg-aa119-125-containing peptides evaluated in this study, HBsAg-aa113-135 (SEQ13) exhibited the most striking therapeutic effects. A novel immuno-enhanced virus-like particle carrier (CR-T3) derived from the roundleaf bat HBV core antigen (RBHBcAg) was created and used to display SEQ13, forming candidate molecule CR-T3-SEQ13. Multiple copies of SEQ13 displayed on the surface of this particulate antigen promote the induction of a potent anti-HBs antibody response in mice, rabbits and cynomolgus monkeys. Sera and purified polyclonal IgG from the immunized animals neutralized HBV infection in vitro and mediated efficient HBV/HBsAg clearance in the mice. CR-T3-SEQ13-based vaccination induced long-term suppression of HBsAg and HBV DNA in HBV transgenic mice and eradicated the virus completely in hydrodynamic-based HBV carrier mice. The suppressive effects on HBsAg were strongly correlated with the anti-HBs level after vaccination, suggesting that the main mechanism of CR-T3-SEQ13 vaccination therapy was the induction of a SEQ13-specific antibody response that mediated HBV/HBsAg clearance. Conclusions: The novel particulate protein CR-T3-SEQ13 suppressed HBsAg effectively through induction of a humoral immune response in HBV-tolerant mice. This B cell epitope-based therapeutic vaccine may provide a novel immunotherapeutic agent against chronic HBV infection in humans.This work was supported by the National Scientific and Technological Major project (2017ZX10202203-001), the National Natural Science Foundation of China (31730029, 81672023, 81871316 and 81702006) and the Xiamen University President Fund Project (20720160063). 该研究获得了“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项、国家自然科学基金等资助

Research of Statistical Process Control in Quality Control of Tobacco Production

为提高烟草生产质量,基于统计过程控制技术,对烟草生产过程进行优化,以提高卷烟质量。对烟草生产特点进行分析、对制丝、卷包生产数据进行分析,设计数据模型。对数据采集频率进行分析,设计分析模型。采用统计分析和反复迭代相结合方式,对生产过程进行优化。该研究已在某一烟草企业应用实施,验证了该研究的合理性和有效性。</p