15 research outputs found

    Seismic Anisotropy of the Upper Crust in the Mountain Ranges of Taiwan from the TAIGER Explosion Experiment

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    Taiwan is known as a strongly anisotropic region observed from SKS 1 - 2 s delay time and other teleseismic phases. An estimate of the crustal contribution to the total anisotropy from the foliated Central Range is essential to understanding the overall teleseismic results. We used P wave arrivals from the dense seismic arrays deployed during the TAIGER active source experiments and the permanent broadband seismic stations to determine the crustal anisotropy. From the arrival time analysis as a function of azimuth, we detected a clear cos(2£c) pattern. The strength of the crustal anisotropy (0 - 15 km depth) reaches 8 - 10% and the fast direction azimuth is around 35 - 43¢X for the overall mountain ranges. The anisotropic variations from the central to the north are found in detail. The results could indicate that the upper crustal delay time contribution of teleseismic shear waves reaches up to 0.45 s. The geological data at the surface and geophysical observations imply a coherent deformation from the surface to the lower crust or even down to the upper mantle

    RomUkrSeis : seismic model of the crust and upper mantle across the Eastern Carpathians – from the Apuseni Mountains to the Ukrainian Shield

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    RomUkrSeis was carried out by a consortium of organisations, the Faculty of Geology and Geophysics and the Doctoral School of Geology of the University of Bucharest (Romania), the Subbotin Institute of Geophysics of the National Academy of Sciences of Ukraine (Kiev), the Institute of Geophysics of the Polish Academy of Sciences (Warsaw), the Deutsches GeoForschungsZentrum (Potsdam) and the School of Geosciences of the University of Aberdeen (Scotland). Financial support for drilling/shooting works on the territory of Romania came from S.C. Prospectiuni S.A. (with a special mention to former CEO Gehrig Stannard Schultz, currently at EPI Group, United Kingdom), Hunt Oil of Romania, Repsol Romania and on the territory of Ukraine from Ukrgeofizika. Participation of the Polish group in this work was supported within statutory activities No 3841/E-41/S/2014-2020 of the Ministry of Science and Higher Education of Poland. The authors express their sincere appreciation of the activities of many people who took part in field work and data acquisition. A large part of the instrumentation was provided by the Geophysical Instrument Pool of the Deutsches GeoForschungsZentrum (GFZ), Potsdam, Germany. Christian Haberland is thanked for his support and kindness facilitating the loan of this equipment to the RomUkrSeis consortium. The public domain packages GMT (Wessel and Smith, 1995) and Seismic Unix (Cohen and Stockwell Jr., 1997) were used in the preparation of maps and for seismic data processing. Tesseral Technologies Inc. (Calgary) developed the software for the full waveform modelling and we express our gratitude to their staff for technical support. The authors also wish to thank Professor Richard England (University of Leicester) and an anonymous reviewer for their constructive comments on an earlier version of this manuscript. This version is much improved as a result.Peer reviewedPostprin

    Propaganda Cinema of the Imperial Japan.

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    This work mentions the role which cinema was, in the Imperial Japan Period. It shows us the development of the invention of cinematograph , its rising popularity, the role which it took in the society of Japan, and the use of this invention in the ideological indoctrination of the Japanese. This work shows the process in which the invention of cinema developed, how it changed in turns of years and its role in the minds of the Japanese. This development was explained with the help of describing exemplary movies which were popular in this era and the undertone which it had on the society of Japan. Main movie genres which were popular in this time, and the role which it played in delivering the main ideology which was practiced by the government, was also described. Author describes the main assumptions which guided the makers of such movies, and the popularity which they earned . Exemplary movies which are recognized as the representatives of certain genres, and the government guidelines which the moviemakers had to respect, were described. Japanese opinion of the conflicts in which they participated, which was the consequence of movies was emphasized. This work can help to understand how cinema in imperial Japan was controlled, and how it changed through the censorship imposed of the Japanese government.Praca dotyczy roli jaką sprawowało kino w okresie Imperialnej Japonii. Ukazuje ona rozwój wynalazku kinematografu, jego spopularyzowanie, role jaką przyjęło w społeczeństwie Japońskim oraz wykorzystanie wynalazku kina w celach ideologicznej indoktrynacji. W pracy pokazane jest między innymi w skutek jakiego procesu wykształciło się kino w Japonii, jak zmieniało się na przełomie lat oraz jaką rolę odgrywało w świadomości Japończyków. Rozwój kina został przekazany za pomocą przytoczenia przykładów filmów popularnych w danym okresie oraz wydźwięk jaki miały w społeczeństwie Japońskim. Omówione zostały podstawowe gatunki filmowe wytworzone w danym czasie oraz jaką rolę odgrywały w przekazaniu dominującej ideologii praktykowanej przez panujące władze. Przedstawione zostały podstawowe założenia które kierowały produkcją tychże filmów, oraz popularność jaką sobie zyskały. Przytoczone zostały filmy które można uznać za przedstawicieli danych gatunków, oraz ich rozwój związany z rządowymi wytycznymi, które każdy reżyser musiał przestrzegać. Wyszczególnione zostało spojrzenie Japończyków na konflikty w których brali udział, będące konsekwencją filmów o których traktowały. Praca ta pozwoli zrozumieć jak kino Japonii było kontrolowane przez władze oraz jak zmieniało się ono w skutek cenzury narzuconej przez władze Japońskie

    Time to treatment of prostate cancer patients

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    Prostate cancer is one of the most common cancers in men. The incidence of prostate cancer increases systematically. The correlation between waiting time for oncological treatment and survival prognosis in prostate cancer is not clearly determined. The aim of the study was to estimate the waiting time from suspicion until prostate cancer diagnosis and treatment in Warmia and Mazury Voivodeship. Ninety-six consecutive prostate cancer patients treated with radical radiotherapy between November 2016 and June 2017 in the Department of Radiation Oncology of the Hospital of the Ministry of Internal Affairs with Warmia and Mazury Oncology Center in Olsztyn were included in the analysis. A questionnaire prepared especially for this study, and individual interviews with patients were used in the study. The obtained data was supplemented with medical records and hospital databases. In the case of twenty-nine men, the PSA concentration was measured due to urinary disorders, and the median time from symptoms until the first PSA test in that group was 168 days. The median time from PSA concentration > 4 ng/ml to biopsy of prostate cancer and start of treatment for all patients was 62 and 156 days, respectively. Hormone therapy was administered the quickest. A positive correlation was observed between the waiting time from histopathological confirmation of prostate cancer until treatment, and the distance from one’s place of residence to the oncological center (p < 0.05)

    The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells

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    Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them. The effect of three phenothiazine derivatives that were used as single agents and in combination with simvastatin on cell growth, apoptosis induction, activity, and expression of cyclooxygenase-2 (COX-2) in doxorubicin-resistant colon cancer cells (LoVo/Dx) was investigated. Treatment of LoVo/Dx cells by phenothiazine derivatives combined with simvastatin resulted in an increase of doxorubicin cytotoxicity and its intracellular accumulation as compared to the treatment with phenothiazine derivatives that were used as single agents. Similarly, LoVo/Dx cells treated with two-component mixture of modulators showed the reduced expression of ABCB1 (P-glycoprotein) transporter and COX-2 enzyme, both on mRNA and protein level. Reduced expression of anti-apoptotic Bcl-2 protein and increased expression of pro-apoptotic Bax were also detected. Additionally, COX-2 activity was diminished, and caspase-3 activity was increased to a higher extent by phenothiazine derivative:simvastatin mixtures than by phenothiazine derivatives themselves. Therefore, the introduction of simvastatin strengthened the anti-MDR, anti-inflammatory, and pro-apoptotic properties of phenothiazines in LoVo/Dx cells
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