风湿性心脏病IgG和IgA-补体双特异性免疫复合物的研究

采用捕捉法ElISA，研究64例风湿性心脏病患者的Igg和IgA-补体双特异性免疫复合物（Igg/C3-TCIC和IgA/C3-TCIC）。结果发现，二者的阳性率均为62.5%，与性别、年龄、病程、rf、补体均无明显关系，而与血清Ig有一定关系；Igg/C3-TCIC的阳性率还与风湿活动和反映风湿活动的指标有关。江西省自然科学基

Analysis of Circulating Immune Complexes of Healthy Individuals with Isoelectric Focusing Polyacrymide Gel Electrophoresis

采用等电聚焦电泳和薄层扫描分析法，研究不同年龄组健康人血清免疫复合物。结果发现，各组的蛋白带均仅出现在高PH区，且具有特征基本相同的扫描峰；将其分为3个区域，各组峰面积百分比均为3区＞2区＞1区，进一步比较在同一区域中各组之间的百分比，则出现≤30岁前比例不稳定和≥40岁后比例稳定的现象；采用等级相关检验法证明，3个区域的面积和总面积在各组之间均分别随年龄增大而显著上升。这些结果反映了个体正常发育、发展和衰老过程中免疫反应的若干特征，可作为用于疾病诊断的正常值依据。irculating immune complexes in 8 diFFerent age groups of healthy individuals had been studied by isoelectric Focusing polycrymide gel electrophoresis and thin layer scanning.It was Found that protein bands only existed in high pH area in every group,with a similar characteristic of scanning pattern.When the map was divided into three rangs based on their typical peaks,the percentages were No.3>No.2>No.1 in each group.Comparing these percentages of the same area among diFFerent groups could give the Fact that they were stable beFore>40 year old but<30 year old.Morever,rank correlation analysis showed that the every rang area and whole one all were signiFicantly bigger as age group became older.Our Findings determine the some characteristics of immune response pattern in the process of normally developing,developed and aging individuals.江西省自然科学基

SpeciFic Immune Complexes Related to HBsAg in Patients with Primary Hepatocellular Cancer

采用捕捉法ElISA,检测31例HbV感染指标阳性的原发性肝癌患者血清四类HbSAg特异性免疫复合物。结果表明,各类的阳性率均非常显著低于慢性活动性乙肝和乙肝后肝硬化,而与慢性迁延性乙肝无明显差异。提示患者的免疫抑制程度与慢迁肝基本一致。SpeciFic immune complexes related to HBsAg of 31 cases of primary hepa-tocellular cancer with positive markers of HBV inFection were determined by antibody capture-ELISA methods.It was Found that their positive rates were signiFicantly lower than those of chronic active hepatitis B and liver cirrhosis aFter hepatitis B inFection and were similar to those of chronic persistent hepatitis B.These Findings suggest that the immune status of patients with primary hepatocellular cancer is similar to that of ones with chronic persistent hepatitis B.江西省自然科学基金资助项

RELATIONSHIPS BETWEEN HBsAg/IgM-CIC AND DEGREE of LIVER DAMAGE IN PATIENTS WITH HEPATITIS B VIRUS INFECTIONS

对六类不同临床病型236例乙肝患者的IgM类HbSAg循环免疫复合物（HbSAg/IgM—CIC）阳性率与AlT和肝损害严重性之间的相互关系进行了探讨。结果发现，其阳性率与肝损害严重程度呈正相关，与AlT的关系则取决于临床类型。提示免疫复合物的肝损作用具有临床类型相关性和异质性。The relationships between HBsAg/IgM circulating immune complexes (HBsAg/IgM -CIC)and ALT level and the degree of liver damage were studied in patients inFected with hepatitis B virus.It was Found that the positive rates of the complexes were positively correlated with the degree of liver damage and ALT level in diFFerent clinical types of hepatitis B virus inFection.These Findings suggested that the two Factors of clinical types and immunoglobulin classes are involved in the Function of liver damage of immune complexes.江西省自然科学基

高砷硫金精矿提金研究

广西贵港金精矿含15%～22%As,并含碳、铅等不利于氰化的元素,金直接氰化率8%～36%。采用催化氧化酸浸法预处理后,金氰化率可达92%～98%,氰渣浮选后精矿的金总收率达97%～99%。预氧化工艺在中温自热、低压、低酸操作条件下进行,废渣、废液符合环保要求。多批次小型试验及扩大试验结果表明该工艺技术指标稳定,经济可行

高铁硫化锌精矿催化氧化直接酸浸新工艺的开发及产业化(二)

创新性地提出并完成了100℃、0.4MPa条件下催化氧压浸出高铁锌精矿的探索性实验、系统性条件实验、扩大实验,半工业试验及30t/d规模可行性研究。高铁锌精矿在专有设计的钛复合板高压釜中浸出,Zn浸出率95%,产出S~0240 kg/t矿。处理规模1.5 t/d半工业试验连续稳定运转30天,结果很好,可为云南澜沧江铅矿进行年产万吨电锌厂建设提供设计参数。此外,采用本工艺处理几种高铟高铁锌精矿,100℃氧压浸出时,铟浸出率均可达90%～98.3%

湿法工艺处理多金属银矿扩大试验

针对某以银为主的多金属精矿,在前期氧化氨浸&mdash;氰化工艺小型试验基础上,进行了6kg和30t/d级的扩大试验。结果表明,氨浸渣脱铅率可达到93%,脱铅渣中金氰化率可达到95%以上,当吨矿NaCN用量达到20kg时,银氰化率也可达到97%以上,扩试结果与小试结果基本一致。根据工业试验相关经济核算,3年内可回收成本

加压催化氧化氨浸法处理坪定金矿的研究和新工艺开发

坪定金矿是富金高砷高碳难处理金矿，所含砷化合物为雌黄和（或）雄黄，普通处理工艺金的氰化率较低。针对坪定金矿特点，提出“加压催化氧化氨浸法”，成功地实现了坪定矿中金的有效回收。通过向氨性溶液中加入硫磺使雄黄转化为易溶于氨水中的雌黄，再通过氨水将矿物中的雄黄去除。最后，利用Cu^2＋的催化作用促使砷脱除过程中在金矿表面所形成的不溶性硫膜氧化，便于后续氰化提金的进行。经过该方法处理后的坪定金矿矿石金的氰化率可达到92％以上。由于采用氨性环境，该工艺中所用设备材料都为普通钢材，设备投资小，运行成本低，经济效益高，2年内可实现盈利

加压催化氧化氨浸法处理坪定金矿的研究和新工艺开发

坪定金矿是富金高砷高碳难处理金矿,所含砷化合物为雌黄和(或)雄黄,普通处理工艺金的氰化率较低。针对坪定金矿特点,提出&quot;加压催化氧化氨浸法&quot;,成功地实现了坪定矿中金的有效回收。通过向氨性溶液中加入硫磺使雄黄转化为易溶于氨水中的雌黄,再通过氨水将矿物中的雄黄去除。最后,利用Cu2+的催化作用促使砷脱除过程中在金矿表面所形成的不溶性硫膜氧化,便于后续氰化提金的进行。经过该方法处理后的坪定金矿矿石金的氰化率可达到92%以上。由于采用氨性环境,该工艺中所用设备材料都为普通钢材,设备投资小,运行成本低,经济效益高,2年内可实现盈利