Molecular Imaging of 18F-FDG PET/CT in Radiotherapy for Nasopharyngeal Carcinoma: A Prospective Clinical Study

第一章18F-FDGPET/CT在鼻咽癌临床分期中的应用 目的：比较鼻咽癌患者应用18F-FDGPET/CT分期与常规头颈部CT/MRI分期的差异，探讨18F-FDGPET/CT在鼻咽癌分期中的作用，以及对临床治疗决策的指导意义。 方法：62例病理确诊的鼻咽癌初治患者按前瞻性设计的研究方案入组，治疗前依据常规体检、头颈部CT或/和MRI检查等进行AJCC分期（第6版）；然后行18F-FDGPET/CT检查后再次分期，以治疗后临床疗效和随访6个月以上的结果分析18F-FDGPET/CT对T、N分期的影响。以一致性度量Kappa值进行一致性检验。 结果：18F-FDGPET/CT检测到1例第...Chapter 1 The Effect of 18F-FDG PET/CT in Clinical Staging of Nasopharyngeal Carcinoma Objects: To compare the similarities and differences between computed tomography(CT)/magnetic resonance imaging(MRI) and positron 18F-deoxyglucose positron emission tomography/compute tomography(18F-FDG PET/CT), and research the effect of 18F-FDG PET/CT in the clinical staging of nasopharyngeal carcinoma (NPC)....学位：医学博士院系专业：生命科学学院生物学系_细胞生物学学号：2172008015041

构建我国海洋工程生态补偿机制的可行性与现实困境分析

海洋工程建设对生态环境的影响伴随海洋经济发展而日益加剧,实施海洋工程生态补偿有助于海洋经济可持续发展。在我国实践海洋工程生态补偿具有政策可行性及实践可行性,然而海洋工程生态补偿机制的构建亦面临着法律制度、补偿内容、资金保障、管理体制等方面的现实困境。教育部人文社科项目“发展低碳经济的公共政策执行力研究”(10YJAZH035)的阶段性成

Study on photofermentative hydrogen production and mutagenesis of Rhodobacter azotoformans Y6

光合细菌是一类能进行光合作用的原核生物，它能以有机废物为底物，通过光发酵作用分解有机物产生氢。光合细菌产氢包括光发酵产氢和暗发酵产氢两种方式，光发酵产氢是在固氮酶催化下进行的，暗发酵产氢则是在氢酶催化下进行的。光发酵产氢过程与光合作用、碳代谢、氮代谢密切相关，光合作用为产氢提供还原力，碳代谢为产氢提供质子和电子，固氮酶则直接催化质子还原为氢。 对光合细菌Y6的形态结构、生理生化特性及16SrDNA序进行分析，鉴定该菌株为红细菌属的Rhodobacterazotoformans（固氮红细菌）。以丙酸为底物，对该菌光发酵产氢的特性进行了分析。通过单因素实验和正交实验，确定其最佳产氢条件为：温度3...Hydrogen production (2H++2e-«H2) from organic sewage by photosynthetic bacteria (PSB), a group of archaebacteria, can be classified into photofermentative hydrogen production and dark fermentative hydrogen production. The dark fermentative hydrogen production is mainly catalyzed by hydrogenase. The photofermentative hydrogen production is catalyzed by nitrogenase which associated with photos...学位：理学硕士院系专业：生命科学学院生物化学与生物技术系_微生物学学号：20032603

A Study of Personal Reference Switch Device in Pride and Prejudice from the Perspective of Face Theory

《傲慢与偏见》作为英国文学史上最经典的小说之一，已译为二十五国语言，深深吸引着一代又一代的读者和研究者。现有研究多在刻画人物和探索主题等领域取得瞩目的成就，也不乏学者从语用学角度对其展开研究和探讨。然而，在面子理论框架下对其人称转换的研究似乎仍是片空白，尚不多见。 本文基于布朗与列文森的面子理论，对奥斯丁的《傲慢与偏见》全书对话的人称转换进行详细的分析。本文得出以下结论： 1.通过对奥斯丁的《傲慢与偏见》全书对话的分析，发现了两种人称转换手法，即借代人称转换与交叉人称转换。后者是奥斯丁在这部小说中使用更为频繁的人称转换手法。 2.在布朗与列文森的面子理论框架下，本文认为人称转换是出于面子...Pride and Prejudice, one of the greatest classical novels in English literature, rendered into twenty-five languages, has been fascinating readers and researchers for generations. Many achievements have been obtained in the research fields of, for instance, character-shaping and theme-exploring. Recently, researchers have also begun to apply pragmatic theories to their studies. Yet it is kind of a...学位：文学硕士院系专业：外文学院英语语言文学系_英语语言文学学号：1202007115263

Study of Ocean engineering eco-compensation based on Marine Economy Sustainable Development

中共十八大报告明确指出，要发展海洋经济，建设海洋强国。海洋工程建设作为海洋经济的基础产业，为人类获取资源、向海洋拓展空间创造了可能，但其对所使用海域自然属性可能产生永久性改变，对海洋生态造成深远影响。海洋经济可持续发展对海洋工程提出了更高要求。海洋经济可持续发展既考虑海洋资源环境的承载力，选择恰当模式以实现协调发展，更主张代内和代际的公平分配。这亦是本文的立论基础和研究视角。上个世纪70年代我国开始海洋环境保护工作，并将陆域的一些经验做法移植海上。生态补偿机制因其优势而逐步被纳入海洋工程建设规制的政策工具箱。但目前我国的海洋生态补偿实践仍处于摸索阶段，远未满足实际的需要。 本文选取海洋工程生...According to the report of the 18th CPC national congress, to build up China’s marine power, the country must develop its marine economy. As basic industry of marine economy, ocean engineering construction makes it possible for humans to harvest resources from and expand space to the ocean. However, it may change the nature of the exploited ocean permanently, leaving profound and lasting impact on...学位：管理学硕士院系专业：公共事务学院_公共政策学号：1392011115039

从我国公共图书馆事业的案例看财政公共性之公共、公用、公益之间的关系

公共财政的本质特征是其财政公共性,其中包含了公共、公用、公益的内涵。正确认识这三者之间的关系对于分析财政公共性具有重要意义。本文将尝试着以我国的公共图书馆事业为例来探讨财政公共性公共、公用、公益之间的关系

Effect of Notch-1 gene uprugulation on AKT-m TOR signal of U251 cell

目的:观察上调Notch-1基因对人胶质瘤U251细胞生学物行为及AKT-m TOR信号通路的影响。方法:采用p NL-NICD慢病毒感染U251细胞,以RT-PCR和Western-Blot检测Notch-1基因mRNA和蛋白的表达,以MTT检测细胞增殖能力,流式细胞术检测细胞周期变化,Transwell实验检测细胞侵袭能力,同时检测Notch-1上调对AKT、m TOR、P70S6K、4Ebp-1蛋白的影响。结果:与对照组比较,NICD慢病毒转染72h后,Notch-1基因mRNA和蛋白表达明显增高(P<0.01);Notch-1上调明显促进U251细胞增殖、侵袭、促进细胞进入S期,增加周期蛋白Cyclin D1、CDK-4的表达,促进AKT、m TOR蛋白磷酸化。结论:上调Notch-1基因促进U251细胞增殖、侵袭,其机制和活化AKT-m TOR通路有关。Objective: To investigate the effect of Notch- 1 gene up- regulation on biological hehaviors of U215 cell and explore its effects on AKT- m TOR signal. Methods: U251 cells were infected with over- expression NICD or control lentivirus,the mRNA and protein expression of Notch- 1 gene were examined with RT- PCR and Western-Blot,the cell proliferation was assayed with MTT,cell cycle was determined by flow cytometry,the effects of Notch- 1gene on U251 cell invasion were studied using matrigel coated Transwell chambers,the effects of Notch- 1 up- gulation on AKT,m TOR,P70S6 K and 4Ebp- 1 protein expression were also analyzed. Results: Compared with the untreated and empty group,after 72 h of infection,the protein and mRNA expression of Notch- 1 increased( P < 0. 05).It was found that up- regulation of Notch- 1 promoted U251 cell growth,invasion and S- phase cells were increased( P < 0. 05). Up- regulation of Notch- 1 promoted Cyclin D1,CDK- 4 protein expression,and p- AKT and p-m TOR also increased in Notch- 1 up- regulated U251 cells. Conclusion: Up- regulation Notch- 1 promotes U251 glioma cell proliferation and invasion,the mechanism was partly through regulating AKT- m TOR signaling.福建省卫生厅青年基金资助项目(编号:2012-2-76

试析我国地方税体系的制度安排

基于财政分权理论、税制构建的基本原则、生态导向的长远要求和我国政府间财政分配的实践,本文提出了对增值税、所得税传统共享税种在征管和收入方面的调整思路,并主张适当保留部分营业税,改造消费税,改排污费为环境税,改革资源税计征方式,改革车辆购置税的征管和房产税征税范围