22 research outputs found
Ispitivanje faktora povezanih sa težinom simptoma bolesnika sa nosnosinusnom polipozom
Uvod. HroniÄni rinosinuzitis sa nosnosinusnom polipozom je hroniÄni upalniproces sluznice nosnih i paranazalnih sinusa koji se kliniÄki manifestujepojavom polipoznih masa u nosnoj Å”upljini. Prisustvo polipa u nosnimi paranazalnim Å”upljinama izaziva karakteristiÄne simptome koji utiÄu nakvalitet života pacijenta. U ovoj studiji je ispitana povezanost izmeÄu endoskopskog,mikrobioloÅ”kog, radioloÅ”kog nalaza i težine simptoma pacijenatasa hroniÄnim rinosinuzitisom i nosnosinusnom polipozom.Metode. Istraživanjem je obuhvaÄeno 45 pacijenata sa hroniÄnim rinosinuzitisomi nosnosinusnom polipozom, kod kojih je indikovano operativnolijeÄenje nakon neuspjeha konzervativne terapije i 25 ispitanika kontrolnegrupe. Intenzitet simptoma kod ispitanika je procjenjivan na osnovu vizuelneanalogne skale. Svim bolesnicima je uraÄeno bakterioloÅ”ko ispitivanjesekreta srednjeg nosnog hodnika. KliniÄka i radioloÅ”ka procjena težineoboljenja je vrÅ”ena na osnovu endoskopskog i skora kompjuterizovanetomografije (CT).Rezultati. Utvrdili smo znaÄajnu statistiÄku razliku u težini simptoma izmeÄueksperimetalne i kontrolnu grupe. Endoskopski skor je statistiÄki znaÄajnokorelirao sa težinom simptoma (r = 0,315; p = 0,035), CT-skorom (r = 0,720;p < 0,001) i prisustvom astme (r = 0,335; p = 0,025)). CT skor je statistiÄkiznaÄajno korelirao sa prisustvom astme (r = 0,419; p = 0,004). Binarnom logistiÄkomregresijom smo utvrdili statistiÄki znaÄajnu povezanost izmeÄuendoskopskog skora i težine simptoma (OR = 1,513; p = 0,044).ZakljuÄak. U odnosu na objektivne kliniÄke parametre, težina simptomakod pacijenata sa nosnosinusnom polipozom statistiÄki znaÄajno korelirasa endoskopskim skorom
PraÄenje onkoloÅ”kih bolesnika ā kliniÄke preporuke Hrvatskog druÅ”tva za internistiÄku onkologiju HLZ-a II. dio: rak bubrega, rak mokraÄnog mjehura, rak prostate, rak testisa [Cancer patients follow-up ā Croatian society of medical oncology clinical guidelines Part II: renal cell cancer, urinary bladder cancer, prostate cancer, testicular cancer]
The treatment of oncological patients must be based upon multidisciplinary approach, and takes place in specialized oncological centers. By the end of a specific oncological treatment further follow-up is being managed mostly by the oncologists, but the role of the general practitioners becomes more important every day and therefore should be precisely defined. Nowadays, most of the existing follow-up guidelines are not based on prospective studies, but on the experts opinion of individual oncological centers or specialists. The aim of the Croatian Society of Medical Oncology (CSMO) with these recommendations is to standardize and rationalize the diagnostic procedures algorithm in the followāup of Āoncological patients after primary treatment, in patients with renal cell cancer, urinary bladder cancer, prostate cancer and testicular cancer
CANCER PATIENTS FOLLOW-UP ā CROATIAN SOCIETY OF MEDICAL ONCOLOGY CLINICAL GUIDELINES Part II: renal cell cancer, urinary bladder cancer, prostate cancer, testicular cancer
LijeÄenje onkoloÅ”kih bolesnika mora se temeljiti na multidisciplinarnom pristupu, a provodi se u specijaliziranim onkoloÅ”kim centrima. Nakon zavrÅ”etka specifiÄnog onkoloÅ”kog lijeÄenja daljnje praÄenje uglavnom provode onkolozi, ali je uloga lijeÄnika primarne zdravstvene zaÅ”tite (PZZ) sve važnija i potrebno ju je jasno definirati. TrenutaÄno se veÄina preporuka za praÄenje ne temelji na prospektivnim studijama, veÄ se zasniva na struÄnim miÅ”ljenjima pojedinih onkoloÅ”kih centara ili specijalista. Hrvatsko druÅ”tvo za internistiÄku onkologiju (HDIO) ovim preporukama želi standardizirati i racionalizirati dijagnostiÄke postupke u praÄenju onkoloÅ”kih bolesnika nakon zavrÅ”etka primarnog lijeÄenja, u bolesnika s Ārakom bubrega, rakom mokraÄnog mjehura, rakom prostate i rakom testisa.The treatment of oncological patients must be based upon multidisciplinary approach, and takes place in specialized oncological centers. By the end of a specific oncological treatment further follow-up is being managed mostly by the oncologists, but the role of the general practitioners becomes more important every day and therefore should be precisely defined. Nowadays, most of the existing follow-up guidelines are not based on prospective studies, but on the experts opinion of individual oncological centers or specialists. The aim of the Croatian Society of Medical Oncology (CSMO) with these recommendations is to standardize and rationalize the diagnostic procedures algorithm in the followāup of Āoncological patients after primary treatment, in patients with renal cell cancer, urinary bladder cancer, prostate cancer and testicular cancer
CLINICAL RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER
Rak dojke najÄeÅ”Äa je maligna bolest u žena. Razvoj preventivnih mjera i dijagnostike i svih oblika lijeÄenja (kirurgije, radioterapije, kemoterapije, hormonske i ciljane bioloÅ”ke terapije) doveo je do produljenja preživljenja i poboljÅ”anja kvalitete života bolesnica. S ciljem optimalizacije i standardizacije lijeÄenja, a slijedeÄi smjernice medicine temeljene na dokazima, donosimo smjernice za dijagnostiku, lijeÄenje i praÄenje bolesnica s rakom dojke koje su rezultat rada multidisciplinarnog tima struÄnjaka.Breast cancer is the most common malignancy in women. Preventive measures, early diagnosis and development of all treatment modalities (surgery, radiotherapy, chemotherapy, hormonal and targeted biologic therapy) led to improvement in survival and quality of life of the patient. In order to standardize and optimize the approach, following good clinical practice standards, we bring consensus guidelines for diagnosis, treatment and monitoring of breast cancer patients as a result of consensus of a multidisciplinary team of experts for breast cancer
CLINICAL RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER
Rak dojke najÄeÅ”Äa je maligna bolest u žena. Razvoj preventivnih mjera i dijagnostike i svih oblika lijeÄenja (kirurgije, radioterapije, kemoterapije, hormonske i ciljane bioloÅ”ke terapije) doveo je do produljenja preživljenja i poboljÅ”anja kvalitete života bolesnica. S ciljem optimalizacije i standardizacije lijeÄenja, a slijedeÄi smjernice medicine temeljene na dokazima, donosimo smjernice za dijagnostiku, lijeÄenje i praÄenje bolesnica s rakom dojke koje su rezultat rada multidisciplinarnog tima struÄnjaka.Breast cancer is the most common malignancy in women. Preventive measures, early diagnosis and development of all treatment modalities (surgery, radiotherapy, chemotherapy, hormonal and targeted biologic therapy) led to improvement in survival and quality of life of the patient. In order to standardize and optimize the approach, following good clinical practice standards, we bring consensus guidelines for diagnosis, treatment and monitoring of breast cancer patients as a result of consensus of a multidisciplinary team of experts for breast cancer
CLINICAL GUIDELINES FOR DIAGNOSING, TREATMENT AND MONITORING PATIENTS WITH PROSTATE CANCER ā CROATIAN ONCOLOGY SOCIETY AND CROATIAN UROLOGY SOCIETY, CROATIAN MEDICAL ASSOCIATION
Adenokarcinom prostate druga je po uÄestalosti zloÄudna neoplazija u muÅ”karaca u Republici Hrvatskoj. KliniÄki je Äesto asimptomatski, a najÄeÅ”Äe se otkriva na osnovi poviÅ”enih vrijednosti PSA u serumu. Odluka o lijeÄenju donosi se na osnovi TNM-klasifikacije, Gleasonova gradusa (stupnja diferenciranosti) i vrijednosti PSA. KliniÄki lokalizirana bolest lijeÄi se vrlo uspjeÅ”no radikalnom prostatektomijom ili radikalnom radioterapijom s hormonskom terapijom ili bez nje. KliniÄki lokalno uznapredovala bolest najÄeÅ”Äe se lijeÄi združenom primjenom radikalne radioterapije i hormonske terapije. Metastatska bolest može se godinama kontrolirati androgenom deprivacijom, a nakon razvoja bolesti rezistentne na kastraciju opravdana je kemoterapija ili dodatni oblici hormonske terapije. U tekstu koji slijedi predstavljene su kliniÄke upute s ciljem standardizacije postupaka i kriterija postavljanja dijagnoze, lijeÄenja te praÄenja bolesnika s rakom prostate u Republici Hrvatskoj.Prostate adenocarcinoma is the second most common solid neoplasm in male population in Croatia. It rarely causes symptoms unless it is advanced. The finding of PSA rise is the most common reason for diagnostic workout. Treatment plan is based on TNM classification, Gleason score and PSA. Clinically localized disease is successfully treated by radical prostatectomy or radiotherapy with or without hormonal therapy. Locally advanced disease is treated with radiotherapy and hormonal therapy. Metastatic disease can be controlled for many years by androgen deprivation. For castration resistant disease appropriate treatment is chemotherapy or secondary hormonal therapy. The following paper presents the clinical guidelines in order to standardize procedures and criteria for the diagnosis, management, management, treatment and monitoring of patients with prostate cancer in the Republic of Croatia
CLINICAL GUIDELINES FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER ā CROATIAN ONCOLOGY SOCIETY
Rak dojke najÄeÅ”Äi je zloÄudni tumor u žena koji se može probirom, redovitim kontrolama i zdravstvenim odgojem otkriti u ranim stadijima bolesti i uspjeÅ”no lijeÄiti. Metode lijeÄenja ukljuÄuju kirurgiju, kemoterapiju, radioterapiju, hormonsku terapiju i ciljanu bioloÅ”ku terapiju ovisno o stadiju bolesti, bioloÅ”kim obilježjima tumora i opÄem stanju bolesnice. Odluku o lijeÄenju donosi multidisciplinarni tim. S obzirom na važnost ove bolesti, potrebno je definirati i provoditi standardizirani pristup u dijagnostici, lijeÄenju i praÄenju ovih bolesnica. U tekstu koji slijedi iznesene su kliniÄke smjernice s ciljem implementacije standardiziranih postupaka u radu s bolesnicama s rakom dojke u Republici Hrvatskoj.Breast cancer is the most common cancer in women. It can be diagnosed in early stage through screening, early detection and educational programs, and when diagnosed early it can be efficiently treated. Treatment modalities include surgery, chemotherapy, radiotherapy, hormonal therapy and targeted biologic therapy, according to the stage of the disease and patient condition. Treatment decisions should be made after multidisciplinary team discussion. Due to the significance of this disease it is important to define and implement standardized approach for diagnostic, treatment and monitoring algorithm as well. The following text presents the clinical guidelines in order to standardize the procedures and criteria for diagnosis, management, treatment and monitoring of patients with breast cancer in the Republic of Croatia