Dexmedetomidine Might Exacerbate Acute Kidney Injury, While Midazolam Might Have a Postconditioning Effect: A Rat Model of Lipopolysaccharide-Induced Acute Kidney Injury

日本医科大学博士（医学）2023doctoral thesi

Analysis of Risk Factors of Nosocomial Infection in Patients With Cirrhosis and Nursing Countermeasures of Traditional Chinese Medicine

目的探究肝硬化患者产生医院感染的危险因素,并采用中医预防及护理对策,为临床防控医院感染提供参考。方法收集2014年10月1日—2016年10月31日住院治疗的176例肝硬化患者资料,回顾性分析医院感染产生的危险因素,并总结中医预防及护理对策。结果176例肝硬化患者中有5例发生医院感染,其感染率是2.84%,感染部位主要有三种,即肺部感染、胃肠道及腹腔感染,其中,居于感染部位首位的是肺部感染3例（60%）,其次为肠道感染1例（20%）和腹腔感染1例（20%）。5例感染病例均采样送细菌培养,检出4株病原菌,分别为2株的肺炎克雷伯菌（50%）,1株的大肠埃希菌（25%）,1株金黄色葡萄球菌（25%）。年龄≥55岁,住院时间≥30 d、侵入性操作、预防用药、肝功能评级高、合并肝炎是肝硬化患者发生医院感染的危险因素。结论针对肝硬化患者发生医院感染的危险因素,采取相应的中医预防及护理,增强身体免疫能力,可提高肝硬化患者生活质量,促进疾病恢复。Objective To explore the risk factors of nosocomial infection in patients with cirrhosis, and to take preventive and nursing measures toprovide reference for the clinical prevention and control of nosocomial infection. Methods The data of 176 hospitalized patients with cirrhosis from October 1, 2014 to October 31, 2016 were collected. The risk factors of nosocomial infection were analyzed retrospectively, and the countermeasures of prevention and nursing were also summarized. Results There were 5 cases of nosocomial infection occurred in 176 cases of cirrhosis patients, the infection rate was 2.84%, the main infection sites had three kinds, namely, pulmonary infection, gastrointestinal and abdominal infection. Among them, the first place of infection was pulmonary infection（3 cases,60%）, followed by intestinal infection（1 case,20%） and abdominal cavity infection（1 case,20%）. 5 cases of infection were sampled for bacterial culture. 4 strains of pathogenic bacteria were detected, including2 strains of Klebsiella pneumoniae（50%）, 1 strain of Escherichia coli（25%）, and 1 strain of Staphylococcus aureus（25%）. 55 years of age or older, more than 30 days hospitalization, invasive operation, prophylactic antibiotics use, the liver function rating was high, complicated hepatitis,were the risk factors for nosocomial infection in patients with cirrhosis.Conclusion According to the risk factors of nosocomial infection in patients with cirrhosis, we should take corresponding prevention and care of the traditional Chinese medicine to enhance the ability of body immunity,improve the quality of life of patients with cirrhosis, and promote the recovery of disease

Revival of Kettle-drum Culture of Zhang Nationality and Its enlightenment on Protecting National and Folk Culture

铜鼓文化是壮族人民主要的传统文化形态。铜鼓文化在新时代的复兴是壮族人民在物质生活水平提高后精神风貌的映射, 是民族文化建设和社会主义精神文明建设的有机组成部分, 在民族民间文化的传承与保护方面 很有借鉴意义

Optimization of heat treatment process parameter for nickel-base superalloy X-750by nonlinear ultrasonic nondestructive evaluation method

为了获得更好的材料性能,需要对热处理工艺参数进行精确地优化。非线性超声无损检测技术是一种可以有效表征材料微观结构状态变化的评估方法,可以用来评估、优化热处理工艺参数。利用非线性超声波对热处理后的X-750合金材料进行评估,根据超声传播的非线性响应不同,对材料的性能变化做出判断,并与线性超声检测技术的评估结果进行了对比研究。研究发现经过热处理之后,材料性能显著提高,在其中传播的超声非线性响应则明显下降。材料经过热处理后性能提升越大,其声学非线性响应就会变得越小。根据超声波传播的非线性响应定性评估了3种不同的热处理工艺,明确了最优的镍基高温合金X-750退火工艺参数。研究证实了非线性超声方法的敏感度优于传统的线性超声评估方法,可以对材料的热处理效果进行无损评估,从而对热处理工艺参数进行优化与完善。It is necessary to optimize heat treatment process parameter to achieve better material properties of metallic materials.Nonlinear ultrasonic nondestructive evaluation technology is an effective approach to characterize the material's microstructural change,which can be used to evaluate and optimize heat treatment process by nonlinear ultrasonic waves.Nonlinear ultrasonic method is used to evaluate the heat treated X-750 alloy material.Material properties of specimens after heat treatments are evaluated and predicted by the acoustic nonlinear responses of ultrasonic wave propagation.Conventional linear ultrasonic approaches are also used to make comparisons.It is found that the material properties are significantly improved after heat treatment,and better material properties correspond to less nonlinear response of ultrasound propagation.The qualitative evaluation of three different heat treatment processes for X-750 alloy is provided by ultrasonic nonlinear response in the specimens and shows the optimal heat treatment process for this materials.It can be concluded that the nonlinear acoustic technique can be used to evaluate the heat treatment condition nondestructively and to optimize the process with the improved sensitivity compared with conventional linear ultrasonic approach.国家自然科学基金(51405405); 中央高校基本科研业务费专项资金(20720140511)~

三信道全光纤梳状滤波器输出光谱分析

对于同样信道数的波分复用,采用三信道器件比用两信道器件更为简单。文章对一种能够实现三信道平坦输出的全光纤梳状滤波器的新结构进行了分析,推导了新结构的能量传输表达式,详细讨论了耦合器分光比的改变对滤波特性的影响。结果表明,当组成新结构的光纤干涉臂间的长度差和耦合器分光比取某些定值时,可形成一个复用间隔相等、通带平坦的三信道全光纤梳状滤波器,且波分复用的信道间隔仅仅取决于干涉臂长差的大小

山葡萄砧木对‘黑比诺’葡萄耐旱寒的影响研究

以‘黑比诺’自嫁苗和山葡萄为砧木的嫁接苗为试材,在自然低温胁迫和干旱胁迫条件下,对接穗叶片相对含水量、相对电导率、丙二醛含量、可溶性蛋白和可溶性糖等指标进行了对比。结果表明,干旱胁迫下,与自接苗相比,嫁接苗的叶片相对电导率降低,相对含水量和丙二醛升高;在低温胁迫下,山葡萄嫁接苗的相对电导率降低,丙二醛、可溶性总糖和可溶性蛋白含量均升高。试验初步证明以山葡萄为砧木可提高‘黑比诺’的耐旱性和耐寒性

GaAs基MOEMS波长可调谐滤波器的设计和理论模拟

采用传输矩阵理论和结合悬臂梁的电学一机械模型对GaAs基1.55 μm微光电机械系统(MOEMS)波长可调谐滤波器的光学和电学特性进行了深入的对比分析和研究.结果表明,采用800 nm厚的空气腔可以实现滤波器波长的调谐范围为100 nm,所需最大反向偏压为4 V,波长的调谐速率可以达到1.83 MHZ

Haematococcus halophyllum chloroplast homologous recombination vacant carrier and application thereof

本发明涉及基因工程技术领域，具体涉及一种杜氏盐藻叶绿体同源重组空载体及其应用。载体包括启动子、终止子，所述重组空载体含SEQ ID NO : 1所示碱基序列的上游同源臂和SEQ ID NO : 2所示碱基序列的下游同源臂，同源臂之间插入与至少一个外源基因构成多顺反子结构的SEQ ID NO : 5所示的碱基序列。采用本发明的杜氏盐藻叶绿体稳定表达系统, 可实现多个外源基因在叶绿体中稳定表达

基于单个LED的可见光室内定位系统的实现

为了提高室内定位精度,实现三维定位,文章提出了一种基于单个发光二极管（LED）的室内反向定位系统。该定位系统解决了利用多个LED定位时的干扰问题,其将日常所用的白光LED作为光源,既与实际情况相符,又便于将来推广使用。该定位系统根据接收机接收到的光照度来估算距离,以残差平方和最小为目标函数拟合出最佳回归曲线,再利用三边定位原理以及空间几何关系确定接收机坐标。实验结果表明,在实际应用场景中,该定位系统能够实现准确的室内定位服务