肝组织活检对非酒精性脂肪性肝病的诊断价值

非酒精性脂肪性肝病(NAFLD)发病率逐年上升,起初通常为无明显症状或有转氨酶升高,严重者可发生不同程度的纤维化,并可发展成肝硬化,部分患者最终发生肝功能衰竭和(或)肝细胞癌。尽管影像学迅速发展正日益取代肝组织活检,但肝组织活检在区分非酒精性单纯性脂肪肝与非酒精性肝炎(NASH)、评判肝脏脂肪病变程度及炎症分期与肝纤维化分级、区分良恶性病变及对治疗反应的评估,仍具有不可替代的作用

Determination of the number of ψ(3686) events taken at BESIII

The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^