561 research outputs found
耳内镜下鼓膜大穿孔鼓室成形术及其临床疗效分析
【目的】分析耳内镜下鼓膜大穿孔鼓室成形术的临床疗效。【方法】回顾性分析我科2017年5月至2019年1月间因慢性化脓性中耳炎鼓膜大穿孔行鼓室成形术的110例(115耳)患者,术中清理鼓室病变及重建听骨链,使用耳屏软骨-软骨膜复合体修补鼓膜,并对术前评估为咽鼓管功能不良的患者同期进行咽鼓管球囊扩张术。观察术后鼓膜一期愈合情况及术后3个月时的言语频率平均气导听阈(PTA)及气骨导差(ABG)。【结果】110例(115耳)患者术后鼓膜一期愈合率为95.7%,术后3月时PTA和ABG分别为(25.7±11.8)dBHL和(13.8±6.9)dBHL,与术前相比,PTA明显降低,ABG明显缩小(均P0.05)。【结论】耳内镜下鼓室成形术临床疗效可靠,耳屏软骨-软骨膜复合体是鼓膜大穿孔鼓室成形术可靠的修复材料,值得临床上推广应用。对于咽鼓管功能不良的患者,同期行咽鼓管球囊扩张术可取得良好的临床疗效
Effect of Decrystallization of Cellulose on Adsorbing Cellulase
为探讨解结晶处理提高酶水解效率的机理,对比研究了高结晶度的微晶纤维素(MCC)和低结晶度的解结晶微晶纤维素(D-MCC)对纤维素酶的吸附过程。结果发现:酶吸附平衡后,样品的XPS和FT-IR分析表明纤维素酶通过酶蛋白的氨基(—NH_2)与纤维素分子链上的羟基(—OH)之间以氢键(C—OH…NH)力吸附在MCC上;相同条件下得到的MCC和D-MCC吸附率曲线的差异表明,底物结构的改善比提高温度更能提高酶吸附率;比较纤维素酶对MCC和D-MCC在35℃下的吸附动力学可知,通过降低底物的结晶度可促进酶吸附,刚性结构的MCC更满足准一级动力学的假设,D-MCC表面结构相对松散,其吸附过程需进一步分析,以得到更适合的动力学方程。The cellulase adsorbed and formed enzyme-substrate( ES) compound is a key step in the process of enzymatic hydrolysis. Through the comparison of cellulase adsorbed on two substrates: microcrystalline cellulose( MCC) with high degree of crystallinity and decrystallization microcrystalline cellulose( D-MCC) with low degree of crystallinity,it was found that,in the XPS wide scan patterns of adsorption equilibrium MCC,a new absorption peak of nitrogen element( 399. 06 e V) was observed. The fitting method is adopted to treat the strong peak of XPS-O1 s,and the binding energy of this new peak was only 530. 53 e V. In the infrared absorption range of 3050- 3550 cm~(- 1),the absorption intensity of OH group decreased with extending adsorption time on cellulose. The above results proved that new hydrogen bonds( C—OH…NH) between the protein amino( —NH_2) and cellulose molecule chain( —OH) were generated during the cellulose adsorption process. From the comparison of the adsorption rate curves between MCC and D-MCC,the decrystallization method to improve cellulase adsorption was more effective than enhancing the temperature. From the comparison of adsorption kinetics between MCC and D-MCC at 35℃,it was indicated that a reduction of cellulose crystallinity was positive for adsorption rate. MCC with rigid surface was fit for the first-order kinetic hypothesis. D-MCC with flexible surface was not suitable for the first-order kinetic. A more suitable kinetic hypothesis should be investigated in the future.国家自然科学基金-广东自然科学基金联合基金重点项目(U0733001
中国信用缺失问题的合约经济学分析
我国目前的信用缺失问题,从根本上说是一个制度性问题。要改变我国的信用现状,就需要重建社会信用体系,不断地促进市场上各种信息的流动和公开,使相关当事人无法通过隐瞒自身信息来获得额外利益,从而实现信息的真实性,实现社会信用水平的改善和提高。It is radically an institutional problem that problem of defects and missing of credit exists at present in China. To change credit status in quo, we need to restructure social credit system and make various information in markets more liquid and more open and make interrelated party unable to obtain additional benefits by holding back information so as to disclose genuine information. In this way, they are made to observe credit and to work honestly, participating in social division of labor, therefore bringing about the improvement of social credit degree.国家教育部博士点人文社会科学研究基金项目(01JB790027
证券市场国际化条件下的法律监管
全球融资证券化和金融市场一体化的发展使各国证券市场国际化的趋势日益加强。如何加强对国际化证券市场的法律监管已成为我国当前证券市场亟需解决的问题之一。本文在纵观我国证券市场国际化的现状后,通过对全球在加强国际化证券市场的法律监管方面的透视,指出我国今后在这方面的努力方
性别视角下的迪士尼改编《木兰》之考辨
好莱坞迪士尼公司致力打造公主系列动画及真人电影,从早期的柔弱无力、等待拯救的白雪公主到拥有魔法、姐妹互救的冰雪女王,构建了一系列女性形象及性别关系,其中便有取材于中国故事的《木兰》。该片经历了从动画版到真人版的改编,除了全球性娱乐商业价值之外,还需要辨析的是,迪士尼公司是如何吸纳并改编基于中国古代男权话语体系的花木兰传奇,其话语策略所产生的利弊效果以及所带来的启示,这将有助于我们运用传统文化资源进行性别新文化话语的建构
自融资交易策略、复制资产组合和风险管理
衍生金融工具是进行风险管理的一个有效工具,但由于我国尚未有金融衍生产品市场,股票指数期货还在建设当中,因此使得投资者的风险管理面临着工具限制。但是,利用BS计算期权定价公式中的复制资产组合的方法,可以利用现有的资产,如股票、债券、无风险资产等,组成一个与金融衍生工具具备相同功能的组合,从而实现有效的风险管理。Financial derivatives are an efficient instrument for risk management, however, there is no financial derivatives market in China and stock index futures is still in construction, hence investors have to confront with instrument limits in risk managemment. But, its advisable to take good advantage of assets available at present, such as stocks, bonds, no-risk-bearing assets, etc. , exploiting the method to duplicate assets portfolio using BS option pricing formula, to make up a portfolio with the same function as financial derivatives , so as to realize effective risk management.国家教育部博士点人文社会科学研究基金项目(01JB790027
我国私募股权基金退出方式偏好与障碍分析
私募股权基金应保持资产的流动性,对于采取何种方式退出,将直接影响私募股权基金的业绩。IPO和并购是我国私募股权基金的主要退出方式。文章认为,我国私募股权退出的障碍有:缺乏完善的法规与政策体系、资本市场体系发育不全、缺乏高效的中介组织体系。文章针对性地提出完善我国私募股权基金退出机制的政策建议
近代中国的文化困境与文化使命——从近代中国文人之死看中国文化
在历史文化语境的不断变换中,人之现世生存的价值问题,濒临价值的凌乱与虚无生命何往的问题仍一次次以中国近代文人自杀的形式提示着它们的存在。中国传统文化确乎到了认真思考自己现代使命的关头。仅就在世价值信念看,时下热闹的现代性与后现代性思潮都难以成为汉语思想真正的现代使命。把个我的在世性价值交付给现代性授权的权威,人固然有了一个庄严的归属,却也不堪其重,在深重的压抑感中,人们呼求自由。在后现代生活空间里,人以肉感的沉醉取消价值追寻的高蹈,卸下满身的重荷狂歌曼舞却时感悬着浮游的恐惧、无家可归的冰冷,又无法不在无法承受之轻中渴慕归属。中国文化的现代使命既不是思考如何禀有提供现世沉重的权柄,也不是探求如何使人置身失重的游戏空间,而是为现世提供一个足可承负人的在体性裂伤,足可抱慰徘徊在价值虚无的边际孤苦无告的灵魂的真实价值信恃
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