An Electrophysiological Study of Peripheral Polyneuropathy in Brucellosis

Background: Brucellosis is an anthropozoonotic disease with heterogeneous clinical presentations. This study aims to investigate the peripheral nervous system (PNS) involvement in brucellosis

Estimating Time of Weed Emergence in Cucumber (Cucumis sativus L.)

Modelling is carried out for eleven major weeds in cucumber to develop estimated models for weed emergence time. Weed species were grouped according to their emergence patterns. Amaranthus retroflexus, Chenopodium album, Heliotropium europaeum, Polygonum aviculare and Solanum nigrum were early emerging, Convolvulus arvensis, Cyperus rotundus, Cynodon dactylon, Portulaca oleracea and Sorghum halepense were season long emerging Tribulus terrestris was the late emerging weed species. Different non-linear growth curves (Chapman-Richard, Weibull, logistic, Gompertz and cubic spline) fitted to the data of cumulative percent emergence for the different species and years. Cubic spline seemed the best model for many species

A Late Complication of Postpartum HELLP Syndrome: Subarachnoid Hemorrhage Developed at the Postpartum Fourth Day

HELLP syndrome is a rare complication of pregnancy which is characterized by hemolysis, elevated liver enzymes, and a low platelet count. The risk of mortality during pregnancy increases with life-threatening complications, and intracranial hemorrhage is the most significant cause of death in pregnant women who have preeclampsia. We represent a case of a 27 year old woman, with 25 weeks of pregnancy diagnosed with subarachnoid hemorrhage developed at the postpartum fouth day. Careful observation and especially rapid and careful management of hypertension can save patients with severe intracranial complications of HELLP syndrome

Rapid improvement of Henoch-Schonlein purpura associated with the treatment of Helicobacter pylori infection

Helicobacter pylori (H. pylori) are one of the most common bacterial infections, seen in humans, worldwide and their possible relationships to different diseases are a focus of attention nowadays. H. pylori may cause some extra intestinal manifestations some of which are dermatological conditions, including Henoch-Schönlein purpura (HSP), chronic urticaria and atopic dermatitis. We describe a 49-year-old man who presented with HSP triggered by gastric H. pylori infection. Treatment of H. Pylori infection was accompanied by prompt resolution of the gastrointestinal manifestations and purpuric rashes. These findings suggest a causative role for H. pylori in the occurrence of HSP

Does Subclinical Hypothyroidism Affect Dynamic Thiol/Disulfide Homeostasis and ischemia-modified Albumin Levels in Children?

karahan, irfan/0000-0003-4669-1751WOS:000561256500010PubMed: 32811603Objective: To determine the effects of subclinical hypothyroidism on oxidative stress in children. Study Design: A cross-sectional study. Place and Duration of Study: Department of Paediatrics, Paediatric Endocrinology, and General Outpatient Clinics, Kirikkale University, School of Medicine, from May 2017 to October 2018. Methodology: This study included 92 subjects aged between 2 and 18 years. The subjects were divided into two groups. Forty-seven children with subclinical hypothyroidism and 45 healthy controls were evaluated. In order to evaluate oxidative damage, native thiol, total thiol, disulfides, their ratios, and ischemia-modified albumin (IMA) levels were compared between the two groups. The relationship between TSH and IMA levels was assessed. Results: Age and gender were not significantly different in the two groups. Native thiol, total thiol, disulfides and their ratios were similar in the two groups. lschemia-modified albumin levels were significantly higher in the patient group than the controls (p<0.001). There was no correlation between TSH and IMA levels in the patient group (r=0.069 p=0.645). Conclusion: Subclinical hypothyroidism may be related to the impairment of IMA, and have a neutral effect on thiol/disulfide balance. Further research is needed to explain the effects of oxidative stress in subclinical hypothyroidism

Polypharmacy May Be the Cause of Acute Lithium Intoxication at the Second Day of Treatment

Lithium is frequently used as a mood stabilizer in patients with mood disorders. Lithium has a narrow therapeutic index and high toxicity. Predisposing factors for intoxication are advanced age, diet disturbances, comorbid medical conditions affecting heart, kidneys or central nervous system and polypharmacy. CASE REPORT: Here we present a case of a 74-year-old woman with a history of Parkinson’s disease, hypertension and bipolar disorder. She was using quetiapine, valsartan with hydrochlorothiazide and levodopa with carbidopa. She presented with altered mental status and muscle rigidity. The patient was admitted with acute lithium intoxication after her second dose of treatment. Blood lithium level increased to 3.58 mEq/L. The woman was hospitalized in the Internal Medicine Intensive Care Unit. With hydration, her symptoms resolved and her lithium level returned to normal after 118 hours. CONCLUSIONS: Prescribing physicians and emergency room physicians should be aware of conditions which may cause a decreased threshold for intoxication

Brucellosis impairs endothelial functions in chronic symptomatic patients without overt cardiac involvement

Objective: Brucellosis is an important infectious disease, especially in developing countries, and may involve any organ, including the cardiovascular system. This study aimed to assess cardiac and endothelial functions in brucellosis patients

Urotensin-II and endothelin-I levels after contrast media administration in patients undergoing percutaneous coronary interventions

Background: Contrast induced kidney injury is an acute renal dysfunction that is secondary to the administration of radio contrast media. The purpose of this study was to evaluate the levels of urotensin-II (UT-II) and endothelin-I (ET-I) after contrast media administration in patients undergoing percutaneous coronary interventions. Materials and Methods: In this prospective cohort study, we evaluated 78 patients with coronary artery disease who were scheduled for and ultimately underwent percutaneous coronary interventions. As a contrast material, nonionic contrast media was used in various amounts (70-480 mL). Blood and urine samples were obtained to measure U-II, ET-I just before and at the twenty-fourth hour of percutaneous coronary interventions. Results: Compared to baseline, twenty-fourth hour creatinine levels were significantly increased ( P < 0.001). The twenty-fourth hour serum and urine levels of both UT-II and ET-I were also significantly increased compared to baseline ( P < 0.001 for all) and 24 th hour serum and urine UT-II (r = 0.322, P = 0.004; r = 0.302, P = 0.007 respectively), ET-I (r = 0.511, P < 0.001; r = 0.266, P = 0.019 respectively) levels were significantly correlated with the amount of contrast media. Conclusion: Our study indicates that; increased UT-II and ET-I levels seem to be a consequence of hazardous effects of contrast media on blood vessels and the kidney