22 research outputs found

    Ispitivanje faktora povezanih sa težinom simptoma bolesnika sa nosnosinusnom polipozom

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    Uvod. Hronični rinosinuzitis sa nosnosinusnom polipozom je hronični upalniproces sluznice nosnih i paranazalnih sinusa koji se klinički manifestujepojavom polipoznih masa u nosnoj Å”upljini. Prisustvo polipa u nosnimi paranazalnim Å”upljinama izaziva karakteristične simptome koji utiču nakvalitet života pacijenta. U ovoj studiji je ispitana povezanost između endoskopskog,mikrobioloÅ”kog, radioloÅ”kog nalaza i težine simptoma pacijenatasa hroničnim rinosinuzitisom i nosnosinusnom polipozom.Metode. Istraživanjem je obuhvaćeno 45 pacijenata sa hroničnim rinosinuzitisomi nosnosinusnom polipozom, kod kojih je indikovano operativnoliječenje nakon neuspjeha konzervativne terapije i 25 ispitanika kontrolnegrupe. Intenzitet simptoma kod ispitanika je procjenjivan na osnovu vizuelneanalogne skale. Svim bolesnicima je urađeno bakterioloÅ”ko ispitivanjesekreta srednjeg nosnog hodnika. Klinička i radioloÅ”ka procjena težineoboljenja je vrÅ”ena na osnovu endoskopskog i skora kompjuterizovanetomografije (CT).Rezultati. Utvrdili smo značajnu statističku razliku u težini simptoma izmeđueksperimetalne i kontrolnu grupe. Endoskopski skor je statistički značajnokorelirao sa težinom simptoma (r = 0,315; p = 0,035), CT-skorom (r = 0,720;p < 0,001) i prisustvom astme (r = 0,335; p = 0,025)). CT skor je statističkiznačajno korelirao sa prisustvom astme (r = 0,419; p = 0,004). Binarnom logističkomregresijom smo utvrdili statistički značajnu povezanost izmeđuendoskopskog skora i težine simptoma (OR = 1,513; p = 0,044).Zaključak. U odnosu na objektivne kliničke parametre, težina simptomakod pacijenata sa nosnosinusnom polipozom statistički značajno korelirasa endoskopskim skorom

    Praćenje onkoloÅ”kih bolesnika ā€“ kliničke preporuke Hrvatskog druÅ”tva za internističku onkologiju HLZ-a II. dio: rak bubrega, rak mokraćnog mjehura, rak prostate, rak testisa [Cancer patients follow-up ā€“ Croatian society of medical oncology clinical guidelines Part II: renal cell cancer, urinary bladder cancer, prostate cancer, testicular cancer]

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    The treatment of oncological patients must be based upon multidisciplinary approach, and takes place in specialized oncological centers. By the end of a specific oncological treatment further follow-up is being managed mostly by the oncologists, but the role of the general practitioners becomes more important every day and therefore should be precisely defined. Nowadays, most of the existing follow-up guidelines are not based on prospective studies, but on the experts opinion of individual oncological centers or specialists. The aim of the Croatian Society of Medical Oncology (CSMO) with these recommendations is to standardize and rationalize the diagnostic procedures algorithm in the followā€“up of Ā­oncological patients after primary treatment, in patients with renal cell cancer, urinary bladder cancer, prostate cancer and testicular cancer

    CANCER PATIENTS FOLLOW-UP ā€“ CROATIAN SOCIETY OF MEDICAL ONCOLOGY CLINICAL GUIDELINES Part II: renal cell cancer, urinary bladder cancer, prostate cancer, testicular cancer

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    Liječenje onkoloÅ”kih bolesnika mora se temeljiti na multidisciplinarnom pristupu, a provodi se u specijaliziranim onkoloÅ”kim centrima. Nakon zavrÅ”etka specifičnog onkoloÅ”kog liječenja daljnje praćenje uglavnom provode onkolozi, ali je uloga liječnika primarne zdravstvene zaÅ”tite (PZZ) sve važnija i potrebno ju je jasno definirati. Trenutačno se većina preporuka za praćenje ne temelji na prospektivnim studijama, već se zasniva na stručnim miÅ”ljenjima pojedinih onkoloÅ”kih centara ili specijalista. Hrvatsko druÅ”tvo za internističku onkologiju (HDIO) ovim preporukama želi standardizirati i racionalizirati dijagnostičke postupke u praćenju onkoloÅ”kih bolesnika nakon zavrÅ”etka primarnog liječenja, u bolesnika s Ā­rakom bubrega, rakom mokraćnog mjehura, rakom prostate i rakom testisa.The treatment of oncological patients must be based upon multidisciplinary approach, and takes place in specialized oncological centers. By the end of a specific oncological treatment further follow-up is being managed mostly by the oncologists, but the role of the general practitioners becomes more important every day and therefore should be precisely defined. Nowadays, most of the existing follow-up guidelines are not based on prospective studies, but on the experts opinion of individual oncological centers or specialists. The aim of the Croatian Society of Medical Oncology (CSMO) with these recommendations is to standardize and rationalize the diagnostic procedures algorithm in the followā€“up of Ā­oncological patients after primary treatment, in patients with renal cell cancer, urinary bladder cancer, prostate cancer and testicular cancer

    CLINICAL RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER

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    Rak dojke najčeŔća je maligna bolest u žena. Razvoj preventivnih mjera i dijagnostike i svih oblika liječenja (kirurgije, radioterapije, kemoterapije, hormonske i ciljane bioloÅ”ke terapije) doveo je do produljenja preživljenja i poboljÅ”anja kvalitete života bolesnica. S ciljem optimalizacije i standardizacije liječenja, a slijedeći smjernice medicine temeljene na dokazima, donosimo smjernice za dijagnostiku, liječenje i praćenje bolesnica s rakom dojke koje su rezultat rada multidisciplinarnog tima stručnjaka.Breast cancer is the most common malignancy in women. Preventive measures, early diagnosis and development of all treatment modalities (surgery, radiotherapy, chemotherapy, hormonal and targeted biologic therapy) led to improvement in survival and quality of life of the patient. In order to standardize and optimize the approach, following good clinical practice standards, we bring consensus guidelines for diagnosis, treatment and monitoring of breast cancer patients as a result of consensus of a multidisciplinary team of experts for breast cancer

    CLINICAL RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER

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    Rak dojke najčeŔća je maligna bolest u žena. Razvoj preventivnih mjera i dijagnostike i svih oblika liječenja (kirurgije, radioterapije, kemoterapije, hormonske i ciljane bioloÅ”ke terapije) doveo je do produljenja preživljenja i poboljÅ”anja kvalitete života bolesnica. S ciljem optimalizacije i standardizacije liječenja, a slijedeći smjernice medicine temeljene na dokazima, donosimo smjernice za dijagnostiku, liječenje i praćenje bolesnica s rakom dojke koje su rezultat rada multidisciplinarnog tima stručnjaka.Breast cancer is the most common malignancy in women. Preventive measures, early diagnosis and development of all treatment modalities (surgery, radiotherapy, chemotherapy, hormonal and targeted biologic therapy) led to improvement in survival and quality of life of the patient. In order to standardize and optimize the approach, following good clinical practice standards, we bring consensus guidelines for diagnosis, treatment and monitoring of breast cancer patients as a result of consensus of a multidisciplinary team of experts for breast cancer

    CLINICAL GUIDELINES FOR DIAGNOSING, TREATMENT AND MONITORING PATIENTS WITH PROSTATE CANCER ā€“ CROATIAN ONCOLOGY SOCIETY AND CROATIAN UROLOGY SOCIETY, CROATIAN MEDICAL ASSOCIATION

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    Adenokarcinom prostate druga je po učestalosti zloćudna neoplazija u muÅ”karaca u Republici Hrvatskoj. Klinički je često asimptomatski, a najčeŔće se otkriva na osnovi poviÅ”enih vrijednosti PSA u serumu. Odluka o liječenju donosi se na osnovi TNM-klasifikacije, Gleasonova gradusa (stupnja diferenciranosti) i vrijednosti PSA. Klinički lokalizirana bolest liječi se vrlo uspjeÅ”no radikalnom prostatektomijom ili radikalnom radioterapijom s hormonskom terapijom ili bez nje. Klinički lokalno uznapredovala bolest najčeŔće se liječi združenom primjenom radikalne radioterapije i hormonske terapije. Metastatska bolest može se godinama kontrolirati androgenom deprivacijom, a nakon razvoja bolesti rezistentne na kastraciju opravdana je kemoterapija ili dodatni oblici hormonske terapije. U tekstu koji slijedi predstavljene su kliničke upute s ciljem standardizacije postupaka i kriterija postavljanja dijagnoze, liječenja te praćenja bolesnika s rakom prostate u Republici Hrvatskoj.Prostate adenocarcinoma is the second most common solid neoplasm in male population in Croatia. It rarely causes symptoms unless it is advanced. The finding of PSA rise is the most common reason for diagnostic workout. Treatment plan is based on TNM classification, Gleason score and PSA. Clinically localized disease is successfully treated by radical prostatectomy or radiotherapy with or without hormonal therapy. Locally advanced disease is treated with radiotherapy and hormonal therapy. Metastatic disease can be controlled for many years by androgen deprivation. For castration resistant disease appropriate treatment is chemotherapy or secondary hormonal therapy. The following paper presents the clinical guidelines in order to standardize procedures and criteria for the diagnosis, management, management, treatment and monitoring of patients with prostate cancer in the Republic of Croatia

    CLINICAL GUIDELINES FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH INVASIVE BREAST CANCER ā€“ CROATIAN ONCOLOGY SOCIETY

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    Rak dojke najčeŔći je zloćudni tumor u žena koji se može probirom, redovitim kontrolama i zdravstvenim odgojem otkriti u ranim stadijima bolesti i uspjeÅ”no liječiti. Metode liječenja uključuju kirurgiju, kemoterapiju, radioterapiju, hormonsku terapiju i ciljanu bioloÅ”ku terapiju ovisno o stadiju bolesti, bioloÅ”kim obilježjima tumora i općem stanju bolesnice. Odluku o liječenju donosi multidisciplinarni tim. S obzirom na važnost ove bolesti, potrebno je definirati i provoditi standardizirani pristup u dijagnostici, liječenju i praćenju ovih bolesnica. U tekstu koji slijedi iznesene su kliničke smjernice s ciljem implementacije standardiziranih postupaka u radu s bolesnicama s rakom dojke u Republici Hrvatskoj.Breast cancer is the most common cancer in women. It can be diagnosed in early stage through screening, early detection and educational programs, and when diagnosed early it can be efficiently treated. Treatment modalities include surgery, chemotherapy, radiotherapy, hormonal therapy and targeted biologic therapy, according to the stage of the disease and patient condition. Treatment decisions should be made after multidisciplinary team discussion. Due to the significance of this disease it is important to define and implement standardized approach for diagnostic, treatment and monitoring algorithm as well. The following text presents the clinical guidelines in order to standardize the procedures and criteria for diagnosis, management, treatment and monitoring of patients with breast cancer in the Republic of Croatia
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