全喉切除术后无喉者的语言康复实践

喉癌患者行全喉切除后,由于丧失语言功能,严重影响了其生活、生存质量,积极帮助无喉者使其获得语言康复,既是医疗问题,也是社会问题,我们与香港新声会联合举办语言康复训练班,收到较好的效果,现报告如下.postprin

Study on Vibration Characteristics of Wheeled Tractor Power Output Assembly

通过对大功率轮式拖拉机动力输出总成系统的激励分析、振动模态分析以及对系统固有特性的研究,分析了轴不平行度几何因素对总成系统的振动影响,研究了轴承游隙、轴承预紧力等物理因素对总成系统的固有特性影响。通过将轴承游隙、轴承预紧力控制在一个合理范围内,降低了系统的固有频率,减小了动力输出总成系统的振动。Based on the excitation analysis and vibration modal analysis of a large power wheeled tractor power output assembly system and study of the system intrinsic characteristics,the influence of shaft nonparallelism on assembly system vibration is analyzed. In addition,the influence of physical factors such as bearing clearance and bearing preload on inherent characteristics of the assembly system is studied. By controlling the bearing clearance and bearing preload within a reasonable range,the natural frequency of the system is reduced,and the vibration of the assembly system is also reduced.工信部智能制造专项“新型轮式拖拉机智能制造新模式应用”（豫洛工业制造[2016]07744

A high-pressure extraction technique and its application in seed oil

设计并建立一套适用于植物油萃取的高压工艺的实验装置。在温度为12~24℃、压力约6 MPa时,以高压液体二氧化碳对沾油布条的预萃取实验表明,该装置可以在萃取温度下40 min内将油从布条中几乎萃取完毕。在温度为25~40℃、压力为0.4~1.0 MPa下,采用液化气为萃取剂,考察该工艺对完整颗粒的黄豆和花生中植物油的萃取收率。常压条件下,考察了常规使用的正己烷溶剂于不同萃取温度下对完整颗粒的黄豆和花生中植物油的萃取收率的影响。比较2种萃取方式所得同种原料的对应植物油的萃取收率的结果表明:以正己烷为溶剂,常压萃取对豆油的萃取效果较好,萃取温度在正己烷沸点时效果最佳,豆油的萃取收率达2.88%;以液化气为溶剂,采用高压萃取方式对花生油的萃取效果较好,萃取温度在40℃时,花生油的萃取收率达4.91%。An experimental apparatus for high-pressure extraction of seed oil was designed and established.At 14～24℃ and about 6 MPa the apparatus was applied to a model system:cloth adsorbed with oil;the extraction results showed the oil could be quickly extracted into liquid carbon dioxide within 40 min at different extraction temperature,indicating the availability of the technique.At 25～40℃ and 0.4～1.0 MPa the apparatus was employed to extract seed oil from unbroken soybean and peanut respectively by using liquefied-gas as the extractant.Moreover,the oil extraction from unbroken soybean and peanut were also investigated at atmospheric pressure by using conventional hexane as the extractant.The oil yields obtained from the same material by the two methods were compared and analyzed.Results showed that hexane as solvent for extracting soybean at the boiling point of hexane with the extraction rate of 2.88% was more favorable than liquefied-gas implemented at high pressure;liquefied-gas as the solvent at high pressure for extracting peanut at 40℃with the extraction rate of 4.91% was better than hexane.教育部留学回国人员科研启动基金资助项目(项目编号);; 福建省新世纪优秀人才支持计划和福建省自然科学基金资助项目(E0710026

Relationship Between SHG EFFect and Crystal Structure in Complexes of Sub-Group Metal Halide and POM

已发现某些金属有机配合物是一类有前景的非线性光学材料，为了系统地探索二次谐波发生（SHg）效应大、综合性能好的新型金属有机配合物非线性光学晶体材料，则有必要探讨它们的性能与结构之间的关系。考虑到某些具有较大二阶极化率的有机分子可能与副族金属卤化物形成配合物，于是对这些配合物的二次谐波效应与晶体结构的关系进行了较系统的研究，发现它们实测的SHg强度的大小与晶体的配位键中离子键和共价键成分的大小相一致。Some organometallic complexes which are a type of potential nonlinear optical materials have been discovered.In order to make a systematic exploration For new organometallic complexes exhibiting large second harmonic generation(SHG)eFFect and good comprehensive properties ,it is necessary to study the relationship between the property and the structure.Considering the possibility of Forming complexes between some organic molecular crystals exhibiting good SHG eFFect and metallic ions of the sub-group,the relationship between the second-harmonic eFFect and the crystal struture of these complexes was investigated systematically.The experimentation discovered that the regularity of their SHG intensity agree with the regularity of the crystal structure.国家自然科学基金、福建省自然科学基

年老化视空间注意脑机制的研究

采用"提示-目标"的视觉实验范式,通过事件相关电位(ERP)技术研究了视觉注意年老化脑机制.青年和老年被试各16名;背景由3个同心黑色圆形线条组成,提示为大、中、小不等的3个圆圈组成,刺激材料是随机选取的大写英文字母,组成3个同心圆圈.不同范围圆圈提示时,靶刺激"T"出现在相对应的圆圈,而两个干扰刺激"T"分别呈现在对侧视野的另外两个圆圈.要求被试人根据提示寻找效应圈的靶字母"T",并尽快尽准确地按键判断出现在左视野还是右视野.结果显示干扰刺激的存在导致靶刺激识别难度增加,引起P1的增强和N1的降低;随着提示等级的增大,两组反应时均逐渐延长,早期ERP成分P1与N1波幅均减小;与青年组相比,老年组反应时更长,后部P1增强、N1抑制,且额区P2成分亦受到显著抑制.研究结果与年老化的"复杂度效应"一致;所发现老年组P2成分的显著抑制,提示年老化可能导致视觉空间注意(非随意注意)的前脑区功能缺陷

Investigation of the origin and evolution of groundwater in Yang-Dai River Plain by chlorine,oxygen 18 and deuterium

通过分析地表水和地下水中氯离子浓度和δd、δ18O值的空间分布特征,揭示了秦皇岛洋戴河平原地下水的形成演化规律.结果发现,洋戴河平原地表河水来源于中上游水库水和大气降水的混合,且河水沿程受到δd、δ18O值、氯离子浓度更低的支流或灌渠水补给,从而使δd、δ18O值、氯离子浓度呈现沿程逐渐降低的现象.山前丘陵区地下水主要接受大气降水的直接补给,洪积扇及山麓地带地下水受到了一定的蒸发作用影响,除了接受丘陵区地下水的侧向补给外,洋河附近地下水还受到洋河水库水的混合.研究区西部咸水带的地下水由上游地下水和大泥河地热咸水混合而成,地热咸水的混合比率约为13%,而东部咸水带的地下水由上游地下水、本地污水和地热咸水混合而成,地热咸水的混合比率不超过9%.在海水入侵区,地下水主要由本区地下淡水和海水(海水混合比率不超过10%)混合而成,并且受到了不同程度的地表水或农田灌溉水的补给,其中,浦河一带是地表水或灌溉水补给较为明显的地段.The aim of this paper is to reveal the origin and evolution of surface water and groundwater by analyzing the spatial distribution of chloride ion concentration and δD and δ18O values in surface water and groundwater in Yang-Dai River Plain.The Yang-Dai River originates from the mixing of water of reservoir and meteoric water,and river water is also from the recharge in the tributary and irrigation ditch which have much lower chloride ion concentration and δD and δ18O values.Therefore,chloride ion concentration and δD and δ18O values in river water decreases gradually from upstream to downstream.The groundwater in hilly area is primarily recharged by meteoric water,and the groundwater in pluvial fan and piedmont experiences evaporation partly.The groundwater in pluvial fan and piedmont is recharged not only laterally by upstream groundwater from mountainous and hilly area,but also by Yang River reservoir water.In the study area,the groundwater in the west part of salty water region is mixed between upstream groundwater and salty geothermal water originated from Danihe area,with a mixing radio of 13% salty geothermal water.In comparison,the groundwater in the east part of salty water region is mixed by upstream groundwater,sewage water and salty geothermal water,with a mixing radio of up to 9% salty geothermal water.In the seawater intrusion region,the groundwater was mainly constituted of local fresh groundwater and intrusive seawater with a mixing ratio of up to 10% seawater,and is also partly recharged by surface water and agricultural irrigation water which have higher contribution to the groundwater recharge in Pu River area.国家重点基础研究发展计划(973)项目(No.2010CB428805); 环保公益性行业科研专项经费项目(No.201309006)~

基于原位自由基共聚技术的复合水凝胶制备及表征

以聚乙二醇与马来酸酐的双酯化产物(MAh-PEG-MAh)、丙烯酰胺(AM)为单体,N,N’-亚甲基双丙烯酰胺(BIS)或对二乙烯基苯(DVB)为交联剂,通过原位自由基共聚法合成了一种复合水凝胶。利用FT-IR、1H-NMR、SEM、TEM表征了凝胶结构和形态;利用XRD研究了凝胶的结晶性;研究了单体用量、分子链段长度、交联剂等因素对凝胶力学性能的影响。研究表明,柔性链段MAh-PEG-MAh以一定尺寸的聚集微区分散于PAM连续相,增强水凝胶的结晶性,且分散相与连续相之间有良好的作用力,当MAh-PEG1K-MAh与AM的物质的量比为1∶8,复合水凝胶的压缩强度达到18.2 MPa左右,力学性能最佳

下调基因PTTG1对人胶质瘤细胞SHG44增殖、凋亡、迁移和侵袭能力的影响

背景与目的:研究表明垂体瘤转化基因1(pituitary tumor-transforming gene 1,PTTG1)在多种癌症中高表达。该研究旨在探讨其对胶质瘤细胞SHG44增殖、凋亡、迁移和侵袭能力的影响。方法:用PTTG1 siRNA干扰胶质瘤细胞SHG44的基因表达,通过实时荧光定量聚合酶链反应(real-time fluorescence quantitative polymerase chain reaction,RTFQ-PCR)和蛋白质印迹法(Western blot)分别在mRNA和蛋白质水平上评估PTTG1沉默效率,进一步检测其对SHG44细胞增殖、凋亡、迁移和侵袭能力的影响。结果:沉默PTTG1基因表达可以显著抑制SHG44细胞增殖(P<0.05)、迁移(P<0.01)和侵袭(P<0.001)能力,增加细胞凋亡(P<0.05)。结论:下调PTTG1的表达可以降低神经胶质瘤的恶化程度,有望成为临床胶质瘤治疗的新靶点。福建省自然科学基金(2016D019);;\n福建省卫计委医学创新项目(2016-CXB-12

“建筑适应性”主题沙龙

"地域建筑"是当下建筑学界共同尊重的准则,但这一术语的过度使用,也使得其内涵在当代建筑创作中逐渐模糊。本期沙龙主题"建筑适应性",是对"地域建造"这一命题的具体化。"适度"的"适应"是当下应当倡导的地域建筑设计创作原则。"建筑适应性"中的"适应",强调对历史文脉与所处环境的积极回应,研究建筑与环境之间的复杂应答关联;除此,"建筑适应性"还强调对经济、技术、材料的"适度

中国旅游发展笔谈——品质旅游

我国经济已由高速增长阶段转向高质量发展阶段。就旅游业而言,也进入了品质化发展的关键阶段。随着人们出游机会的增多,人们对旅游的追求开始从\"有没有\"转向\"好不好\"。国务院发布的《\"十三五\"旅游业发展规划》关于旅游业发展形势的一个重要判断就是\"需求品质化\"。可以说,发展品质旅游既是对高质量发展国家战略的响应,也是满足人民群众美好生活需要的客观要求,同时是旅游业发展进入大众旅游中高级阶段之后的必然选择