On the Evaluation Mechanism of EU Risk Decision-making

风险规制是21世纪行政法学较为前沿的研究课题。风险规制一般包括风险评估、风险管理以及风险交流三方面内容。本文所研究的欧盟风险决策的评价机制，属于风险评估事后层面的范畴。鉴于欧盟在2015年5月19日颁布的《更好规制指引》，该指引开创性的将评价机制作为风险决策过程中独立的分析工具，正式建立其统一、规范的评价机制。本文通过对欧盟委员会相关文件报告的梳理分析，从评价机制的演变过程、法律框架、组织架构、运行程序以及委员会下属各司具体评价实践情况等方面，加深对欧盟风险决策评价机制的认识。 第一章对欧盟风险决策评价机制的历史演变脉络进行梳理。从里斯本战略和可持续发展战略，到《影响评估指引》的颁布及两次修...Risk regulation is the frontier subject of administrative jurisprudence in 21st century. Generally speaking, it composes of risk assessment, risk management and risk communication. The evaluation mechanism of EU risk decision-making studied in this context is belongs to the ex-post risk assessment. As the promulgation of better regulation guidelines in 19th May 2015, the guidelines put the evaluat...学位：法学硕士院系专业：法学院_宪法学与行政法学学号：1362013115016

Design and Implementation of Multi-Platform Interface System for Hotel Product Management and Introduce System

在线旅游业是近十几年来兴起的一个行业。近几年受互联网行业迅速兴起的影响，在线旅游业的业务也呈现飞速发展的态势。为了实现盈利的最大化，各个在线旅游服务商之间开始从竞争转向合作，通过优势产品的共享，实现销量最大化。为了达到这个目的，需要各个服务商之间可以高效准确的实现产品数据共享，最初的通过业务人员手工发送数据的方式已经无法满足日渐增长业务量需求，于是，服务商之间开始考虑通过系统间对接的方式实现数据共享，这样不仅准确性和效率大大提高，实时性也大大增强。甚至，在一些复杂的业务规则约束下的产品价格也能迅速准确地通过系统计算之后对接给对接方，对业务量的提升做出了很大的贡献。 目前，市场上的在线旅游服务...Online travel is an emerging industry, it was greatly affected by the rapid development of Internet. Now, the technology which supports the online travel industry is developing rapidly. To maximize the sales volume, most of the online travel agents (OTAs) are seeking for cooperation rather than combination. The cooperation archived by share the products those have obvious advantage effectively and...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323234

Differential contribution of canonical and non-canonical NLGN3 pathways to early social development and memory performances

富山大学博士（医学）Article富山大学・富生命博甲第160号・李 林煜・2024/03/22・★論文非公開★thesi

Design and Realization of Online Consulting System of Building Material Based on Ajax

随着国内经济的快速发展，基础设施的大力建设和房地产的大开发，推动建材市场和其附加产业链日益繁荣，越来越多人关注建材市场和建材信息。但另一方面，专业性强的建材市场信息瞬息万变，大众消费者甚至行业人士投入大量时间都无法及时得到有效的信息。 根据此需求，采用目前流行的Ajax技术对网上建材在线咨询系统进行设计和开发。项目开发以MicrosoftWindowsServer2003为服务器系统、ApacheServer为Web服务器、MySql为数据库、PHP为开发脚本语言、ZendStudio为IDE集成开发编辑器构建开发环境平台，应用Ajax框架jQuery来开发Ajax应用程序和操作Web的DO...The rapid development of domestic economy、strong construction of infrastructural facilities and exploitation of real estate, which leading the building material market and its additional industry chains to the unprecedented prosperous, and people pay more attention to the information about the building material and market. But on the other hand, because of the fast updated professional building ma...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X200823003

Real-time System Fault Tree Minimal Cut Sets Solving

对于传统系统，实时系统的安全性和可靠性的分析缺乏类似的定量评价方法。故障树分析是已被广泛应用于许多行业的系统可靠性分析方法，然而，由于它的语义表达能力有限，因此不能够在实时系统中进行与复杂顺序依赖和时间约束有关的可靠性分析。文章将故障树的语义进行延伸，使复杂顺序依赖和时间约束可以够被故障树所表示，并使故障树分析方法应用到实时系统中。 但是，故障树的最小割集的不能由传统方法求解在延伸语义之后。针对此问题，文章采用时间自动机对实时系统的故障树进行建模，并在其基础上使用模型检验的方法求解最小割集。验证表明，扩展故障树模型后，模型检验得出时间自动机的最小割集可以适用于实时系统的安全性和可靠性分析。 ...The analysis of the safety and reliability for real-time systems lacks quantitative evaluation methods, which commonly work for traditional systems. The Fault Tree Analysis, a reliability analysis method that has been widely applied to many industry systems, is not considered applicable to reliability analysis for real-time systems, due to its limited expressive capability which is unable to descr...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201223105

能源发展路径和价格变化:经济、环境和能源的综合影响评价

本文建立了测算能源价格变化所带来的经济产出、能源需求和污染物减排效应的理论分析框架,分自然演化情形和约束情形计算未来的能源平均价格变化(包括化石能源和非化石能源),并以此价格变化作为外生冲击,在要素可变投入产出模型的框架下模拟能源价格变化对经济系统、能源需求和污染物排放的影响。以安徽省为例进行了实证分析得到以下主要结论,有约束情形下的能源价格比自然演化情形下高,且差额随年份增加而增加,由能源结构转变和能源价格的上涨造成产出和能源需求比自然演化情形下低。能源价格的增加主要是由可再生能源消费占比增加引起的,发展可再生能源有利于环境改善,对经济发展的不利影响有限。国网安徽省电力公司项目“全球能源互联网背景下安徽省远景能源电力发展路径研究”(15301

Study of the effect of Strong-bone granules on the differentiation of ROS1728 osteoblasts with silenced ER expression

目的探讨健骨颗粒对成骨细胞中ERalpha介导的TERT信号通路的调控作用。方法采用雌激素受体拮抗剂ICI182780(Faslodex)阻断成; 骨细胞中雌激素受体alpha(ERalpha)的表达,建立ER抑制的大鼠成骨细胞株ROS1728细胞模型,采用酶联免疫吸附法(ELISA)检测成; 骨细胞液中碱性磷酸酶(alkaline phosphatase,ALP) 、骨钙素(osteocalcin,BGP); 、Ⅰ型胶原(collagen I,Col Ⅰ)的含量。采用实时荧光定量SYBR; GREEN法检测ERE、ERalpha、c-MYCmRNA的表达。采用Western Blot检测TERT、ERalpha、c-; MYC蛋白的表达。结果ELISA法检测结果显示:随着干预时间的延长,培养液中的ALP、BGP、ColⅠ的含量逐渐上升。其中对照组3种信号因子的含; 量最高血,雌激素组次之,健骨颗粒组再次之,模型组最低,各组比较差异有统计学意义(P < 0.05),; 4组TERT、ERalpha、c-MYCmRNA及蛋白表达量情况以对照组的蛋白表达含量最高,雌激素组次之,健骨颗粒组再次之,模型组最低。各组比较; 均有统计学意义(P < 0.05); 。结论雌激素介导TERT信号通路及其相关因子与成骨细胞分化的关系密切,而补肾健脾中药健骨颗粒可通过雌激素介导TERT信号通路促进成骨细胞分化。Objective To investigate the effect of Strong-bone granules on the; regulation of TERT signaling pathway mediated by ER alpha in; osteoblasts. Methods The estrogen receptor antagonist ICI182780; (Faslodex) was used to inhibit the expression of ER in osteoblasts and; to establish the ER-silenced model of rat osteoblast cell line ROS1728.; Serum ALP,BGP,and Col I were determined using enzyme-linked; immunosorbent assay. The mRNA expression of ERE,ERalpha,and c-MYC was; determined using real time quantitative SYBR GREEN assay. The protein; expression of ERE,ERalpha,and c-MYC was detected using Western blotting.; Results The results of ELISA showed that the content of ALP,BGP,and Col; in the culture medium increased gradually with the prolonging of; intervention time. The levels were the highest in the control group,then; followed in estrogen group,Strong-bone granules group,and the model; group,and the difference among the groups was significant (P < 0.05).; The mRNA and protein expression of TERT,ER alpha,and c-MYC was the; highest in the control group,then followed in estrogen group,Strong-bone; granules group,and the model group,and the difference among the groups; was significant (P < 0.05). Conclusion The estrogen mediated TERT; signaling pathway and its related factors are closely related to the; differentiation of osteoblasts. Strong-bone granules promote osteoblast; differentiation through estrogen mediated TERT signaling pathway.国家自然科学基金; 福建省卫生厅中医课题; 福州市卫生系统科技项