National Image of China in the “One Belt and One Road” Related Reports：Based on the Analysis of German newspapers （Süddeutsche Zeitung, Die Welt, Frankfurter Allgemeine Zeitung）

“一带一路”指丝绸之路经济带和21世纪的海上丝绸之路，习近平主席在2013年的9月和10月访问哈萨克斯坦和东盟的时候提出这个概念，是中国的重大战略决策，是我国走向可持续发展的重要途径。“一带一路”倡议获得了多个沿线国家以及组织的积极参与，体现出中国在世界舞台上的积极影响力。 然而，当今国家之间的竞争，已不仅仅是经济、军事等硬实力的较量，特别是对大国而言，与政治、文化相关的软实力的比拼，已经成为新一轮国家竞争的焦点。本文关注作为“一带一路”战略合作点之一的德国，对德国的报纸媒体进行分析，还原德文报纸媒体对“一带一路”的报道所呈现的中国形象。以2013-2015年为时间跨度，以德国三大报纸《南德..."One Belt and One Road" refers to the economic belt of Silk Roads on the Euroasia continent and the Maritime Silk Road in the 21th Century from southeast China to East Africa and Europe through Southeast Asia and Indian Ocean. Proposed by the Chinese president Xi Jinping in October of 2013 during his visit to Kazakhstan and ASEAN. The concept has profound connotation to China’s sustainable develop...学位：新闻与传播硕士院系专业：新闻传播学院_新闻与传播硕士学号：1052013115306

1426—1949年腾格里沙漠边缘区旱涝灾害初探

通过对腾格里沙漠边缘区相关气候灾害的史料和文献进行搜集整理与归纳分析,利用统计分组、时间数列、滑动平均、旱涝等级划分等方法对研究区1426—1949年旱涝灾害的时空变化特征和干湿变化特征进行了研究。结果表明:1426—1949年,腾格里沙漠边缘区共发生旱灾149次(平均每3.52年1次)、涝灾98次(平均每5.35年1次);因各县、区的地貌和建置时间不同,旱涝灾害具有明显的时空差异,在时间尺度上,清朝发生旱涝的频率最高,分别为51%、78.6%,在空间尺度上,沙坡头区发生旱涝灾害次数最多,分别为旱灾110次、涝灾78次;腾格里沙漠边缘区在明朝时期相对干旱,清朝、民国时期湿度增加,这与小冰期全球性的降温、西风强盛导致相对湿度增加和西风带位置南移导致降水增多有关。国家科技基础资源调查专项(2017FY101003);;国家自然科学基金项目(41372180

Expression and Localization of FtsZ from Spirulina platensis in Escherichia coli

fTSz是与真核微管蛋白类似的原核骨架蛋白,能在细胞分裂位点聚合组装成环状结构而调控细胞分裂过程。为了研究钝顶螺旋藻(SPIrulInA PlATEnSIS)fTSz蛋白的功能,构建了钝顶螺旋藻fTSz与绿色荧光蛋白gfP融合表达的质粒,并在大肠杆菌中进行了表达和定位研究,结果发现,表达融合蛋白gfP-fTSz的大肠杆菌细胞由短杆状变为长丝状,且菌丝体长度与融合蛋白的表达量呈正比。在荧光显微镜下观察到融合蛋白gfP-fTSz在长丝状体细菌中呈有规律的点状分布,这说明fTSz蛋白功能高度保守,钝顶螺旋藻fTSz蛋白能识别大肠杆菌分裂位点并装配成环状结构调控大肠杆菌细胞分裂,fTSz蛋白的过量表达能抑制大肠杆菌正常的细胞分裂而导致长丝状体细胞的形成。Prokaryotic cytoskeletal protein FtsZ,a microtubule homolog,assembles into a compact circular structure at the mid-cell and plays an important role in cytokinesis.To explore the function of FtsZ in Spirulina platensis morphogenesis,we cloned the ftsZ gene from S.platensis and constructed its fusion tag of GFP expression plasmid pGFP-FtsZ.The recombined expression vector was transformed to Escherichia coli BL21.Western blot analysis showed that the GFP-FtsZ fusion gene was successfully expressed in the transformant.The transformed bacteria that expressed the GFP-FtsZ protein changed from normal short-rod shapes and formed long filaments.The length of the filamentation cells was proportional to the expression amount of FtsZ in cells.Regular-dot distribution of the GFP-FtsZ fusion protein in transformed bacteria was observed by fluorescent light microscopy.The data demonstrated that FtsZ was a highly conserved functional protein.The FtsZ of S.platensis assembled the complete cytokinesis apparatus and formed a Z-ring structure at the future division site to regulate cell division in E.coli.The overexpression of FtsZ blocked the normal cell cycle and led to cell filamentation.国家自然科学基金资助项目(30571446); 福建省自然科学基金资助项目(2009J01193

Observation on Some Activities of Reproduction in Little Egrets (Egretta garzetta) at Jiyu Island in Xiamen

于 2 0 0 1年 3～ 7月采用颜色标记法 ,记录厦门白鹭保护区内鸡屿岛白鹭 (Egrettagarzetta)卵产出和孵出的顺序和时间 ,并称重卵和雏鸟。有 91 4 %的窝卵数为 4～ 5枚 ,产卵期 7 0± 1 9d ,出壳期 4 2± 1 4d ;卵孵化时间与产卵顺序显著负相关 ;不同产出顺序卵重无差异 ;不同孵出顺序雏鸟早期 (≤ 5d)发育无差异 ,之后差异显著 ,第 4出壳的雏鸟发育水平和成活率较低 ,而第 5出壳的雏鸟最低 ;亲鸟在产卵期的孵化是非连续的 ,而产卵结束后相对连续。如此 ,可以调节孵化时间 ,进而调控异步孵化的程度 ,使雏鸟在生长阶段形成适当的等级差别 ,以获得最大的繁殖收益。Data on breeding of Little egrets (Egretta garzetta) were collected in a period from March to July of 2001 at Jiyu Island in Xiamen Egret Natural Reserve.Eggs and nestlings were marked with colors for identifying the egg-laying and hatchling sequences.Ninety one percent of clutch sizes were 4 and 5,the laying period was 7.0±1.9?d,and hatching spread was 4.2±1.4?d;the incubation time was negatively correlated with the laid order of eggs;the mass was not different for the eggs laid early or late;at early stage of development (≤5?d),nestlings were not different in growth,but a significant difference appeared after then,the rate of growth and survival was the lowest for the 5th hatchling,and the second for the 4th when counting backwards.Incubation was not continuous in laying period,and became relatively continuous after that period.By this way,the parents may regulate the incubation time,and further adjust the asynchronism of incubation,resulting in a dominance hierarchy among the nestlings,which would maximize the reproductive success.福建省自然科学基金资助项目 (D9910 0 0 3 );; 厦门市环境保护科研所资助项

Preparation of polystyrene magnetic microspheres for liquid chips by dispersion polymerization

本文将丙烯酸基磁流体均匀分散到苯乙烯单体中,采用分散聚合法制备出了适于构建液相芯片微球载体的单分散性微米级磁性微球。考察了丙烯酸基磁流体预处理时间、加料顺序和单体量对微球形貌和粒径分布的影响及其条件优化。扫描电镜(SEM)显示磁性微球平均粒径为7.77μM,具有良好的单分散性(多分散指数PdI为1.03),并且表面光滑致密;用超导量子干涉磁强计测量了fE3O4纳米粒子的磁化曲线;用红外光谱(fT-Ir)和热失重(Tg)方法表征了磁性微球的化学结构及fE3O4含量。We present an approach of synthesizing magnetic polystyrene complex microspheres by a facile dispersion polymerization.Monodisperse magnetic polystyrene microspheres,appropriate to construct liquid chip carriers,were prepared via dispersion polymerization by dispersing pre-treated acrylic acid-based magnetic fluid in styrene.The effects of synthetic conditions such as pretreatment time of acrylic acid-based magnetic fluid,feeding sequence and amount of styrene monomer on particles’conformation and their size distribution have been investigated,and parameters were further optimized accordingly.SEM results indicate that the magnetic microspheres have an average diameter of 7.77 μm with excellent monodispersity(PDI 1.03) and smooth and compact surfaces.Magnetization curve of Fe 3 O 4 nanoparticles was obtained using superconducting quantum magnetometer.Chemical structures and content of magnetic Fe 3 O 4 of the microspheres were characterized and analyzed using FT-IR and TGA methods.国家自然科学基金项目(20775065;20835005)资助;教育部高校博士点基金项目(20070384023)资助;国家基础科学人才培养基金项目(J1030415)资

Effects of Moxibustion on Gastric Stress Ulcer Rats' Apoptosis Protein Phosphorylation

目的:研究艾灸对应激性胃溃疡大鼠胃黏膜细胞凋亡蛋白质磷酸化的影响,探讨艾灸促进胃黏膜损伤修复的信号转导机制。方法:将大鼠随机分为正常组、模型组、胃经穴组和对照点组,采用束缚冷应激法制作应激性胃溃疡大鼠模型,肉眼观察大鼠胃黏膜损伤程度,APOPTOSIS MICrOArrAy SlIdES芯片检测胃黏膜细胞凋亡蛋白质磷酸化水平。结果:与模型组比较,胃经穴组和对照点组大鼠胃黏膜损伤指数值均显著降低(P<0.05);与对照点组比较,胃经穴组大鼠胃黏膜损伤指数显著降低(P<0.05);APOPTOSIS MICrOArrAy SlIdES芯片检测结果显示:与模型组比较,胃经穴组大鼠胃黏膜细胞10种蛋白质磷酸化水平上调,其中bCl-Xl、MCl-1、bCl-2、IAPS 4种蛋白磷酸化水平差异有统计学意义(P<0.01,P<0.05);18种蛋白质磷酸化水平下调,其中Tnf、fAS、APAf-1、CASPASE-3、CASPASE-9、bAX 6种蛋白质磷酸化水平差异有统计学意义(P<0.01,P<0.05)。结论:艾灸可促进胃黏膜的损伤修复,调节多种凋亡相关信号蛋白质的磷酸化水平,并且存在一定的经脉脏腑相关性。Objective: To study the effects of moxibustion on apoptosis protein phosphorylation in rats with gastric stress ulcer and to explore the signal transduction mechanisms promoting gastric mucosal injury and repairing moxibustion.Methods: The rats were randomly divided into normal group,model group,stomach meridian group and the control point groups and each group had 10 rats.The stress ulcer rat model was established by using restraint cold stress method.We observed the rat gastric mucosa injury degree and Apoptosis Microarray Slides microarray was used to observe the gastric apoptosis protein phosphorylation levels.Results: Compared with the model group,the gastric mucosa injury index values of control point and meridian groups were significantly lower( P < 0.05).Compared with the control point group,a significant reduction in rat gastric mucosa injury index was in meridian group( P < 0.05).Apoptosis Microarray Slides microarray results showed that 10 kinds of protein phosphorylation levels increased,among which Bcl- XL,Mcl- 1,Bcl-2 and IAPs protein phosphorylation levels were statistically significant( P < 0.01,P < 0.05) and 18 kinds of protein phosphorylation levels decreased,among which TNF,Fas,Apaf- 1,Caspase- 3,Caspase- 9 and Bax protein phosphorylation levels were statistically significant( P < 0.01,P < 0.05).Conclusion: Moxibustion can promote gastric mucosal injury and repair and regulate phosphorylation of several proteins related to apoptotic signals and there is a certain correlation between the meridians organs.国家自然科学基金项目(30960484;81260556

术前口服倍他乐克对于麻醉诱导丙泊酚的用量和血流动力学的影响

【目的】本研究探讨术前口服倍他乐克对麻醉诱导时丙泊酚的用量和血流动力学变化的影响。【方法】选择择期手术的全麻病人（ASAⅠ～Ⅱ）60例，随机分成两组，每组30例，第一组为实验组（B组），术前口服倍他乐克50mg，第二组为对照组（C组）给予安慰剂；以30mg·kg^-1·h^-1的恒速灌注丙泊酚至BIS达到50，记录病人入睡时和BIS=50时丙泊酚的用量以及插管前后血压、心率、中心静脉压和心输出量变化。【结果】两组病人入睡时丙泊酚的用量：B组是（1_35±0．22）mg·kg^-1；C组是（1．60±0．24）mg·kg^-1，组间差异P〈0．01；BIS=50时的丙泊酚的用量：B组是（1．71±0．27）mg·kg^-1；C组是（1．98±0．24）mg·kg^-1；组间差异P〈0．01；B组插管前、后血压和心率的变化程度较C组小（P〈0．05），插管过程中心静脉压和心输出量组间变化差异不大。【结论】术前口服倍他乐克50mg减少麻醉诱导丙泊酚的用量，插管时的血流动力学相对稳定

养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌临床研究

目的观察养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌(NSCLC)的临床疗效。方法采用随机数字表法将89例晚期NSCLC患者分为对照组44例及观察组45例。2组均采用GP方案;观察组并予养正消积胶囊,每次4粒,每日3次,口服。2组均21d为1个周期,连续治疗2个周期,随访1年。观察2组治疗前后Ki67、Bax、Bcl-2蛋白表达及肿瘤标志物[血管内皮生长因子(VEGF)、骨桥蛋白(OPN)、癌胚抗原(CEA)、糖类抗原199(CA199)]、中医症状评分、生活质量评分,比较2组客观缓解率(ORR)、疾病控制率(DCR)、无进展生存时间(PFS),监测不良反应。结果观察组ORR、DCR明显优于对照组(P<0.05)。与本组治疗前比较,观察组治疗后、随访1年VEGF、OPN、CEA、CA199水平明显降低(P<0.05);对照组治疗后上述指标明显降低(P<0.05),随访1年CEA水平明显降低(P<0.05)。与本组治疗前比较,2组治疗后Ki67、Bcl-2蛋白表达明显降低,Bax蛋白表达明显升高(P<0.05);2组治疗后比较,观察组Ki67、Bcl-2蛋白表达低于对照组(P<0.05),Bax蛋白表达高于对照组(P<0.05)。与本组治疗前比较,2组治疗后中医症状评分(神疲乏力、胃纳少馨、腰膝无力、夜尿频多、头晕目眩)、生活质量评分(躯体功能、认知功能、社会功能、情绪功能)明显改善(P<0.05);2组治疗后比较,观察组上述评分改善明显优于对照组(P<0.05)。观察组PFS明显长于对照组(P<0.05),不良反应明显低于对照组(P<0.05)。结论养正消积胶囊辅助GP方案治疗晚期NSCLC可有效降低患者肿瘤标志物水平,改善生存质量,减少吉西他滨和顺铂的不良反应,提高疗效。福建省卫生厅中医药科研专项课题(wst201210