81 research outputs found

    Mimari Tasarımda Restorasyon ve Ulaşılabilirlik: Akreditasyon İhtiyacı

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    Diğer tüm disiplinler gibi, mimari tasarımın bir dalı olan restorasyonda da herkes için insan hak ve onuruna uygun kalitede yaşam standardının sağlanabilmesi, bilgi ve hizmetlerin mutlak ulaşılabilir olmasıyla mümkündür. Bu temel koşulun sağlıklı işleyebilmesi ve sürdürülebilirliği ise tüm bilgi ve hizmetlerin her ölçekte akredite olmasıyla güçlenerek, evrensel bir anlam kazanacaktır. Bununla birlikte, son yıllarda dünyada olduğu gibi ülkemizde de günden güne önem ve ivme kazanarak üzerinde bir çok çalışma yapılan restorasyon, ulaşılabilirlik ve akreditasyon, tasarım süreçlerinde sık sık bir arada irdelenmeye başlamıştır. Ulaşılabilirlik standartlarının; koruma kurullarında son derece disiplinli bir bakış açısıyla değerlendirilen ve tarihi yaşam kalıplarıyla şekillenmiş yapılarda uygulanabilmesi; böylece restorasyon uygulamaları sonucu yeniden işlevlendirilen tarihi binaların ulaşılabilir hale getirilmesi başlı başına bir problem arz etmektedir

    Integer programming methods for special college admissions problems

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    We develop Integer Programming (IP) solutions for some special college admission problems arising from the Hungarian higher education admission scheme. We focus on four special features, namely the solution concept of stable score-limits, the presence of lower and common quotas, and paired applications. We note that each of the latter three special feature makes the college admissions problem NP-hard to solve. Currently, a heuristic based on the Gale-Shapley algorithm is being used in the application. The IP methods that we propose are not only interesting theoretically, but may also serve as an alternative solution concept for this practical application, and also for other ones

    Optimization of facade design based on the impact of interior obstructions to daylighting

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    Overcrowding in the perimeter zone is an inevitable issue in residential rooms with limited space. Obstructions, such as furniture and household items, may block the existing windows, and therefore affect interior daylight conditions. A facade design approach is needed that simultaneously takes into account daylighting and the volume of usable space for obstructions in the perimeter zone of such rooms. This study simulates daylight distributions in a typical small residential room with obstructions in front of windows. The simulation consists of two parts. First, the effects on horizontal illuminances caused by different positions and shapes of obstructions are examined under an overcast sky. Second, the maximum usable space volumes for obstructions of 51 optimized facade configurations are calculated in terms of four window-to-wall ratios (WWRs). The results of this study show that optimizing the forms of facade design can increase the usable interior space volume and meet the daylighting requirements of Chinese standards for small residential rooms. Additionally, by using the optimized facade forms, a facade with a WWR value of 50% provides the maximum usable space for obstructions. Based on the above results, this paper presents two matrices that can help architects in selecting the appropriate fenestration methods and confirming the size of usable space and allocation for residents

    Dynamic Kidney Exchange

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    As the kidney exchange programs are being established, one important question that remains to be answered is how should the exchanges be conducted in a dynamically evolving patient pool. We study the kidney exchange problem as a dynamic matching problem, in which patient and her paired-donor arrive under a Poisson arrival process. We associate a constant unit cost of waiting in the pool for each patient, given that the alternative is continuous dialysis. We characterize the dynamically optimal two-way and unrestricted kidney exchange rules that minimize the total cost associated with the exchange pool under certain assumptions. Under the optimal two-way matching rule, all exchanges are conducted as soon as they become available. On the other hand, under the optimal unrestricted matching rule, depending on the arrival frequencies of di¤erent pairs, one of the two threshold rules can be optimal. In the …rst threshold rule, B blood-type patient and A blood-type donor pairs (B-A type) are exclusively used to be matched with reciprocal A-B type pairs instead of possibly larger exchanges, as long as the number of B-A type pairs does not exceed some threshold number. The other threshold rule is the symmetric version of the …rst one and is obtained by treating the number of A-B type pairs as the state variable instead of the B-A type

    5-(4-Bromobenzyl)-4-(4-(5-phenyl-1,3,4-oxadiazole-2-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazole-3-one: Synthesis, characterization, DFT study and antimicrobial activity

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    Since molecules containing 1,3,4-oxadiazoles and 1,2,4-triazole heterocyclic rings in their structures have important biological activities; 5-(4-Bromobenzyl)-4-(4-(5-phenyl-1,3,4-oxadiazole-2-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazole-3-one (II) was synthesized, the synthesized compound was characterized by using NMR and IR spectroscopic methods. HOMO and LUMO energies, geometrical structure parameters, IR parameters and NMR chemical shift values were calculated by using DFT method. IR and NMR experimental values were compared with DFT results. Due to the differences between experimental IR and NMR spectral values and theoretical ones, N–H?O type intermolecular strong hydrogen bond was recommended. Antimicrobial activities of the synthesized compound II was determined against fifteen different bacteria and the Leishmania major species by microdilution broth assay with Alamar Blue Dye. Compound II was found to be low effective on three different bacterial species (Minimum Inhibitory Concentration (MIC):5000 ?g/ml) and had the high antileishmanial activity (MIC: 1250 ?g/mL). In order to use the synthesized compound as a drug candidate, control studies should be performed in experimental animal models in vivo. © 202

    Mimari Tasarımda Restorasyon ve Ulaşılabilirlik: Akreditasyon İhtiyacı

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    Diğer tüm disiplinler gibi, mimari tasarımın bir dalı olan restorasyonda da herkes için insan hak ve onuruna uygun kalitede yaşam standardının sağlanabilmesi, bilgi ve hizmetlerin mutlak ulaşılabilir olmasıyla mümkündür. Bu temel koşulun sağlıklı işleyebilmesi ve sürdürülebilirliği ise tüm bilgi ve hizmetlerin her ölçekte akredite olmasıyla güçlenerek, evrensel bir anlam kazanacaktır. Bununla birlikte, son yıllarda dünyada olduğu gibi ülkemizde de günden güne önem ve ivme kazanarak üzerinde bir çok çalışma yapılan restorasyon, ulaşılabilirlik ve akreditasyon, tasarım süreçlerinde sık sık bir arada irdelenmeye başlamıştır. Ulaşılabilirlik standartlarının; koruma kurullarında son derece disiplinli bir bakış açısıyla değerlendirilen ve tarihi yaşam kalıplarıyla şekillenmiş yapılarda uygulanabilmesi; böylece restorasyon uygulamaları sonucu yeniden işlevlendirilen tarihi binaların ulaşılabilir hale getirilmesi başlı başına bir problem arz etmektedi
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