1,968 research outputs found

    NMR-based metabolomic analysis for mechanisms of both protections of HDL and apoA-I mimetic peptide D-4F, and injury of contrast media on endothelial cells

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    细胞代谢组学将高通量检测技术与多种数据分析方法结合,用于揭示细胞内整体、动态的代谢变化,在药物研究中发挥着重要的作用。本论文采用基于1H核磁共振(NMR)的细胞代谢组学方法,探讨与内皮细胞代谢相关的药物作用机制。 研究表明,载脂蛋白A-I(apoA-I)模拟肽D-4F展现出许多与高密度脂蛋白(HDL)相似的内皮保护功能。但是,目前并不清楚D-4F的内皮保护机制是否与HDL完全一样。因此,我们运用基于1HNMR的代谢组学方法,比较HDL和D-4F拮抗氧化型低密度脂蛋白(ox-LDL)诱导的内皮细胞紊乱的保护机制。我们发现ox-LDL不仅抑制内皮细胞的迁移,而且引发内皮细胞的代谢紊乱。这种代谢紊...Cell metabolomics is being used to reveal comprehensive and dynamic metabolic alterations in cells, which integrates high throughput detection technology and several data analysis methods. It plays a vital role in drug research. In this thesis, we conducted nuclear magnetic resonance (NMR)-based cell metabolomic analysis to elucidate the molecular mechanisms underlying the effects of drugs on endo...学位:理学硕士院系专业:化学化工学院_化学生物学学号:2052014115164

    Design and Implementation of Management System for Comprehensive Insurance Sales Based on .NET

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    在信息技术越来越多的应用到金融保险领域的今天,保险领域的很多模式都发生了很大变化。近两年,随着对软件工程专业知识的不断深入学习,结合我所从事的实际工作,自己很希望利用信息技术,研究开发出一套适应新时期保险销售管理的系统,更好的辅助保险公司各级人员融入销售管理,做到提升保险公司销售管理效率,而我也把这作为我硕士研究生论文的选题。 本系统的实现可以让保险公司更高效的利用信息技术进行保险销售管理,将传统的管理与销售进行紧密结合,两者相互促进、相互借鉴,更加符合时代发展的需求。 本论文主要完成以下工作: (1)本选题来自于中国人民财产保险股份有限公司海南分公司销售管理的实际需求,在对海南分公司销...In information technology, more and more applications to the financial and insurance areas today, many models the insurance field have undergone great changes. The past two years, along with software engineering expertise to further their education, combined with practical work that I do, and they are hoping to use information technology, research and development to adapt to a new period of insura...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323192

    Fission life-time calculation using a complex absorbing potential

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    A comparison between the semi-classical approximation and the full quantum calculation with a complex absorbing potential is made with a model of the fission of 258Fm. The potential barrier is obtained with the constrained Skyrme HF+BCS theory. The life-time obtained by the two calculations agree with each other the difference being only by 25%.Comment: 5 pages, 2 figures, Conference proceedings of CNR*15 workshop, Tokyo, October 2015 to be published in EPJ Web of Conference

    Research on the interactive relationship between producer services and manufacturing: A case of Fujian Province

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    随着信息技术的飞速发展,现代制造业已经融入越来越多的生产性服务作为中间投入要素,生产性服务业和制造业之间已经形成唇齿相依的双向互动关系。促进生产性服务业与制造业良好互动关系,有利于推动经济发展方式转变和产业结构的优化升级,也是产业专业化水平和企业竞争力提升的表现。近年来,福建省经济快速发展,综合实力显著增强,但是制造业发展到一定阶段遇到瓶颈,生产性服务业发展滞缓,两者之间良性互动机制尚未形成。因此,本文尝试对福建省生产性服务业与制造业互动发展关系进行实证研究,揭示福建省生产性服务业与制造业互动发展过程中所面临的问题,并提出有针对性的政策建议,为福建省产业结构优化和经济发展提供一些参考。也希望能...Along with the rapid development of information technology, more and more producer services have been used as the intermediate input in modern manufacturing industry. Producer services industry has been in close and mutual relationship with manufacturing industry, which is not only helpful to optimize industrial structure and economic development mode, but also the measurement criteria of industri...学位:经济学硕士院系专业:经济研究所_产业经济学学号:1582010115180

    Analysis of commercial banks' strategies and methods to liquidity risk —— Taking the case of a "bank run" on the BANK OF EAST ASIA

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    流动性风险因其不确定性及破坏力大的特点,一直以来都是商业银行面临的重要风险之一,加强流动性管理也是商业银行经营者所必须面对的重要课题。近年来,对流动性管理的目的、理论和监管等问题,许多人士都进行过深入的探讨。但是,关于商业银行如何应对突发流动性危机事件的实例分析方面的研究则相对较少。 笔者先后供职于国有大型商业银行和外资银行,对流动性风险的认知逐步加深,特别是在亲身经历了2008年由于香港母行遭遇“挤兑”事件而对内地分支机构经营所造成的冲击之后,对这一被业界称为“商业银行最致命的风险”有了进一步真切的体会。 本文通过对东亚银行因受到谣言攻击而遭挤兑事件的整个过程的回顾,揭示了突发流动性危机...Featured with uncertainties and great destruction, liquidity risk has been one of the most important risks facing commercial banks. Therefore, to strengthen liquidity management has also become a key unavoidable issue for commercial banks. In recent years, a number of professionals have been thoroughly exploring into the field of liquidity management, such as its purposes, theories, regulatory iss...学位:会计硕士院系专业:管理学院会计系_会计硕士(MPACC)学号:X200515702

    The countermeasures study of small enterprises financing service in the city commercial banks in china

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    改革开放以来,我国中小企业在国民经济发展中起到了重要的作用,在促进经济发展、推动经济创新方面成为主力军,在推动出口和发展外向型经济方面,起到了举足轻重的作用。在我国经济持续发展中,中小企业融资难问题日益突出。我国大多数中小企业属于劳动密集型企业,经营管理不规范,规模小、数量多,风险相对较高,投资回报稳定,我国是一个以间接融资为主的国家,企业95%以上的资金需求要通过银行获得,由于银行间分工的不同,城市商业银行在解决中小企业融资难方面具有其他金融机构无可比拟的优势,所以银行贷款在解决我国中小企业融资难问题方面具有重要的意义。 全部论文共分五章。第一章是我国中小企业的界定及中小企业融资理论。第二...Since China's reform and opening up especially the turn of this century, the small and medium-sized enterprises (SMEs) in our country have already played an important role not only in promoting the development of national economy and the economic and technological innovation, but also in promoting exports and developing export-oriented economy. But because of institutional factors, difficulty in S...学位:工商管理硕士院系专业:管理学院高级经理教育中心(EMBA项目)_高级管理人员工商管理硕士(EMBA)学号:X20051500

    The Research on the Relationship Between Noncash Working Capital Management、Cash Asset and Firm’s Value:Evidence from China’s Listed Manufacturing Companies

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    营运资本管理是企业短期财务管理中的核心内容,对企业价值创造的能力有重要影响。本文研究了企业的营运资本管理是否是一种收益-风险的动态权衡结果,营运资本管理对企业价值的影响是否会受到企业的终极控制权、所处生命周期阶段等因素影响的问题。本文选取了中国上市制造业企业作为研究对象,将营运资本区分为非现金与现金两种存在形式,从生产管理理论与公司治理理论出发,探究营运资本管理如何对企业价值创造活动产生影响。研究结果表明,企业价值与非现金营运资本是倒U型关系,非现金营运资本管理对企业价值创造存在促进和抑制两种作用。由于国有企业与非国有企业在公司治理方面存在差异,非国有企业价值与非现金营运资本之间是倒U型关系,...Working capital management plays a significant role in short-term financial management, it has an important impact on the ability of creating value for a firm. We could like to know if working capital management is a result of dynamic tradeoff between earning and risk, whether the impact of working capital management is different with different property in ultimately controlling power and differen...学位:资产评估硕士院系专业:经济学院_资产评估学号:1552013115194
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