Studies on the Synthesis and Photovoltaic Properties of C60-based Acceptors

太阳能作为最有可能取代化石能源的可再生能源，其开发和利用成为人们关注的焦点，于是有机聚合物太阳能电池的研究应运而生。其制备过程简单、成本低、质量轻、可制备成柔性器件，有广阔的应用前景。近年来聚合物太阳能电池取得了良好的进展，给体材料方面的进展尤其明显。但光伏特性优异的电子受体材料依然不多，目前使用最普遍的电子受体材料仍然是[6，6]-苯基-C61-丁酸甲酯(PCBM)和[6，6]-苯基-C71-丁酸甲酯(PC70BM)。合成具有高的LUMO轨道、光吸收范围宽并且在可见光区（400-800nm）有强吸收的新型富勒烯受体材料，对于有机太阳能电池的进一步发展至关重要。 我们合成了一系列具有较高的L...As one of the most potential and renewable alternatives to fossile energy,solar energy has been explored widely to facilitate the development of polymer solar cells. Polymer solar cells hold promising prospect with advantages of easy fabrication, low cost, lightness and flexibility.Recently, great progresses have been made on polymer solar cells, especially on the development of donor materials. H...学位：理学硕士院系专业：化学化工学院化学系_无机化学学号：2052010115155

Shrew in novels during late Ming Dynasty and early period of Qing Dynasty

内容摘要明末清初作为一个特别的时期存在于中国历史之中。虽然跨越两个不同的朝代，但是妒妻悍妇作为一个“风潮”，从明代的中后期一直延续到了清代，甚至在明末清初这个时期成为小说、戏曲的表现主题，可谓这个时期的时代特征之一。本文结合此时期的种种社会状况来探讨妒妻悍妇的生成原因、意义以及这个群体和整个社会的互动和影响。虽然在古籍中的“泼妇”、“悍妇”等字眼充斥其中，但是其意义还是有很多不同的。有时，这些词语代表的是反抗官府、自行其是的“刁民”。在本文中，“妒妻悍妇”已经回归到了它的本来意义——主要指家庭婚姻关系中妻子和丈夫以及他人之间的对立。本文认为明代以理学治国，大力提倡节烈意识，但是在其后期有不少妒...The Late Ming Dynasty and the early period of Qing Dynasty is very special time in Chinese history. During the period, shrew being as fashion is wildly existed. And it became so much as the popular topic in novels and arts. This article is focused on the shrew, including reason, outcome and influence which based on all kinds of social society's situation. There were lots of shrews in the history ...学位：历史学硕士院系专业：人文学院历史学系_中国古代史学号：20040201

A Study on Taxation Policies For Employment Promotion

就业是民生之本，关系到千家万户的生活。就业问题如不能有效解决，将会成为影响我国经济发展和社会稳定的障碍。在结构升级、社会转型的历史时期，我国政府面临巨大的就业压力，而全球国际金融危机的爆发，使我国的就业形势更为严峻。如何扩大就业，缓解就业压力，是我国当前和未来必须面对的重要社会经济课题。税收作为宏观调控的重要手段，能够在不同层次上影响就业水平和就业结构。现行的税收政策在支持就业方面存在一定的积极性，但是仍然存在一些问题和不足，如何完善我国促进就业的税收政策，使其在解决就业问题上发挥更大的作用，具有十分重要的研究意义。 首先，本文以经济学、税收学等理论为基础，从劳动力需求和供给两方面分析了税收...Employment is the thing related to the lives of millions of households. If the employment problem can not be effectively solved, it will be affecting China's economic development and social stability. During the period of economic structure update and social transition, China's government has been facing huge employment pressure. And the onset of global financial crisis has made the situation more...学位：经济学硕士院系专业：经济学院财政系_财政学(含税收学)学号：1552007115004

Study on the gene expression profile in the bone tissue in primary osteoporosis with kidney-yang deficiency syndrome

目的通过检测原发性骨质疏松症不同中医证型患者骨组织基因表达谱的差异,探讨原发性骨质疏松症肾阳虚证相关基因的信息学特征。方法随机选择原发性骨质疏松; 症患者,中医辨证分型为肾阳虚证组3例,肾阴虚证组3例,无肾虚证组3例,并选择正常骨密度人群3例设为正常对照组。用人全基因组表达谱芯片检测4组人群; 骨组织基因表达谱,筛选共同的差异表达基因,并对这些差异表达基因进行基因通路等相关功能分析。结果肾阳虚证组与正常对照组、肾阴虚证组、无肾虚证组的差; 异表达基因分别为2631条、3976条、6184条;肾阳虚证组与其他3组比较共同的差异表达基因有1037条。这些差异基因参与补体与凝血级联反应、; Hedgehog、TGF-beta、细胞周期等22条信号通路。结论原发性骨质疏松症肾阳虚证的相关基因主要与免疫调节、TGF-beta、细胞周期等; 信号通路相关。Objective To investigate the characteristics of genes expression; profiles of primary osteoporosis with kidney yang deficiency through; analyzing the gene expression difference with gene micro-array. Methods; Patient with osteoporosis were rand omly divided into kidney-yang; deficiency group (n = 3),kidney-yin deficiency group (n = 3),non-kidney; deficiency group (n = 3),according to the syndrome differentiation of; traditional Chinese medicine. Another 3 people with normal BMD were; selected as normal control. Expression profiles of the bone tissue from; 4 groups were detected to screen differentiated expression genes.; Analysis of pathway and other function among these genes was conducted.; Results The number of differentiated expression genes in kidney-yang; deficiency group were 3976,6184,and 2631,compared to kidney-yin; deficiency,non-kidney deficiency,and normal control group,respectively.; The number of common differentially expressed genes were 1037. These; genes were involved in 22 pathways,including complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle. Conclusion Genes related to kidney-yang deficiency syndrome in; primary osteoporosis are mainly related to complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle.福建省科技厅省属公益类科研院所基本科研专项; 福建省自然科学基金项

Uncertainty Analysis of Satellite Panel System

为了研究不确定性参数对卫星帆板系统展开锁定动力学响应过程的影响,对参数为随机和认知不确定性两种情况进行了分析。首先在AdAMS中建立了卫星帆板系统多体动力学模型并建立模型语言文件AdM、脚本控制文件ACf,在MATlAb环境下编辑脚本仿真分析程序进行不确定性多体动力学仿真分析。当参数为随机不确定性时,采用蒙特卡罗方法进行参数抽样并求得响应的置信区域;参数为认知不确定性时,用区间分析的方法求得系统响应边界。联合仿真结果表明两种不确定性分析方法均能定性分析参数不确定性对卫星帆板系统展开锁定响应过程的影响,为卫星帆板系统结构设计提供一定的参考依据。In order to study the impact of uncertainty parameters on the satellite panel system's launched and locked dynamic response,random uncertainty and epistemic uncertainty of parameters is studied.First the muti-body dynamic model of satellite panel system is established in ADAMS.The model language file ADM and script control file ACF are also established.Uncertainty muti-body dynamics is analyzed using MATLAB script program.When the parameters are random uncertainty, using monte-carlo sampling methods for parameters obtains the confidence region of response.When the parameters are epistemic uncertainty,interval analysis method is used to study the boundary of system response.Co-simulation results show that two kinds of uncertainty analysis method can qualitatively analyze the impact of parameters uncertainty on the satellite panel system response.That provides some reference basis to design satellite panel system structure.国家“863”计划(2008AA12A205); 南京航空航天大学基本科研业务费专项科研项目(NJ2010009;NS2012015

基于电子鼻的慢性胃炎气滞证患者常见病位的口腔呼气气味图谱研究

目的:运用电子鼻探讨慢性胃炎气滞证患者常见病位的口腔呼气气味图谱特征。方法:采用证素辨证的方法,筛选出397例慢性胃炎气滞证患者并判断病位证素,同时运用基于阵列式气体传感器技术的医用电子鼻(EN0l1103-A)采集其口腔呼气的气味图谱,选择气味图谱响应曲线的振幅、斜率作为图谱特征参数,借助分类器算法对慢性胃炎气滞证与非气滞证的口腔呼气气味图谱特征进行模式识别,比较慢性胃炎气滞证患者常见病位的口腔呼气气味图谱特征。结果:慢性胃炎气滞证的主要病位证素分布是胃(91.18%)、脾(38.29%)、肝(23.68%);主要病位为胃、脾胃、肝脾胃、肝胃;采用分类器算法对慢性胃炎气滞证的气味图谱进行模式识别时,运用随机森林算法,对气滞证的准确率可以达到65.85%;病位胃组、脾胃组的气味图谱响应曲线B、C、D、E、F、I、J的振幅均显著低于病位肝脾胃组(P<0.01);病位胃组、脾胃组的气味图谱响应曲线C、D、E、F、I的斜率均显著低于病位肝脾胃组(P<0.01),脾胃组曲线A的斜率低于病位肝脾胃组(P<0.05)。结论:运用电子鼻结合模式识别方法可初步判断慢性胃炎气滞证及其不同病位间的口腔呼气气味差异。国家自然科学基金项目(No.81373552);;福建省自然科学基金项目(No.2014J01362);;福建省中医药科研项目(No.wzpw201313);;福建省教育厅A类项目(No.JA14212);;载人航天领域预先研究项目(No.020104)~

Electrocatalytic Oxidation of Ethanol on Pt/nanoTiO_2-CNT Complex Catalysts

通过前驱体Ti(OEt)4直接水解和电化学扫描电沉积法制备在Ti基体上的纳米TiO2-碳纳米管复合膜载Pt(Pt/nanoTiO2-CNT)复合催化剂.透射电镜(TEM)和X射线衍射(XRD)结果表明,锐钛矿型纳米TiO2粒子和Pt纳米粒子(粒径均为5～10nm)均匀地分散在碳纳米管表面.通过循环伏安和计时电流法研究表明,Pt/nanoTiO2-CNT复合催化剂(Pt载量为0.32mg·cm-2)具有高达51.8m2·g-1的电化学活性比表面积,常温常压下对乙醇的电化学氧化具有高催化活性和稳定性,乙醇氧化峰电位分别为0.59、0.96和0.24V,氧化峰电流密度分别达到-115、-113和-75mA·cm-2.复合催化剂对乙醇电氧化的高催化活性可归因于nanoTiO2、CNT和Pt纳米粒子的协同催化作用.Pt/nanoTiO2-CNT complex catalysts were prepared by direct hydrolysis of Ti(OEt)4 and electrochemical scan electrodepositing method. The results of XRD and SEM showed that the nanoTiO2 (anatase) and Pt nanoparticles (size about 5～10 nm) were dispersed uniformly on CNT film surface. The electrocatalytic activity of Pt/nanoTiO2-CNT electrode was investigated by cyclic voltammetry and chronopotentiogram. The results indicated that Pt/nanoTiO2-CNT electrode (Pt loading was 0.32 mg·cm-2) exhibited high electrochemical activity surface area (51.8 m2·g-1) and very high electrocatalytic activity and stability for the electro-oxidation of ethanol at room temperature in atmosphere pressure. The oxidation peak potentials of ethanol were 0.59, 0.96, and 0.24 V, and the corresponding oxidation peak current sdensities were -115, -113, and -75 mA·cm-2. The high electrocatalytic activity and good stability can be attributed to the synergistic catalytic effect among nanocomposite.国家自然科学基金(20476001);; 安徽省自然科学基金(00045317)资助项

可储存介孔氧化锆-磷酸钙根管充填糊剂的实验研究

目的制备可储存介孔氧化锆-磷酸钙根管充填糊剂(简称糊剂),并对其显影效果、理化性能、可储存性能及生物相容性进行评价。方法制备具有有序六方孔结构的钛稳定介孔氧化锆,并将其(质量分数5%、10%、15%、20%)与自固化磷酸钙骨水泥粉末混合制得介孔氧化锆-磷酸钙根管充填糊剂。通过X射线拍摄评价糊剂的显影效果;通过测试收缩率、薄膜厚度、流动性和溶解性评价糊剂的理化性能;通过测试不同储存时间糊剂的流动性能评价其可储存性;通过细胞毒性实验、口腔致敏动物实验、皮下组织埋植动物实验对糊剂进行生物安全性评价。结果①含有质量分数15%介孔氧化锆-磷酸钙根管充填糊剂显影效果满足临床需要;②所制糊剂的各项理化性能均符合ISO 6876中关于根管充填糊剂理化性能的评价标准;③所制糊剂可在4℃、50%相对湿度环境下长期密封保存;④所制糊剂材料对L-929细胞无毒性,无口腔黏膜刺激反应,不会对皮下组织产生毒害作用。结论可储存介孔氧化锆-磷酸钙根管充填糊剂具有良好的显影性能、理化性能、可储存性能及生物安全性,对根管充填的临床应用具有积极意义

Development of Electrochemical Biosensor for Detection of PML/RARα Fusion Gene in Acute Promyelocytic Leukemia

针对急性早幼粒细胞白血病(APl)中PMl/rArα融合基因的碱基序列,设计了锁核酸(lnA)修饰的发夹结构捕获探针,结合信号探针构建新型的“三明治“电化学传感模式。信号探针末端修饰的生物素可与酶上的亲和素结合,通过检测酶催化H2O2氧化底物3,3',5,5'-四甲基联苯胺(TMb)产生的电化学信号,实现对靶序列的检测。该传感器可识别和定量检测PbS缓冲液中人工合成的PMl/rArα融合基因序列。结果表明,该传感器能很好地区分互补序列、单碱基及多碱基错配序列,杂交电流值与目标链浓度在1.0x10-11~1.6x10-10 MOl/l范围内呈较好的线性关系,检出限为1.0x10-13 MOl/l。同时,该新型传感器成功地用于无稀释人血清中PMl/rArα融合基因的检测,具有特异性强、灵敏度高和重复性好的优点,有望用于临床实际样品的检测,进而实现临床上急性早幼粒细胞白血病的早期诊断及预后判断。A novel DNA electrochemical probe(locked nucleic acid,LNA) was designed and involved in constructing an electrochemical DNA biosensor for the detection of PML/RARα fusion gene in acute promyelocytic leukemia(APL).This biosensor was based on a "sandwich" detection strategy,which involved a pair of LNA probes,e.g.hairpin capture probe and reporter probe.Streptavidin-HRP was bound to biotin labeled at the end of reporter probe via streptavidin-biotin affinity binding.In the presence of hydrogen peroxide(H2O2),HRP catalyzed the oxidation of the substrate 3,3′,5,5′-tetramethylbenzidene(TMB) to offer an enzymatically amplified electrochemical current signal for the detection of target DNA.This sensor was applied in the direct quantitative detection of synthetic PML/RARα fusion gene in PBS buffer.The results indicated that the biosensor showed an excellent specificity to distinguish the complementary sequence and different mismatch sequences.A linear relationship between the amperometric signal and the target concentration was obtained in the range of 1.0×10-11-1.6×10-10 mol/L with a detection limit of 1.0×10-13 mol/L.In addition,the biosensor was used for the determination of PML/RARα fusion gene in human serum samples without dilution with high sensitivity,selectivity and good repeatability.This method would be expected to use in real sample for further solving the actural problems of early diagnosis and prognosis monitoring of APL.863计划资助项目(2008AA02Z433);福建省高校产学研科技重点项目(2010Y4003);国家自然科学基金资助项目(20805006;20975021);福建省自然科学基金资助项目(2010J05019

术前口服倍他乐克对于麻醉诱导丙泊酚的用量和血流动力学的影响

【目的】本研究探讨术前口服倍他乐克对麻醉诱导时丙泊酚的用量和血流动力学变化的影响。【方法】选择择期手术的全麻病人（ASAⅠ～Ⅱ）60例，随机分成两组，每组30例，第一组为实验组（B组），术前口服倍他乐克50mg，第二组为对照组（C组）给予安慰剂；以30mg·kg^-1·h^-1的恒速灌注丙泊酚至BIS达到50，记录病人入睡时和BIS=50时丙泊酚的用量以及插管前后血压、心率、中心静脉压和心输出量变化。【结果】两组病人入睡时丙泊酚的用量：B组是（1_35±0．22）mg·kg^-1；C组是（1．60±0．24）mg·kg^-1，组间差异P〈0．01；BIS=50时的丙泊酚的用量：B组是（1．71±0．27）mg·kg^-1；C组是（1．98±0．24）mg·kg^-1；组间差异P〈0．01；B组插管前、后血压和心率的变化程度较C组小（P〈0．05），插管过程中心静脉压和心输出量组间变化差异不大。【结论】术前口服倍他乐克50mg减少麻醉诱导丙泊酚的用量，插管时的血流动力学相对稳定