4 research outputs found

    装炉方式对等高齿热处理畸变一致性的影响研究

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    等高齿作为汽车主减速器的重要零部件之一,其畸变一致性直接影响着齿轮接触区一致性的好坏。为了有利于等高齿热处理畸变一致性的控制,研究了其在不同装炉方式下的齿轮热处理畸变情况。研究表明,边缘位置的主动齿轮畸变量稍大于中心位置;主被动齿轮底层位置畸变一致性明显低于上层和中层位置;稀疏装炉齿轮畸变一致性明显低于密集装炉。同时,改进了被动齿轮装炉料架,为优化热处理工装和提高等高齿热处理畸变一致性提供了依据,对齿轮热处理畸变一致性提高方面提出了一些参考意见

    Behavior changes of rats with syndrome of stagnation of liver qi and spleen deficiency after injecting microcrystalline BDNF in bilateral DG areas and regulation of active fraction of Xiaoyao Powder

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    目的:从行为学角度探讨逍遥散有效部位治疗肝郁脾虚证的调节机制。方法:60只雄性SD大鼠随机等分为5组:正常组、模型组、假手术组、脑源性神经营养因子(BDNF)组、逍遥散组。以21d慢性束缚应激方法塑造大鼠肝郁脾虚证模型,在此基础上,运用脑立体定位仪埋管微量注射BDNF塑造BDNF组。逍遥散组造模方法和BDNF组尽可能相似,突出逍遥散有效部位和BDNF二者干预的可比性,第1、7、14、21天分别比较BDNF组和逍遥散组反映行为变化的各项指标变化趋势是否一致。结果:模型组大鼠逐步呈现肝郁脾虚证表现;假手术组大鼠开始呈现焦躁状态,第14-21天,逐步和模型组行为表现趋同;BDNF组起到干预治疗作用,大鼠焦躁状态得到抑制;逍遥散组大鼠表现自然,逍遥散有效部位起到较好的调节作用。排除了手术创伤等混杂因子,逍遥散组和BDNF组经过21d治疗后穿格数、站立次数、修饰次数变化趋势逐步相似。结论:逍遥散有效部位和BDNF可能有一条作用通路相似,即可能均通过BDNF信号通路来治疗肝郁脾虚证。Objective: To explore the mechanism of active fraction of Xiaoyao Powder in treating rats with syndrome of stagnation of liver qi and spleen deficiency. Methods: Sixty SD male rats were randomly divided into 5 groups as control group, model group, sham-operation group, BDNF group and Xiaoyao Powder group. The rat models with syndrome of stagnation of liver qi and spleen deficiency were established by using method of chronic immobilization stress(CIS) for 21 days. On the basis, rats in BDNF group received injection with microcrystalline BDNF in bilateral DG areas with the help of stereotaxic apparatus. The model establishing methods of Xiaoyao Powder and BDNF groups were as similar as possible, in order to highlight the comparability in intervention between active fraction of Xiaoyao Powder and BDNF. The variation trend of behavior indicators of rats in Xiaoyao Powder group and BDNF group was compared on the 1st, 7th, 14 th, and 21 st day. Results: The symptoms of ‘syndrome of stagnation of liver qi and spleen deficiency' appeared progressively in rats of the model group. Rats in shamoperation group were in anxiety states at the beginning, and the symptoms were basically the same with model group from the 14 th to 21 th day. Anxiety state of rats in BDNF group was inhibited. The behaviors of rats in Xiaoyao Powder group were nature, which showed that active fraction of Xiaoyao Powder could play a good adjustment effect. Eliminating the influence of surgical trauma, the crossing times, standing times, and licking frequency of rats in Xiaoyao Powder group and BDNF group after treating for 21 days were basically the same. Conclusion: From the above results of behaviores, it concludes that there is a similar action pathway between active fraction of Xiaoyao Powder and BDNF, and both might treat syndrome of stagnation of liver qi and spleen deficiency by BDNF signaling pathway.国家自然科学基金青年基金项目(No.81302960)~

    小角度范围内弱束缚核~(17)F弹性散射微分截面的奇异行为(英文)

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    在兰州放射性束流线(RIBLL)上完成了17F/17O+208Pb的弹性散射微分截面角分布测量.分析了17F/17O弹性散射产物微分截面的对数(ln(dσ/dθ))随散射角平方(θ2)的依赖关系.结果表明,在所测量的角度范围内(6°-20°),17O的这一依赖关系可以用一条直线很好地拟合,而17F的这一依赖关系需要两条不同斜率的直线才能拟合.17F数据拟合中的这种斜率改变可能起因于17F的奇异结构.对其他实验组数据的分析支持以上的结论,即在一定的角度范围内,弱束缚核与稳定核相比,弹性散射产物微分截面的对数与散射角平方的依赖关系有明显的差异,这可以作为深入研究“晕核”和“皮核”的一个新探针

    Ziprasidone versus other atypical antipsychotics for schizophrenia

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