Study on Surface Modification of Biomaterials and

在生理环境中，植入材料与机体组织之间的相互作用总是发生在材料表面。材料表面的物理化学特性必然直接影响到组织的愈合，同时，机体环境也可作用于材料表面，并使之发生腐蚀、降解及变性。植入材料的生物相容性和生物活性与表面理化特性密切相关。因此，控制和改善生物材料的表面特性，是促进材料表面与生物体之间相互作用，提高植入材料生物相容性和生物活性的有效途径。由于医用钛及其合金的结构和性质与自然骨相差很大，加之表面钝态氧化膜的存在，通常不能与骨发生化学键性结合，植入体内后，就被纤维性膜所包围，而与周围的骨组织隔离，从而造成植入治疗的失败。努力发展各种方法对医用钛进行表面改性以提高其生物活性是当前的一个研究热点...In physiological environments, the interactions between implants andcellular tissues mainly take place at the surface of implants. Thephysicochemical properties of surface for the implanting material have a veryclose and direct influence on the recovery of tissues; On the other hand,tissues exert effect on the implants surface, leading to corrosion, degradationor modification. It has been widely a...学位：工学硕士院系专业：化学化工学院材料科学系_材料学学号：20013601

跨国公司21世纪的发展趋势及其对华投资战略研究

外直接投资和全球性经营战略给世界经济带来了深刻的影响，传统的以商品贸易为主的国际经济交往格局已被打破，国际分工逐步深入渗透到产业内部和企业内部，国际投资已经成为最重要的国际经济交往形式，跨国公司成为世界经济的主体，成为全球经济增长的引擎。中国经济20年的改革开放，正以不断完善的投资环境和强劲的经济增长势头，吸引着越来越多的跨国公司来华投资。本文希望通过对跨国公司发展趋势及其对华投资战略的研究，促使我国更好地吸引外资，并借鉴它们的成功经验，发展自己的跨国公司。 本文分为三个部分。第一部分主要论述了跨国公司与世界经济发展的关系。跨国公司是世界经济发展的产物，而跨国公司的发展又推动了世界经济的进一...学位：经济学硕士院系专业：经济学院经济研究所_世界经济学号：19970900

A Legal Research on the Transfer of Real Estate Project by Company Equity Restructuring

以公司股权重组的方式实现房地产项目转让的行为已经十分普遍。这种行为表面上符合公司法股权转让规定，实质上涉及到土地使用权转让的的合法性尚有待探讨。因而可以说，以公司股权重组方式实现房地产项目转让行为行走在法律的边缘。在阐述该行为盛行的实质原因并对其合法性进行分析的基础上，针对公司法人拟制人格的隐性弊端，笔者认为在立法上应当对“以土地使用权出资入股”和拥有在建项目的房地产公司以及项目公司的股权重组附加一个条件，即符合土地使用权转让的法定条件。The behavior of the real estate project transfer by company equity restructuring has become widespread. This kind of behavior on the surface is accord with equity transfer provisions of the company law,but the legitimacy of which still needs to be discussed because of it involves the transfer of land use right. In other word, realization by the equity restructuring of real estate projects in the t...学位：法律硕士院系专业：法学院法律系_法律硕士(JM)学号：X200812015

Design and Implementation of Business Management System for the Education and Training Center

随着经济全球化和服务国际化的发展，社会民办教育培训机构逐渐走向市场化。社会民办教育培训机构地不断发展壮大，要求各教育培训机构实施专业化、标准化的管理模式。但是目前各培训机构的管理还停留在原始的纸质记录或使用简单的WPS操作状态，已经无法适应网络信息时代的发展环境，因此要求各教育培训机构自身的运营特点，在信息技术的基础上实现系统化的管理。 针对社会民办教育培训机构的管理需求，本文遵循了现代软件工程的相关思想，结合了主流信息技术，设计一套适应某教育培训中心的业务管理系统。系统的主要功能有：客户信息管理功能、课程信息管理功能及费用信息管理功能。 围绕系统的研发，论文的主要内容包括： 1、对系统...Under the economic developed rapidly in a globalization and international trend, education has gradually been a market industry. Some statistical data show that in the current medium-sized cities, about 85％of the primary and secondary students have received some kinds of extra education and training after class. The education and training institutions have a rapid growth more than rate of 30％every...学位：工程硕士院系专业：软件学院_软件工程学号：X201223123

Advances in the Study of Carbon Nanotube-Polymer Composites

通讯联系人　e-mail :cjlin @xmu. edu. cn[中文文摘]本文综述了两类碳纳米管 聚合物复合材料的制备方法 ,碳纳米管 复合材料的力学、光、电化学等性质 ,以及当前研究的焦点和存在的问题 ,侧重讨论碳纳米管与聚合物相互作用的机理 ,并展望两类复合材料的应用前景.[英文文摘]　A review on the fabrication and the properties of two types of carbon nanotube-polymer composites , such as the mechanical properties , nonlinear optical properties and conductibility is given in this paper. The study focus ,as well as the defects about the composites have been mentioned. The interaction mechanism of carbon nanotubes-polymers is discussed and the application prospect of two types of composites is envisaged.国家自然科学基金资助项目 (No .2 0 12 73 0 2

Surface Biochemical Modification for the Titanium Implants

综述近年来钛植入体表面生物化学设计和改性的研究进展,重点介绍植入体表面自组装改性新技术及其在生物医用材料中的应用。This paper reviews the progress in biochemical design and modification for the surfaces of titanium implants in recent years,the emphasis being laid on the introduction of the surface molecular construction, self-assembly technique and its application in biomedical materials

Fibroblast-like synoviocytes from adjuvant arthritis rat were transfected with plasmid over-expressed TIPE2 and its related analysis

目的:通过TIPE2表达质粒转染大鼠佐剂型关节炎(AA)成纤维样滑膜细胞(flS),体外研究AA的发病中TIPE2对dr5介导细胞凋亡的作用。方法:应用MIgr1/TIPE2+/+表达质粒,经脂质体法导入AA-flS细胞中,转染72小时后,荧光显微镜检测质粒自带gfP基因的表达情况确认转染效率,以未作处理的AA-flS为对照组,用半定量逆转录聚合酶链反应(rT-PCr)检测TIPE2 MrnA的表达,用WESTErn blOT法检测TIPE2蛋白的表达变化,MTT法以及流式细胞术检测抗dr5功能性单链抗体zf1对两组细胞生长的影响。结果:成功获得荧光强度90%的TIPE2过表达AA-flS细胞,TIPE2 MrnA及蛋白表达显著提高。抗dr5单链抗体zf1对TIPE2+/+的flS组细胞具有明显生长抑制及凋亡诱导作用,与不作处理的flS组相比差异显著。结论:TIPE2+/+表达质粒明显提升AA-flS的TIPE2蛋白表达水平,TIPE2对dr5介导细胞凋亡有重要作用。Objective: Fibroblast-like synoviocytes from adjuvant arthritis( AA) rat were transfected with plasmid over-ex- pressed TIPE2+ / +,then apoptosis mediated by TIPE2 on DR5 and its pathological role in adjuvant arthritis( AA) were studied in vitro.Methods: The plasmid of MIGR1 / TIPE2+ / +were transfected to AA-FLS by liposome,after 72 h,the expression of GFP gene that plasmid owned was identified by fluorescence microscope in confirm transfection efficiency,TIPE2 mRNA expression was detected by semi-quantitative reverse transcription polymerase chain reaction( RT-PCR),TIPE2 protein expression of AA-FLS were detected by Western blot.The growth resistance of cells mediated by ZF1( DR5 single chain antibody) was detected by MTT method and flow cy- tometry.Results: Plasmid over-expressed TIPE2+ / +were transfected to AA-FLS successfully as the fluorescence intensity reached 90%,TIPE2 mRNA and protein expression were significantly improved.Furthermore,the growth inhibition and apoptosis induction effect on FLS / TIPE2+ / +were significant,compared with FLS without processing.Conclusion: TIPE2 expression level in AA-FLS are significantly improved by transfecting plasmid expressed TIPE2+ / +,TIPE2 plays an important pathological role in apoptosis mediated by DR5.国家自然科学项目基金(81072472); 福建省自然科学项目基金(2012J01416)资

Determination of Microamouts of Ammonia in Meat by Nessler's Reagent Spectrophotometry

本文提出了一种测定肉中粗氨的方法,可用于肉品新鲜度的检验。在常温下,纳氏试剂与肉中粗氨反应生成淡红棕色胶态化合物,最大吸收波长为400nm,表观摩尔吸光系数为1.404×104L/mol·cm,线性方程为y=0.52x+0.0001,r=0.9997,线性范围为0～1.0μg/ml,回收率在97.8%～104.8%之间。A method for the determination of the crude ammonia in meat was presented in this paper. The method based on the color reaction of ammonia-Nessler's Reagent in room temperature. The results showed that the apparent molar absorptivity is 1.404 ×104 L/mol·cm at the wavelength of 400nm. Beer's law is obeyed for the ammonia in the range of 0～1.0 μg/ml. The correlation coefficient is 0.9995. The recovery rate is 97.8%～104.8%. The method has been applied satisfactorily to crude ammonia in meat.福建省科技计划重点项目(2004Y012

皂术茵陈方治疗非酒精性脂肪性肝炎的临床观察及其对肠道菌群的影响

目的评价皂术茵陈方调节肠道菌群治疗非酒精性脂肪性肝炎(NASH)的临床疗效及其作用机制。方法选取福建中医药大学附属厦门市中医院肝病中心门诊就诊的NASH患者80例,采用随机数字表法分为治疗组(40例)和对照组(40例)。治疗组予中药皂术茵陈方治疗,对照组予以枯草杆菌二联活菌肠溶胶囊治疗,两组疗程均为12周。评价治疗前后两组患者的症状、体征积分以及血清ALT、AST活性;检测两组患者血清内毒素水平以及肠道菌群变化。结果治疗12周后,治疗组的临床总有效率达87.5%(35/40),较之对照组的65%(26/40)有统计学意义(χ~2=7.966,P<0.05);两组患者ALT、AST活性以及血清内毒素水平较治疗前均有明显下降(P<0.05),且以治疗组的ALT、AST活性下降值大于对照组(t=2.254,t=2.325,P<0.05);两组患者肠道菌群中的双歧杆菌、乳酸杆菌、拟杆菌数量较治疗前显著升高,而肠球菌、肠杆菌显著降低(P<0.05)。结论皂术茵陈方具有改善肝功能、治疗NASH的临床疗效,其作用机制与调节肠道菌群紊乱、恢复肠道微生态平衡、减轻肠源性内毒素血症相关。国家自然青年科学基金资助项目(No.81503529);;福建中医药大学临床专项校管课题基金(No.XB2016080