Could cellular proliferation be a predictive index for the relapse of nasal polyposis and down-regulated by nasal steroid treatment?

The aim of this article is to identify the cellular mitotic activity using Ki-67 monoclonal antibody for predicting relapses of nasal polyposis after surgery. A prospective study was conducted at Kartal Training and Research Hospital Otolaryngology Department between January 2006 and September 2008. Nasal polyps were obtained from all patients and pathological materials were analyzed for the Ki-67 staining using immunohistochemistry. Patients were followed after surgery for 12 months for relapse. There was no statistically significant difference between recurrent and nonrecurrent polyps. Polyp recurrence has a multifactorial origin. Ki-67 index alone does not provide sufficient information about polyp recurrence before the operation. © 2012 Association of Otolaryngologists of India

Göller Bölgesi’nde Doğal Olarak Yetişen Prangos platychlaena (Endemik) Uçucu Yağının Kimyasal Kompozisyonu

Bu çalışma, Türkiye’nin Göller Bölgesi’nde farklı lokasyonlarda yabani olarak yetişen Prangos platychlaena (endemik) bitkisinin meyvelerinin uçucu yağ oranını ve bileşenlerini belirlemek amacıyla yürütülmüştür. Türe ait meyve örnekleri iki farklı lokasyondan (Isparta, Sütçüler/Çandır ve Burdur, Bucak/Kızılkaya) sarı olum döneminde toplanmış, meyvelerin uçucu yağları hidrodistilasyon cihazı ile elde edilirken, uçucu yağ bileşenleri ise GC-MS cihazı kullanılarak belirlenmiştir. Çandır lokasyonunda yetişen bitkilerde meyve uçucu yağ oranı%0,16±0,02, Kızılkaya lokasyonunda ise%0,25±0,06 olarak belirlenmiştir. Çandır lokasyonundan alınan meyvelerin 54 bileşenden, Kızılkaya lokasyonundan alınan meyvelerin ise 44 bileşenden oluştuğu belirlenmiş, türün meyvelerinde toplam 73 farklı bileşen tespit edilmiştir. Uçucu yağı oluşturan bileşenler ve oranları lokasyonlara göre kalitatif ve kantitatif varyasyonlar göstermiştir. Her iki lokasyonda da uçucu yağı oluşturan ana bileşenler germacrene-D (%17,08-%20,24), β-bisabolene (%7,53-%17,83), β-copaene (%0,92-%11,70), caryophyllene oxide (%6,23-%6,30), β-farnesene (%3,21-%5,66), δ-cadinene (%3,50-%3,87) ve ledane (%3,35-%3,22) olarak tespit edilmiştir. Çalışmada türün yetiştiği bölgenin ekolojik faktörlerinin, özellikle rakımın uçucu yağ oranı ve bileşenleri üzerinde önemli bir etkiye sahip olduğu anlaşılmıştır

Aseptic meningitis, venous sinus thrombosis, intracranial hypertension and callosal involvement contemporaneously in a young patient with Behçet's disease

Abstract Not Availabl

Effect of Essential Oil Applications on Sugar Beet (Beta vulgaris L.) Root Quality During Storage

This study was carried out in order to determine the effects of dill, clove and hyssop essential oils and fungicides applied on sugar beet roots on beet storage quality during the storage period. The roots of Esperanza (KWS) variety, which was produced in the experimental areas in 2019, were used in the study. Roots were treated with 100, 500 and 1000 ppm doses of dill (Anethum graveolens L.), clove (Szygium aromaticum) and hyssop (Echinophora tenuifolia) essential oils, synthetic fungicide (80% Thiram) and Tween-80 right after harvest and the roots were placed in the storage. Weight loss of roots determined at 15-day intervals from the beginning of the storage period, dry matter ratio, brix, polar sugar, reducing sugar and alpha amino nitrogen contents, phytotoxicity and fungal infection development at the end of the 3-month storage period. The applications made in the research significantly affected the post-harvest weight and quality losses in beet. Depending on the applications, the weight losses at the end of the 3-month storage period varied between 9.43-19.90%, and the weight losses in essential oil applications were lower than the control. The highest dry matter content and brix values were obtained from clove essential oil and fungicide and Tween-80 applications. While Tween-80 and fungicide applications increased the polar sugar content compared to the control, 1000 ppm clove essential oil caused a significant decrease in the polar sugar content. In the study, reducing sugar and alpha amino nitrogen contents of roots applied 1000 ppm essential oil E. tenuifolia essential oil were lower. E. tenuifolia essential oil showed the highest antifungal activity against white mold and green mold infections. It was concluded that with the application of essential oil to the roots after the harvest, both weight and quality losses and the development of fungal diseases can be reduced, however, some active substances may cause phytotoxicity in the roots

Effect of Phytohormone Applications on Fruit Yield and Essential Oil Content in Anise (Pimpinella anisum L.)

This study was carried out in 2019 to determine the effects of methyl jasmonate (MJ), gibberellic acid (GA3) and naphthalene acetic acid (NAA) applications on fruit yield and essential oil content in anise (Pimpinella anisum L.). Different concentrations of MJ (0, 0.1, 0.5 and 1 mM), GA3 (0, 50, 100 and 150 ppm) and NAA (0, 25, 50 and 100 ppm) were pulverized to the plant during the beginning of the flowering. Phytohormone applications had a statistically significant effect on the parameters examined in the study, and the effects of the applications generally varied depending on the application doses. While GA3 and NAA applications significantly increased the fruit yield and essential oil content compared to the control, high-dose MJ applications generally had a negative effect on all parameters except that the thousand-grain weight. The highest fruit yield was obtained from 100 and 150 ppm GA3 and 25 and 50 ppm NAA applications, while 1 mM MJ applications significantly reduced fruit yield compared to the control. Depending on the applications, the fruit essential oil content varied between 1.94%-2.69% and the essential oil yield varied between 1.42-3.18 L/da. While the highest essential oil yields were obtained from 100 ppm GA3 and 50 ppm NAA applications, 1 mM MJ applications caused a significant decrease in essential oil yield compared to the control

Hyperbaric oxygen as adjuvant therapy in cervical necrotizing fasciitis

Nekrotizan fasiit önemli derecede morbidite ve mortalite ile ilişkili deri ve fasyanın ciddi bir enfeksiyonudur. Nekrotizan fasiit, baş ve boyunda tutulumu nadir olarak gözlenir. Servikal nekrotizan fasiitin standart tedavisi, intravenöz antibiyotik ve acil olarak cerrahi debridman uygulamayı içerir. Hiperbarik oksijen terapisi, nekrotizan fasiitin kontrolünde adjuvant olarak kullanılmaktadır. Birçok çalışmada hiperbarik oksijen kullanıldığında daha kısa hastanede kalma süresinin olduğu, mortalitenin ve cerrahi debridman sayısınının azaldığı ileri sürülmektedir. Bu çalışmada servikal nekrotizan fasiit tanısı konmuş olup boyunda geniş bir doku defekti olu- şan ve intravenöz antibiyotik, cerrahi debridman yanında adjuvant olarak hiperbarik oksijen terapisi uygulanan bir hasta sunulmuş ve ilgili literatür gözden geçirilmiştir.Necrotizing fasciitis is a serious infection of the fascia and skin associated with considerable morbidity and mortality. Necrotizing fasciitis rarely in- volves the head and neck. The standard treatment for cervical necrotizing fasciitis includes intravenous antibiotics and prompt surgical debridement. Hyperbaric oxygen therapy is used as adjunctive therapy in managing nec- rotizing fasciitis. Several reports suggest shorter hospital duration, reduced mortality, and decreased surgical debridement when hyperbaric oxygen is used. In this report, a patient who was diagnosed with cervical necrotizing fasciitis having a large tissue defect on her neck and was administered intra- venous antibiotics, surgical debridement, and adjuvant hyperbaric oxygen therapy is presented, and the related literature has been looked through

Water-Yield Relationships of Potato in Mediterranean Climatic Conditions

This study was carried out in Isparta University of Applied Sciences, Faculty of Agriculture, Agricultural Research, and Application Farm in 2021 to determine the effect of different irrigation water levels on tuber yield and quality parameters of the Agria potato variety. Drip irrigation method was used in the study and five different irrigation water levels (S1: 120% of the seven-day ETo, S2: 90% of the seven-day ETo, S3: 60% of the seven-day ETo, S4: 30% of the seven-day ETo, S5: No irrigation except germination and emergence) were determined based on the reference evapotranspiration (ETo). Irrigation water (IW) amounts varied between 85.66-639.26 mm and evapotranspiration varied between 296.54-825.15 mm. Different amounts of IW significantly affected the vegetative growth, yield and quality parameters of potato. As irrigation water decreased, total tuber yield and marketable yield declined. Total tuber yield and marketable yield were 46.11 t/ha and 40.59 t/ha, respectively, in S1 treatment where the maximum amount of IW was applied, while they were 12.96 t/ha and 6.37 t/ha, respectively, in S5 treatment where no irrigation was applied. Logarithmic relationships were determined between evapotranspiration and total yield and between the amount of IW and total yield. Water use efficiency was determined between 43.69-55.88 kg/(ha×mm) and irrigation water use efficiency between 32.34-51.86 kg/(ha×mm) and yield response factor (ky) was calculated as 1.19

Laryngeal Granular Cell Tumor; Rare Location

Granular cell tumors are benign subcutaneous or submucosal lesions of neurogenic origin. In this case study one patient was diagnosed and treated successfully with complete surgical resection of a laryngeal granular cell tumor that was originated from the left arytenoid region that very rare location. There is no evidence of recurrence 2 years after surgery. Granular cell tumors should be considered in the differential diagnosis of laryngeal masses, particularly in the posterior glottis

Baş-Boyun Kitlelerinde İnce İğne Aspirasyon Biyopsisinin Değeri: İİAB ile Cerrahi Sonrası Patoloji Sonuçlarının Karşılaştırılması

Amaç: Baş-boyun kitlelerinin tanısında ince iğne aspirasyon biyopsisinin (İİAB) değerini ve doğruluğunu belirlemek ve İİAB ile histopatolojik sonuçlarının uyumu araştırmak amaçlanmıştır.Yöntem ve Gereç: Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Kulak Burun Boğaz kliniğine, baş-boyun kitlesi nedeniyle başvuran 47 hastanın İİAB sonuçları ile cerrahi sonrası patolojik tanıları retrospektif olarak incelendi. Bulgular: Baş-boyun kitlesi nedeniyle başvuran 47 hastanın 27’si erkek (%41.7) ve 20’si kadın (%56.3) olup, yaş ortaması 37.8 ± 21.1 yıl idi (dağılım; 3–72 yaş). Hastaların histopatolojik sonuçlarına göre baş-boyun kitlelerinin 13’ü malign ve 34’ü benign idi. Çalışmamız sonucunda benign ya da malign ayırımı yapılmadan tüm hastalarda İİAB'nin duyarlılığı %78.5, spesifisitesi %93.9 olarak bulunmuştur. İİAB'nin pozitif prediktif değer %84.6 ve negatif prediktif değer %91.1 olarak bulunmuştur. Sonuç: İİAB, baş-boyun kitlelerin cerrahi öncesi değerlendirilmesinde değerli ve güvenilir bir yardımcı yöntemdir