论我国银行不良信贷资产及其处置:不良信贷资产证券化的途径和策略

国际金融史上银行经营失败的教训揭示了一个不容忽视的问题—银行不良贷款问题。长期以来,这一问题一直困扰国际银行业,成为导致银行经营失败的主要原因。目前,我国银行体系中不良贷款问题日益严峻,严重影响了国有企业和国有银行的商业化改革。深入剖析我国不良贷款问题的特殊性,分析其现实根源,探索解决银行不良贷款问题的思路,已成为当务之急。通过对国际上银行不良信贷资产重组的比较分析,可以从政府在重组中发挥作用的程度、不良信贷资产及其损失的承担主体、分散或集中处理的选择、政府或银行主导解决策略的选择等方面归纳为银行主导重组或自主重组的波兰模式、政府强制重组并独担损失的匈牙利模式、政府强制或政府督导下的多方共担损...学位：经济学硕士院系专业：经济学院财政金融系_金融学(含保险学)学号：K19993101

X连锁淋巴细胞异常增生症死亡1例

XLP存在复杂多样的临床表现,其中以爆发性传染性单核细胞增多症型临床经过尤为凶险,诊疗过程中多无法及时诊断,且对症治疗方案多无明显效果,患者可迅; 速死亡,极易引起医疗损害而需要法医学鉴定。笔者认为遇到怀疑XLP进行鉴定时需把握下列几个要点:(1)该病发病机理为病毒感染引起淋巴细胞过度增殖,; 浸润多个器官,需做CD20、CD3、TdT、MPO等抗体的免疫组织化学染色,以鉴定增殖淋巴细胞的类型,排除其他血液系统疾病;(2)该疾病属性连锁; 隐性遗传性疾病,应尽量询问、调査被鉴定人相关亲属的资料,以确定其是否与遗传相关,须与散发性传染性单核细胞增多症鉴别;(3)由于基层法医鉴定机构多; 不具备相关分子生物学检査手段,无法从基因突变上作出明确诊断,还需依据尸体检验结果并结合具体临床表现综合考虑

11例脂肪栓塞法医学鉴定分析

目的探讨脂肪栓塞法医学鉴定的思路及注意要点。方法回顾性分析某司法鉴定中心2007年1—12月共计11例脂肪栓塞死亡的案例,观察HE切片及苏丹IV染色切片。结果 11例肺组织内均见大量脂滴,2例脑和其他脏器小血管内见脂滴,肝脂肪变性6例。结论结合案例分析脂肪栓塞栓子来源,临床表现和死亡机制,总结出脂肪栓塞案件鉴定的一些经验和工作思路

The Influence of Magnesium Supplementation on Glucose and Lipid Metabolism of Rats with Type 2 Diabetes Mellitus

目的:研究镁补充对2型糖尿病大鼠糖脂代谢的影响。方法:将用高脂饮食联合链脲佐菌素(STz)方法诱发的2型糖尿病大鼠随机分为四个组,糖尿病对照组喂饲高脂饲料,高、中、低剂量组在高脂饲料中分别加入2000、1000、200 Mg/kg的镁(以镁离子计)。自由饮食喂养四周,处死动物。用放射免疫法测血清胰岛素(InS)水平、用葡萄糖氧化酶法测空腹血浆葡萄糖(fASTIng PlASMAgluCOSE,fPg),并计算胰岛素敏感指数(InSulIn SEnSITIVITy IndEX,ISI)。比色法检测糖化血红蛋白(glyCOSylATEd HEMOglObIn,HbA1C)。用全自动生化分析仪测高密度脂蛋白胆固醇(HIgH-dEnSITy lIPOPrOTEIn CHOlESTErOl,HdlC)、甘油三酯(TrIglyCErIdE,Tg)、总胆固醇(TOTAl CHOlESTErOl,TC)。结果:高剂量组的空腹血糖、空腹血清、糖化血红蛋白、甘油三酯、总胆固醇水平均较糖尿病对照组显著性降低(P<0.05),而高密度脂蛋白胆固醇、胰岛素敏感指数较糖尿病对照组显著性升高(P<0.05)。结论:镁补充可以提高2型糖尿病大鼠胰岛素敏感性,改善糖尿病大鼠的糖脂代谢情况。Objective: To investigate the effect of magnesium supplementation on glucose and lipid metabolism of rats with type 2 diabetes mellitus.Method: Rats with type 2 diabetes mellitus were induced with high fat diet and intraperitoneal injection with small dose of STZ,then they were divided into 4 groups randomly: high,medium,low magnesium supplementation groups and diabetes mellitus control group.Diabetes mellitus control group was feed with high-fat feed only.The dosage added in high-fat feed of the high,medium,low magnesium supplementation groups are 2000,1000,200 mg/kg(measured by Mg2+).All the rats ate and drunk freely.All rats were killed after four weeks.The serum insulin(Ins) level were tested with radiation immune method,fasting plasma glucose(FPG)were mea-sured with glucose oxidase method,and calculation the insulin sensitivity index(ISI).Glycosylated hemoglobin(HbA1c) was measured by chromatometry.High-density lipoprotein cholesterol(HDLC),triglyceride(TG),total cholesterol(TC) were measured by automatic biochemical analyzer.Results: FPG,Ins,TG,TC levels of high dose group was significantly lower compared with that in the diabetic control group(P<0.05),while HDLC,ISI increased significantly compared with that in the diabetic control group(P<0.05).Conclusion: Magnesium supplement can improve insulin sensitivity,improve glucose and lipid metabolism in type 2 diabetic rats

INFLUENCE of MAGNESIUM SUPPLEMENTATION ON INSULIN RESISTANCE AND THE INFINITY of RECEPTOR IN RATS WITH TYPE 2 DIABETES MELLITUS

目的观察镁补充对2型糖尿病大鼠胰岛素受体亲和力的影响。方法将用高脂饮食联合链脲佐菌素(STz)方法诱发的2型糖尿病大鼠随机分为4个组,糖尿病对照组喂饲高脂饲料,高、中、低剂量组在高脂饲料中分别加入2000、1000、200Mg/kg的镁(以镁离子计)。每周检测空腹血糖1次。自由饮食喂养4 W,处死动物。用放射性受体分析法测肝细胞胰岛素受体亲和力、放射免疫法测血清胰岛素(InS)水平、比色法检测糖化血红蛋白(HbA1C)和血浆丙二醛(MdA)、葡萄糖氧化酶法测空腹血浆葡萄糖(fPg),并计算胰岛素敏感指数(ISI)和抵抗指数(IrI)。结果高剂量组的高亲和力胰岛素受体结合常数(k1)为(4.76±0.08)x108l/MOl,低亲和力胰岛素受体结合常数(k2)与结合容量(r2)分别为(1.10±0.14)x106l/MOl,(8.49±0.43)x1013/Mg蛋白,均较糖尿病对照组显著性升高(P<0.05)。补镁第3 W开始高剂量组空腹血糖较糖尿病对照组显著性降低,高剂量组的胰岛素敏感指数较糖尿病对照组显著性升高,而胰岛素抵抗指数则显著性降低。结论镁补充可以提高2型糖尿病大鼠胰岛素受体亲和力,降低胰岛素抵抗。Objective To observe the influence of magnesium supplementation on the infinity of insulin receptor in rats with type 2 diabetes mellitus.Method The rats with type 2 diabetes mellitus were induced with high fat diet and intraperitoneal injection with small dose of STZ.They were randomly divided into 4 groups,i.e.high,medium,low magnesium(2000,1000,200 mg/kg Mg2+) supplementation groups and diabetes mellitus control group.FPG was measured weekly.All rats were killed after 4 w,and liver cells were tested with radiation receptor analysis of their combination constants and combined capacity.The serum insulin(Ins) level was determined with radioimmunoassay.FPG,glycosylated hemoglobin(HbA1c) and plasma malondialdehyde(MDA) were also measured,and insulin resistance index(IRI) and insulin sensitivity index(ISI) were calculated.Results: High affinity insulin receptor combination constant(K1),low affinity insulin receptor combination constant(K2) and combination capacity(R2) of high dosage group were(4.76±0.08)×108 L/ mol,(1.10±0.14)×106 L/ mol,(8.49±0.43)×1013 /mg protein respectively,significantly increased than those in diabetes mellitus control group(P<0.05).FPG was decreased since the 3th week during magnesium supplementation.The insulin sensitivity index(ISI) of high dosage group was significantly increased than that of model control group,but insulin resistance index(IRI) was decreased.Conclusion Magnesium supplementation could improve insulin receptor affinity and reduce insulin resistance in type 2 diabetic rats

用环境扫描电子显微镜研究vero细胞在微载体上的生长

使用环境扫描电子显微镜（ESEM）,通过观察Vero细胞在Cytodex-3微载体表面上贴附铺展及增殖生长过程中的形态变化,分析了细胞在微载体上的贴附与铺展的过程和行为;考察了外源的层/纤粘连蛋白对细胞铺展形貌的影响,发现细胞在微载体上的增殖生长以细胞群落延伸扩展的形式进行.用ESEM 图像计数法和结晶紫细胞核计数法获得细胞生长过程的细胞密度变化和生长曲线,研究了接种密度对细胞生长过程的影响,随着接种密度的增大,细胞延迟期缩短,表观生长速率增大,细胞长满微载体表面所用的时间缩短.在实验的血清浓度范围内（5％～10％）,血清浓度影响细胞的贴附,随着血清浓度的增大,细胞的贴附率增加,从而影响整个生长过程

用环境扫描电子显微镜研究Vero细胞在微载体上的生长

使用环境扫描电子显微镜（ESEM）,通过观察Vero细胞在Cytodex-3微载体表面上贴附铺展及增殖生长过程中的形态变化,分析了细胞在微载体上的贴附与铺展的过程和行为;考察了外源的层/纤粘连蛋白对细胞铺展形貌的影响,发现细胞在微载体上的增殖生长以细胞群落延伸扩展的形式进行.用ESEM 图像计数法和结晶紫细胞核计数法获得细胞生长过程的细胞密度变化和生长曲线,研究了接种密度对细胞生长过程的影响,随着接种密度的增大,细胞延迟期缩短,表观生长速率增大,细胞长满微载体表面所用的时间缩短.在实验的血清浓度范围内（5％～10％）,血清浓度影响细胞的贴附,随着血清浓度的增大,细胞的贴附率增加,从而影响整个生长过程

EFFECTS of MAGNESIUM INTAKE ON ANTI-OXIDATIVE ACTIVITY IN RATS WITH TYPE-2 DIABETIC RATS

目的观察补镁对2型糖尿病大鼠抗氧化能力和糖脂代谢的影响。方法高脂饲料喂养加链脲佐菌素注射方法制备2型糖尿病大鼠模型,然后氧化镁高、中、低剂量组在高脂饲料中分别加入氧化镁2 000、1 000、200Mg/kg(以镁离子计)喂饲,糖尿病组只喂饲高脂饲料,正常对照组喂饲普通饲料。动物自由进食,连续4周,采用葡萄糖氧化酶法测定大鼠空腹尾尖血的血糖含量,腹主动脉取血测定空腹三酰甘油(Tg)、血镁、胰岛素、总抗氧化能力(T-AOC)、超氧化物歧化酶(SOd)及丙二醛(MdA)水平。结果与糖尿病组比较,氧化镁高剂量组SOd和T-AOC水平显著升高,而MdA、空腹血糖和Tg水平明显降低,差异均有显著性(f=9.96~41.05,T=2.55~29.27,P<0.05)。结论补充镁可以提高2型糖尿病大鼠抗氧化能力,改善糖脂代谢。Objective To investigate the effect of magnesium intake on anti-oxidative activity and glucolipid metabolism in type-2 diabetic rats.MethodsA model of type-2 diabetes was created in rats by feeding with high fat forage plus injection of streptozotocin.The rats in high-fat-diet groups were given magnesium oxide at a dose of 2 000,1 000 and 200 mg/kg(based on magnesium ion) to rats in high-,median-and low-magnesium-oxide group.For those in model group,high fat diet only was given,those in the control group,fed with ordinary forage only.All the rats took food unconventionally for four weeks.Fasting blood glucose in tail ending was detected by glucose oxidase method.The blood taken from abdominal aorta was used to measure fasting triacylglycerol(TG),the levels of magnesium,insulin,total antioxidative capability(T-AOC),superoxide dismutase(SOD) and malondialdehyde(MDA).ResultsCompared with the model group,SOD and T-AOC in high-magnesium-oxide group obviously increased,and MDA,blood glucose and TG decreased(F=9.96-41.05,t=2.55-29.27,P<0.05).ConclusionSupplementary of magnesium may increase anti-oxidative activityin rats with type-2 diabetes,and improve glucolipid metabolism