Development of constructing platform for general substation computer simulation and training system——Secondary equipments

变电站是电力系统的重要组成部分，变电站运行人员的岗位操作技能是影响变电站安全运行的重要因素之一[1]。由于电力系统运行的特殊性，运行人员很难在电力系统的正常操作和事故处理中得到充分训练。因此研制变电站仿真培训系统是一项非常重要的工作。目前国内开发的变电站仿真培训系统，一般都是针对具体变电所开发的，由于在基本运行规律下每个地区的变电站有其自身特点，在管理模式和运行经验上都存在差异，因此针对具体变电所的仿真系统通用性差、不易于扩展和维护，变电站仿真培训系统必须实现通用性，才有推广普及和商品化的价值。为此，必须进一步研究变电站仿真培训通用平台。本课题所开发的通用变电站微机仿真培训系统构建平台，可根据...Substation is an important part of power system and the skill of the operators on duty is one of the essential factors to keep it running safely[1]. Because of the speciality of power system running，it is difficult for the operators on duty to get enough training from daily operations and accidents disposal of power system. Thus we believe it will be of great importance and interesting to develop ...学位：工学硕士院系专业：计算机与信息工程学院计算机科学系_计算机应用技术学号：20022801

The Research on the Legal Questions of the Dissidence Registration

异议登记是我国《物权法》中规定的一种不动产登记类型。在不动产登记簿记载可能有误的情况下，其对真实权利人及利害关系人提供一种救济，即通过在不动产登记簿上记载登记异议，排除登记的公信力，从而达到维护真实权利人及利害关系人的目的。 异议登记在我国的理论和实践中发挥着重要的作用。作为登记对象的不动产，其范围甚广，包括土地异议登记和房屋异议登记两种。由于《物权法》中未对土地异议登记和房屋异议登记进行细分，而在之后颁布的《土地登记办法》和《房屋登记办法》中，则对土地异议登记和房屋异议登记进行了比较详细的论述。故而，探讨异议登记法律问题确有必要。 本文以异议登记的内涵为视角，在探究实务问题，诸如异议登记...The dissidence registration is one type of registrations in the Real Right Law of the People's Republic of China. It provides a way of relief for the right holder and the interested parties in the case of the possible errors of the items recorded in the register of the real estate — namely, through records of the dissidence on the register of the real estate, it will reveal the credibility of excl...学位：法学硕士院系专业：法学院法律系_经济法学学号：K20100700

我国会计师事务所的竞争弱势及应对措施

本文就我国注册会计师行业的竞争弱势进行剖析,并有针对性地提出应对措施,以期对提升我国注册会计师行业的竞争力有所裨益

微生物吸附-化学还原法合成金钯纳米线机理研究

采用微生物吸附-化学还原法,以大肠杆菌(ECCs)为模板、十六烷基三甲基溴化铵(CTAB)为保护剂、抗坏血酸(AA)为还原剂制备金钯纳米线(Au-PdNWs),考察不同金钯摩尔比对合成金钯纳米材料的影响,并通过SEM、TEM、XRD等技术进行了表征,研究其形成机理。结果表明,吸附还原作用使ECCs在短时间内还原生成了少量Pd(0)和Au(0),大量的钯离子和金离子聚集在ECCs表面周围;还原剂AA的加入使ECCs表面成为优先成核位点,菌体表面基团与晶核相互作用阻止其迁移;在CTAB的作用下,菌体表面的纳米颗粒逐渐形成链状纳米中间结构,中间结构通过Ostwald熟化作用进一步形成Au-Pd纳米线。通过ECCs和CTAB协同作用,有利于一维纳米结构的生长。福建省教育厅中青年教科研项目(JAT171117);;莆田市工业科技类科研项目(2016G2020

基于电子鼻的慢性胃炎气滞证患者常见病位的口腔呼气气味图谱研究

目的:运用电子鼻探讨慢性胃炎气滞证患者常见病位的口腔呼气气味图谱特征。方法:采用证素辨证的方法,筛选出397例慢性胃炎气滞证患者并判断病位证素,同时运用基于阵列式气体传感器技术的医用电子鼻(EN0l1103-A)采集其口腔呼气的气味图谱,选择气味图谱响应曲线的振幅、斜率作为图谱特征参数,借助分类器算法对慢性胃炎气滞证与非气滞证的口腔呼气气味图谱特征进行模式识别,比较慢性胃炎气滞证患者常见病位的口腔呼气气味图谱特征。结果:慢性胃炎气滞证的主要病位证素分布是胃(91.18%)、脾(38.29%)、肝(23.68%);主要病位为胃、脾胃、肝脾胃、肝胃;采用分类器算法对慢性胃炎气滞证的气味图谱进行模式识别时,运用随机森林算法,对气滞证的准确率可以达到65.85%;病位胃组、脾胃组的气味图谱响应曲线B、C、D、E、F、I、J的振幅均显著低于病位肝脾胃组(P<0.01);病位胃组、脾胃组的气味图谱响应曲线C、D、E、F、I的斜率均显著低于病位肝脾胃组(P<0.01),脾胃组曲线A的斜率低于病位肝脾胃组(P<0.05)。结论:运用电子鼻结合模式识别方法可初步判断慢性胃炎气滞证及其不同病位间的口腔呼气气味差异。国家自然科学基金项目(No.81373552);;福建省自然科学基金项目(No.2014J01362);;福建省中医药科研项目(No.wzpw201313);;福建省教育厅A类项目(No.JA14212);;载人航天领域预先研究项目(No.020104)~

Study on the gene expression profile in the bone tissue in primary osteoporosis with kidney-yang deficiency syndrome

目的通过检测原发性骨质疏松症不同中医证型患者骨组织基因表达谱的差异,探讨原发性骨质疏松症肾阳虚证相关基因的信息学特征。方法随机选择原发性骨质疏松; 症患者,中医辨证分型为肾阳虚证组3例,肾阴虚证组3例,无肾虚证组3例,并选择正常骨密度人群3例设为正常对照组。用人全基因组表达谱芯片检测4组人群; 骨组织基因表达谱,筛选共同的差异表达基因,并对这些差异表达基因进行基因通路等相关功能分析。结果肾阳虚证组与正常对照组、肾阴虚证组、无肾虚证组的差; 异表达基因分别为2631条、3976条、6184条;肾阳虚证组与其他3组比较共同的差异表达基因有1037条。这些差异基因参与补体与凝血级联反应、; Hedgehog、TGF-beta、细胞周期等22条信号通路。结论原发性骨质疏松症肾阳虚证的相关基因主要与免疫调节、TGF-beta、细胞周期等; 信号通路相关。Objective To investigate the characteristics of genes expression; profiles of primary osteoporosis with kidney yang deficiency through; analyzing the gene expression difference with gene micro-array. Methods; Patient with osteoporosis were rand omly divided into kidney-yang; deficiency group (n = 3),kidney-yin deficiency group (n = 3),non-kidney; deficiency group (n = 3),according to the syndrome differentiation of; traditional Chinese medicine. Another 3 people with normal BMD were; selected as normal control. Expression profiles of the bone tissue from; 4 groups were detected to screen differentiated expression genes.; Analysis of pathway and other function among these genes was conducted.; Results The number of differentiated expression genes in kidney-yang; deficiency group were 3976,6184,and 2631,compared to kidney-yin; deficiency,non-kidney deficiency,and normal control group,respectively.; The number of common differentially expressed genes were 1037. These; genes were involved in 22 pathways,including complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle. Conclusion Genes related to kidney-yang deficiency syndrome in; primary osteoporosis are mainly related to complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle.福建省科技厅省属公益类科研院所基本科研专项; 福建省自然科学基金项

Classification method of diabetes based on integration of characteristic classifier

目的:结合医用电子鼻技术,探讨糖尿病患者及其口腔呼气的气味图谱特征。方法:选择180例糖尿病患者和100例健康者,用医用电子鼻采集280例口腔呼气的气味图谱,采用基于数据特征划分的方法,用支持向量机和随机森林集成模型对糖尿病患者进行分类预测。结果:1线性核函数的支持向量机(SVM1)分类结果不是很理想,低于多项式核(SVM2)、径向基函数核(SVM3)和随机森林(RF)3种分类器,说明分类超平面显然是非线性的;2集成分类器对糖尿病患者和健康者的气味图谱特征的识别准确率可达88.04%。结论:基于特征划分的分类器集成方法预测性能明显好于单一分类器,为使用医用电子鼻进行糖尿病诊断分析提供了一种有效手段。Objective: To discuss the proi le features of oral odor of diabetic patients based on medical electronic nose technology. Methods: 180 patients of diabetes and 100 healthy people were selected, and the proi le features of oral odor of 280 volunteers were collected by using medical electronic nose. The classii cation forecasting was carried out on diabetic patients by using support vector machine(SVM) and random forest integration model based on partitioning method of data characteristics. Results: 1The classii cation result of SVM1 was not very good, which was lower than that of SVM2, SVM3 and RF, and the result showed that the classii cation hyperplane is nonlinear. 2The accurate rate of recognition of integrated classii er on diabetic patients and healthy people is 88.04%. Conclusion: The forecasting performance of classii er integration method based on feature division is superior to that of single classii er signii cantly, which provided an ef ective means for the diagnostic analysis of diabetes based on medical electronic nose.国家自然科学基金项目(No.81373552);; 福建省教育厅A类项目(No.JA14212);; 福建工程学院科研启动项目(No.GY-Z12079)~

Correlation between use of social software and high risk behaviors of HIV infection among MSM in Beijing

目的了解北京市男男性行为者（MSM）社交软件的使用与人类免疫缺陷病毒（HIV）感染及其影响因素的相关性,为今后干预工作提供依据。方法 2016年3—5月,由社区小组招募MSM进行问卷调查,同时进行HIV抗体检测。结果共招募215名MSM,回收有效问卷214份。214人的平均年龄为30.8岁;学历在大专及以上者占73.4%;同性恋者占72.4%;84.6%的人主要通过社交软件寻找性伴。214人中确证HIV感染5人,阳性率为2.3%。分析显示,是否使用社交软件、是否使用同性社交软件和是否使用普通人群社交软件均与HIV感染不相关。多因素分析结果显示,受教育程度高、性取向为同性恋的人更多地使用同性社交软件。63.1%被调查者自述曾经在社交软件上了解到艾滋病防治相关知识,但自述了解程度与是否通过社交软件获得相关信息不相关。结论 MSM社交软件的使用与HIV感染情况无关,也没有增加其对艾滋病知识的了解。但可以考虑改进同性社交软件功能,增加艾滋病防治知识内容,对MSM尤其是高学历、自我定位为同性恋的MSM进行艾滋病防治宣传。[Objective] To understand the correlation between the use of social software and human immunodeficiency virus（HIV）infection and its influencing factors among men who have sex with men（MSM）in Beijing,provide the basis for future intervention work.[Methods]From May to March in 2016,MSM was recruited by community groups to carry out a questionnaire survey and HIV antibody of them was detected.[Results]A total of 215 MSM were recruited and 214 valid questionnaires were recovered. The average age of the 214 MSM was 30.8 years old,73.4% had the education level in college and above,the homosexuals accounted for 72.4%,and84.6% of the respondents mainly found sexual partners through the social software. There were 5 cases of confirmed HIV infection among 214 MSM with the positive rate of 2.3%. The analysis revealed that whether the respondents use the social software,the homosexual social software and the general social software were not related to HIV infection. The results of multivariate analysis showed that people with higher educational level and homosexual orientation were more likely to use the homosexual social software. 63.1% of respondents reported that they had been obtained the knowledge of AIDS prevention and control from social software,but the understanding level was not related to whether the relevant information was obtained through social software or not.[Conclusion]The use of social software has no correlation with HIV infection among MSM,and does not increase their knowledge level of AIDS prevention and control. However,it is necessary to improve the function of the homosexual social software and increase the content of AIDS prevention and control knowledge to carry out the AIDS education among MSM,especially those with higher educational level and homosexual orientation

Experimental Study of the Abalone Shell on Cataract induced by Oxidative Stress

目的研究石决明提取物对体外培养的晶状体氧化应激性白内障形成的作用及机制。方法离体培养小鼠晶状体,应用不同浓度的石决明提取物预孵育晶状体24h后,加入1mm过氧化氢,继续培养3小时后恢复正常培养,72小时后观察小鼠晶状体混浊程度,测定晶状体组织培养液中的乳酸脱氢酶(LDH)含量,晶状体组织中还原型谷胱甘肽(GSH)含量及超氧化物歧化酶(SOD)活力。结果石决明提取物在1~2 mg/ml浓度范围内减轻氧化应激造成的晶状体混浊,减少晶状体LDH的释放,提高组织内GSH含量和SOD活力。结论石决明提取物可减轻氧化应激白内障的形成,其作用主要与石决明提取物提高内源性抗氧化系统有关。Objective To study the effect of the abalone shell extract on oxidative stress induced cataract formation and its mechanism in cultured mouse lens in vitro. Methods The cultured mouse lens were pretreated with the abalone shell extract in different concentrations for24 hours,and then 1mm hydrogen peroxide was added and continued incubating for 3 hours,and they were changed to normal culture media.After 72 hours,the opacity of each lens was observed under an anatomical microscope,the content of lactate dehydrogenase( LDH)leakages,the content of the reduced glutathione( GSH) and activity of superoxide dismutase( SOD) in lens tissue were assayed. Results Abalone shell extract in the concentration range of 1 ~ 2 mg / ml reduced the lens opacity caused by oxidative stress,alleviated the release of LDH,and increased GSH content and SOD activity in cultured lens. Conclusion Abalone shell extract can alleviate the oxidative stress induced cataract formation,and this effect is mainly related to its improvement of the endogenous antioxidant system in lens.2012年福建省卫生厅中医药科研专项课题(No.WST201210);; 2013年福建省卫生厅中医药科研专项课题(No.wzhw201302);; 2014年厦门市科技局科技惠民项目课题(No.3502Z20144030