Predictor Relations between Owned Values, Self-Efficacy for Protecting from Substance Abuse and Future Expectations among Adolescents

The aim of the research is to present precursor relations between the values which teenagers have, future expectations and self-efficacy of protection from drug abuse and test the model created with reference to these relations. The research is done in Accord with relational scanning which is a sub-genre of general scanning model. Study group of the research is selected by random sampling method from teenagers who have training in five different schools, one is a student at a vocational high school and four are a student at four Anatolian high schools, and in class levels in Konya in 2014-2015 academic year. 318 out of them is female students and 252 out of them is male students. Humanitarian Values Scale (HVS) developed by Dilmaç (2007), Self-Efficacy Scale of Protection from Drug Abuse (2013) developed by Eker, Akkuş and Kapısız (2013) and Teenagers’ Future Expectations Scale adapted by Tuncer (2011) into Turkish are used in the research. The research is used by using the AMOS 19 program according to “Structural Equation Model”. According to findings obtained from the research, it is seen that the values have direct impacts on self-efficacy of protection from drug abuse and future expectations and that future expectations have direct impact on self-efficacy of protection from drug abuse

The role of theory of mind, emotion knowledge and empathy in preschoolers’ disruptive behavior

Objectives : Research examining disruptive behaviors in clinical groups of preschool and school-aged children has consistently revealed significant difficulties in their emotion knowledge and empathy but intact performance in their theory-of-mind (ToM). However, it is largely not known if these difficulties in emotion knowledge and empathy as opposed to ToM are specific to extreme forms of disruption in clinical groups or rather represent broad deficiencies related to disruptive behaviors in general, including the milder levels exhibited by typically developing children. Milder disruptive behaviors (e.g., whining, arguing, rule-breaking and fighting) in peer contexts might relate to normative variations in socio-cognitive and emotional skills like ToM, emotion knowledge and empathy. To illuminate whether the same pattern of relations observed in clinical samples would arise in typical development, this study aims to examine the role of ToM, emotion knowledge and empathy in typically developing preschoolers’ disruptive behaviors.WOS:000510437900014Scopus - Affiliation ID: 60105072Social Sciences Citation IndexQ3 - Q4ArticleOcak2020YÖK - 2019-2

Evaluating the relationship of blood pressure, plasma angiotensin peptides and aldosterone with cognitive functions in patients with hypertension

Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin peptides and aldoste- rone with cognitive functions. Forty-one patients who were under treatment with the same antihypertensive med- ications for at least three months were included in the study. Plasma angiotensin II, angiotensin 1-7, angiotensin IV, and aldosterone concentrations were analyzed using an enzyme-linked immunosorbent assay (ELISA). Stand- ardized Mini Mental State Examination (SMMSE) was used to evaluate cognitive functions. When the participants were grouped according to their SMMSE scores (cut-off value: 26 points), we determined significant differences between systolic blood pressure (SBP) levels, diastolic blood pressure levels, plasma angiotensin II and angioten- sin 1-7 concentrations of the groups. When the participants were stratified according to their SBP levels (cut-off value: 140 mm Hg), we found significant differences in SMMSE scores and plasma angiotensin IV concentrations of the groups. A negative correlation between SBP and SMMSE scores and strong linear correlations among an- giotensin peptides levels were determined. The relationship found between SBP and SMMSE in the present study was compatible with the literature. Our 33 patients were using at least one angiotensin II receptor blocker (ARB). Regarding AT1 receptor blockage, the significant association between higher SMMSE scores and increased angi- otensin peptides may support a finding that ARBs prevent dementia and improve cognitive function. Further larger studies are needed to confirm and prove the relation of RAAS biochemical parameters with cognitive function

Evaluation of intraocular pressure and retinal nerve fiber layer thickness in patients with Helicobacter pylori

Objectives: High prevalence of Helicobacter pylori (HP) in the glaucoma patients was shown in recent studies. In our prospective study we aimed to compare the intraocular pressure (IOP) and the retinal nerve fiber layer thickness (RNFLT) in patients with HP positive and negative. Methods: In 91 patients with gastritis HP was investigated by urea breath test (UBT) and biopsy sample culture Following the full ophthalmologic examination the patients’ IOP was measured by Goldmann applanation tonometry and RNFLT was measured by spectral optic coherence tomography. The patients' demographic and clinical characteristics were compared with the χ² test for categorical variables and with the Mann Whitney U test for continuous variables. Results: Of the 90 patients who meet the including criteria, HP was detected in 74 patients (27 male, 47 female) positive, and in 16 patients (7 male, 9 female) negative. Median (minimum-maximum) age values were 46 (18-79) in HP positive group and 51 (18-67) in HP negative group. One hundred forty seven eyes in 74 HP positive patients and 31 eyes in 16 HP negative patients included in the study. Median IOP values were determined 14 (7-21) mmHg in HP positive group and 14 (8-18) mmHg in HP negative group. The measurements of RNFLT in superior, temporal, inferior and nasal quadrants found to be respectively 122(98-165), 68(50-101), 135(93-188), 79(51-120) micron in HP positive group and 120(94-161), 67(43-104), 129(94-166), 76(50-97) micron in HP negative group. No statistically significant difference was found when compared IOP and RNFLT measurements between the two groups (p<0.05). Conclusion: In this study found that the IOP and RNFLT measurements of HP positive group was not show statistically significant difference compared with HP negative group. In a large case series, randomized, case-controlled, histologic and serologic studies should be done to show the relationship between HP and glaucoma

How COVID-19 changed clinical research strategies: a global survey

Objective Clinical research has faced new challenges during the COVID-19 pandemic, leading to excessive operational demands affecting all stakeholders. We evaluated the impact of COVID-19 on clinical research strategies and compared different adaptations by regulatory bodies and academic research institutions in a global context, exploring what can be learned for possible future pandemics. Methods We conducted a cross-sectional online survey and identified and assessed different COVID-19-specific adaptation strategies used by academic research institutions and regulatory bodies. Results All 19 participating academic research institutions developed and followed similar strategies, including preventive measures, manpower recruitment, and prioritisation of COVID-19 projects. In contrast, measures for centralised management or coordination of COVID-19 projects, project preselection, and funding were handled differently amongst institutions. Regulatory bodies responded similarly to the pandemic by implementing fast-track authorisation procedures for COVID-19 projects and developing guidance documents. Quality and consistency of the information and advice provided was rated differently amongst institutions. Conclusion Both academic research institutions and regulatory bodies worldwide were able to cope with challenges during the COVID-19 pandemic by developing similar strategies. We identified some unique approaches to ensure fast and efficient responses to a pandemic. Ethical concerns should be addressed in any new decision-making process

Legal and ethical framework for global health information and biospecimen exchange - an international perspective.

BACKGROUND: The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to significantly advance medical knowledge. However, sharing of such resources for international collaboration is hampered by the lack of clarity about ethical and legal requirements for transfer of data and samples across international borders. MAIN TEXT: Here, the International Clinical Trial Center Network (ICN) reports the legal and ethical requirements governing data and sample exchange (DSE) across four continents. The most recurring requirement is ethical approval, whereas only in specific conditions approval of national health authorities is required. Informed consent is not required in all sharing situations. However, waiver of informed consent is only allowed in certain countries/regions and under certain circumstances. The current legal and ethical landscape appears to be very complex and under constant evolution. Regulations differ between countries/regions and are often incomplete, leading to uncertainty. CONCLUSION: With this work, ICN illuminates the unmet need for a single international collaborative framework to facilitate DSE. Harmonising requirements for global DSE will reduce inefficiency and waste in research. There are many challenges to realising this ambitious vision, including inconsistent terminology and definitions, and heterogeneous and dynamic legal constraints. Here, we identify areas of agreement and significant difference as a necessary first step towards facilitating international collaboration. We propose the establishment of a working group to continue the comparison across jurisdictions, create a standardised glossary and define a set of basic principles and fundamental requirements for DSE

THE CLINICAL TRIALS LANDSCAPE IN TURKEY: AN EVALUATION OF THE ClinicalTrials.gov DATABASE

Objective: Clinical trials are essential tools for improving scientific knowledge and public health. With this work, it is aimed to evaluate the clinical trials landscape in Turkey

Baltaşı-Palu (Elazığ) travertenlerinin tekno-mekanik özelliklerinin belirlenmesi

TEZ5800Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 2006.Kaynakça (s. 91-92) var.x, 93 s. : res., htr. ; 29 cm.Determination technomechanic properties of Kayaönü Village (Palu-Elazığ) traverten marbles are aimed in this study. Technomechanic properties of Kayaönü Village Marbles are determined at the Rock Mechanic and Soil Mechanic Laboratory of Çukurova University Mining Engineering Department with samples are taken from Mesta Marble Quary. Finally bulk density: 2,31 gr/cm3, density: 2,61 gr/cm3, porosity: %11,5, compressive strength: 43,208MPa, impact resistance: 0,56 Nmm/mm3, friction loss: 18,3 cm3/50cm2, tensile strength: 4,67 MPa, bending strength: 8,884 MPa, point load index: 2,69 MPa were determined.Bu çalışmada Kayaönü Köyü (Palu-Elazığ) traverten mermerlerinin teknomekanik özelliklerinin belirlenmesi amaçlanmıştır. Mesta Mermer Ocağından alınan numuneler kullanılarak Çukurova Üniversitesi Maden Mühendisliği Bölümü Kaya Mekaniği ve Zemin Mekaniği Laboratuarında Kayaönü Köyü traverten mermerlerinin tekno-mekanik özellikleri saptanmıştır. Sonuçta birim hacim ağırlık: 2,31 gr/cm3, özgül ağırlık: 2,61gr/cm3, görünür porozite: %11,5, Tek eksenli basma dayanımı: 43,208 MPa, darbe dayanımı: 0,56Nmm/mm3, sürtünme ile aşınma kaybı: 18,3 cm3/50cm2, sodyum sülfat don kaybı %0,897, dolaylı çekme dayanımı: 4,67 MPa, eğilme dayanımı: 8,884 MPa, nokta yük dayanımı: 2,69 MPa bulunmuştur