恩斯特·迈尔:达尔文的使徒

恩斯特·迈尔是20世纪著名的生物学家,也是罕有的一位对生物学及其相关领域有着深入而全面了解的科学思想大师。他曾在鸟类学、系统分类学、进化生物学以及生物学史学和生物学哲学等许多方面做出巨大贡献,包括发现诸多新物种以及提出生物学物种概念;并在1930-1940年代的进化论综合进程中担任主要设计者,从而为促进当代生物学及其哲学的发展起到了重要的作用

Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis

孤儿受体TR3是立早基因表达的产物，属于类固醇/甲状腺受体超家族成员，参与了细胞增殖、分化与凋亡等生理过程的调控。顺铂是一种化疗药物，广泛使用于睾丸癌、膀胱癌、宫颈癌、肺癌、淋巴癌等肿瘤的治疗。顺铂可通过调控细胞内凋亡相关蛋白，诱导肿瘤细胞凋亡，达到抑制肿瘤生长的目的。 本论文研究表明，顺铂通过激活Chk2活性，诱导其与TR3相互作用，使TR3磷酸化，从而诱导肿瘤细胞凋亡，抑制肠道肿瘤的发生和发展。机理研究显示，Chk2诱导的TR3T88磷酸化可稳定TR3蛋白，提高其蛋白表达水平。另一方面，TR3的磷酸化增强其DNA结合能力，促进TR3结合于BRE和RNF-7启动子的TR3应答元件NBRE，...The nuclear orphan receptor TR3 is a product of an immediate-early gene and belongs to the steroid/thyroid/retinoid nuclear receptor superfamily.TR3 is involved in a variety of biological processes, such as cell proliferation, differentiation and apoptosis. Cisplatin is a chemotherapy drug widely used for the treatment of many malignancies, including testicular, bladder, cervical, ovarian, and lun...学位：理学博士院系专业：生命科学学院生物医学科学系_细胞生物学学号：2162007015383

Reengineering the Installation and Maintenance Service Process of Shaoxing Telecommunications

随着互联网技术与应用的飞速发展，中国电信提出从传统基础网络运营商向综合信息服务提供商转型的战略，在原有语音业务基础上开拓互联网、信息化应用市场，并积极推进品牌客户体系建设，建立品牌服务优势。信息化应用的多样性和复杂性，对电信业务的开发、设计与流程规范提出了新的要求，电信装维服务也从原来最简单的电话装、移、修延伸到品牌客户定制终端、iTV产品安装、宽带故障修复等。而长期以来围绕传统通信业务设计的装维服务流程和业务支撑系统，难以满足客户多样化、个性化的综合信息服务需求，因此有必要对支撑品牌客户服务的新型装维服务流程再造进行深入研究。 本文从企业运营和客户需求出发，在文献研究基础上，通过因果图、排...With the rapid development of internet technology and applications, China telecom proposed the strategy of the transformation from a traditional network carrier to the integrated information service provider, which including expanding the internet and information application market that based on the original voice services, and actively promoting establishing the of brand customer system and telec...学位：工商管理硕士院系专业：管理学院高级经理教育中心（EMBA项目）_高级管理人员工商管理硕士(EMBA)学号：X200615607

The Elevation of Labor Cost on Export Trade of China’s Industrial Sectors——An Empirical Study Based on The Data of 33 Industries

在我国经济增长日趋放缓的背景下，关于转变经济增长方式和我国经济增长驱动力的研究日益引起学术界重视。长期以来我国经济增长主要依靠三驾马车，投资、消费和进出口，其中投资和进出口是我国经济增长的主要驱动力，然而近年来我国内外部环境的改变使得我国出口环境发生很大变化。我国即将步入老龄化时代，劳动力成本逐年上升，我国廉价劳动力优势受到很多新兴经济体的挑战，同时世界经济不稳定使我国出口市场受到很大影响。本文基于这样的背景研究劳动力成本上升对我国出口贸易的影响。 本文运用1999-2012年33个工业行业的出口面板数据和工业行业的年平均工资数据建立计量模型，就劳动力成本上升对我国工业行业出口贸易的影响做了...The economic growth has noticeably slowed down, which is the current overall economic situation in China. It is in this context that research about the achievement of a restructured transformation of the economic growth pattern and the driving force of China’s economic growth have been given priority within academic fields. The development of China has long been droved by three factors: investment...学位：经济学硕士院系专业：经济学院_国际经济学学号：1572012115182

児童の「主体的・対話的で深い学び」を視点とした授業づくり : 学びの過程(指導過程)の工夫改善を通して

The complete implementation of the new course of study in April, 2020 is approaching.In thisrevision, while foreseeing contents and time of a unit and a subject, creating classes in "the deep learning by independent and interactive learning" of the child is demanded. The process of discovering a problem according to a characteristic of subjects and thinking of a solution is emphasized there, and to do the creation based on thought and wish is emphasized, too. In the science, the various things and phenomena of the natural world are the learning objective. Target of learning the science is to understand the various things and phenomena of the natural world and to acquire a basic skill such as observation and experiment and to nourish the love for the nature and develop the attitude of solving a problem independently. The aim of this study is to reconsider the problem-solving process (teaching process) and to devise the teaching process from a viewpoint in "the deep learning by independent and interactive learning"