天皇家ゆかりの文庫・宝蔵の目録学的研究

京都大学新制・論文博士博士(文学)乙第13594号論文博第674号京都大学大学院文学研究科国史学専攻(主査)教授 吉川 真司, 教授 上島 享, 准教授 三宅 正浩学位規則第4条第2項該当Doctor of LettersKyoto UniversityDGA

ベクトル空間の公理系の一部を欠く集合の構成と同値関係によるベクトル空間化

All mathematicians accept the axioms of vector space. Of course, there are people out there who do not. Some people try to derive the existence of zero element from other axioms. However, we can prove that the existence axiom of zero element is independent of other axioms as all mathematicians would think so. Furthermore, we introduce an equivalence relation to make vector spaces from sets in partial absence of the vector space axioms. We shall show that this equivalence relation has a strange property, and we found that there is a connection between the way of our making vector spaces and the construction of the Grothendieck group

Clinical Characteristics of Insulin-Treated Type 2 Diabetes Patients' Improvement in Glycemic Control by Color Display Method in SMBG: Post Hoc Comparison from the Color IMPACT Study

インスリン治療中の2型糖尿病患者を対象にカラーコードを用いた血糖自己測定（SMBG）の効果を検証したColor IMPACT studyにおいて，測定器画面にカラーコードを用いて測定結果の高低を示した52名のHbA1c変化量をもとに改善群と非改善群の二群に分け，血糖改善に及ぼす効果に関して事後解析を行った．二群間で，年齢，性別，糖尿病罹病期間，SMBG頻度，開始時のHbA1cに差を認めなかった．改善群では，非改善群に比べ運動療法スコアとサポート活用力スコアが有意に改善していた．多重ロジスティック回帰分析では，運動療法スコア変化量とサポート活用力スコア変化量の2項目がHbA1c改善と有意な関連を認めた．SMBG画面にカラーコードで測定結果を表示した場合，測定回数を増やすことなく，患者は運動の機会を増やすが，さらに周囲からのサポートを活用することでHbA1cが改善しやすいことが示された.The Color IMPACT study demonstrated that the color display (CD) method for self-monitoring of blood glucose (SMBG) motivates insulin-treated type 2 diabetes patients to increase their level of physical exercise, although this had no impact on glycemic control. Nevertheless, the HbA1c levels improved in half of the subjects using CD. This analysis evaluated factors affecting improvements in glycemic control according to the CD method. The subjects were divided into two groups: responders and non-responders. The HbA1c levels in the responders were reduced by -0.69±0.09 %, while the HbA1c levels in the non-responders increased by+0.42±0.10 %. This difference in the change of HbA1c was 1.11±0.14 % (95 % CI 0.83 to 1.40 %) (p<0.001). There were no significant differences in the demographic data of the subjects at baseline. The scores on the exercise and support subscale of the questionnaire administered at 24 weeks were significantly increased in the responders compared with those of the non-responders. According to a logistic regression analysis, the changes in the exercise and support scores were identified to be variables for improvement in the HbA1c levels. Our results indicate that the CD method encourages patients to exercise and that glycemic control may be improved when patients access available support. These favorable circumstances of diabetes self-management highlight the benefits of the CD method in SMBG