Influences of daily TV viewing and TV game playing on visual acuity in Japanese kindergarten children

本論文では, 幼稚園児におけるテレビ視聴とテレビゲーム遊び行動が子どもの視力に与える影響について, 園児の保護者を対象とした調査に基づいて分析された結果が報告された。1日のテレビ視聴時間は週日よりも休日が, また女児よりも男児の方が長かった。テレビゲーム遊びの経験は男児の方が多かったが, 経験月数は逆に女児が多い傾向にあった。テレビゲーム遊びの頻度及び1回当たりの遊び時間は男児が長かった。テレビ視聴時間と視力の間, テレビゲーム遊びの経験及び時間と視力の間には明確な関係は見出だせなかった。The purpose of the present study was to investigate the influences of daily TV viewing hours and TV game play behaviors on visual acuity in Japanese kindergarten children. A self-completed questionnaire was delivered to the parents of 693 children. The questionnaire contained the questions regarding the daily TV viewing hours, the experiences and amounts of TV game play, their influences on psychosomatic health and developments of children, and attitudes of parents toward these children's behaviors. Of these, 682 had fully completed answers. The results of the study showed that boys viewed TV and played TV game more frequently than girls. Visual acuity of the children did not significantly related to their daily TV viewing hours and to their TV game play behaviors in boys and girls

睡眠相关痛性勃起发病相关风险的评估

目的睡眠相关痛性勃起（SRPE）是一种以夜间睡眠中反复被伴有疼痛的阴茎勃起中断而觉醒为临床特征的罕见睡眠障碍，目前病因尚不明确。本研究目的在于探讨可能相关的危险因素对SRPE的发病的影响。方法通过问卷调查的方式，我们对前来泌尿男科就诊的SRPE患者或非SRPE患者进行信息采集。通过Logistic回归分析评估年龄、职业、每晚睡眠开始时间、每周性交频率、心理状态、勃起功能障碍、慢性前列腺炎病史、前列腺增生病史、腰椎疾病史、中枢神经系统疾病史、 高血压病史、糖尿病病史及家族史等是否为SRPE发病的影响因素。结果290名受试者完成了研究，其中对照组145名，病例组145名。单因素Logistic回归分析发现，慢性前列腺炎病史、脑力劳动、职业、中枢神经系统疾病史、晚睡、性生活频率、焦虑状态可能与SRPE发病相关。将上述因素纳入到多因素回归分析模型中后发现，性生活≥2次/周（OR 95%CI = 0.326（0.179，0.592）及晚睡（24时后入睡）（OR 95%CI = 0.494（0.265，0.918）可能是SRPE的保护因素；慢性前列腺炎史（OR 95%CI = 3.779（2.082，6.859）可能是SRPE的危险因素。然而，中枢神经疾病史、职业影响在多因素分析中的统计学差异不显著。结论：慢性前列腺炎、 焦虑状态可能是SRPE的独立危险因素；性生活≥2次/周及适当地推迟睡眠时间可能是独立保护因素

複雑深在性肝外傷後に遅発性仮性動脈瘤をきたした１例

症例は55歳女性。乗用車運転中の自損事故のため救急搬送された。初診時の造影CT検査で複雑深在性肝損傷（IIIb型）を指摘した。バイタルは安定しており保存的に経過観察入院とした。受傷から６日後のCTで血腫の増大や仮性動脈瘤の指摘はなく、受傷から10日目に退院となった。以後当科外来で経過フォローを行ったが、受傷から43日後のCTで肝A5、A8に仮性動脈瘤が出現したため、血管内治療を行った。鈍的肝外傷後の仮性動脈瘤は遅発性出血の原因となるため、基本的にInterventional radiology (IVR) による治療が必要となる。フォローアップ期間について明確な基準は決まっていないが、受傷から１週間後および４週間後に造影CTでフォローを行うことは妥当であると考えられた

Anti-resonance features of destructive quantum interference in single-molecule thiophene junctions achieved by electrochemical gating

基于单个有机分子来构筑电子器件为电子器件微型化提供潜在技术方案。本研究发展了可集成电化学门控的单分子电子器件测试芯片技术和科学仪器方法，在实验和理论两个层面对具有相消量子干涉效应的噻吩衍生物分子器件的电输运过程进行了电化学调控研究，从而首次在室温下实现了对单分子电子器件中量子干涉效应的反共振现象的直接观测和调控，为制备基于量子干涉效应的新型分子材料和器件提供了全新的设计思路和策略。该研究充分展示了电化学调控技术在信息材料和器件领域的重要应用潜力，也体现了我校固体表面物理化学国家重点实验室在电化学研究和科学仪器研发领域的技术积累，以及面向科学前沿开展交叉学科探索的研究特色。 该研究工作是在洪文晶教授、上海电力大学陈文博教授、英国兰卡斯特大学Colin Lambert教授指导下完成的。化学化工学院博士生白杰和李晓慧为论文的共同第一作者，刘俊扬副研究员、师佳副教授、研究生唐永翔、刘帅、黄晓娟、谭志冰和萨本栋微纳研究院的杨杨副教授等也参与了研究工作。田中群教授和毛秉伟教授为该工作提供了重要指导。【Abstract】Controlling the electrical conductance and in particular the occurrence of quantum interference in single-molecule junctions through gating effects, has potential for the realization of high-performance functional molecular devices. In this work, we used an electrochemically-gated, mechanically-controllable break junction technique to tune the electronic behaviour of thiophene-based molecular junctions that show destructive quantum interference (DQI) features. By varying the voltage applied to the electrochemical gate at room temperature, we reached a conductance minimum that provides direct evidence of charge transport controlled by an anti-resonance arising from DQI. Our molecular system enables conductance tuning close to two orders of magnitude within the non-faradaic potential region, which is significantly higher than that achieved with molecules not showing DQI. Our experimental results, interpreted using quantum transport theory, demonstrate that electrochemical gating is a promising strategy for obtaining improved in-situ control over the electrical performance of interference-based molecular devices.This research was supported by the National Key R&D Program of China (2017YFA0204902), National Natural Science Foundation of China (21722305, 21673195, 21503179, 21703188), the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning, Natural Science Foundation of Shanghai (17ZR1447100), Science and Technology Commission of Shanghai Municipality (14DZ2261000), China Postdoctoral Science Foundation (2017M622060) for funding work in Xiamen. It was also supported by EU Horizon 2020 project QuIET under grant agreement no. 767187EC FP7 ITN ‘MOLESCO’ project no. 606728 and UK EPSRC grants EP/N017188/1 and EP/M014452/1 and Leverhulme Trust (Leverhulme Early Career Fellowships no. ECF-2017-186 and ECF-2018-375) for funding instrumentation used in Lancaster. It was also supported by Hungarian and Czech Academies of Sciences (P2015-107) and Hungarian Research Foundation (OTKA 112034) for funding instrumentation used in Hungary. The authors thank Z.-Q. Tian and B.-W. Mao, Xiamen University, for useful discussions. 该工作获得科技部国家重点研发计划课题（2017YFA0204902），国家自然科学基金委优秀青年科学基金等项目（21722305、21673195、21703188、21503179）以及中国博士后科学基金（2017M622060）等项目的资助，也得到了固体表面物理化学国家重点实验室、能源材料化学协同创新中心的支持

Successful pregnancy and delivery after a vitrified-warmed embryo transfer in a woman with Kallmann syndrome: A case report and literature review

Kallmann syndrome, a congenital disorder of idiopathic hypogonadotropic hypogonadism associated with anosmia, results in infertility because of anovulation. Assisted reproductive technology (ART) is considered when optimal ovulation induction therapy is difficult or when several cycles of ovulation induction therapy do not result in pregnancy. However, evidence is lacking regarding the optimal ART treatment for Kallmann syndrome. We report the case of a 33-year-old woman who successfully achieved pregnancy and delivery after ART treatment. At 29 years old, she was diagnosed with Kallmann syndrome due to hypothalamic amenorrhea and anosmia. At 33 years old, she revisited the hospital, desiring a child after one year of infertility. Due to anovulation, she was treated with gonadotropin therapy, but controlling follicular development was difficult, and thus ART treatment was initiated. The controlled ovarian stimulation (COS) protocol for ART treatment employed gonadotropins, recombinant follicular stimulating hormone/human menopausal gonadotropin plus human chorionic gonadotropin, to promote follicular growth. Four oocytes were retrieved, and two cleaved embryos were vitrified and cryopreserved. After vitrified-warmed embryo transfer of a morula stage embryo in a hormone replacement cycle, pregnancy was achieved but resulted in a miscarriage. A second oocyte retrieval was performed under the same COS; four oocytes were retrieved, and two cleaved embryos were vitrified and cryopreserved. Further, a pregnancy was achieved through the vitrified warmed embryo transfer. At 40 weeks and 6 days of gestation, a baby boy weighing 3,344 g with an Apgar score of 7/8 was delivered vaginally. The mother's postpartum course and neonate were free from adverse events. For women with Kallmann syndrome, ART treatment and selective embryo cryopreservation may be a reasonable and safe option

A CASE OF SOLID-CYSTIC HIDRADENOMA OCCURRING ON THE AXILLA

A case of solid-cystic hidradenoma occurring on the left axilla of an 11-year-old girl is reported. The tumor was hemispherical, covered with nomal skin, and movable to the underlying tissue. Histopathologically the tumor was revealed to be localized in subcutaneous fat tissue and surrounded with thin fibrous connective tissue. The tumor cells consisted of epidermoid cells and clear cells, although the former were dominant. Many tubular structures containing colloidal substance were observed within the tumor

飛騨地域における外傷性肝損傷の検討

【要旨】腹部外傷のなかで予後不良な損傷は鈍的外傷による重症型肝損傷つまり日本外傷学会肝損傷分類の複雑型深在性損傷（以下、Ⅲb型肝損傷）である。飛騨地域における３次救急指定病院である当院で過去10年間に経験した外傷性肝損傷は32例、うちⅢb型肝損傷８例における治療経過と結果を比較し今後の治療戦略の課題を検討する。【対象と結果】2008年３月からの当院における10年間に経験した外傷性肝損傷症例のうち日本外傷学会肝損傷分類に明らかに画像上あてはまる32例を対象に受傷機転、外傷分類、治療法、合併損傷などについて比較検討を行った。症例はⅠb型が６例（％）と最も多く、続いてⅢa型が９例（％）、Ⅲb型が８例（％）であった。受傷機転ではⅢb型の７例が自動車での交通外傷であった。合併損傷は12例（％）に肋骨骨折・外傷性血気胸が認められた。肝損傷自体の合併症は胆汁瘻が６例（21.4％）で最も多く認められた。仮性動脈瘤は２例（7.1％）あり、IVR施行例は５例（17.8％）施行されていた。肝損傷に対しての来院直後の手術は２例のうち１例は術後死亡であった。【考察】緊急手術や来院早期、晩期でのIVR施行によって循環動態の安定化を認めた。肝損傷による直接死亡症例を１例認めたが、地域でのIVR体制などチーム医療が今回の結果に寄与していると考える