138 research outputs found

    An Exploration of Theory of Harmonious Urban Management

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    随着社会经济的发展,城市管理行政执法事业渐渐成为我国城市建设管理一个重要组成部分,也是展示城市建设管理水平的一个重要标志。特别是在“和谐社会”理念提出以后,城市管理的工作成为了“和谐政府”的一个形象窗口。为此,加强对城市管理行政执法事业的建设,对建设“和谐社会”有重要的意义。本文将在讨论城市管理事业与社会经济发展关系的同时,初步提出“和谐城管”的理论,并探讨该理论的提出对城市管理事业的作用和对社会经济发展的作用。 随着我国城市化进程的加快,城市管理中所积累的社会矛盾和社会问题越来越突出。城市的洁净、规范、文明和有序运转,是改革、发展和稳定的需要,也在根本上维护着城市居民的合法利益。但我国目前...Along with the social and economic development, administration enforcement of urban management has gradually become an important part of urban construction in China, even an important symbol of demonstration of the urban construction and management level. Especially, with the concept of a harmonious society, the urban management work has become an image of harmonious government. Therefore, strengt...学位:经济学硕士院系专业:经济学院经济系_政治经济学学号:1532006115076

    我国企业加速器的实践与思考

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    近年来.我国已经开始注意到瞪羚企业对经济的巨大贡献,开始有意识地制定一些针对瞪羚企业的扶持与培植措施。目前,这些培植与扶持措施主要有两方面:一是为瞪羚企业疏通资金渠道,帮助瞪羚企业获得发展所需资源:二是成立"企业加速器",为瞪羚企业提供综合性服务。前者的代表是北京中关村科技园区实施的"瞪羚计划"。它将信用评价,信用激励和约束机制同担保贷款业务有机结合,通过政府的引导和推动,凝聚金融资源,构建高效

    孵化器应该由谁来孵化

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    忽视对孵化器本身生长规律的探究和总结,就如同仅以小孩的健康成长为中心,却无视母亲健康的做法一样。孵化器的迅猛发展,有力地推动了科技型企业的发展,为企业技术创新开辟了广阔的空间。但是,现阶段我国孵化器的发展主要是由政府自上而下推动的,它们的成立缺乏深厚的市场基础,一些初创的孵化器尤其是地处欠发达地区的初创孵化器运转状况不尽人意。此前,谈起孵化器的作用,人们总是强调其哺育初创企业的作用,往往忽视其本身也有创造价值、解决就业的作用;在研究孵

    企业孵化器的复杂性:分析与启示

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    企业孵化器作为国家创新体系的重要组成部分,其本身蕴含了内在的复杂性机理。阐述了从线性思维到复杂分析的企业孵化器认知过程,分析了企业孵化器的复杂性特征以及成因,并得出了几点关于孵化器管理的启示。其要点为:企业孵化器不仅要为在孵企业提供各种外部支持,更要建立以知识交流与共享为核心的促进在孵企业内生活力的微观机制,以提高自身成长的能力。国家软科学研究计划(2004DGQ1D110

    基于在孵企业观点的孵化服务重要性评估研究

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    将孵化服务分为八大类共66个具体项目,通过问卷调查收集在孵企业对各项孵化服务的需求信息,采用R id it方法进行排序。发现:在孵企业对孵化器提供的各项服务的需求是有差别的,被认为最重要的服务是孵化器提供的政策法律支持和财务及融资服务;在各具体服务项目中,在孵企业钟情于容易评估的服务项目,对那些可以自行解决的简单服务和不容易在短时期内见成效的服务项目普遍不感兴趣;不同行业的在孵企业对孵化服务的需求既有共同点也存在较多差异;以成立时间为基准分成的三组在孵企业在孵化需求方面并不存在大的差别。国家软科学研究计划(2004DGQ1D110

    Impacts of surface micro-topography on cellular biological responses

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    与常规的细胞体外培养器皿不同,细胞在体内生长时,其微环境并不是简单的平面形式,每一种组织都有其特定的三维微结构。这类具有微结构的微环境是细胞生长、分化的重要调控因子。近年关于基底微拓扑结构影响细胞生长、分化等行为研究的文献迅速增加,研究发现,具有微拓扑结构的基底可改变细胞的铺展、迁移、取向等行为,引导细胞骨架的重排,调控干细胞分化潜能,对于体外组织构建以及医学植入材料的表面处理具有指导性意义。本文就有关基底微拓扑结构影响细胞生物学研究的最新进展进行了综述

    Analysis of the nutrient distribution features and affecting factors in the Jiulongjiang estuary

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    根据2009、2010年“丰水期“和“枯水期“四航次九龙江河口混合区的调查资料,且结合历史资料对营养盐含量及分布特征、周日变化特征进行了统计和相关分析,研究了九龙江流域营养盐输入海洋的变化过程,探讨九龙江河口营养盐伴随潮汐变化,以及河口混合过程中的生物地球化学行为。调查期间溶解无机氮、硅和磷含量的平面分布呈现出由径流冲淡水高值向河口外海端递减的变化趋势;在涨潮时,河口区感潮段高溶解无机氮、硅、磷营养盐的陆源冲淡水与低溶解无机氮、硅、磷营养盐外海水相遇,随着外海水的侵入,外海水的作用逐渐加强,在稀释混合过程中呈现出无机营养盐逐步降低的变化趋势,退潮时则相反;营养盐在这复杂的河口过程中往往表现出在水动力的作用下稀释混合是主要过程,无机氮和活性硅酸盐在河口稀释混合过程中呈现保守性特征,活性磷酸盐在河口转移(补充)过程的行为复杂化,呈现缓冲作用为主。Based on the historical data and the data from four surveys in the wet season and dry season of 2009 and 2010 in the Jiulongjiang estuary,the concentration and distribution of nutrient were discussed in the mixing process.Furthermore,the daily variation of nutrient concentration with the tide was also discussed.The results showed that:(1) the concentration of total dissolved inorganic nitrogen,silicate and phosphate all decreased gradually from the river runoff to seawater;(2) in high tide,in the mixing process of the runoff with high nutrient concentration and the seawater with low concentration of nutrient,the concentration of nutrient decreased due to seawater.On the contrary,during the ebb,the concentration of nutrient increased due to the runoff;(3) in the mixing process in Jiulongjiang estuary,nitrogen and silicate were both conservatively diluted,but phosphate was buffered because of the complicated transfer and complement of phosphate.国家海洋局公益性项目(200805064);国家海洋局第三海洋研究所基本科研业务费项目(海三科2009021);海三科200900

    基底力学微环境对干细胞生物学功能的影响

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    目的:干细胞是一类没有分化的多潜能细胞,具有无限自我增殖和分化成多种细胞的能力。干细胞生长的生理微环境称为壁龛(niche),基底硬度、拓扑结构和三维尺寸等物理力学特征决定干细胞的命运。尽管越来越多的证据证明基底力学微环境对干细胞干性及分化具有重要影响,但基底硬度、拓扑结构和三维尺寸单因素及多因素耦合如何影响干细胞的特性及其分子机制还不够清楚。方法:为模拟体内干细胞生长力学微环境,考察不同基

    Differential regulation of stiffness, topography, and dimension of substrates in rat mesenchymal stem cells

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    The physiological microenvironment of the stem cell niche, including the three factors of stiffness, topography, and dimension, is crucial to stem cell proliferation and differentiation. Although a growing body of evidence is present to elucidate the importance of these factors individually, the interaction of the biophysical parameters of the factors remains insufficiently characterized, particularly for stem cells. To address this issue fully, we applied a micro-fabricated polyacrylamide hydrogel substrate with two elasticities, two topographies, and three dimensions to systematically test proliferation, morphology and spreading, differentiation, and cytoskeletal re-organization of rat bone marrow mesenchymal stem cells (rBMSCs) on twelve cases. An isolated but not combinatory impact of the factors was found regarding the specific functions. Substrate stiffness or dimension is predominant in regulating cell proliferation by fostering cell growth on stiff, unevenly dimensioned substrate. Topography is a key factor for manipulating cell morphology and spreading via the formation of a large spherical shape in a pillar substrate but not in a grooved substrate. Although stiffness leads to osteogenic or neuronal differentiation of rBMSCs on a stiff or soft substrate, respectively, topography or dimension also plays a lesser role in directing cell differentiation. Neither an isolated effect nor a combinatory effect was found for actin or tubulin expression, whereas a seemingly combinatory effect of topography and dimension was found in manipulating vimentin expression. These results further the understandings of stem cell proliferation, morphology, and differentiation in a physiologically mimicking microenvironment
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